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The map label for this gene is cisA [H]

Identifier: 28211764

GI number: 28211764

Start: 2279888

End: 2281387

Strand: Direct

Name: cisA [H]

Synonym: CTC02152

Alternate gene names: 28211764

Gene position: 2279888-2281387 (Clockwise)

Preceding gene: 28211763

Following gene: 28211770

Centisome position: 81.45

GC content: 27.53

Gene sequence:

>1500_bases
ATGGAGGATGATTTTATGAGGGCGGTAGCATATGCTAGATTTAGTTCTGATAATCAAAGAGAAGAATCCATTGAAGCTCA
AATTATGGACATAAAAAAATATGCACTTAAAAACAATATTACAGTGCTTAGAGAATACGTTGATGAAGCTATATCTGGCA
GAACTTTTGAAAGAAAATCTTTTAAAAGAATGATTGAAGATGCTAAAAAAAATATGTTTGATCTGATACTAGTCCATAAA
GTAGATAGATTTGCAAGAAATAGATATGACGCTGCTATCTACAAATCTATACTTAAAAAACATAATATAAAAATAAAATA
TGTCATGCAGCCAATTGATGATTCTCCTGAAGGAAATCTTATGGAGGGTATTCTTGAAAGTTTTGCTGAATATTATTCTG
AAAATCTAGCTAATGAGGTTATGAAAGGATTAAAAATCAATGCAAAAAAAGCTCAATTTAACGGTGGATACCCACCACTA
GGGTATGATATAGCAGAAGACAAGACATATATAATAAATGAAAGGGAAGCTAGAATAGTACGCGAAATATTTGATTTATA
TTTAGATGGTATTGGTTATAAAAAAATTGCTGATATTTTGAATAATAAAGGTTATAAAAATAAAAGAGGAAAACCTTTCG
TTTTTAACTCAATTCCAACTATCCTAAAAAATGATAAATATTGTGGAATATATACATATAATAAAACTAGTAGAAAATAC
AAAAATGGTAGACGAAACCTTAAAAAATATAACAAAGATGAAGATATAATTAGAGTTGAAGATGGTATACCTAAAATAAT
TTCAAAAGAAAAATTTAATACCGCACAACAAGAAATAAAAAAGCGTACAAAGTCTAGAGGTAAAAAAATTGCTGTAAGAG
AATATATTTTATCTGGATTAATAAAATGTGAATGTGAAAGAAAAATGAGTGGGTACGCACAAAAACGTTCCAAAGAAAGT
AATCGATACTTTTATTATAGATGCACTGGATGTAATAACAGTATTAGAGCTGAAAAAATAGAAACTATAGCTACTAATTT
TATAAAAGAACAGGTATTCAGAGATATAGATAATTTAATTATAAAAATACATAAATATATAGCTGATCAAGAAGCAGAAT
CCCCATCTGAACTTAAATATTTAAAAAATGAATTATCTAATTCTAATAACCAAATCAATAACATTGTAAAAATGATTAGT
AACGGAGTAACATCCATGCACTTAGCAAAAAAACTAGAGGAACTTGAAACATATATTGATGGAATACAACAACGAATTGG
TGAAATAAATAGAATGTCTGTTATACCAGAAGATGAAATAAAAAACTGGTTACTAGAACTTAAAAATTCTTTTGATAATG
GTAAAAATATAAAAAAGATAATCTCTGTTTTCATAAAAAACATTGAAATAACGAAAGAAGATATTAATATAGATTTTTTC
GTAAAAGCACCCTATAAGGGTGCGAACAGTCTAAGTGTCGCTCCTTCGGCACCATATTGA

Upstream 100 bases:

>100_bases
GATAAAATGACTAATAGAGATTTAATAGAATTTGCAAATGAACTTTTAAATCAACTAAAATTAATATCTTATAAATATAA
GAATAACATTTAATTTAAAA

Downstream 100 bases:

>100_bases
AAAGCAAAACCCCTAACCTATTGAAAACATTGTGTTTCTAGGTTAGGGGGGTTTTTAGGCTATGTGCAAATATTCATAAT
AATATTAATTTCCTATTCCT

Product: DNA integration/recombination protein

Products: NA

Alternate protein names: Stage IV sporulation protein CA [H]

Number of amino acids: Translated: 499; Mature: 499

Protein sequence:

>499_residues
MEDDFMRAVAYARFSSDNQREESIEAQIMDIKKYALKNNITVLREYVDEAISGRTFERKSFKRMIEDAKKNMFDLILVHK
VDRFARNRYDAAIYKSILKKHNIKIKYVMQPIDDSPEGNLMEGILESFAEYYSENLANEVMKGLKINAKKAQFNGGYPPL
GYDIAEDKTYIINEREARIVREIFDLYLDGIGYKKIADILNNKGYKNKRGKPFVFNSIPTILKNDKYCGIYTYNKTSRKY
KNGRRNLKKYNKDEDIIRVEDGIPKIISKEKFNTAQQEIKKRTKSRGKKIAVREYILSGLIKCECERKMSGYAQKRSKES
NRYFYYRCTGCNNSIRAEKIETIATNFIKEQVFRDIDNLIIKIHKYIADQEAESPSELKYLKNELSNSNNQINNIVKMIS
NGVTSMHLAKKLEELETYIDGIQQRIGEINRMSVIPEDEIKNWLLELKNSFDNGKNIKKIISVFIKNIEITKEDINIDFF
VKAPYKGANSLSVAPSAPY

Sequences:

>Translated_499_residues
MEDDFMRAVAYARFSSDNQREESIEAQIMDIKKYALKNNITVLREYVDEAISGRTFERKSFKRMIEDAKKNMFDLILVHK
VDRFARNRYDAAIYKSILKKHNIKIKYVMQPIDDSPEGNLMEGILESFAEYYSENLANEVMKGLKINAKKAQFNGGYPPL
GYDIAEDKTYIINEREARIVREIFDLYLDGIGYKKIADILNNKGYKNKRGKPFVFNSIPTILKNDKYCGIYTYNKTSRKY
KNGRRNLKKYNKDEDIIRVEDGIPKIISKEKFNTAQQEIKKRTKSRGKKIAVREYILSGLIKCECERKMSGYAQKRSKES
NRYFYYRCTGCNNSIRAEKIETIATNFIKEQVFRDIDNLIIKIHKYIADQEAESPSELKYLKNELSNSNNQINNIVKMIS
NGVTSMHLAKKLEELETYIDGIQQRIGEINRMSVIPEDEIKNWLLELKNSFDNGKNIKKIISVFIKNIEITKEDINIDFF
VKAPYKGANSLSVAPSAPY
>Mature_499_residues
MEDDFMRAVAYARFSSDNQREESIEAQIMDIKKYALKNNITVLREYVDEAISGRTFERKSFKRMIEDAKKNMFDLILVHK
VDRFARNRYDAAIYKSILKKHNIKIKYVMQPIDDSPEGNLMEGILESFAEYYSENLANEVMKGLKINAKKAQFNGGYPPL
GYDIAEDKTYIINEREARIVREIFDLYLDGIGYKKIADILNNKGYKNKRGKPFVFNSIPTILKNDKYCGIYTYNKTSRKY
KNGRRNLKKYNKDEDIIRVEDGIPKIISKEKFNTAQQEIKKRTKSRGKKIAVREYILSGLIKCECERKMSGYAQKRSKES
NRYFYYRCTGCNNSIRAEKIETIATNFIKEQVFRDIDNLIIKIHKYIADQEAESPSELKYLKNELSNSNNQINNIVKMIS
NGVTSMHLAKKLEELETYIDGIQQRIGEINRMSVIPEDEIKNWLLELKNSFDNGKNIKKIISVFIKNIEITKEDINIDFF
VKAPYKGANSLSVAPSAPY

Specific function: Putative site-specific recombinase having a very important role in sporulation. It probably plays a role in the recombination of spoIIIC and spoIVCB to form sigma K factor [H]

COG id: COG1961

COG function: function code L; Site-specific recombinases, DNA invertase Pin homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 recombinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011109
- InterPro:   IPR006118
- InterPro:   IPR006119 [H]

Pfam domain/function: PF07508 Recombinase; PF00239 Resolvase [H]

EC number: NA

Molecular weight: Translated: 58133; Mature: 58133

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDDFMRAVAYARFSSDNQREESIEAQIMDIKKYALKNNITVLREYVDEAISGRTFERKS
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHH
FKRMIEDAKKNMFDLILVHKVDRFARNRYDAAIYKSILKKHNIKIKYVMQPIDDSPEGNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHH
MEGILESFAEYYSENLANEVMKGLKINAKKAQFNGGYPPLGYDIAEDKTYIINEREARIV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHH
REIFDLYLDGIGYKKIADILNNKGYKNKRGKPFVFNSIPTILKNDKYCGIYTYNKTSRKY
HHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCEEECCCHHHHCCCCEEEEEEECCHHHHH
KNGRRNLKKYNKDEDIIRVEDGIPKIISKEKFNTAQQEIKKRTKSRGKKIAVREYILSGL
HHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
IKCECERKMSGYAQKRSKESNRYFYYRCTGCNNSIRAEKIETIATNFIKEQVFRDIDNLI
HHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IKIHKYIADQEAESPSELKYLKNELSNSNNQINNIVKMISNGVTSMHLAKKLEELETYID
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
GIQQRIGEINRMSVIPEDEIKNWLLELKNSFDNGKNIKKIISVFIKNIEITKEDINIDFF
HHHHHHCCHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCEEEHHHCCEEEE
VKAPYKGANSLSVAPSAPY
EECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEDDFMRAVAYARFSSDNQREESIEAQIMDIKKYALKNNITVLREYVDEAISGRTFERKS
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHH
FKRMIEDAKKNMFDLILVHKVDRFARNRYDAAIYKSILKKHNIKIKYVMQPIDDSPEGNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHH
MEGILESFAEYYSENLANEVMKGLKINAKKAQFNGGYPPLGYDIAEDKTYIINEREARIV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHH
REIFDLYLDGIGYKKIADILNNKGYKNKRGKPFVFNSIPTILKNDKYCGIYTYNKTSRKY
HHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCEEECCCHHHHCCCCEEEEEEECCHHHHH
KNGRRNLKKYNKDEDIIRVEDGIPKIISKEKFNTAQQEIKKRTKSRGKKIAVREYILSGL
HHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
IKCECERKMSGYAQKRSKESNRYFYYRCTGCNNSIRAEKIETIATNFIKEQVFRDIDNLI
HHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IKIHKYIADQEAESPSELKYLKNELSNSNNQINNIVKMISNGVTSMHLAKKLEELETYID
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
GIQQRIGEINRMSVIPEDEIKNWLLELKNSFDNGKNIKKIISVFIKNIEITKEDINIDFF
HHHHHHCCHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCEEEHHHCCEEEE
VKAPYKGANSLSVAPSAPY
EECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2105293; 7704261; 8969508; 9384377 [H]