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The map label for this gene is ydhC [C]

Identifier: 28377355

GI number: 28377355

Start: 408973

End: 410157

Strand: Direct

Name: ydhC [C]

Synonym: lp_0455

Alternate gene names: 28377355

Gene position: 408973-410157 (Clockwise)

Preceding gene: 28377354

Following gene: 28377356

Centisome position: 12.36

GC content: 48.86

Gene sequence:

>1185_bases
ATGAAAAACGTCCAAAAACAAGTGCCATCATTATTACTGTTAATCACATTAGTGGGTTTTCCACAAATCAGTGAATCAAT
TTTTACGCCGATCTTGCCAGCACTCAGTCAGGCAATGCACGTTAGCGCCAGCCACAGCCAGATAACCATGAGCAGTTACT
TTGTGGCTTTTGCAGTTGGGGTGCTCTTCTGGGGGCAATATGCTGACTATCGCGGGCGCCGTGATGCCATGTTAGGTGGA
TTAGCCTTTTATTTGATTGGTAACTTAGGGTTATATCTGAGCCCGGGCTTTACTTGGTTATTGGTTTGCCGCTTGATCCA
AGCTTTCGGTGCTAGTGCTGGTTCGGTTGTGACACAGACTATCATGCGTGAGAGCTTTACGGGTGTTACTGGTGCAAAAA
TCTTTGCGAAGGTGAGTGCGGCCATGGCACTATCACCCGCTCTCGGGCCACTCATCGGAGGTGGCGTCCAGACTGTGTTC
GGCTATCAGCATGTCTTCTCGGTCTTGATCATGATAGCAGTCGTAATACTGTTGTACGCGGGGTGTTGCTTGCCAGAGAC
TCGACCAGAAACGGTCAAAGTGGCCTCTTGGCGGCAACAAAGCGTTGTCGTTTCACGGTTATTGCACGATCCCGTGGTCT
GGTGTTACGGCCTATTGATTAGTGGTATTAATGGTATCTTGTTTAGTTATTACGCTGAAGCGCCGTTTATTTTTGAAACG
CACTTCGGCTTTAGTGCTGTGCAATACGGTAGTCTCGGTTTAGTCTTAGCCGCGGCCAGTCTGCTGGGCGCGTTGCTAGT
GAATTGGCTTGTCAACTATTGGTCACCAATGCAGGTCGCTTTAAGTGGCTTAGGATTGAGTTTGGTAGCGGCAGTTGGCT
TGGTGATGACCGCTGTTGGCAATCACGTCATTGGGATGCTGATTGGGATTTTTCTAGCCTTCTTAGGTCTGAACATCACC
CTACCAAACGCGTTGAATCGTGCTTTGATTGGCTATGAAACGGTGATGGGGAGTGCCAGTGGCTGGTTTAGCCTGGGTTA
TTATCTACTAGTGAGTGTGCTAACTTACTTAATGAGTTGGCTCCACCACGGTAGTATCGTGACATTGCCCGTATACATGT
TAGGCGTGGTCGTCGTGATGACGGTGGTGTATGCGGGACTGTATTGGCGGCGTGTACGTCATTAA

Upstream 100 bases:

>100_bases
GGTGAGAACATATGAAGTATGAACAGATTCTCGTATGCGTCTCCGTAGATGGAAAAGGACGTTTTTCCGAAAATTAATTA
AATTTAGGAGACTTAATTAA

Downstream 100 bases:

>100_bases
TTTTGCTTGAAAGCTTGGGGAAACCCAGGCTTTTTGTTTTAGAATTACCGTCTTCTTTTCCGAAAACTTGCGTCCCATGG
TAAAATCAACTAAGATAACA

Product: transport protein

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MKNVQKQVPSLLLLITLVGFPQISESIFTPILPALSQAMHVSASHSQITMSSYFVAFAVGVLFWGQYADYRGRRDAMLGG
LAFYLIGNLGLYLSPGFTWLLVCRLIQAFGASAGSVVTQTIMRESFTGVTGAKIFAKVSAAMALSPALGPLIGGGVQTVF
GYQHVFSVLIMIAVVILLYAGCCLPETRPETVKVASWRQQSVVVSRLLHDPVVWCYGLLISGINGILFSYYAEAPFIFET
HFGFSAVQYGSLGLVLAAASLLGALLVNWLVNYWSPMQVALSGLGLSLVAAVGLVMTAVGNHVIGMLIGIFLAFLGLNIT
LPNALNRALIGYETVMGSASGWFSLGYYLLVSVLTYLMSWLHHGSIVTLPVYMLGVVVVMTVVYAGLYWRRVRH

Sequences:

>Translated_394_residues
MKNVQKQVPSLLLLITLVGFPQISESIFTPILPALSQAMHVSASHSQITMSSYFVAFAVGVLFWGQYADYRGRRDAMLGG
LAFYLIGNLGLYLSPGFTWLLVCRLIQAFGASAGSVVTQTIMRESFTGVTGAKIFAKVSAAMALSPALGPLIGGGVQTVF
GYQHVFSVLIMIAVVILLYAGCCLPETRPETVKVASWRQQSVVVSRLLHDPVVWCYGLLISGINGILFSYYAEAPFIFET
HFGFSAVQYGSLGLVLAAASLLGALLVNWLVNYWSPMQVALSGLGLSLVAAVGLVMTAVGNHVIGMLIGIFLAFLGLNIT
LPNALNRALIGYETVMGSASGWFSLGYYLLVSVLTYLMSWLHHGSIVTLPVYMLGVVVVMTVVYAGLYWRRVRH
>Mature_394_residues
MKNVQKQVPSLLLLITLVGFPQISESIFTPILPALSQAMHVSASHSQITMSSYFVAFAVGVLFWGQYADYRGRRDAMLGG
LAFYLIGNLGLYLSPGFTWLLVCRLIQAFGASAGSVVTQTIMRESFTGVTGAKIFAKVSAAMALSPALGPLIGGGVQTVF
GYQHVFSVLIMIAVVILLYAGCCLPETRPETVKVASWRQQSVVVSRLLHDPVVWCYGLLISGINGILFSYYAEAPFIFET
HFGFSAVQYGSLGLVLAAASLLGALLVNWLVNYWSPMQVALSGLGLSLVAAVGLVMTAVGNHVIGMLIGIFLAFLGLNIT
LPNALNRALIGYETVMGSASGWFSLGYYLLVSVLTYLMSWLHHGSIVTLPVYMLGVVVVMTVVYAGLYWRRVRH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=236, Percent_Identity=26.6949152542373, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1790146, Length=312, Percent_Identity=22.7564102564103, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1788509, Length=221, Percent_Identity=25.7918552036199, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87082312, Length=168, Percent_Identity=24.4047619047619, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42526; Mature: 42526

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNVQKQVPSLLLLITLVGFPQISESIFTPILPALSQAMHVSASHSQITMSSYFVAFAVG
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VLFWGQYADYRGRRDAMLGGLAFYLIGNLGLYLSPGFTWLLVCRLIQAFGASAGSVVTQT
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHCCCCHHHHHHH
IMRESFTGVTGAKIFAKVSAAMALSPALGPLIGGGVQTVFGYQHVFSVLIMIAVVILLYA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GCCLPETRPETVKVASWRQQSVVVSRLLHDPVVWCYGLLISGINGILFSYYAEAPFIFET
CCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
HFGFSAVQYGSLGLVLAAASLLGALLVNWLVNYWSPMQVALSGLGLSLVAAVGLVMTAVG
CCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHH
NHVIGMLIGIFLAFLGLNITLPNALNRALIGYETVMGSASGWFSLGYYLLVSVLTYLMSW
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LHHGSIVTLPVYMLGVVVVMTVVYAGLYWRRVRH
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA