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The map label for this gene is hsdR [H]

Identifier: 28377764

GI number: 28377764

Start: 868001

End: 870874

Strand: Direct

Name: hsdR [H]

Synonym: lp_0938

Alternate gene names: 28377764

Gene position: 868001-870874 (Clockwise)

Preceding gene: 28377763

Following gene: 28377765

Centisome position: 26.24

GC content: 41.65

Gene sequence:

>2874_bases
ATGATGGCAAGTGGACATCAATCTGAGGCAGAATTAGAAAATCACCTCATTCGAAAGTTACAAAGCATTGGCTATCATTA
CGTTGAAATTCCCGATGTTGAAACGCTAAACACACATTTTCGTGCGGTCTTGAGTGAACGTAATCAAGAACGTTTAAAGG
GAACACCACTGAGTGACCGTGAATTTCAGGCCGTATTAAATGATTTGATTGGCGCTAAGACGCATTATCAAGTTGCCCAA
ATTTTACGTGGTTCGGTTGTTCAGCCAACTGGGAAAATTAATATTAAACGTGATGATGATAGCAGCTTATACCTAGAAAT
TTTTAATGGAAAACAATTTGATCAGAATATTTTTGAAGTTAGCCATCAAATGACGGTTGAAGGTCGTCATGAGAACCGCT
ATGATGTGCTGATCTTGATCAACGGGATGCCAATTGCCCAAATTGAGTTGAAGCGGCAAGGGGTTGAATTTACTCAGGCT
TTTAATCAAATTATTCGCTACCGAACTGAATCGTACGCACAAGCAAAACTCATGCGACTGGTTCAGGTATTTGTCATTTC
CAATGGCAATGAAACGCGGTATTTTGCGAATGGCGATGGTGAGTTAAATTCAAACTTCATGTTCTACTGGACGGATGAAC
ATAATAATTGGTTGAATGACTTGGACGCTTTTACGACCACTTTCTTGAGTAAACCACGGTTACATAGTTTAATCGCAAAA
TATACGGTGTTCGATAGTAGTGACCATAAAATGTTATTAATGCGGCCTTATCAAATATATGCCACTGAGGCAATTATTAA
GCAAGCTATCGATCACCCCCATGAAAATGGTTATGTGTGGCACACGACGGGTTCCGGTAAGACGATTACCTCCTTTAAGG
CCAGTCAGTTGTTATTACAAGAAACTGATGCTGAAAAGGTTATCTTCATGATTGACCGTGCCGACTTGGATATTCAGACG
GTAAAGAATTTTAGTGCCTATCTGCCTGAAACAACTGGGGGCCAGAGTCCCTTGGATCGGACTGACAATACTGCTGCATT
AGTCAAGCAGCTGTCCTCTAATGATAATGGCTTGATCGTGACGACCATTCAGAAGATGAATAATGCGGTCTCTAATGATC
GGTATAAAGATATTCTGACACCGTACCATGACCGCAAAGTGATCTTCATTGAAGATGAAAGCCATCGTAGCCAGATGGGC
