Click here to switch to the map view.

The map label for this gene is fusA1 [H]

Identifier: 28377038

GI number: 28377038

Start: 73239

End: 75257

Strand: Direct

Name: fusA1 [H]

Synonym: lp_0076

Alternate gene names: 28377038

Gene position: 73239-75257 (Clockwise)

Preceding gene: 28377037

Following gene: 28377039

Centisome position: 2.21

GC content: 49.58

Gene sequence:

>2019_bases
ATGAAACGGATTGTAGCGGGAATTATTGCCCACGTCGATGCCGGTAAAACGACGCTGTCAGAAGCATTACTATACCGGTC
TGGCGCGCTACGGCAATTAGGGCGTGTCGATAATGGCGATGCTTTTTTAGATACGGATGTGCTTGAAAAACAGCGTGGTA
TTACGATTTTTTCACACCAAGCTAATTTACAATATAAAGACATTAATTTAACACTCTTGGATACCCCGGGCCACGTCGAT
TTTGCGACCCAGACTGAACAAGTACTGTCGGTTTTGGACGTCGCAATTTTAGTCGTTTCAGCGACTGATGGTGTGCAGGG
GTACACGCGGACGTTATGGCGATTATTAGCCCGTTATGACGTTCCTACCATTCTGTTTGTAAATAAGATGGATGCGCCGG
GGACGGATAGCGACCAATTGATACAACAAATTCAACAGACATTATCGCCTGGTTGTGTGGCGTTTAACACGCCGGGAGCC
GGGGACACGTTGGAAGATCGGCCAGTCATACCGACTGCGGCAGTTGAAGATATTGCGATGCAAAATGACGAAGTGTTAAC
GGATTACTTAGAAACAGGGACGTTAAGTGATGCCACGATTCGGCAGATGATTCAACGGCGGGAAGTTTTTCCGTGTTATT
TTGGCGCGGCACTTAAGCTGGACGGGGTTGATGCGCTAATGACTGGTCTTGATTATTGGACGACGCCACAATTAACGCGT
CCTGAATTTGGCGCGCGGGTGTTCAAGATTACGCACGATGATCAAGGTGAACGGCTTACTTGGATTCGGATGACCGGTGG
CACCTTACGACCTAAAGATATCGTGTATGATGACCAAAAAGTCAATCAGTTACGGGTTTACAACGGGACTAAGTATGCGA
CCACGTCCGCGCTGACGGCAGGATCCGTTGGTGCCATTACCGGTCTAACGGGAACGCGGCCGGGGCAAGGATTGGGACAG
GCAGCAACTAGTCTACAACCCGTCATGCAGCCCGTACTGACTTACGCACTTGATCCTCAGCGTGAGGAGTTACACACCTG
CTTAGCAGCCTTGCGTCAACTTGAAGATGAGGATCCACAATTACACGTGACTTGGTCAGAACCACTTCAGGAATTGCGAG
TACAGGTCATGGGAACGATTCAACTGGAAGTTTTGCAACAAATCTTGCAGGATCGTTTTCAACTGACTGTAAAGTTTGGA
ACGGGGAGTATCTTGTATCAAGAGACGATTACCCAAGCTGTTGAAGGTGTTGGGCATTTTGAACCGTTACGACACTACGC
GGAAGTACATTTGTTGCTGACGCCCGCACCGCGGGGAAGTGGGCTTCAATTTACGACCGATTGTTCATTGGAAGTGCTTG
GCCGAAATTGGCAACACCAAGTCGTGTCAAACCTACAAGCCAAAACACAAGTGGGTGTCCTGATTGGCGCACCACTAACG
GATGTTAAGGTAACACTGGTTAGTGGTCGGGCTAGCAATGTTCATTCGGTTGGTGGTGACTTTCGTGAAGCGACGTGGCG
CGCGTTGCGTCAAGGTTTGATGATGTTAAACCAACGTGGTGATTGTCAGTTATTGGAGCCGTGGTATCGGTTCCGTCTAG
AAATTGGTCAGGAACAAGTTGGCCGGGCGATGACTGATATTCAGCGGATGAATGGTCAGTTTGACGCACCGGTCGCTAAT
ACAAGCGTAGCCACGGACGGGACTGGCCTGACGACAATTACGGGAACGGCGCCAGTAGCAGCGATGCAGGACTATTCACA
GACGGTTCGAGCTTACACGCATGGGCAGGGGCAATTGGAATGTATCGTGGATGGCTATCGGCCGTGTCATAACGAGATGG
CTGTTGTCGATAAGGCCGAATATGTTCCCACAGCAGATTTAGAAAATACACCGGACTCGGTCTTTTGCGCACATGGTGCG
GGTTATCCGGTAGCTTGGAATCAAGTGCCAGAGATGGCGCATGTCCCGTACGTTTATTCGAATACGGAATTGGCACATTT
TAAGGCGTCATCAAAATAG

Upstream 100 bases:

>100_bases
CATGCATATTTAACGTTAGTGGCAGACCTTTACTAGCCGTTCAGTGCTGAGAACCGGTATACTGGAAGCAGTGATTCACT
AATCGTGAAGGGAGCCCAAT

Downstream 100 bases:

>100_bases
AAATTGAGGAAATTCAGATGATGGATGTGACGTTTAATTCGACGTTTGCGGTAACCTTGCAACATGAGTTGCACCAGCCA
GTATTGAGTTTGCCATTGTC

Product: elongation factor G

Products: NA

Alternate protein names: Tet(Q) [H]

Number of amino acids: Translated: 672; Mature: 672

Protein sequence:

>672_residues
MKRIVAGIIAHVDAGKTTLSEALLYRSGALRQLGRVDNGDAFLDTDVLEKQRGITIFSHQANLQYKDINLTLLDTPGHVD
FATQTEQVLSVLDVAILVVSATDGVQGYTRTLWRLLARYDVPTILFVNKMDAPGTDSDQLIQQIQQTLSPGCVAFNTPGA
GDTLEDRPVIPTAAVEDIAMQNDEVLTDYLETGTLSDATIRQMIQRREVFPCYFGAALKLDGVDALMTGLDYWTTPQLTR
PEFGARVFKITHDDQGERLTWIRMTGGTLRPKDIVYDDQKVNQLRVYNGTKYATTSALTAGSVGAITGLTGTRPGQGLGQ
AATSLQPVMQPVLTYALDPQREELHTCLAALRQLEDEDPQLHVTWSEPLQELRVQVMGTIQLEVLQQILQDRFQLTVKFG
TGSILYQETITQAVEGVGHFEPLRHYAEVHLLLTPAPRGSGLQFTTDCSLEVLGRNWQHQVVSNLQAKTQVGVLIGAPLT
DVKVTLVSGRASNVHSVGGDFREATWRALRQGLMMLNQRGDCQLLEPWYRFRLEIGQEQVGRAMTDIQRMNGQFDAPVAN
TSVATDGTGLTTITGTAPVAAMQDYSQTVRAYTHGQGQLECIVDGYRPCHNEMAVVDKAEYVPTADLENTPDSVFCAHGA
GYPVAWNQVPEMAHVPYVYSNTELAHFKASSK

Sequences:

