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The map label for this gene is dgk1

Identifier: 28377820

GI number: 28377820

Start: 932207

End: 932842

Strand: Direct

Name: dgk1

Synonym: lp_1011

Alternate gene names: NA

Gene position: 932207-932842 (Clockwise)

Preceding gene: 28377819

Following gene: 28377821

Centisome position: 28.18

GC content: 39.47

Gene sequence:

>636_bases
ATGCTTGTAATGTCAGGAACAATCGGTGCCGGCAAGACGAGTTTAACGCAGTTAGTGGCTAACCACTTTGGTTCTAAAGC
GTTTTACGAGTCAGTTGATGATAATCCCATTTTGCCGTTATTTTATAAGGATCCTAAGAAGTACGCCTTCTTATTACAAA
TCTATTTTTTAAATAAACGGTTAGACAGTATTAAATCAGCTTTTGCTAACGATCTGGACGTCTTAGACCGGTCGATTTTT
GAAGATTCATTATTATTTCATTTGAATGGTGATCTTGGCCGGGCGACGAATACCGAAGTTGACATTTATGATTCATTATT
AGATAACATGATGCAGGAATTGCCAGAAGCGTCTCATCAAAAGAGTCCTGATTTACTTATTCATATCAATATTTCTTTTG
ATACGATGCTCAAACGAATCCAAAAGCGGGGCCGTTCTTACGAACAAATTGATCAAGATCCTGATTTATATAAATATTAT
CAGACTTTGAATGAACGCTATGACGACTGGTACGCTAATTATGATCATAGCCCGAAGATGCAGATCGACGGGGATCAGCT
GGACTTTGTCGCCGATGCGGATGCGCGTAAGGAAGTCATTCGGTTGATCGACGAAAAAGTGGCTAGTTTAGGCTAG

Upstream 100 bases:

>100_bases
CTCACCAGATATTGCATTTTAAGACGTGGGTGCGTACAATATGTAGTGTTGCTTTTAGAGATAATCAAAATTTTGACGTG
ATTAAAAGGAGAGACGCCCC

Downstream 100 bases:

>100_bases
TTGCCTTTTTAGAATCAATGTTTTATAGTAGACAGTGAATATTAAACACGGCGCGTTTTTAAGTAGACGTTCAGAGAACC
GGTGGGTGGTGTGAATCGGT

Product: deoxyguanosine kinase

Products: NA

Alternate protein names: DGK; DGUO kinase; Deoxynucleoside kinase complex I F-component [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MLVMSGTIGAGKTSLTQLVANHFGSKAFYESVDDNPILPLFYKDPKKYAFLLQIYFLNKRLDSIKSAFANDLDVLDRSIF
EDSLLFHLNGDLGRATNTEVDIYDSLLDNMMQELPEASHQKSPDLLIHINISFDTMLKRIQKRGRSYEQIDQDPDLYKYY
QTLNERYDDWYANYDHSPKMQIDGDQLDFVADADARKEVIRLIDEKVASLG

Sequences:

>Translated_211_residues
MLVMSGTIGAGKTSLTQLVANHFGSKAFYESVDDNPILPLFYKDPKKYAFLLQIYFLNKRLDSIKSAFANDLDVLDRSIF
EDSLLFHLNGDLGRATNTEVDIYDSLLDNMMQELPEASHQKSPDLLIHINISFDTMLKRIQKRGRSYEQIDQDPDLYKYY
QTLNERYDDWYANYDHSPKMQIDGDQLDFVADADARKEVIRLIDEKVASLG
>Mature_211_residues
MLVMSGTIGAGKTSLTQLVANHFGSKAFYESVDDNPILPLFYKDPKKYAFLLQIYFLNKRLDSIKSAFANDLDVLDRSIF
EDSLLFHLNGDLGRATNTEVDIYDSLLDNMMQELPEASHQKSPDLLIHINISFDTMLKRIQKRGRSYEQIDQDPDLYKYY
QTLNERYDDWYANYDHSPKMQIDGDQLDFVADADARKEVIRLIDEKVASLG

Specific function: DGK/DAK plays an essential role in generating the deoxyribonucleotide precursors, dGTP and dATP, for DNA metabolism [H]

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

Organism=Drosophila melanogaster, GI17738037, Length=180, Percent_Identity=29.4444444444444, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 24335; Mature: 24335

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVMSGTIGAGKTSLTQLVANHFGSKAFYESVDDNPILPLFYKDPKKYAFLLQIYFLNKR
CEEECCCCCCCHHHHHHHHHHHHCCHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHH
LDSIKSAFANDLDVLDRSIFEDSLLFHLNGDLGRATNTEVDIYDSLLDNMMQELPEASHQ
HHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCC
KSPDLLIHINISFDTMLKRIQKRGRSYEQIDQDPDLYKYYQTLNERYDDWYANYDHSPKM
CCCCEEEEEECCHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCE
QIDGDQLDFVADADARKEVIRLIDEKVASLG
EECCCCEEEEECCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLVMSGTIGAGKTSLTQLVANHFGSKAFYESVDDNPILPLFYKDPKKYAFLLQIYFLNKR
CEEECCCCCCCHHHHHHHHHHHHCCHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHH
LDSIKSAFANDLDVLDRSIFEDSLLFHLNGDLGRATNTEVDIYDSLLDNMMQELPEASHQ
HHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCC
KSPDLLIHINISFDTMLKRIQKRGRSYEQIDQDPDLYKYYQTLNERYDDWYANYDHSPKM
CCCCEEEEEECCHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCE
QIDGDQLDFVADADARKEVIRLIDEKVASLG
EECCCCEEEEECCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7896798; 8172906 [H]