GAAATGCGAAAAAACGTGAATCATTGGTTTAAGAATGCCCAACACTTTGGGTTCACTGGAACCCCGATTTTTCAACAGAA
TATGGGACCCGATGGGCGGACCACAAAAGATCTGTACGGGAATCAGTTGCATCAATACTTGATTCGTGATGCAGTTCGTG
ATGGTAACGTGCTTGGTTTTTCGATTCAGTATCTGTCGACCTTTGAGGAGACTGATCATGACATTACAGACGAACAAGTA
CCAGGAATTGATACGCAAGAGGTCTATGAGTCCGAGGAGCGATTGACCAAGATTGTTGAGCATATCCTGTTGAACCATAG
CCACATTACAAAGAATAAGCATTACAATGCAATCTTTACGGTAGCGAATACGCGCATGGCTTTAAAGTACTATCAGTTGT
TTAGAAAGTTGGATCCTGATCATAATTTGAAGGTCACGACAATCTTTACGTGGGCTGCCAATGAGGACGACAACGAGGAA
CACCAAAAACAGGATGATGTCACTTCACGGATGGGATTAGATCAAGTCGTGAAGGACTATAATCAAATGTACGGTACGGA
TTTTTCAACGGATAAATTCAAAGATTATTTTGCGGATGTTTCTAAGCGGATGCGCGATCATAATGACCAAACGCCGACGG
ATAATATTGATATTTTGATTGTTGTGAACATGTTCCTAACTGGGTTTGACTCCAAACGGTTGTCCACACTATACGTGGAT
AAAAATTTGCAATGGCACGGTTTAATCCAAGCATTTTCTCGAACCAATCGTGTTGAGGGCAAACAAAAACCATTCGGAAA
TATTATTGCTTATCGCAATATCAAAAATAAGACGGATGAGGCTGTAGCGTTGTTTTCAGACGGGGACAGTTCCGGCTTCT
TAGCACCAGATTATGATGAATTAAAAGCTGAATTTACTGACAAGATTGGCCAATTACTGACGGTGACTCCGGATGTCCAG
TCAGTGGACGACCTCTATAACCGAGGCGATGACGCACTATATGAGTTTGTGATGGCGTTTCGGGCGGTCCTCCGGGTATA
TAATCGTATTCGCGTGTATGATGATTTTGAATGGGCGCAATATGAACCTGAATTTTCGGATCAGCTGATGGAAGCCTTTC
GGGGCAAATATTTTACGGCGTATCAAACGATTTATCAACGCAAAACGCAGGAGCGCGTCTCAATATTAGATGACGTTGAC
TTTGATATCAGTCTATTGGAGACTGATACCATCAATGTTGACTATATTGTGAACTTAATCTCAGGCATTGACTTAATGTC
GTCGACCGAACGTAAGCAAGATATTCAGAAAATTGAACATTTGTTGGATAATGCGACCAATGACCAATTAAAGTCGAAGG
TTGAATTGTTGGAACAATTTTTGAATGAAGTTTTGCCAACGCTCGATACAGACGATGATATCGGCATGTCGTTGAGTAAC
TTTATGGCCGAGAGCCAGCGAGCTGCCATTAAGGGTTTTTCACAAGAACACCACCTTTCGGAAGACTTCGTTAACGAGCA
GATTTCTGACTACAACTTCTACGGTAAGACCAAGGACAAAGAGATTATTGACAAGTTAAGTGCTAATGGGCTCGGCTTTC
GAGAGAAACGGCAGGCCAAACGCGAGATTAAGGATTTTGTATCGACTATCGACCGAAAGTATTCACTAAGCTAG

Upstream 100 bases:

>100_bases
GCCTACAGCGTCAGTTAAATATGATATGATATTGGTAATTATGGAGAGTAGACTTGATTAGTATTACGGCTAATTAATAG
TCGTATAGATGGGAGGACCT

Downstream 100 bases:

>100_bases
GAGAATGAATTTAATGAGTCATATTGAACAGGCCGAACAACAGGCTGAACTACAAAAAAGATTATGGGCTGTGGCAAATG
ATCTGCGCGGTAACATGGAT

Product: type I site-specific deoxyribonuclease, HsdR subunit

Products: NA

Alternate protein names: Type I restriction enzyme R protein [H]

Number of amino acids: Translated: 957; Mature: 957

Protein sequence:

>957_residues
MMASGHQSEAELENHLIRKLQSIGYHYVEIPDVETLNTHFRAVLSERNQERLKGTPLSDREFQAVLNDLIGAKTHYQVAQ
ILRGSVVQPTGKINIKRDDDSSLYLEIFNGKQFDQNIFEVSHQMTVEGRHENRYDVLILINGMPIAQIELKRQGVEFTQA
FNQIIRYRTESYAQAKLMRLVQVFVISNGNETRYFANGDGELNSNFMFYWTDEHNNWLNDLDAFTTTFLSKPRLHSLIAK
YTVFDSSDHKMLLMRPYQIYATEAIIKQAIDHPHENGYVWHTTGSGKTITSFKASQLLLQETDAEKVIFMIDRADLDIQT
VKNFSAYLPETTGGQSPLDRTDNTAALVKQLSSNDNGLIVTTIQKMNNAVSNDRYKDILTPYHDRKVIFIEDESHRSQMG
EMRKNVNHWFKNAQHFGFTGTPIFQQNMGPDGRTTKDLYGNQLHQYLIRDAVRDGNVLGFSIQYLSTFEETDHDITDEQV
PGIDTQEVYESEERLTKIVEHILLNHSHITKNKHYNAIFTVANTRMALKYYQLFRKLDPDHNLKVTTIFTWAANEDDNEE
HQKQDDVTSRMGLDQVVKDYNQMYGTDFSTDKFKDYFADVSKRMRDHNDQTPTDNIDILIVVNMFLTGFDSKRLSTLYVD
KNLQWHGLIQAFSRTNRVEGKQKPFGNIIAYRNIKNKTDEAVALFSDGDSSGFLAPDYDELKAEFTDKIGQLLTVTPDVQ
SVDDLYNRGDDALYEFVMAFRAVLRVYNRIRVYDDFEWAQYEPEFSDQLMEAFRGKYFTAYQTIYQRKTQERVSILDDVD
FDISLLETDTINVDYIVNLISGIDLMSSTERKQDIQKIEHLLDNATNDQLKSKVELLEQFLNEVLPTLDTDDDIGMSLSN
FMAESQRAAIKGFSQEHHLSEDFVNEQISDYNFYGKTKDKEIIDKLSANGLGFREKRQAKREIKDFVSTIDRKYSLS

Sequences:

>Translated_957_residues
MMASGHQSEAELENHLIRKLQSIGYHYVEIPDVETLNTHFRAVLSERNQERLKGTPLSDREFQAVLNDLIGAKTHYQVAQ
ILRGSVVQPTGKINIKRDDDSSLYLEIFNGKQFDQNIFEVSHQMTVEGRHENRYDVLILINGMPIAQIELKRQGVEFTQA
FNQIIRYRTESYAQAKLMRLVQVFVISNGNETRYFANGDGELNSNFMFYWTDEHNNWLNDLDAFTTTFLSKPRLHSLIAK
YTVFDSSDHKMLLMRPYQIYATEAIIKQAIDHPHENGYVWHTTGSGKTITSFKASQLLLQETDAEKVIFMIDRADLDIQT
VKNFSAYLPETTGGQSPLDRTDNTAALVKQLSSNDNGLIVTTIQKMNNAVSNDRYKDILTPYHDRKVIFIEDESHRSQMG
EMRKNVNHWFKNAQHFGFTGTPIFQQNMGPDGRTTKDLYGNQLHQYLIRDAVRDGNVLGFSIQYLSTFEETDHDITDEQV
PGIDTQEVYESEERLTKIVEHILLNHSHITKNKHYNAIFTVANTRMALKYYQLFRKLDPDHNLKVTTIFTWAANEDDNEE
HQKQDDVTSRMGLDQVVKDYNQMYGTDFSTDKFKDYFADVSKRMRDHNDQTPTDNIDILIVVNMFLTGFDSKRLSTLYVD
KNLQWHGLIQAFSRTNRVEGKQKPFGNIIAYRNIKNKTDEAVALFSDGDSSGFLAPDYDELKAEFTDKIGQLLTVTPDVQ
SVDDLYNRGDDALYEFVMAFRAVLRVYNRIRVYDDFEWAQYEPEFSDQLMEAFRGKYFTAYQTIYQRKTQERVSILDDVD
FDISLLETDTINVDYIVNLISGIDLMSSTERKQDIQKIEHLLDNATNDQLKSKVELLEQFLNEVLPTLDTDDDIGMSLSN
FMAESQRAAIKGFSQEHHLSEDFVNEQISDYNFYGKTKDKEIIDKLSANGLGFREKRQAKREIKDFVSTIDRKYSLS
>Mature_957_residues
MMASGHQSEAELENHLIRKLQSIGYHYVEIPDVETLNTHFRAVLSERNQERLKGTPLSDREFQAVLNDLIGAKTHYQVAQ
ILRGSVVQPTGKINIKRDDDSSLYLEIFNGKQFDQNIFEVSHQMTVEGRHENRYDVLILINGMPIAQIELKRQGVEFTQA
FNQIIRYRTESYAQAKLMRLVQVFVISNGNETRYFANGDGELNSNFMFYWTDEHNNWLNDLDAFTTTFLSKPRLHSLIAK
YTVFDSSDHKMLLMRPYQIYATEAIIKQAIDHPHENGYVWHTTGSGKTITSFKASQLLLQETDAEKVIFMIDRADLDIQT
VKNFSAYLPETTGGQSPLDRTDNTAALVKQLSSNDNGLIVTTIQKMNNAVSNDRYKDILTPYHDRKVIFIEDESHRSQMG
EMRKNVNHWFKNAQHFGFTGTPIFQQNMGPDGRTTKDLYGNQLHQYLIRDAVRDGNVLGFSIQYLSTFEETDHDITDEQV
PGIDTQEVYESEERLTKIVEHILLNHSHITKNKHYNAIFTVANTRMALKYYQLFRKLDPDHNLKVTTIFTWAANEDDNEE
HQKQDDVTSRMGLDQVVKDYNQMYGTDFSTDKFKDYFADVSKRMRDHNDQTPTDNIDILIVVNMFLTGFDSKRLSTLYVD
KNLQWHGLIQAFSRTNRVEGKQKPFGNIIAYRNIKNKTDEAVALFSDGDSSGFLAPDYDELKAEFTDKIGQLLTVTPDVQ
SVDDLYNRGDDALYEFVMAFRAVLRVYNRIRVYDDFEWAQYEPEFSDQLMEAFRGKYFTAYQTIYQRKTQERVSILDDVD
FDISLLETDTINVDYIVNLISGIDLMSSTERKQDIQKIEHLLDNATNDQLKSKVELLEQFLNEVLPTLDTDDDIGMSLSN
FMAESQRAAIKGFSQEHHLSEDFVNEQISDYNFYGKTKDKEIIDKLSANGLGFREKRQAKREIKDFVSTIDRKYSLS

Specific function: Subunit R is required for both nuclease and ATPase activities, but not for modification [H]

COG id: COG0610

COG function: function code V; Type I site-specific restriction-modification system, R (restriction) subunit and related helicases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR014021
- InterPro:   IPR004473
- InterPro:   IPR006935
- InterPro:   IPR007409
- InterPro:   IPR022625 [H]

Pfam domain/function: PF12008 EcoR124_C; PF04313 HSDR_N; PF04851 ResIII [H]

EC number: =3.1.21.3 [H]

Molecular weight: Translated: 110793; Mature: 110793

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMASGHQSEAELENHLIRKLQSIGYHYVEIPDVETLNTHFRAVLSERNQERLKGTPLSDR
CCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHCCHHHHCCCCCCCH
EFQAVLNDLIGAKTHYQVAQILRGSVVQPTGKINIKRDDDSSLYLEIFNGKQFDQNIFEV
HHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCEEEEECCCCEEEEEEECCCCHHHHHHHH
SHQMTVEGRHENRYDVLILINGMPIAQIELKRQGVEFTQAFNQIIRYRTESYAQAKLMRL
HHHEEEECCCCCCEEEEEEECCCCEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VQVFVISNGNETRYFANGDGELNSNFMFYWTDEHNNWLNDLDAFTTTFLSKPRLHSLIAK
HHHHHEECCCCEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHH
YTVFDSSDHKMLLMRPYQIYATEAIIKQAIDHPHENGYVWHTTGSGKTITSFKASQLLLQ
HHEECCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEHHHHHHHHHH
ETDAEKVIFMIDRADLDIQTVKNFSAYLPETTGGQSPLDRTDNTAALVKQLSSNDNGLIV
HCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEE
TTIQKMNNAVSNDRYKDILTPYHDRKVIFIEDESHRSQMGEMRKNVNHWFKNAQHFGFTG
EEHHHHHHHHCCCHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCC
TPIFQQNMGPDGRTTKDLYGNQLHQYLIRDAVRDGNVLGFSIQYLSTFEETDHDITDEQV
CCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCCCCCC
PGIDTQEVYESEERLTKIVEHILLNHSHITKNKHYNAIFTVANTRMALKYYQLFRKLDPD
CCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCEEEEEECHHHHHHHHHHHHHCCCC
HNLKVTTIFTWAANEDDNEEHQKQDDVTSRMGLDQVVKDYNQMYGTDFSTDKFKDYFADV
CCEEEEEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHH
SKRMRDHNDQTPTDNIDILIVVNMFLTGFDSKRLSTLYVDKNLQWHGLIQAFSRTNRVEG
HHHHHCCCCCCCCCCCEEEEEEEHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCC
KQKPFGNIIAYRNIKNKTDEAVALFSDGDSSGFLAPDYDELKAEFTDKIGQLLTVTPDVQ
CCCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCEEEECCCHH
SVDDLYNRGDDALYEFVMAFRAVLRVYNRIRVYDDFEWAQYEPEFSDQLMEAFRGKYFTA
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEECCCHHCCCCCHHHHHHHHHCCCHHHH
YQTIYQRKTQERVSILDDVDFDISLLETDTINVDYIVNLISGIDLMSSTERKQDIQKIEH
HHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLDNATNDQLKSKVELLEQFLNEVLPTLDTDDDIGMSLSNFMAESQRAAIKGFSQEHHLS
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCH
EDFVNEQISDYNFYGKTKDKEIIDKLSANGLGFREKRQAKREIKDFVSTIDRKYSLS
HHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MMASGHQSEAELENHLIRKLQSIGYHYVEIPDVETLNTHFRAVLSERNQERLKGTPLSDR
CCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHCCHHHHCCCCCCCH
EFQAVLNDLIGAKTHYQVAQILRGSVVQPTGKINIKRDDDSSLYLEIFNGKQFDQNIFEV
HHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCEEEEECCCCEEEEEEECCCCHHHHHHHH
SHQMTVEGRHENRYDVLILINGMPIAQIELKRQGVEFTQAFNQIIRYRTESYAQAKLMRL
HHHEEEECCCCCCEEEEEEECCCCEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VQVFVISNGNETRYFANGDGELNSNFMFYWTDEHNNWLNDLDAFTTTFLSKPRLHSLIAK
HHHHHEECCCCEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHH
YTVFDSSDHKMLLMRPYQIYATEAIIKQAIDHPHENGYVWHTTGSGKTITSFKASQLLLQ
HHEECCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEHHHHHHHHHH
ETDAEKVIFMIDRADLDIQTVKNFSAYLPETTGGQSPLDRTDNTAALVKQLSSNDNGLIV
HCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEE
TTIQKMNNAVSNDRYKDILTPYHDRKVIFIEDESHRSQMGEMRKNVNHWFKNAQHFGFTG
EEHHHHHHHHCCCHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCC
TPIFQQNMGPDGRTTKDLYGNQLHQYLIRDAVRDGNVLGFSIQYLSTFEETDHDITDEQV
CCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCCCCCC
PGIDTQEVYESEERLTKIVEHILLNHSHITKNKHYNAIFTVANTRMALKYYQLFRKLDPD
CCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCEEEEEECHHHHHHHHHHHHHCCCC
HNLKVTTIFTWAANEDDNEEHQKQDDVTSRMGLDQVVKDYNQMYGTDFSTDKFKDYFADV
CCEEEEEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHH
SKRMRDHNDQTPTDNIDILIVVNMFLTGFDSKRLSTLYVDKNLQWHGLIQAFSRTNRVEG
HHHHHCCCCCCCCCCCEEEEEEEHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCC
KQKPFGNIIAYRNIKNKTDEAVALFSDGDSSGFLAPDYDELKAEFTDKIGQLLTVTPDVQ
CCCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCEEEECCCHH
SVDDLYNRGDDALYEFVMAFRAVLRVYNRIRVYDDFEWAQYEPEFSDQLMEAFRGKYFTA
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEECCCHHCCCCCHHHHHHHHHCCCHHHH
YQTIYQRKTQERVSILDDVDFDISLLETDTINVDYIVNLISGIDLMSSTERKQDIQKIEH
HHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLDNATNDQLKSKVELLEQFLNEVLPTLDTDDDIGMSLSNFMAESQRAAIKGFSQEHHLS
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCH
EDFVNEQISDYNFYGKTKDKEIIDKLSANGLGFREKRQAKREIKDFVSTIDRKYSLS
HHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA