Click here to switch to the map view.

The map label for this gene is rpiA2 [H]

Identifier: 28377270

GI number: 28377270

Start: 322679

End: 323347

Strand: Direct

Name: rpiA2 [H]

Synonym: lp_0354

Alternate gene names: 28377270

Gene position: 322679-323347 (Clockwise)

Preceding gene: 28377268

Following gene: 28377271

Centisome position: 9.75

GC content: 46.64

Gene sequence:

>669_bases
ATGACGATTAAACAGGCAATTGTTCAACAAGCCTTGACGTTAATAAAACCGCAAATGGTTGTTGGTTTTGGGGGTGGCTC
GACGGTTGGTGAACTGGTCAAGGAGGCAGCCAATCATGTGAATGATATTACGGTCGTCACCCCATCACCGACGACCCGCC
AACTTGCGACCGTTCTCGGGTATACCGTTGTAGATACTGCATATTGTGACCGCGTCGATATTGCTTTTGACGGCTGCGAT
CAGTTAGATCATCACGGTAACGCGCTCAAAAGTGGCGGTGGAATCCATGCTAATGAGAAGATTATTGCCAGCTTGGCGGA
TGAATATTGGCTGTTAACGATGCAGGACCGGTTAGTCGATCAATTTGATATCAAGACGCCACTAGTCTTAGAAGTACTGC
CAGCGGCCTTATCGTTAGTCATGCGGACGGTGAGTGATCTTGGTGGTCAGGCAACCATTCGAACTGCTAATAATCGGGAT
GGCTTCACGTTAACCGATAGCGGCAATTTATTGATCGATTGTCATTTTCCAACGTATGCCAAACTTACGGACCTGAATGT
TGAATTAGCAACTTTGGCTGGCGTTGTTGAAACGAGCTATTTTGATCATTTGGTGACGAATGCTTGGTTGGGTGATGCGA
CCACGAATACAGTCAAAGCGCTATTTTAA

Upstream 100 bases:

>100_bases
TTTGACCTAGAATCGCATGGTTTGATCGCGATTAAAGTTAGTTAAATAGGTTATCGCGTGCTATGATGAGAATATCTTAT
GATGATGGAAGGAAATTGAT

Downstream 100 bases:

>100_bases
GTGTCATCAGGGACGACCTTAGTAACCAGTAAACGAATGCTGAAATTCGTTTGACACTTTTTTAAAATAATTCTAAACTG
AAGGTGACGTATAAAAGCGC

Product: ribose 5-phosphate epimerase

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MTIKQAIVQQALTLIKPQMVVGFGGGSTVGELVKEAANHVNDITVVTPSPTTRQLATVLGYTVVDTAYCDRVDIAFDGCD
QLDHHGNALKSGGGIHANEKIIASLADEYWLLTMQDRLVDQFDIKTPLVLEVLPAALSLVMRTVSDLGGQATIRTANNRD
GFTLTDSGNLLIDCHFPTYAKLTDLNVELATLAGVVETSYFDHLVTNAWLGDATTNTVKALF

Sequences:

>Translated_222_residues
MTIKQAIVQQALTLIKPQMVVGFGGGSTVGELVKEAANHVNDITVVTPSPTTRQLATVLGYTVVDTAYCDRVDIAFDGCD
QLDHHGNALKSGGGIHANEKIIASLADEYWLLTMQDRLVDQFDIKTPLVLEVLPAALSLVMRTVSDLGGQATIRTANNRD
GFTLTDSGNLLIDCHFPTYAKLTDLNVELATLAGVVETSYFDHLVTNAWLGDATTNTVKALF
>Mature_221_residues
TIKQAIVQQALTLIKPQMVVGFGGGSTVGELVKEAANHVNDITVVTPSPTTRQLATVLGYTVVDTAYCDRVDIAFDGCDQ
LDHHGNALKSGGGIHANEKIIASLADEYWLLTMQDRLVDQFDIKTPLVLEVLPAALSLVMRTVSDLGGQATIRTANNRDG
FTLTDSGNLLIDCHFPTYAKLTDLNVELATLAGVVETSYFDHLVTNAWLGDATTNTVKALF

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=219, Percent_Identity=31.0502283105023, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI1789280, Length=200, Percent_Identity=30, Blast_Score=85, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17551758, Length=193, Percent_Identity=32.1243523316062, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281364072, Length=210, Percent_Identity=29.5238095238095, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 23876; Mature: 23745

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKQAIVQQALTLIKPQMVVGFGGGSTVGELVKEAANHVNDITVVTPSPTTRQLATVLG
CCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHH
YTVVDTAYCDRVDIAFDGCDQLDHHGNALKSGGGIHANEKIIASLADEYWLLTMQDRLVD
HHHHHHHHHCCEEEEECCCHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHEEEEHHHHHHH
QFDIKTPLVLEVLPAALSLVMRTVSDLGGQATIRTANNRDGFTLTDSGNLLIDCHFPTYA
HHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCEEEEECCCCCC
KLTDLNVELATLAGVVETSYFDHLVTNAWLGDATTNTVKALF
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCC
>Mature Secondary Structure 
TIKQAIVQQALTLIKPQMVVGFGGGSTVGELVKEAANHVNDITVVTPSPTTRQLATVLG
CHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHH
YTVVDTAYCDRVDIAFDGCDQLDHHGNALKSGGGIHANEKIIASLADEYWLLTMQDRLVD
HHHHHHHHHCCEEEEECCCHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHEEEEHHHHHHH
QFDIKTPLVLEVLPAALSLVMRTVSDLGGQATIRTANNRDGFTLTDSGNLLIDCHFPTYA
HHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCEEEEECCCCCC
KLTDLNVELATLAGVVETSYFDHLVTNAWLGDATTNTVKALF
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA