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The map label for this gene is glpD [H]

Identifier: 28377286

GI number: 28377286

Start: 340417

End: 342246

Strand: Direct

Name: glpD [H]

Synonym: lp_0371

Alternate gene names: 28377286

Gene position: 340417-342246 (Clockwise)

Preceding gene: 28377285

Following gene: 28377287

Centisome position: 10.29

GC content: 46.89

Gene sequence:

>1830_bases
ATGGCATTTTCAGCAACGACGCGTCAACAAAATATTGAACGCTTACAAAATGAAACGTTAGATTTACTCGTTATCGGTGG
TGGGATTACCGGTGCCGGTGTCGCCATTCAATCAACTGCAATGAACATGAAGACCGGGTTGATCGATATGCAAGACTTTG
CAGAAGGGACTTCATCACGGTCGACGAAACTGGTCCATGGGGGTATTCGTTACTTAAAGACGTTTGACGTGGGGGTAGTC
GCCGATACCGTTAAAGAACGGGCGGTCGTCCAGGGGATTGCGCCACACATTCCTAAGCCCGACCCAATGTTATTGCCGAT
TTATGATGAGACGGGAGCGACCTTCGACCTCTTTTCTGTCAAAGTGGCGATGGATCTGTATGATAAGCTCGCCGAAGTTA
AAGATCCTAAATTCACCAATTATACCCTTTCGCGCGAGGAAGTCTTACAACGGGAACCACAGCTGAACCCTAAACATTTA
GTTGGTGGCGGTGTTTACCTTGATTTTCGGAATAATGATGCGCGCCTAGTGATTGAAAACATTAAGAAGGCTCACGAAAA
TGGTGGGATTATGGCAAGTCATGTGAAGGCGACCGGCCTCTTACATGATGATGATGGCCGGATCAATGGTATCACCGCTG
AAGACTTATTGACTGGTGCATCGTTCGAGATTCATGCCCGAATCGTCATCAATACGACCGGTCCATGGTCAGACACGATT
CGTAAGATGGACCATACTGAAAAGTATCAATCCCAGATGCGGCCAACCAAGGGTGTACATTTAGTCGTTGACGCTGAGAA
ACTCCCAGTGCCACAACCAACCTATTTTGATTCTGGTGATCAAGATGGCCGGATGATCTTCGTGGTGCCACGTGAAAACA
AGACGTATTTCGGAACGACTGATACGGATTATCATGGTGATCTGAAACACCCGACCGTTACGCAAGAAGATGTTGATTAC
TTGTTGGAAATCGTCAACCGTCGCTTTCCAACTGCTAAAATCACCTTAGATGATATTGAGGCTAGTTGGGCCGGATTGCG
GCCACTGATCGCCGCTAACGGTAGTTCTGATTATAACGGTGGTAATTCAGGAAAAATCAGTGATAAGAGCTTCAAGGAAG
TTATCAAGGTTGTTGATCAGTTTGAAAGTCAGGAAGCCAGTCGTGAAGATGTCGAAAGTGTCCTGAATGACTTGGAAACT
TCCTTGGCAGAGGACAAACTCAGTCCGTCAGCGGTTTCACGCGGTAGTTCGTTGACTAGTAGTCCAGACGGGCTGTTGAC
CCTTGCTGGTGGGAAGATTACTGATTACCGTAAAATGGCTGCGGGTGCCATGGCGCTGATTGCCAAGATTTTAGCAGATA
AGTATGATGCCCACTTTAATGAAATCAATTCGAAGAACCTCCCCGTTTCTGGTGGCGATATTGATCCGCACAACGTGGAT
GCAACGATTGCATTTTATGCTAAACAAGGGACGGATAATGGTTTGACGAATGATGAAGCGTTGCGGATTGCAAATATGTA
CGGTTCCAATGCTGCGCGGGTCTTTAGTTTGATTGGTAAAGTTGAACCGACGCATGGTCTGAGCTTAGCTGAAACGATTA
GCTTACGTTATGCCTTGGATGAAGAAATGACCCTGACGCCAGTCGACTACTTGCTGCGGCGCACTAACCACTTGTTATTC
ATGCGAGATACGCTGGATGGCTTAAAGGATGGCGTCATAGCGACAATGGCCGATTATCTTGGTTGGGATGCTGCAACGGT
CAAAGCACAAACCGAATTATTGAATCAGACGATTGCTGAATCGGACTTAACAGCACTGAAGCAGGGCTAA

Upstream 100 bases:

>100_bases
AACGGACGAACTTATACGAGGGATGGCAGGCAGCGGTCAAAGCGACCCAAGTCTTTAAGCACACCCCATACCACGCAGGA
AAATAGAGGAGGACAACAAC

Downstream 100 bases:

>100_bases
GGAATGGGGTGGTCATGATGAAAGATCCATTAGCACTACAATTGTTGGGGGAATTTCTCGGGACCTTTATCTTGATTCTG
TTAGGTGATGGGGTTGTAGC

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: Glycerol-3-phosphate oxidase [H]

Number of amino acids: Translated: 609; Mature: 608

Protein sequence:

>609_residues
MAFSATTRQQNIERLQNETLDLLVIGGGITGAGVAIQSTAMNMKTGLIDMQDFAEGTSSRSTKLVHGGIRYLKTFDVGVV
ADTVKERAVVQGIAPHIPKPDPMLLPIYDETGATFDLFSVKVAMDLYDKLAEVKDPKFTNYTLSREEVLQREPQLNPKHL
VGGGVYLDFRNNDARLVIENIKKAHENGGIMASHVKATGLLHDDDGRINGITAEDLLTGASFEIHARIVINTTGPWSDTI
RKMDHTEKYQSQMRPTKGVHLVVDAEKLPVPQPTYFDSGDQDGRMIFVVPRENKTYFGTTDTDYHGDLKHPTVTQEDVDY
LLEIVNRRFPTAKITLDDIEASWAGLRPLIAANGSSDYNGGNSGKISDKSFKEVIKVVDQFESQEASREDVESVLNDLET
SLAEDKLSPSAVSRGSSLTSSPDGLLTLAGGKITDYRKMAAGAMALIAKILADKYDAHFNEINSKNLPVSGGDIDPHNVD
ATIAFYAKQGTDNGLTNDEALRIANMYGSNAARVFSLIGKVEPTHGLSLAETISLRYALDEEMTLTPVDYLLRRTNHLLF
MRDTLDGLKDGVIATMADYLGWDAATVKAQTELLNQTIAESDLTALKQG

Sequences:

>Translated_609_residues
MAFSATTRQQNIERLQNETLDLLVIGGGITGAGVAIQSTAMNMKTGLIDMQDFAEGTSSRSTKLVHGGIRYLKTFDVGVV
ADTVKERAVVQGIAPHIPKPDPMLLPIYDETGATFDLFSVKVAMDLYDKLAEVKDPKFTNYTLSREEVLQREPQLNPKHL
VGGGVYLDFRNNDARLVIENIKKAHENGGIMASHVKATGLLHDDDGRINGITAEDLLTGASFEIHARIVINTTGPWSDTI
RKMDHTEKYQSQMRPTKGVHLVVDAEKLPVPQPTYFDSGDQDGRMIFVVPRENKTYFGTTDTDYHGDLKHPTVTQEDVDY
LLEIVNRRFPTAKITLDDIEASWAGLRPLIAANGSSDYNGGNSGKISDKSFKEVIKVVDQFESQEASREDVESVLNDLET
SLAEDKLSPSAVSRGSSLTSSPDGLLTLAGGKITDYRKMAAGAMALIAKILADKYDAHFNEINSKNLPVSGGDIDPHNVD
ATIAFYAKQGTDNGLTNDEALRIANMYGSNAARVFSLIGKVEPTHGLSLAETISLRYALDEEMTLTPVDYLLRRTNHLLF
MRDTLDGLKDGVIATMADYLGWDAATVKAQTELLNQTIAESDLTALKQG
>Mature_608_residues
AFSATTRQQNIERLQNETLDLLVIGGGITGAGVAIQSTAMNMKTGLIDMQDFAEGTSSRSTKLVHGGIRYLKTFDVGVVA
DTVKERAVVQGIAPHIPKPDPMLLPIYDETGATFDLFSVKVAMDLYDKLAEVKDPKFTNYTLSREEVLQREPQLNPKHLV
GGGVYLDFRNNDARLVIENIKKAHENGGIMASHVKATGLLHDDDGRINGITAEDLLTGASFEIHARIVINTTGPWSDTIR
KMDHTEKYQSQMRPTKGVHLVVDAEKLPVPQPTYFDSGDQDGRMIFVVPRENKTYFGTTDTDYHGDLKHPTVTQEDVDYL
LEIVNRRFPTAKITLDDIEASWAGLRPLIAANGSSDYNGGNSGKISDKSFKEVIKVVDQFESQEASREDVESVLNDLETS
LAEDKLSPSAVSRGSSLTSSPDGLLTLAGGKITDYRKMAAGAMALIAKILADKYDAHFNEINSKNLPVSGGDIDPHNVDA
TIAFYAKQGTDNGLTNDEALRIANMYGSNAARVFSLIGKVEPTHGLSLAETISLRYALDEEMTLTPVDYLLRRTNHLLFM
RDTLDGLKDGVIATMADYLGWDAATVKAQTELLNQTIAESDLTALKQG

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=609, Percent_Identity=30.3776683087028, Blast_Score=241, Evalue=2e-63,
Organism=Homo sapiens, GI285002231, Length=609, Percent_Identity=30.3776683087028, Blast_Score=241, Evalue=2e-63,
Organism=Escherichia coli, GI2367226, Length=558, Percent_Identity=27.4193548387097, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1788574, Length=416, Percent_Identity=24.7596153846154, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17509253, Length=594, Percent_Identity=29.1245791245791, Blast_Score=209, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI115534726, Length=608, Percent_Identity=29.7697368421053, Blast_Score=205, Evalue=5e-53,
Organism=Saccharomyces cerevisiae, GI6322036, Length=648, Percent_Identity=26.3888888888889, Blast_Score=164, Evalue=3e-41,
Organism=Drosophila melanogaster, GI161077125, Length=612, Percent_Identity=29.7385620915033, Blast_Score=215, Evalue=9e-56,
Organism=Drosophila melanogaster, GI24653942, Length=612, Percent_Identity=29.7385620915033, Blast_Score=215, Evalue=9e-56,
Organism=Drosophila melanogaster, GI24653944, Length=612, Percent_Identity=29.7385620915033, Blast_Score=215, Evalue=9e-56,
Organism=Drosophila melanogaster, GI20130025, Length=612, Percent_Identity=29.7385620915033, Blast_Score=215, Evalue=9e-56,
Organism=Drosophila melanogaster, GI24586295, Length=354, Percent_Identity=30.7909604519774, Blast_Score=158, Evalue=1e-38,
Organism=Drosophila melanogaster, GI19921278, Length=612, Percent_Identity=26.6339869281046, Blast_Score=153, Evalue=3e-37,
Organism=Drosophila melanogaster, GI45550977, Length=459, Percent_Identity=25.4901960784314, Blast_Score=99, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.3.21 [H]

Molecular weight: Translated: 66614; Mature: 66483

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFSATTRQQNIERLQNETLDLLVIGGGITGAGVAIQSTAMNMKTGLIDMQDFAEGTSSR
CCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEHHHHHHHHCCEEHHHHHCCCCCC
STKLVHGGIRYLKTFDVGVVADTVKERAVVQGIAPHIPKPDPMLLPIYDETGATFDLFSV
CCEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEHHHH
KVAMDLYDKLAEVKDPKFTNYTLSREEVLQREPQLNPKHLVGGGVYLDFRNNDARLVIEN
HHHHHHHHHHHHHCCCCCCCEECCHHHHHHCCCCCCCCEEECCEEEEEEECCCCEEHHHH
IKKAHENGGIMASHVKATGLLHDDDGRINGITAEDLLTGASFEIHARIVINTTGPWSDTI
HHHHHHCCCEEEEEEEEEEEEECCCCCCCCEEHHHHHCCCCEEEEEEEEEECCCCHHHHH
RKMDHTEKYQSQMRPTKGVHLVVDAEKLPVPQPTYFDSGDQDGRMIFVVPRENKTYFGTT
HHHHHHHHHHHHCCCCCCEEEEEEHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEECCC
DTDYHGDLKHPTVTQEDVDYLLEIVNRRFPTAKITLDDIEASWAGLRPLIAANGSSDYNG
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCC
GNSGKISDKSFKEVIKVVDQFESQEASREDVESVLNDLETSLAEDKLSPSAVSRGSSLTS
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCC
SPDGLLTLAGGKITDYRKMAAGAMALIAKILADKYDAHFNEINSKNLPVSGGDIDPHNVD
CCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
ATIAFYAKQGTDNGLTNDEALRIANMYGSNAARVFSLIGKVEPTHGLSLAETISLRYALD
EEEEEEEECCCCCCCCCHHHEEEEHHCCCCHHHHHHHHHCCCCCCCCCHHHHHEEEEEEC
EEMTLTPVDYLLRRTNHLLFMRDTLDGLKDGVIATMADYLGWDAATVKAQTELLNQTIAE
CCCEECHHHHHHHHCCCEEEEHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
SDLTALKQG
HHHHHHCCC
>Mature Secondary Structure 
AFSATTRQQNIERLQNETLDLLVIGGGITGAGVAIQSTAMNMKTGLIDMQDFAEGTSSR
CCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEHHHHHHHHCCEEHHHHHCCCCCC
STKLVHGGIRYLKTFDVGVVADTVKERAVVQGIAPHIPKPDPMLLPIYDETGATFDLFSV
CCEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEHHHH
KVAMDLYDKLAEVKDPKFTNYTLSREEVLQREPQLNPKHLVGGGVYLDFRNNDARLVIEN
HHHHHHHHHHHHHCCCCCCCEECCHHHHHHCCCCCCCCEEECCEEEEEEECCCCEEHHHH
IKKAHENGGIMASHVKATGLLHDDDGRINGITAEDLLTGASFEIHARIVINTTGPWSDTI
HHHHHHCCCEEEEEEEEEEEEECCCCCCCCEEHHHHHCCCCEEEEEEEEEECCCCHHHHH
RKMDHTEKYQSQMRPTKGVHLVVDAEKLPVPQPTYFDSGDQDGRMIFVVPRENKTYFGTT
HHHHHHHHHHHHCCCCCCEEEEEEHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEECCC
DTDYHGDLKHPTVTQEDVDYLLEIVNRRFPTAKITLDDIEASWAGLRPLIAANGSSDYNG
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCC
GNSGKISDKSFKEVIKVVDQFESQEASREDVESVLNDLETSLAEDKLSPSAVSRGSSLTS
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCC
SPDGLLTLAGGKITDYRKMAAGAMALIAKILADKYDAHFNEINSKNLPVSGGDIDPHNVD
CCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
ATIAFYAKQGTDNGLTNDEALRIANMYGSNAARVFSLIGKVEPTHGLSLAETISLRYALD
EEEEEEEECCCCCCCCCHHHEEEEHHCCCCHHHHHHHHHCCCCCCCCCHHHHHEEEEEEC
EEMTLTPVDYLLRRTNHLLFMRDTLDGLKDGVIATMADYLGWDAATVKAQTELLNQTIAE
CCCEECHHHHHHHHCCCEEEEHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
SDLTALKQG
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9726992 [H]