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The map label for this gene is bglK [H]

Identifier: 28377343

GI number: 28377343

Start: 395150

End: 396046

Strand: Direct

Name: bglK [H]

Synonym: lp_0441

Alternate gene names: 28377343

Gene position: 395150-396046 (Clockwise)

Preceding gene: 28377342

Following gene: 28377344

Centisome position: 11.94

GC content: 44.26

Gene sequence:

>897_bases
ATGACAATGTATATTGGAATTGATATTGGTGGTACTTCAATCAAGTGCGGCCTAGTTGATGCTCATGGACATATTAGTCG
TAAAGTAACACGACCGACTGCCACAGCAAAGGTAGACATTATGGCCGATTTAGTTGCGATGATTCAAGGACTACAAGCAG
ATGGACAAGTTGCTGGTATTGGAGTTAGCATGCCGGGAGTTGTTCAAAGTGACGGCTTCTTGACGACGGCAGGTGCGGTC
ACGGCGTTTGAAAAAATTAACTTGCAAGCTGAGTTACATGCACAGACGCAGTTACCGGTCATTATTGAAAATGATGCCAA
CGCAGCGGCTATTGCTGAGCAATGGCTGGGAGTAGCTCAGAATGTGCCTAATTATTTAAGCTTGGTTCTTGGAACCGGGG
TCGGTGGGGCACTGGTTATCAATAATCAGATTTATCGGGGTGCACACGCGCGTTCAGGCGAATTTGGTTGGATGGTTGTT
GACGATGATGAGATTGATACTGAAATGGGAACCCTTAATTTCCGGGGTGCAACAGTTATCGGTCTCATACGACGTTATAA
TCAGTTTAGTGCGATGCCGGTTACTGACGCGCGCGAGATTTTTGACCGAGCAGATGCGGGAGAAGTACTGGCACAACATG
TCTTTCATAGCTACTATTACAGTTTGGCTAAAGGAATCATTAATTTAATGGTTGCTTTTGATCCCGAATTAGTCGTAATT
GGTGGTGGCATTAGTGCGAACATGACCTTTATGACTGATTTGAATGCAACGATTGCAGACTTACAGGCTAATCATAATAG
TATTAATCATTTGACTTTGGCATCAGTAGTACCAGCTAAATTGCGGAATGATGCTGGGATGATTGGGGCAGTGTATCAGT
TGATTAAGCGTGGTTAA

Upstream 100 bases:

>100_bases
GGTCATTAATTATTGACTAGTGCTTAATTAATGATGTTTGAAATAGTTGTCAATGGCCAGCTTTGATAGCTGGCCATTGG
GCGTTTAGGAGGACTGTTAA

Downstream 100 bases:

>100_bases
AAAGGCGGATCAAACTGGTTTATTAAAATAGGGTGACACGTATTTTAATTTAAAAAATGAAAAAGCTTGAATGCTAGATG
TTTTTTAGAAGCGGTTACGC

Product: sugar kinase and transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MTMYIGIDIGGTSIKCGLVDAHGHISRKVTRPTATAKVDIMADLVAMIQGLQADGQVAGIGVSMPGVVQSDGFLTTAGAV
TAFEKINLQAELHAQTQLPVIIENDANAAAIAEQWLGVAQNVPNYLSLVLGTGVGGALVINNQIYRGAHARSGEFGWMVV
DDDEIDTEMGTLNFRGATVIGLIRRYNQFSAMPVTDAREIFDRADAGEVLAQHVFHSYYYSLAKGIINLMVAFDPELVVI
GGGISANMTFMTDLNATIADLQANHNSINHLTLASVVPAKLRNDAGMIGAVYQLIKRG

Sequences:

>Translated_298_residues
MTMYIGIDIGGTSIKCGLVDAHGHISRKVTRPTATAKVDIMADLVAMIQGLQADGQVAGIGVSMPGVVQSDGFLTTAGAV
TAFEKINLQAELHAQTQLPVIIENDANAAAIAEQWLGVAQNVPNYLSLVLGTGVGGALVINNQIYRGAHARSGEFGWMVV
DDDEIDTEMGTLNFRGATVIGLIRRYNQFSAMPVTDAREIFDRADAGEVLAQHVFHSYYYSLAKGIINLMVAFDPELVVI
GGGISANMTFMTDLNATIADLQANHNSINHLTLASVVPAKLRNDAGMIGAVYQLIKRG
>Mature_297_residues
TMYIGIDIGGTSIKCGLVDAHGHISRKVTRPTATAKVDIMADLVAMIQGLQADGQVAGIGVSMPGVVQSDGFLTTAGAVT
AFEKINLQAELHAQTQLPVIIENDANAAAIAEQWLGVAQNVPNYLSLVLGTGVGGALVINNQIYRGAHARSGEFGWMVVD
DDEIDTEMGTLNFRGATVIGLIRRYNQFSAMPVTDAREIFDRADAGEVLAQHVFHSYYYSLAKGIINLMVAFDPELVVIG
GGISANMTFMTDLNATIADLQANHNSINHLTLASVVPAKLRNDAGMIGAVYQLIKRG

Specific function: Catalyzes the ATP-dependent phosphorylation of cellobiose to produce cellobiose-6'-P. May have a dual role of kinase and transcriptional regulator of the cellobiose-PTS operon [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=265, Percent_Identity=23.7735849056604, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI298566315, Length=265, Percent_Identity=23.7735849056604, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI4885285, Length=265, Percent_Identity=23.7735849056604, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI190014632, Length=265, Percent_Identity=23.7735849056604, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1787363, Length=309, Percent_Identity=30.42071197411, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI87081733, Length=260, Percent_Identity=26.5384615384615, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.85 [H]

Molecular weight: Translated: 31671; Mature: 31540

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMYIGIDIGGTSIKCGLVDAHGHISRKVTRPTATAKVDIMADLVAMIQGLQADGQVAGI
CEEEEEEEECCCEEEEEEEECCCCCHHEEECCCCHHHHHHHHHHHHHHHCCCCCCCEEEE
GVSMPGVVQSDGFLTTAGAVTAFEKINLQAELHAQTQLPVIIENDANAAAIAEQWLGVAQ
EECCCCCEECCCEEEECHHHHHHHHHCCEEEEEECCCCCEEEECCCCHHHHHHHHHHHHH
NVPNYLSLVLGTGVGGALVINNQIYRGAHARSGEFGWMVVDDDEIDTEMGTLNFRGATVI
CCHHHHHHHHHCCCCCEEEECCCEECCCCCCCCCEEEEEEECCCCCCCCCEEEECCHHHH
GLIRRYNQFSAMPVTDAREIFDRADAGEVLAQHVFHSYYYSLAKGIINLMVAFDPELVVI
HHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEE
GGGISANMTFMTDLNATIADLQANHNSINHLTLASVVPAKLRNDAGMIGAVYQLIKRG
ECCCCCCEEEEEECCCCEEHHHCCCCCCCEEEHHHHHHHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TMYIGIDIGGTSIKCGLVDAHGHISRKVTRPTATAKVDIMADLVAMIQGLQADGQVAGI
EEEEEEEECCCEEEEEEEECCCCCHHEEECCCCHHHHHHHHHHHHHHHCCCCCCCEEEE
GVSMPGVVQSDGFLTTAGAVTAFEKINLQAELHAQTQLPVIIENDANAAAIAEQWLGVAQ
EECCCCCEECCCEEEECHHHHHHHHHCCEEEEEECCCCCEEEECCCCHHHHHHHHHHHHH
NVPNYLSLVLGTGVGGALVINNQIYRGAHARSGEFGWMVVDDDEIDTEMGTLNFRGATVI
CCHHHHHHHHHCCCCCEEEECCCEECCCCCCCCCEEEEEEECCCCCCCCCEEEECCHHHH
GLIRRYNQFSAMPVTDAREIFDRADAGEVLAQHVFHSYYYSLAKGIINLMVAFDPELVVI
HHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEE
GGGISANMTFMTDLNATIADLQANHNSINHLTLASVVPAKLRNDAGMIGAVYQLIKRG
ECCCCCCEEEEEECCCCEEHHHCCCCCCCEEEHHHHHHHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669; 12110692 [H]