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The map label for this gene is hsdS1

Identifier: 28377766

GI number: 28377766

Start: 872471

End: 873613

Strand: Direct

Name: hsdS1

Synonym: lp_0940

Alternate gene names: NA

Gene position: 872471-873613 (Clockwise)

Preceding gene: 28377765

Following gene: 28377767

Centisome position: 26.37

GC content: 37.71

Gene sequence:

>1143_bases
ATGAAAAACGAAAATTTAGTGCCAAAAGTGCGGTTTAAGGGGTTTAGTGACCCTTGGGAGCAGCGTAAGCTTGGAGAACT
TGGCAAAATTCAAGGCGGTGGAACTCCAGATTCAGGTATAGCAGAATATTGGGATGGAAATGTTAACTGGTTTACACCGA
CCGAGGTTTCAAATAATGGCTATTTAGAAAGTAGTAATAGGAAAATAACCAGTTTAGGATTGAAAAAGAGTTCAGCCCGT
TTAATGCCAGCTTCTACTGTACTTATTACATCTCGTGCGGGTGTCGGTAGAATGGGAATACTTAAATATCCTGCATCTAC
AAATCAAGGCTTCCAGTCATTAATTCTTAATTCTGCAACTGATGAATATTTTATTTACTCGATGCAGCCAATAATAAGCA
AACTGGCAAATAGACTAGCGTCTGGATCAACTTTCACTGAAATATCCGGTAAACAAATGGAAAAAATCGAAATTATGATT
CCAACTACTGGAGAACAAAATCGAATCAGTAGTCTAATGAAGTGCATTAATAACCTTATCGCTGCCAATGAGGATAAACT
AGAACAGTTAAAAACTCTCAAAAAGTTGATGATGCAAAAGATTTTTTCTCAGGAATGGCGCTTCAAGGGATTCACTGACC
CATGGGAGCAGCGTAAGCTTGGAGATATATCAAAAATAACTGCTGGCGGAGATATTGATAAGGATAAGCTCAGTACTCGC
GGAAGGTATCCAGTAATTGCAAATGCGTTAACTAATAATGGAGTAGTCGGCTACTATGATTCATATAAGGTAAAGGGACC
GGCTGTCACGGTTACAGGGCGTGGAGACGTGGGACATGCCAAAACAAGAATTGAAAGTTTTACTCCTATAGTAAGACTTT
TAGTGGTAAGTGCACCTAATTTTGACATTAATTTTTTGGAGAATGCAATTAATAATATCAGAATTTTTAACGAATCGACA
GGAGTCCCTCAGCTTACCGCACCTCAACTTGGTTCCTATGAATTCGAATATCCCTGTTCTAGTGAACAAGTTTGTATAGG
CAATGTACTGCATAAGATTGATAACCTTATCGCTGCCAATGAAGATAAACTAAACCAACTTAAAGAGTTGAAGAAATATT
TAATGCAAAATATGTTTGTTTAA

Upstream 100 bases:

>100_bases
TCAACGACCTACAATCTGAATTATCCGGAATGATGGCCGATTTAGTGGCGACTGACCCTGTCGCTCAACAGCAGCTTGAG
GCCATTAAGAGGATGTTACA

Downstream 100 bases:

>100_bases
ATTCATGGATTTTTTACGGGCTATCCCTACTGAACAGCGATAGTATTAATTTATTTGTAAGTGTCAATTTTAGCCAAATG
AATAATTATTCATGTATAAA

Product: type Ic restriction-modification system, HsdS subunit

Products: NA

Alternate protein names: S.MjaXP; Type I restriction enzyme MjaXP specificity protein; S protein [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MKNENLVPKVRFKGFSDPWEQRKLGELGKIQGGGTPDSGIAEYWDGNVNWFTPTEVSNNGYLESSNRKITSLGLKKSSAR
LMPASTVLITSRAGVGRMGILKYPASTNQGFQSLILNSATDEYFIYSMQPIISKLANRLASGSTFTEISGKQMEKIEIMI
PTTGEQNRISSLMKCINNLIAANEDKLEQLKTLKKLMMQKIFSQEWRFKGFTDPWEQRKLGDISKITAGGDIDKDKLSTR
GRYPVIANALTNNGVVGYYDSYKVKGPAVTVTGRGDVGHAKTRIESFTPIVRLLVVSAPNFDINFLENAINNIRIFNEST
GVPQLTAPQLGSYEFEYPCSSEQVCIGNVLHKIDNLIAANEDKLNQLKELKKYLMQNMFV

Sequences:

>Translated_380_residues
MKNENLVPKVRFKGFSDPWEQRKLGELGKIQGGGTPDSGIAEYWDGNVNWFTPTEVSNNGYLESSNRKITSLGLKKSSAR
LMPASTVLITSRAGVGRMGILKYPASTNQGFQSLILNSATDEYFIYSMQPIISKLANRLASGSTFTEISGKQMEKIEIMI
PTTGEQNRISSLMKCINNLIAANEDKLEQLKTLKKLMMQKIFSQEWRFKGFTDPWEQRKLGDISKITAGGDIDKDKLSTR
GRYPVIANALTNNGVVGYYDSYKVKGPAVTVTGRGDVGHAKTRIESFTPIVRLLVVSAPNFDINFLENAINNIRIFNEST
GVPQLTAPQLGSYEFEYPCSSEQVCIGNVLHKIDNLIAANEDKLNQLKELKKYLMQNMFV
>Mature_380_residues
MKNENLVPKVRFKGFSDPWEQRKLGELGKIQGGGTPDSGIAEYWDGNVNWFTPTEVSNNGYLESSNRKITSLGLKKSSAR
LMPASTVLITSRAGVGRMGILKYPASTNQGFQSLILNSATDEYFIYSMQPIISKLANRLASGSTFTEISGKQMEKIEIMI
PTTGEQNRISSLMKCINNLIAANEDKLEQLKTLKKLMMQKIFSQEWRFKGFTDPWEQRKLGDISKITAGGDIDKDKLSTR
GRYPVIANALTNNGVVGYYDSYKVKGPAVTVTGRGDVGHAKTRIESFTPIVRLLVVSAPNFDINFLENAINNIRIFNEST
GVPQLTAPQLGSYEFEYPCSSEQVCIGNVLHKIDNLIAANEDKLNQLKELKKYLMQNMFV

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity [H]

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 42349; Mature: 42349

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNENLVPKVRFKGFSDPWEQRKLGELGKIQGGGTPDSGIAEYWDGNVNWFTPTEVSNNG
CCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCEECCCEECCCC
YLESSNRKITSLGLKKSSARLMPASTVLITSRAGVGRMGILKYPASTNQGFQSLILNSAT
EEECCCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCCEEEECCCCCCCHHHHHHHCCCC
DEYFIYSMQPIISKLANRLASGSTFTEISGKQMEKIEIMIPTTGEQNRISSLMKCINNLI
CCEEEEEHHHHHHHHHHHHHCCCCEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHH
AANEDKLEQLKTLKKLMMQKIFSQEWRFKGFTDPWEQRKLGDISKITAGGDIDKDKLSTR
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHCCCCCCCCHHHHHCC
GRYPVIANALTNNGVVGYYDSYKVKGPAVTVTGRGDVGHAKTRIESFTPIVRLLVVSAPN
CCCCEEEEECCCCCEEEECCCEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCC
FDINFLENAINNIRIFNESTGVPQLTAPQLGSYEFEYPCSSEQVCIGNVLHKIDNLIAAN
CCHHHHHHHHHCEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCC
EDKLNQLKELKKYLMQNMFV
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNENLVPKVRFKGFSDPWEQRKLGELGKIQGGGTPDSGIAEYWDGNVNWFTPTEVSNNG
CCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCEECCCEECCCC
YLESSNRKITSLGLKKSSARLMPASTVLITSRAGVGRMGILKYPASTNQGFQSLILNSAT
EEECCCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCCEEEECCCCCCCHHHHHHHCCCC
DEYFIYSMQPIISKLANRLASGSTFTEISGKQMEKIEIMIPTTGEQNRISSLMKCINNLI
CCEEEEEHHHHHHHHHHHHHCCCCEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHH
AANEDKLEQLKTLKKLMMQKIFSQEWRFKGFTDPWEQRKLGDISKITAGGDIDKDKLSTR
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHCCCCCCCCHHHHHCC
GRYPVIANALTNNGVVGYYDSYKVKGPAVTVTGRGDVGHAKTRIESFTPIVRLLVVSAPN
CCCCEEEEECCCCCEEEECCCEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCC
FDINFLENAINNIRIFNESTGVPQLTAPQLGSYEFEYPCSSEQVCIGNVLHKIDNLIAAN
CCHHHHHHHHHCEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCC
EDKLNQLKELKKYLMQNMFV
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]