>Translated_672_residues
MKRIVAGIIAHVDAGKTTLSEALLYRSGALRQLGRVDNGDAFLDTDVLEKQRGITIFSHQANLQYKDINLTLLDTPGHVD
FATQTEQVLSVLDVAILVVSATDGVQGYTRTLWRLLARYDVPTILFVNKMDAPGTDSDQLIQQIQQTLSPGCVAFNTPGA
GDTLEDRPVIPTAAVEDIAMQNDEVLTDYLETGTLSDATIRQMIQRREVFPCYFGAALKLDGVDALMTGLDYWTTPQLTR
PEFGARVFKITHDDQGERLTWIRMTGGTLRPKDIVYDDQKVNQLRVYNGTKYATTSALTAGSVGAITGLTGTRPGQGLGQ
AATSLQPVMQPVLTYALDPQREELHTCLAALRQLEDEDPQLHVTWSEPLQELRVQVMGTIQLEVLQQILQDRFQLTVKFG
TGSILYQETITQAVEGVGHFEPLRHYAEVHLLLTPAPRGSGLQFTTDCSLEVLGRNWQHQVVSNLQAKTQVGVLIGAPLT
DVKVTLVSGRASNVHSVGGDFREATWRALRQGLMMLNQRGDCQLLEPWYRFRLEIGQEQVGRAMTDIQRMNGQFDAPVAN
TSVATDGTGLTTITGTAPVAAMQDYSQTVRAYTHGQGQLECIVDGYRPCHNEMAVVDKAEYVPTADLENTPDSVFCAHGA
GYPVAWNQVPEMAHVPYVYSNTELAHFKASSK
>Mature_672_residues
MKRIVAGIIAHVDAGKTTLSEALLYRSGALRQLGRVDNGDAFLDTDVLEKQRGITIFSHQANLQYKDINLTLLDTPGHVD
FATQTEQVLSVLDVAILVVSATDGVQGYTRTLWRLLARYDVPTILFVNKMDAPGTDSDQLIQQIQQTLSPGCVAFNTPGA
GDTLEDRPVIPTAAVEDIAMQNDEVLTDYLETGTLSDATIRQMIQRREVFPCYFGAALKLDGVDALMTGLDYWTTPQLTR
PEFGARVFKITHDDQGERLTWIRMTGGTLRPKDIVYDDQKVNQLRVYNGTKYATTSALTAGSVGAITGLTGTRPGQGLGQ
AATSLQPVMQPVLTYALDPQREELHTCLAALRQLEDEDPQLHVTWSEPLQELRVQVMGTIQLEVLQQILQDRFQLTVKFG
TGSILYQETITQAVEGVGHFEPLRHYAEVHLLLTPAPRGSGLQFTTDCSLEVLGRNWQHQVVSNLQAKTQVGVLIGAPLT
DVKVTLVSGRASNVHSVGGDFREATWRALRQGLMMLNQRGDCQLLEPWYRFRLEIGQEQVGRAMTDIQRMNGQFDAPVAN
TSVATDGTGLTTITGTAPVAAMQDYSQTVRAYTHGQGQLECIVDGYRPCHNEMAVVDKAEYVPTADLENTPDSVFCAHGA
GYPVAWNQVPEMAHVPYVYSNTELAHFKASSK

Specific function: Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes [H]

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TetM/tetO subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=699, Percent_Identity=26.7525035765379, Blast_Score=186, Evalue=5e-47,
Organism=Homo sapiens, GI19923640, Length=705, Percent_Identity=24.6808510638298, Blast_Score=172, Evalue=1e-42,
Organism=Homo sapiens, GI25306287, Length=692, Percent_Identity=24.2774566473988, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI25306283, Length=371, Percent_Identity=29.6495956873315, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI157426893, Length=430, Percent_Identity=23.4883720930233, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI94966754, Length=128, Percent_Identity=33.59375, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI4503483, Length=141, Percent_Identity=34.7517730496454, Blast_Score=73, Evalue=1e-12,
Organism=Escherichia coli, GI1789738, Length=698, Percent_Identity=26.3610315186246, Blast_Score=196, Evalue=4e-51,
Organism=Escherichia coli, GI1790835, Length=316, Percent_Identity=29.746835443038, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI48994988, Length=172, Percent_Identity=36.046511627907, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1788922, Length=171, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1790412, Length=131, Percent_Identity=37.4045801526718, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1789737, Length=131, Percent_Identity=37.4045801526718, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17533571, Length=688, Percent_Identity=25.4360465116279, Blast_Score=179, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17556745, Length=675, Percent_Identity=24.2962962962963, Blast_Score=175, Evalue=8e-44,
Organism=Caenorhabditis elegans, GI17557151, Length=180, Percent_Identity=33.8888888888889, Blast_Score=92, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI71988819, Length=126, Percent_Identity=31.7460317460317, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71988811, Length=126, Percent_Identity=31.7460317460317, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17506493, Length=187, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323098, Length=693, Percent_Identity=24.3867243867244, Blast_Score=169, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6322359, Length=692, Percent_Identity=22.8323699421965, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6323320, Length=144, Percent_Identity=36.1111111111111, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324707, Length=141, Percent_Identity=34.0425531914894, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320593, Length=141, Percent_Identity=34.0425531914894, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24582462, Length=696, Percent_Identity=26.4367816091954, Blast_Score=193, Evalue=3e-49,
Organism=Drosophila melanogaster, GI221458488, Length=710, Percent_Identity=24.5070422535211, Blast_Score=153, Evalue=4e-37,
Organism=Drosophila melanogaster, GI78706572, Length=143, Percent_Identity=34.2657342657343, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24585711, Length=165, Percent_Identity=31.5151515151515, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24585713, Length=165, Percent_Identity=31.5151515151515, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24585709, Length=165, Percent_Identity=31.5151515151515, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28574573, Length=133, Percent_Identity=35.3383458646617, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR002127
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 73934; Mature: 73934

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIVAGIIAHVDAGKTTLSEALLYRSGALRQLGRVDNGDAFLDTDVLEKQRGITIFSHQ
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEECHHHHHHHCCCEEEEEC
ANLQYKDINLTLLDTPGHVDFATQTEQVLSVLDVAILVVSATDGVQGYTRTLWRLLARYD
CCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHCC
VPTILFVNKMDAPGTDSDQLIQQIQQTLSPGCVAFNTPGAGDTLEDRPVIPTAAVEDIAM
CCEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHH
QNDEVLTDYLETGTLSDATIRQMIQRREVFPCYFGAALKLDGVDALMTGLDYWTTPQLTR
CCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCEECCCEEEECCHHHHHHCCCCCCCCCCCC
PEFGARVFKITHDDQGERLTWIRMTGGTLRPKDIVYDDQKVNQLRVYNGTKYATTSALTA
CCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCEECCCCCCEEEEECCCCEEEHHHHCC
GSVGAITGLTGTRPGQGLGQAATSLQPVMQPVLTYALDPQREELHTCLAALRQLEDEDPQ
CCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCE
LHVTWSEPLQELRVQVMGTIQLEVLQQILQDRFQLTVKFGTGSILYQETITQAVEGVGHF
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHCCCH
EPLRHYAEVHLLLTPAPRGSGLQFTTDCSLEVLGRNWQHQVVSNLQAKTQVGVLIGAPLT
HHHHHHEEEEEEEECCCCCCCCEEECCCCCEECCCCHHHHHHHHHHHHHEEEEEEECCCC
DVKVTLVSGRASNVHSVGGDFREATWRALRQGLMMLNQRGDCQLLEPWYRFRLEIGQEQV
CEEEEEEECCCCCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHCCHHHH
GRAMTDIQRMNGQFDAPVANTSVATDGTGLTTITGTAPVAAMQDYSQTVRAYTHGQGQLE
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCEEE
CIVDGYRPCHNEMAVVDKAEYVPTADLENTPDSVFCAHGAGYPVAWNQVPEMAHVPYVYS
EEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHCCCEEEC
NTELAHFKASSK
CCEEEEEECCCC
>Mature Secondary Structure
MKRIVAGIIAHVDAGKTTLSEALLYRSGALRQLGRVDNGDAFLDTDVLEKQRGITIFSHQ
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEECHHHHHHHCCCEEEEEC
ANLQYKDINLTLLDTPGHVDFATQTEQVLSVLDVAILVVSATDGVQGYTRTLWRLLARYD
CCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHCC
VPTILFVNKMDAPGTDSDQLIQQIQQTLSPGCVAFNTPGAGDTLEDRPVIPTAAVEDIAM
CCEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHH
QNDEVLTDYLETGTLSDATIRQMIQRREVFPCYFGAALKLDGVDALMTGLDYWTTPQLTR
CCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCEECCCEEEECCHHHHHHCCCCCCCCCCCC
PEFGARVFKITHDDQGERLTWIRMTGGTLRPKDIVYDDQKVNQLRVYNGTKYATTSALTA
CCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCEECCCCCCEEEEECCCCEEEHHHHCC
GSVGAITGLTGTRPGQGLGQAATSLQPVMQPVLTYALDPQREELHTCLAALRQLEDEDPQ
CCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCE
LHVTWSEPLQELRVQVMGTIQLEVLQQILQDRFQLTVKFGTGSILYQETITQAVEGVGHF
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHCCCH
EPLRHYAEVHLLLTPAPRGSGLQFTTDCSLEVLGRNWQHQVVSNLQAKTQVGVLIGAPLT
HHHHHHEEEEEEEECCCCCCCCEEECCCCCEECCCCHHHHHHHHHHHHHEEEEEEECCCC
DVKVTLVSGRASNVHSVGGDFREATWRALRQGLMMLNQRGDCQLLEPWYRFRLEIGQEQV
CEEEEEEECCCCCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHCCHHHH
GRAMTDIQRMNGQFDAPVANTSVATDGTGLTTITGTAPVAAMQDYSQTVRAYTHGQGQLE
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCEEE
CIVDGYRPCHNEMAVVDKAEYVPTADLENTPDSVFCAHGAGYPVAWNQVPEMAHVPYVYS
EEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHCCCEEEC
NTELAHFKASSK
CCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA