Click here to switch to the map view.

The map label for this gene is cat [H]

Identifier: 28211102

GI number: 28211102

Start: 1538200

End: 1538826

Strand: Direct

Name: cat [H]

Synonym: CTC01425

Alternate gene names: 28211102

Gene position: 1538200-1538826 (Clockwise)

Preceding gene: 28211093

Following gene: 28211107

Centisome position: 54.95

GC content: 24.88

Gene sequence:

>627_bases
ATGGAATATATTGATTTTAATAATTGGGCAAGAAAAGAACACTTCGAATTTTTTAAAGGTGCTAATAATCCTCAATTTAA
TATTTGCATGAATCTAGATATTACACACTTTCTAAAGTTTGTAAAAGACAATGATTTATCCTTTTATTTTAGTATGGTTT
ATGCATCTACATATGTTATGAATGAAATGGAAGATTTTCGATATAAGATTAGAAAAGATGGTATAGTTCTTCATGACTAT
TTAATACCATCCTTTACTGATATGAGTAATAGGGATAATTTATATAAAATTATTACATTACCTTTAAGCGATGATATAAA
AAGCTTTTCAACTATTGCAAAGAAAACTTCTAAATCTCAACAGAAGTTTTTTCCTAAAATAGATTTTGATCAAGACAAAT
TAATTTATTTTTCATGTATACCTTGGATTTCATTTACTAGTGTTTCAAATGAAATGGTTATGGACGAGAATGATTCTATT
CCTAGAATATCCTTTGGAAAATACTTTACTAAAGATAATAAAGTGTTACTACCATATTCTATACAGGTAAATCATAAGCT
TTTAGATGGGTACCATGTTGGATATTTTATAGAAAAATTACAAGAGTATATTAATAAAATAAAATAA

Upstream 100 bases:

>100_bases
ATGCGGATTCATTTTATTATATGGGACATTTGTCAGTTACTTTTTAAAAAACATATGATAGAATAATATCTAAAACTACT
AATTACTAAAGGAGAACGCT

Downstream 100 bases:

>100_bases
AAAGGGTAGATTAAATTTACTCTTGATAAATTTAATCTACCCTTTTTATTTCCTACGCATTACTCTTCTATTTTCCTTTA
TTAAACCTTTTACAAATCTT

Product: chloramphenicol acetyltransferase

Products: NA

Alternate protein names: CAT [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MEYIDFNNWARKEHFEFFKGANNPQFNICMNLDITHFLKFVKDNDLSFYFSMVYASTYVMNEMEDFRYKIRKDGIVLHDY
LIPSFTDMSNRDNLYKIITLPLSDDIKSFSTIAKKTSKSQQKFFPKIDFDQDKLIYFSCIPWISFTSVSNEMVMDENDSI
PRISFGKYFTKDNKVLLPYSIQVNHKLLDGYHVGYFIEKLQEYINKIK

Sequences:

>Translated_208_residues
MEYIDFNNWARKEHFEFFKGANNPQFNICMNLDITHFLKFVKDNDLSFYFSMVYASTYVMNEMEDFRYKIRKDGIVLHDY
LIPSFTDMSNRDNLYKIITLPLSDDIKSFSTIAKKTSKSQQKFFPKIDFDQDKLIYFSCIPWISFTSVSNEMVMDENDSI
PRISFGKYFTKDNKVLLPYSIQVNHKLLDGYHVGYFIEKLQEYINKIK
>Mature_208_residues
MEYIDFNNWARKEHFEFFKGANNPQFNICMNLDITHFLKFVKDNDLSFYFSMVYASTYVMNEMEDFRYKIRKDGIVLHDY
LIPSFTDMSNRDNLYKIITLPLSDDIKSFSTIAKKTSKSQQKFFPKIDFDQDKLIYFSCIPWISFTSVSNEMVMDENDSI
PRISFGKYFTKDNKVLLPYSIQVNHKLLDGYHVGYFIEKLQEYINKIK

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG4845

COG function: function code V; Chloramphenicol O-acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloramphenicol acetyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023213
- InterPro:   IPR018372
- InterPro:   IPR001707
- ProDom:   PD002660 [H]

Pfam domain/function: PF00302 CAT [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 24862; Mature: 24862

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYIDFNNWARKEHFEFFKGANNPQFNICMNLDITHFLKFVKDNDLSFYFSMVYASTYVM
CCEECCCCCHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHH
NEMEDFRYKIRKDGIVLHDYLIPSFTDMSNRDNLYKIITLPLSDDIKSFSTIAKKTSKSQ
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCHHH
QKFFPKIDFDQDKLIYFSCIPWISFTSVSNEMVMDENDSIPRISFGKYFTKDNKVLLPYS
HHCCCCCCCCCCCEEEEEECCCEEEECCCCCEEECCCCCCCEEECCCEEECCCCEEEEEE
IQVNHKLLDGYHVGYFIEKLQEYINKIK
EEECCEEECCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEYIDFNNWARKEHFEFFKGANNPQFNICMNLDITHFLKFVKDNDLSFYFSMVYASTYVM
CCEECCCCCHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHH
NEMEDFRYKIRKDGIVLHDYLIPSFTDMSNRDNLYKIITLPLSDDIKSFSTIAKKTSKSQ
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCHHH
QKFFPKIDFDQDKLIYFSCIPWISFTSVSNEMVMDENDSIPRISFGKYFTKDNKVLLPYS
HHCCCCCCCCCCCEEEEEECCCEEEECCCCCEEECCCCCCCEEECCCEEECCCCEEEEEE
IQVNHKLLDGYHVGYFIEKLQEYINKIK
EEECCEEECCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1650008 [H]