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The map label for this gene is dak1B [H]

Identifier: 28377108

GI number: 28377108

Start: 144440

End: 145438

Strand: Direct

Name: dak1B [H]

Synonym: lp_0168

Alternate gene names: 28377108

Gene position: 144440-145438 (Clockwise)

Preceding gene: 28377106

Following gene: 28377109

Centisome position: 4.37

GC content: 44.84

Gene sequence:

>999_bases
ATGAAAAAAATAATTAATGATCCCAAGAATGTCGTCGACGAAATGGTTGATGGGTTAGTACGTGCCTATCCTCAGTATTT
AACTAAATTACCGGATACCGAAGCAATGGTTCGTAGTGATCAAGATTCAATGCAGGGAAAAGTTGGAATTGTTAGTGGTG
GCGGGAGTGGTCATGAGCCCGCCCACGCCGGCTTTGTTGGCCCTGGCATGCTCAGCGCTGCCGTGGCAGGACAGGTTTTC
ACCTCACCGACGCCAGACCAAATTTATGCGGCAATTAAGGCTGTCGATCAAGGTAAGGGCGTTTTCTTAGTCGTGAAGAA
TTATTCTGGTGATGTCATGAATTTCGATATGGCGAAAGATATGGCTGAATTAGATGATATTCAAGTTAAATCGATTGTCG
TTGATGATGACATTGCTGTTAAGGATAGTTTATATACTCAGGGTCGTCGCGGGGTTGCCGGCACTATCTTTATGCATAAG
ATACTTGGGGCGGCCGCGGATCAAGGCGTTGATTTGGATGATTTAGAAAGTTTAGCAACGCATGTTTTACCACGGATTAA
AACGATTGCGGTCGCATTATCCGCAGCGACGGTTCCGGAAGTCGGCAAACCTGGCTTTGAATTGGCAGATGATGAAATCG
AGTTTGGCGTCGGAATCCATAGCGAACCAGGTTATCGGCGCGAAAAAATCAAGCCATCCAAACAACTTGTTCAGGAATTG
CTAGGTAAATTAGATGATGAATTACACCTACAGTCAGATCATCAGTATGCGTTCTTGGTTAATGGTATGGGAGCGACGCC
ATTGATGGATCAGTATGTCTTTTGCCATGACTTGTTGGATGAACTGGCAACACGGCACATTCAACCGGCCTTTATGAAGG
TTGGTAATTATATGACTTCGATTGATATGGCCGGTATTTCACTGACGATATTCGATGTTGCTGAATCTCAGTGGCTAGAT
TACTTACAGTACCCGGTCAAAACAATCGCGTGGTCATAA

Upstream 100 bases:

>100_bases
GTCAGAAGCTGGCGGACAAAATAACGAAACTGTCCATTATTTTTGAAATCGGATTCATTTACAATTAACGTGTTAATTCG
AGAAAGGAAGGACAACAAAA

Downstream 100 bases:

>100_bases
GGAGGAATTGAGAATGTTAACAGTTGAGAACACAACAGTATGGCTGAATAAGTTTGCTGATCAGATTGAACAACACCAAA
GTTACCTAAGTGAATTAGAT

Product: dihydroxyacetone kinase subunit DhaK

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MKKIINDPKNVVDEMVDGLVRAYPQYLTKLPDTEAMVRSDQDSMQGKVGIVSGGGSGHEPAHAGFVGPGMLSAAVAGQVF
TSPTPDQIYAAIKAVDQGKGVFLVVKNYSGDVMNFDMAKDMAELDDIQVKSIVVDDDIAVKDSLYTQGRRGVAGTIFMHK
ILGAAADQGVDLDDLESLATHVLPRIKTIAVALSAATVPEVGKPGFELADDEIEFGVGIHSEPGYRREKIKPSKQLVQEL
LGKLDDELHLQSDHQYAFLVNGMGATPLMDQYVFCHDLLDELATRHIQPAFMKVGNYMTSIDMAGISLTIFDVAESQWLD
YLQYPVKTIAWS

Sequences:

>Translated_332_residues
MKKIINDPKNVVDEMVDGLVRAYPQYLTKLPDTEAMVRSDQDSMQGKVGIVSGGGSGHEPAHAGFVGPGMLSAAVAGQVF
TSPTPDQIYAAIKAVDQGKGVFLVVKNYSGDVMNFDMAKDMAELDDIQVKSIVVDDDIAVKDSLYTQGRRGVAGTIFMHK
ILGAAADQGVDLDDLESLATHVLPRIKTIAVALSAATVPEVGKPGFELADDEIEFGVGIHSEPGYRREKIKPSKQLVQEL
LGKLDDELHLQSDHQYAFLVNGMGATPLMDQYVFCHDLLDELATRHIQPAFMKVGNYMTSIDMAGISLTIFDVAESQWLD
YLQYPVKTIAWS
>Mature_332_residues
MKKIINDPKNVVDEMVDGLVRAYPQYLTKLPDTEAMVRSDQDSMQGKVGIVSGGGSGHEPAHAGFVGPGMLSAAVAGQVF
TSPTPDQIYAAIKAVDQGKGVFLVVKNYSGDVMNFDMAKDMAELDDIQVKSIVVDDDIAVKDSLYTQGRRGVAGTIFMHK
ILGAAADQGVDLDDLESLATHVLPRIKTIAVALSAATVPEVGKPGFELADDEIEFGVGIHSEPGYRREKIKPSKQLVQEL
LGKLDDELHLQSDHQYAFLVNGMGATPLMDQYVFCHDLLDELATRHIQPAFMKVGNYMTSIDMAGISLTIFDVAESQWLD
YLQYPVKTIAWS

Specific function: Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaK domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=337, Percent_Identity=38.2789317507418, Blast_Score=231, Evalue=8e-61,
Organism=Escherichia coli, GI87081857, Length=358, Percent_Identity=42.4581005586592, Blast_Score=268, Evalue=4e-73,
Organism=Caenorhabditis elegans, GI17565018, Length=330, Percent_Identity=32.4242424242424, Blast_Score=181, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6321055, Length=339, Percent_Identity=35.693215339233, Blast_Score=190, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6323570, Length=333, Percent_Identity=34.2342342342342, Blast_Score=162, Evalue=7e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR012736 [H]

Pfam domain/function: PF02733 Dak1 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 36105; Mature: 36105

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIINDPKNVVDEMVDGLVRAYPQYLTKLPDTEAMVRSDQDSMQGKVGIVSGGGSGHEP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHCCCEEEEECCCCCCCC
AHAGFVGPGMLSAAVAGQVFTSPTPDQIYAAIKAVDQGKGVFLVVKNYSGDVMNFDMAKD
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEHHHHHH
MAELDDIQVKSIVVDDDIAVKDSLYTQGRRGVAGTIFMHKILGAAADQGVDLDDLESLAT
HHHHCCCEEEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
HVLPRIKTIAVALSAATVPEVGKPGFELADDEIEFGVGIHSEPGYRREKIKPSKQLVQEL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHH
LGKLDDELHLQSDHQYAFLVNGMGATPLMDQYVFCHDLLDELATRHIQPAFMKVGNYMTS
HHHCCCCEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IDMAGISLTIFDVAESQWLDYLQYPVKTIAWS
HHHCCCEEEEEECHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKIINDPKNVVDEMVDGLVRAYPQYLTKLPDTEAMVRSDQDSMQGKVGIVSGGGSGHEP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHCCCEEEEECCCCCCCC
AHAGFVGPGMLSAAVAGQVFTSPTPDQIYAAIKAVDQGKGVFLVVKNYSGDVMNFDMAKD
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEHHHHHH
MAELDDIQVKSIVVDDDIAVKDSLYTQGRRGVAGTIFMHKILGAAADQGVDLDDLESLAT
HHHHCCCEEEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
HVLPRIKTIAVALSAATVPEVGKPGFELADDEIEFGVGIHSEPGYRREKIKPSKQLVQEL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHH
LGKLDDELHLQSDHQYAFLVNGMGATPLMDQYVFCHDLLDELATRHIQPAFMKVGNYMTS
HHHCCCCEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IDMAGISLTIFDVAESQWLDYLQYPVKTIAWS
HHHCCCEEEEEECHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]