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The map label for this gene is gtmD [H]

Identifier: 28377380

GI number: 28377380

Start: 433608

End: 434927

Strand: Direct

Name: gtmD [H]

Synonym: lp_0486

Alternate gene names: 28377380

Gene position: 433608-434927 (Clockwise)

Preceding gene: 28377379

Following gene: 28377381

Centisome position: 13.11

GC content: 38.64

Gene sequence:

>1320_bases
ATGAAATCTGACTTTAATGACTTTTTCTTGGGAATGCCAGTTGAACATGCTGAGGATACAAATTTAGCTATTGACGGTGG
TAATCCAGTAATAACTAAACTAGGACGTCGAACCACATTTCCTAATATTACTAAAGAAGATGTTTTTCAATTAATGACCT
CAATTCAGGGTGAACCTGAAGCTGTAGTTAACGAATTTTGTGAAAAGTATCGAAAATATGTTGGTGCAAACTATGCAATT
GCCACTGCTAGCGGAACTTGTAGTTTACAGTTAGCCTTGATTGGTGCTGGTGTAAAGCCAGGCGATGAGGTGATTATTCC
TGCTTTCACGTTTATTGCAACTGCGCAAGCCGTGGTTGCTGCTAAAGCAATTCCGGTATTTGCAGATATTGATCCTGATA
CCTTCGATTTAGATCCGGCTGCTGTAGAAGCAAAGATTACGGACAAGACAGCAGCGATTATGCCAGTCCATGTACATGGA
CTACCTGCGGCAATGGATGAATTATCTGATATTTGTCAAAGACACCATCTGTTACTACTAGAAGATGCATCTCATGCGCA
TTCCGCAACATATCATGGAAAAATGTGTGGTTCAATCGGTGATGCAGCAGGACAGAGCCTAATGGCGGATAAAAATTTTC
CAGCAGGTGGGGAAGGCGGAATTGCTTTTTTTAAAACTGAAGAATCTTATCAACGAGCATTAAAGTTTTTGGATGATTCT
GGTCTTGATTTTAGAATGTCTTGGCTTGCAGCAGCGTTTGGAATTAGTCAATTGGATCGCCTGCCATATTATGATCAGAT
TAGACAACGTAATGCCCATCATTTAATTGCTTTTTTAAATAATGAAACGCGATTGTTTAATGGACCTTATATTCCGGATG
GCGAAAAGCATAGTTTCAATATGTTTCGAATTAAGTTGAATGTAGATTTACCTGAATTTAAGGGAATTGAAGATTACAAG
ATTAAACAAGTGGTACAAAATGCAGTACTGGAAGAAGGCGTCTTCGCACGGGAATGGCAAAATGTACCAATTCCGTGGCA
CCTACCTTTTAAAAATAAAATTGGCTTTGGACATTCCTATCCATTCAGCTTAGATGAAGGGACTCCAGATTATTCAAATA
CCAAGTACCCGAATGTATTAGATATGCTAAATACAACGCTGGTTTTATGTCGGGAATTACGCTCGCCAGTTGAATATGAA
AAGTTAAGTCATTATGAAGTCGCATTCAAAAAACTGGATAATCATATTGGGGAAATTGCTGAGATGGCTAAAGCTTTGAA
TGTTAAAAAACCATACGAAAGGGATGCTAGATTAGGTTGA

Upstream 100 bases:

>100_bases
AAACAGAATTAGATGTACAACCAGGTTTACAAATGAACTATCGATTAAGTCCATTAGTTGGAGCTTGCATAAAACTGTCA
ATTTTACGGAGGAATAAGTA

Downstream 100 bases:

>100_bases
AAAATAATATGAAAGTTGGAATCTTAGGTGGCTCTGGCTATGCTGGTGCAGAGCTGTACCGCTTGTTACTAAATCATCCG
AATTTTAACGTTACTTTTAT

Product: hypothetical protein

Products: TDP-D-fucosamine; 2-oxoglutarate [C]

Alternate protein names: Putative L-glutamine:amino-DOI aminotransferase; Putative gentamicin aminotransferase II [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MKSDFNDFFLGMPVEHAEDTNLAIDGGNPVITKLGRRTTFPNITKEDVFQLMTSIQGEPEAVVNEFCEKYRKYVGANYAI
ATASGTCSLQLALIGAGVKPGDEVIIPAFTFIATAQAVVAAKAIPVFADIDPDTFDLDPAAVEAKITDKTAAIMPVHVHG
LPAAMDELSDICQRHHLLLLEDASHAHSATYHGKMCGSIGDAAGQSLMADKNFPAGGEGGIAFFKTEESYQRALKFLDDS
GLDFRMSWLAAAFGISQLDRLPYYDQIRQRNAHHLIAFLNNETRLFNGPYIPDGEKHSFNMFRIKLNVDLPEFKGIEDYK
IKQVVQNAVLEEGVFAREWQNVPIPWHLPFKNKIGFGHSYPFSLDEGTPDYSNTKYPNVLDMLNTTLVLCRELRSPVEYE
KLSHYEVAFKKLDNHIGEIAEMAKALNVKKPYERDARLG

Sequences:

>Translated_439_residues
MKSDFNDFFLGMPVEHAEDTNLAIDGGNPVITKLGRRTTFPNITKEDVFQLMTSIQGEPEAVVNEFCEKYRKYVGANYAI
ATASGTCSLQLALIGAGVKPGDEVIIPAFTFIATAQAVVAAKAIPVFADIDPDTFDLDPAAVEAKITDKTAAIMPVHVHG
LPAAMDELSDICQRHHLLLLEDASHAHSATYHGKMCGSIGDAAGQSLMADKNFPAGGEGGIAFFKTEESYQRALKFLDDS
GLDFRMSWLAAAFGISQLDRLPYYDQIRQRNAHHLIAFLNNETRLFNGPYIPDGEKHSFNMFRIKLNVDLPEFKGIEDYK
IKQVVQNAVLEEGVFAREWQNVPIPWHLPFKNKIGFGHSYPFSLDEGTPDYSNTKYPNVLDMLNTTLVLCRELRSPVEYE
KLSHYEVAFKKLDNHIGEIAEMAKALNVKKPYERDARLG
>Mature_439_residues
MKSDFNDFFLGMPVEHAEDTNLAIDGGNPVITKLGRRTTFPNITKEDVFQLMTSIQGEPEAVVNEFCEKYRKYVGANYAI
ATASGTCSLQLALIGAGVKPGDEVIIPAFTFIATAQAVVAAKAIPVFADIDPDTFDLDPAAVEAKITDKTAAIMPVHVHG
LPAAMDELSDICQRHHLLLLEDASHAHSATYHGKMCGSIGDAAGQSLMADKNFPAGGEGGIAFFKTEESYQRALKFLDDS
GLDFRMSWLAAAFGISQLDRLPYYDQIRQRNAHHLIAFLNNETRLFNGPYIPDGEKHSFNMFRIKLNVDLPEFKGIEDYK
IKQVVQNAVLEEGVFAREWQNVPIPWHLPFKNKIGFGHSYPFSLDEGTPDYSNTKYPNVLDMLNTTLVLCRELRSPVEYE
KLSHYEVAFKKLDNHIGEIAEMAKALNVKKPYERDARLG

Specific function: Catalyzes the transamination of 3-amino-2,3-dideoxy- scyllo-inosose (amino-DOI) into 2-deoxystreptamine (DOS) (Potential) [H]

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family. L-glutamine:2- deoxy-scyllo-inosose/scyllo-inosose aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI2367285, Length=264, Percent_Identity=34.0909090909091, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI145693159, Length=193, Percent_Identity=34.7150259067358, Blast_Score=110, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01041 DegT_DnrJ_EryC1 [H]

EC number: NA

Molecular weight: Translated: 48837; Mature: 48837

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSDFNDFFLGMPVEHAEDTNLAIDGGNPVITKLGRRTTFPNITKEDVFQLMTSIQGEPE
CCCCCCCCEECCCCCCCCCCEEEEECCCHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHH
AVVNEFCEKYRKYVGANYAIATASGTCSLQLALIGAGVKPGDEVIIPAFTFIATAQAVVA
HHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEEEECCCCCCCCEEEHHHHHHHHHHHHHH
AKAIPVFADIDPDTFDLDPAAVEAKITDKTAAIMPVHVHGLPAAMDELSDICQRHHLLLL
HHHCEEEECCCCCCCCCCHHHEEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHCCEEEE
EDASHAHSATYHGKMCGSIGDAAGQSLMADKNFPAGGEGGIAFFKTEESYQRALKFLDDS
ECCCCCCCCCCCCHHHCCHHHHHCCHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHHCCC
GLDFRMSWLAAAFGISQLDRLPYYDQIRQRNAHHLIAFLNNETRLFNGPYIPDGEKHSFN
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEECCCCEEECCCCCCCCCCCCEE
MFRIKLNVDLPEFKGIEDYKIKQVVQNAVLEEGVFAREWQNVPIPWHLPFKNKIGFGHSY
EEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCEECCCCCCCCCCCCC
PFSLDEGTPDYSNTKYPNVLDMLNTTLVLCRELRSPVEYEKLSHYEVAFKKLDNHIGEIA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
EMAKALNVKKPYERDARLG
HHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKSDFNDFFLGMPVEHAEDTNLAIDGGNPVITKLGRRTTFPNITKEDVFQLMTSIQGEPE
CCCCCCCCEECCCCCCCCCCEEEEECCCHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHH
AVVNEFCEKYRKYVGANYAIATASGTCSLQLALIGAGVKPGDEVIIPAFTFIATAQAVVA
HHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEEEECCCCCCCCEEEHHHHHHHHHHHHHH
AKAIPVFADIDPDTFDLDPAAVEAKITDKTAAIMPVHVHGLPAAMDELSDICQRHHLLLL
HHHCEEEECCCCCCCCCCHHHEEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHCCEEEE
EDASHAHSATYHGKMCGSIGDAAGQSLMADKNFPAGGEGGIAFFKTEESYQRALKFLDDS
ECCCCCCCCCCCCHHHCCHHHHHCCHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHHCCC
GLDFRMSWLAAAFGISQLDRLPYYDQIRQRNAHHLIAFLNNETRLFNGPYIPDGEKHSFN
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEECCCCEEECCCCCCCCCCCCEE
MFRIKLNVDLPEFKGIEDYKIKQVVQNAVLEEGVFAREWQNVPIPWHLPFKNKIGFGHSY
EEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCEECCCCCCCCCCCCC
PFSLDEGTPDYSNTKYPNVLDMLNTTLVLCRELRSPVEYEKLSHYEVAFKKLDNHIGEIA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
EMAKALNVKKPYERDARLG
HHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dTDP-4-dehydro-6-deoxy-D-glucose; L-glutamate [C]

Specific reaction: dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate = TDP-D-fucosamine + 2-oxoglutarate [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA