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The map label for this gene is rbsK1 [H]

Identifier: 28377391

GI number: 28377391

Start: 447195

End: 448118

Strand: Direct

Name: rbsK1 [H]

Synonym: lp_0500

Alternate gene names: 28377391

Gene position: 447195-448118 (Clockwise)

Preceding gene: 28377390

Following gene: 28377392

Centisome position: 13.52

GC content: 44.05

Gene sequence:

>924_bases
ATGGCAGATGTTACAGTAATTGGCTCTAATATGATTGATTTGACAACTTATATTGGGCGGATGCCTGTCGAAGGCGAAAC
GATTGAGGCGCCAGAATTCAACATTGGCTACGGGGGTAAGGGTGCTAATCAAGCCATCGCGGCGGCACGCCTAGGTTCAG
ATGTTAATTTTATTACGATGGTTGGTAATGATGGGTTTGGACAAGAACAACTCGCTAATTATCAAAAAAATGGTATTCGT
ACGGATGGTATTGGCATTGGTCATCAAAATAGTGGGGTAGCCCCGATTTTCGTAGATCCAAGCAGTGATAACCGTATTTT
GATTATCAAGGGGGCTAACAAGGAACTGACTCCCGCTGTTTTGGATGAAAAACAGGCACTAATCAAGAATAGTAAACTAA
TTGTGTTGCAACAAGAAATCTCGCTAGAGACTAATTATCACGCCATTGATCTAGCACAACAATTTGGAGTGCCAGTTCTC
CTTAATCCAGCTCCTGCTAACAAGAATTTGAATATTGACTATGTCTCGAAGGTTGTGTTCTTTACGCCTAATGAAACAGA
ATTAGCTACGCTAACTGGGTTACCAACAAATAACCTGGATGAGATCAAGGTCGCGGCGTGTGATTTGATTAGTCGTGGCG
TTGAAAACCTGATTATTACGTTGGGTCATAAGGGCGCACTCTGGGTTACTGAAAACCATGCAGAAATCGTCCCAGGAATG
AAGGTTAAAGCCGTTGATACGACTGGCGCTGGGGATTCATTTATTGGTAGTTTTGCCCATTACTTTGCACAGGGTGAAGC
CATCCCGGACGCGTTGCAGCATGCGAACCAGTATGCAGCCATGACAGTGATGAAAAAGGGAACCCAAAAGTCATATCCGA
CGGCGGCAGAACTTTCAGATTTGTTAGCTGCTGCAGTGGATTAA

Upstream 100 bases:

>100_bases
AGCAGCTGCGACCAAAGCTGGAACGCTAATTATGTTGGAACCACAAGCAAAACGGCACTTTAGTGTGACGACCGGATTAG
AAAAGTAGGGGGACGACAAC

Downstream 100 bases:

>100_bases
ATGAATTGCAAGTGTTGTCATTATCTGACTAAAGCGCAGATAATTGGAACGCTTGCTTTCGCTTGTCCATCAAAAATTCG
CTATAAAAATCCTCAAAAGT

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MADVTVIGSNMIDLTTYIGRMPVEGETIEAPEFNIGYGGKGANQAIAAARLGSDVNFITMVGNDGFGQEQLANYQKNGIR
TDGIGIGHQNSGVAPIFVDPSSDNRILIIKGANKELTPAVLDEKQALIKNSKLIVLQQEISLETNYHAIDLAQQFGVPVL
LNPAPANKNLNIDYVSKVVFFTPNETELATLTGLPTNNLDEIKVAACDLISRGVENLIITLGHKGALWVTENHAEIVPGM
KVKAVDTTGAGDSFIGSFAHYFAQGEAIPDALQHANQYAAMTVMKKGTQKSYPTAAELSDLLAAAVD

Sequences:

>Translated_307_residues
MADVTVIGSNMIDLTTYIGRMPVEGETIEAPEFNIGYGGKGANQAIAAARLGSDVNFITMVGNDGFGQEQLANYQKNGIR
TDGIGIGHQNSGVAPIFVDPSSDNRILIIKGANKELTPAVLDEKQALIKNSKLIVLQQEISLETNYHAIDLAQQFGVPVL
LNPAPANKNLNIDYVSKVVFFTPNETELATLTGLPTNNLDEIKVAACDLISRGVENLIITLGHKGALWVTENHAEIVPGM
KVKAVDTTGAGDSFIGSFAHYFAQGEAIPDALQHANQYAAMTVMKKGTQKSYPTAAELSDLLAAAVD
>Mature_306_residues
ADVTVIGSNMIDLTTYIGRMPVEGETIEAPEFNIGYGGKGANQAIAAARLGSDVNFITMVGNDGFGQEQLANYQKNGIRT
DGIGIGHQNSGVAPIFVDPSSDNRILIIKGANKELTPAVLDEKQALIKNSKLIVLQQEISLETNYHAIDLAQQFGVPVLL
NPAPANKNLNIDYVSKVVFFTPNETELATLTGLPTNNLDEIKVAACDLISRGVENLIITLGHKGALWVTENHAEIVPGMK
VKAVDTTGAGDSFIGSFAHYFAQGEAIPDALQHANQYAAMTVMKKGTQKSYPTAAELSDLLAAAVD

Specific function: Ribose metabolism; first step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=299, Percent_Identity=40.133779264214, Blast_Score=195, Evalue=4e-50,
Organism=Escherichia coli, GI1790193, Length=301, Percent_Identity=35.5481727574751, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI87082343, Length=307, Percent_Identity=27.3615635179153, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788491, Length=290, Percent_Identity=23.7931034482759, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788484, Length=250, Percent_Identity=23.2, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=298, Percent_Identity=37.5838926174497, Blast_Score=193, Evalue=8e-50,
Organism=Saccharomyces cerevisiae, GI6319884, Length=326, Percent_Identity=29.7546012269939, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI20128807, Length=305, Percent_Identity=34.7540983606557, Blast_Score=163, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24583886, Length=302, Percent_Identity=28.8079470198675, Blast_Score=119, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 32680; Mature: 32549

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADVTVIGSNMIDLTTYIGRMPVEGETIEAPEFNIGYGGKGANQAIAAARLGSDVNFITM
CCCEEEECCCHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEE
VGNDGFGQEQLANYQKNGIRTDGIGIGHQNSGVAPIFVDPSSDNRILIIKGANKELTPAV
ECCCCCCHHHHHHHHHCCCEECCEECCCCCCCEEEEEECCCCCCEEEEEECCCCCCCHHH
LDEKQALIKNSKLIVLQQEISLETNYHAIDLAQQFGVPVLLNPAPANKNLNIDYVSKVVF
HHHHHHHHCCCEEEEEEEECCCCCCCEEEEHHHHCCCCEEECCCCCCCCCCCEEEEEEEE
FTPNETELATLTGLPTNNLDEIKVAACDLISRGVENLIITLGHKGALWVTENHAEIVPGM
ECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCHHHCCCC
KVKAVDTTGAGDSFIGSFAHYFAQGEAIPDALQHANQYAAMTVMKKGTQKSYPTAAELSD
EEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LLAAAVD
HHHHHCC
>Mature Secondary Structure 
ADVTVIGSNMIDLTTYIGRMPVEGETIEAPEFNIGYGGKGANQAIAAARLGSDVNFITM
CCEEEECCCHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEE
VGNDGFGQEQLANYQKNGIRTDGIGIGHQNSGVAPIFVDPSSDNRILIIKGANKELTPAV
ECCCCCCHHHHHHHHHCCCEECCEECCCCCCCEEEEEECCCCCCEEEEEECCCCCCCHHH
LDEKQALIKNSKLIVLQQEISLETNYHAIDLAQQFGVPVLLNPAPANKNLNIDYVSKVVF
HHHHHHHHCCCEEEEEEEECCCCCCCEEEEHHHHCCCCEEECCCCCCCCCCCEEEEEEEE
FTPNETELATLTGLPTNNLDEIKVAACDLISRGVENLIITLGHKGALWVTENHAEIVPGM
ECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCHHHCCCC
KVKAVDTTGAGDSFIGSFAHYFAQGEAIPDALQHANQYAAMTVMKKGTQKSYPTAAELSD
EEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LLAAAVD
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]