Click here to switch to the map view.

The map label for this gene is sugE [H]

Identifier: 28377730

GI number: 28377730

Start: 827306

End: 827620

Strand: Direct

Name: sugE [H]

Synonym: lp_0898

Alternate gene names: 28377730

Gene position: 827306-827620 (Clockwise)

Preceding gene: 28377729

Following gene: 28377731

Centisome position: 25.01

GC content: 42.22

Gene sequence:

>315_bases
ATGACGTGGATTTATTTAATTATTGCTGGATTATTTGAAGTGGTATGGGCTACGATGATGAAATTAAGTAATGGGTTCAG
TCACTTTGGCTATGCTGCGGCCACAGTAGTTGGCATGGTCTTGAGTTTTGGCTTCTTAGCATTAGCAACCAAACACTTAC
CGTTGAGTATTGCATATCCAATTTGGACCGGTATCGGTGCGGTCGGTGCGATAATTGTTGGCCTGGTTTTCTTCAAAGAT
ACAATTGCACCCATCACGTGGATCTTCATTGCAATGCTGGTCATTGGCATTATTGGTATCAAAGTCACGAGTTAG

Upstream 100 bases:

>100_bases
ATTAAGATGAATTGTCACCGGACAACGTTAACCCAACTTCCTTAGGTCATTGTGGAAGTTGGGTGGACGTTGTCCTTTTT
ATTTTGAGGAGGAATTGATA

Downstream 100 bases:

>100_bases
GATTGGGGGGGTGTTAGTGGGTTTGTGATTCATCAGTGAAGCCCCAACAGCTTTTCAATATTTTTATAAAAGAATGACCA
CAAGCATGAAAGCGGTGTTA

Product: GroEL supressor protein SugE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 104; Mature: 103

Protein sequence:

>104_residues
MTWIYLIIAGLFEVVWATMMKLSNGFSHFGYAAATVVGMVLSFGFLALATKHLPLSIAYPIWTGIGAVGAIIVGLVFFKD
TIAPITWIFIAMLVIGIIGIKVTS

Sequences:

>Translated_104_residues
MTWIYLIIAGLFEVVWATMMKLSNGFSHFGYAAATVVGMVLSFGFLALATKHLPLSIAYPIWTGIGAVGAIIVGLVFFKD
TIAPITWIFIAMLVIGIIGIKVTS
>Mature_103_residues
TWIYLIIAGLFEVVWATMMKLSNGFSHFGYAAATVVGMVLSFGFLALATKHLPLSIAYPIWTGIGAVGAIIVGLVFFKDT
IAPITWIFIAMLVIGIIGIKVTS

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=104, Percent_Identity=47.1153846153846, Blast_Score=96, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11181; Mature: 11050

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTWIYLIIAGLFEVVWATMMKLSNGFSHFGYAAATVVGMVLSFGFLALATKHLPLSIAYP
CHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHH
IWTGIGAVGAIIVGLVFFKDTIAPITWIFIAMLVIGIIGIKVTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TWIYLIIAGLFEVVWATMMKLSNGFSHFGYAAATVVGMVLSFGFLALATKHLPLSIAYP
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHH
IWTGIGAVGAIIVGLVFFKDTIAPITWIFIAMLVIGIIGIKVTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]