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The map label for this gene is yabD [H]

Identifier: 28377356

GI number: 28377356

Start: 410280

End: 411056

Strand: Direct

Name: yabD [H]

Synonym: lp_0456

Alternate gene names: 28377356

Gene position: 410280-411056 (Clockwise)

Preceding gene: 28377355

Following gene: 28377357

Centisome position: 12.4

GC content: 46.33

Gene sequence:

>777_bases
ATGCGGATTTTTGATTCTCATACCCATTTAAATAGTGAAGAATTCATCCAGGAAGTGCCACGTTACTTACAACAAGCGGC
TGACCTTGATGTTACGCGGATGGCAATCGTTGGTTCGAATACACAACTGAACGCCGATGCGATTAAACTGGCGGAAACGT
ATCCTCAGTTAGTCGCGATTGTTGGTTGGCACCCGGAAGATGCCAAAAACTATGATCAGGCGGCTGAAAAGTTGTTGATT
GAACAAGTCCAACACCCGAAAGTCGTCGCGTTAGGTGAGATTGGACTGGACTACCATTGGGATACGTCGCCACAAGACGT
TCAGCGGCAAGTCTTTGCCCGCCAAGTCGCCATTGCTAAAGAGATGCAATTGCCAATTTCCGTGCACAATCGTGATGCTT
TCGAAGATACCTATAAGATCTTGAAAGCAGCTGATATTCGTGACACGGGTGGCGTCATGCATAGCTTTAATGGTGACCCT
GAGTGGCTCAAACGGTTCTTGGACTTAGGTATGCATATTTCCTATAGTGGTGTCGCATCATTTAAGAATGCGCGTGAAGT
CCATGAATCCGTCAAGCAAACGCCACTAACGCAAATGCTGGTTGAAACGGATGCCCCTTATCTAACGCCGGAACCATACC
GGGGAAAGCAGAACGAACCCGGTTACACGCGGTACGTTGTTGAAGCAATTGCCAAGTTACGTGAAACGACGCCGGAAATT
ATAGCGGCCCAAACTTATCAAAATGCAGAGGAATTTTTTAAGATTGAAAAAGATTAA

Upstream 100 bases:

>100_bases
ACCCAGGCTTTTTGTTTTAGAATTACCGTCTTCTTTTCCGAAAACTTGCGTCCCATGGTAAAATCAACTAAGATAACAAA
AGTCGAAAAGGGGTTATTAC

Downstream 100 bases:

>100_bases
AGAAGTAATTGTGGTTGAAGGGAAAGATGACACGAAGCGTCTCGCCCTAGCTGTCGATGCAGATACACTTGAAACGAATG
GCTCGGCGATTTCCGAAGCC

Product: DNAse (putative)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MRIFDSHTHLNSEEFIQEVPRYLQQAADLDVTRMAIVGSNTQLNADAIKLAETYPQLVAIVGWHPEDAKNYDQAAEKLLI
EQVQHPKVVALGEIGLDYHWDTSPQDVQRQVFARQVAIAKEMQLPISVHNRDAFEDTYKILKAADIRDTGGVMHSFNGDP
EWLKRFLDLGMHISYSGVASFKNAREVHESVKQTPLTQMLVETDAPYLTPEPYRGKQNEPGYTRYVVEAIAKLRETTPEI
IAAQTYQNAEEFFKIEKD

Sequences:

>Translated_258_residues
MRIFDSHTHLNSEEFIQEVPRYLQQAADLDVTRMAIVGSNTQLNADAIKLAETYPQLVAIVGWHPEDAKNYDQAAEKLLI
EQVQHPKVVALGEIGLDYHWDTSPQDVQRQVFARQVAIAKEMQLPISVHNRDAFEDTYKILKAADIRDTGGVMHSFNGDP
EWLKRFLDLGMHISYSGVASFKNAREVHESVKQTPLTQMLVETDAPYLTPEPYRGKQNEPGYTRYVVEAIAKLRETTPEI
IAAQTYQNAEEFFKIEKD
>Mature_258_residues
MRIFDSHTHLNSEEFIQEVPRYLQQAADLDVTRMAIVGSNTQLNADAIKLAETYPQLVAIVGWHPEDAKNYDQAAEKLLI
EQVQHPKVVALGEIGLDYHWDTSPQDVQRQVFARQVAIAKEMQLPISVHNRDAFEDTYKILKAADIRDTGGVMHSFNGDP
EWLKRFLDLGMHISYSGVASFKNAREVHESVKQTPLTQMLVETDAPYLTPEPYRGKQNEPGYTRYVVEAIAKLRETTPEI
IAAQTYQNAEEFFKIEKD

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=260, Percent_Identity=27.6923076923077, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI225903439, Length=247, Percent_Identity=28.3400809716599, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI225903424, Length=200, Percent_Identity=32, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI110349730, Length=264, Percent_Identity=28.4090909090909, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI226061853, Length=272, Percent_Identity=28.6764705882353, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI110349734, Length=264, Percent_Identity=28.030303030303, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI226061614, Length=253, Percent_Identity=27.6679841897233, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI226061595, Length=230, Percent_Identity=28.695652173913, Blast_Score=78, Evalue=9e-15,
Organism=Escherichia coli, GI1787342, Length=261, Percent_Identity=36.0153256704981, Blast_Score=160, Evalue=7e-41,
Organism=Escherichia coli, GI48994985, Length=259, Percent_Identity=31.6602316602317, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI87082439, Length=257, Percent_Identity=30.3501945525292, Blast_Score=118, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17559024, Length=281, Percent_Identity=28.8256227758007, Blast_Score=134, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI71980746, Length=262, Percent_Identity=28.2442748091603, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17543026, Length=215, Percent_Identity=26.9767441860465, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17565396, Length=218, Percent_Identity=26.605504587156, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24648690, Length=285, Percent_Identity=27.3684210526316, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24586117, Length=246, Percent_Identity=29.6747967479675, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI221330018, Length=246, Percent_Identity=29.6747967479675, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29415; Mature: 29415

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIFDSHTHLNSEEFIQEVPRYLQQAADLDVTRMAIVGSNTQLNADAIKLAETYPQLVAI
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHEEEEECCCCCCCHHHHHHHHHHHHHHHH
VGWHPEDAKNYDQAAEKLLIEQVQHPKVVALGEIGLDYHWDTSPQDVQRQVFARQVAIAK
CCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
EMQLPISVHNRDAFEDTYKILKAADIRDTGGVMHSFNGDPEWLKRFLDLGMHISYSGVAS
HHCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHH
FKNAREVHESVKQTPLTQMLVETDAPYLTPEPYRGKQNEPGYTRYVVEAIAKLRETTPEI
HHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHH
IAAQTYQNAEEFFKIEKD
HHHHHHHCHHHHHCCCCC
>Mature Secondary Structure
MRIFDSHTHLNSEEFIQEVPRYLQQAADLDVTRMAIVGSNTQLNADAIKLAETYPQLVAI
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHEEEEECCCCCCCHHHHHHHHHHHHHHHH
VGWHPEDAKNYDQAAEKLLIEQVQHPKVVALGEIGLDYHWDTSPQDVQRQVFARQVAIAK
CCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
EMQLPISVHNRDAFEDTYKILKAADIRDTGGVMHSFNGDPEWLKRFLDLGMHISYSGVAS
HHCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHH
FKNAREVHESVKQTPLTQMLVETDAPYLTPEPYRGKQNEPGYTRYVVEAIAKLRETTPEI
HHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHH
IAAQTYQNAEEFFKIEKD
HHHHHHHCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]