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The map label for this gene is dapG [H]

Identifier: 28210968

GI number: 28210968

Start: 1376844

End: 1378049

Strand: Direct

Name: dapG [H]

Synonym: CTC01282

Alternate gene names: 28210968

Gene position: 1376844-1378049 (Clockwise)

Preceding gene: 28210967

Following gene: 28210969

Centisome position: 49.19

GC content: 28.44

Gene sequence:

>1206_bases
ATGAAAATAATAGTACAAAAATTTGGAGGTACTTCTGTTTCTACTAAAGAGAGAAGACAAAGAGTTGTAGAAAAAATCAT
AAAAGCTAAAAATGCTGGATATAGTCCTGTAGTTGTGGTATCCGCTATGGGAAGAAAGGGAGAACCTTATGCAACGGATA
CATTACTATCTTTAGTTAGTAATGAACTAAAGAAGAATAATTTAGCTATAGATCTTTTAATGAGTTGTGGAGAAATAATA
AGTACTGTTGTTATGGCTGATGAACTTTTATCTAAAAATATAGACGCAGTACCTTTAACAGGAGGACAAGCTGGAATATT
AACAGATGATAATTATAGCAACGCATCCATATTAAAATTAGAATGTGATAAAATATTGGATGTGGTAGAAGAAAATAAAA
TCCCAATAGTAGCTGGTTTTCAAGGAATTAGTGAAAATGGATTTATAACTACTTTAGGTAGAGGAGGAAGTGACGTTACA
GCGGTTCTACTTGGAGGAGCATTAAAGGCAGAAAAAGTAGAAATATATACAGATGTAGATGGAATAATGACCGCAGATCC
AAGGATAGTATCTGATGCTACTTTGATAAAAGAAATAAGTTATAATGAAACTTTCCAATTTTCTCATGAAGGAGCAAAGG
TTATACATCCAAGAGCAGTAGAAATAGCAATGAATGAAAACATCCCTATAGTAATAAAAAATACTTTAACTAATTGTGAT
GGAACTTTAATAAATAATATAAGTGATTTAAATTTAAATAATATAATAACAGGAATTACTCATACCAATGATAGGACTCA
AATAAAAATAGAACTTGAACAAAATAAAGAAAATGAAAGTTATTTTAGAATACTAGATATATTAGCTGAAAATTCCATAA
GTATAGATTTAATTAATGTATTCCCAAGAGAAAGTATATTTACTATTGATGGGAAGGATTTTGAAAAATTTAGTAGCATA
ATGAATAAAATTAATTTAAAATACTCTCACATAGATAGCTGTAGTAAAATTGCTATTATAGGAAATAGAATGAGAGGTAT
TCCTGGAGTAATGGCAAAAATAATTTATGTATTAATGAATGAAAATATAGAAGTATTACAAACAGCCGACTCTCACGCTA
CAATCTGGTGTTTAGTAAAAGATATTCATACAGAAAAAGCTATAAAAGCATTACACAATGCATTTAATTTATCTAATAAT
AAATAA

Upstream 100 bases:

>100_bases
CCCTGGGAATATGTAAAAAAAATAGGAACGAGAACTATAATAATAGATATAGAGGAGTCCACATTAAAAAATAGCCGTAT
ATGAAGCAGGGAGGAACATT

Downstream 100 bases:

>100_bases
AAAGAGTATAATAGCCTTCTCTTATGTACAAAATAAAATTGTGCATAGGGAGGGATTTTTTATGTTAAATGAAGAAAAAA
GAGAAGAAAATAATTTAGAA

Product: aspartate kinase I

Products: NA

Alternate protein names: Aspartate kinase 1; Aspartokinase I [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MKIIVQKFGGTSVSTKERRQRVVEKIIKAKNAGYSPVVVVSAMGRKGEPYATDTLLSLVSNELKKNNLAIDLLMSCGEII
STVVMADELLSKNIDAVPLTGGQAGILTDDNYSNASILKLECDKILDVVEENKIPIVAGFQGISENGFITTLGRGGSDVT
AVLLGGALKAEKVEIYTDVDGIMTADPRIVSDATLIKEISYNETFQFSHEGAKVIHPRAVEIAMNENIPIVIKNTLTNCD
GTLINNISDLNLNNIITGITHTNDRTQIKIELEQNKENESYFRILDILAENSISIDLINVFPRESIFTIDGKDFEKFSSI
MNKINLKYSHIDSCSKIAIIGNRMRGIPGVMAKIIYVLMNENIEVLQTADSHATIWCLVKDIHTEKAIKALHNAFNLSNN
K

Sequences:

>Translated_401_residues
MKIIVQKFGGTSVSTKERRQRVVEKIIKAKNAGYSPVVVVSAMGRKGEPYATDTLLSLVSNELKKNNLAIDLLMSCGEII
STVVMADELLSKNIDAVPLTGGQAGILTDDNYSNASILKLECDKILDVVEENKIPIVAGFQGISENGFITTLGRGGSDVT
AVLLGGALKAEKVEIYTDVDGIMTADPRIVSDATLIKEISYNETFQFSHEGAKVIHPRAVEIAMNENIPIVIKNTLTNCD
GTLINNISDLNLNNIITGITHTNDRTQIKIELEQNKENESYFRILDILAENSISIDLINVFPRESIFTIDGKDFEKFSSI
MNKINLKYSHIDSCSKIAIIGNRMRGIPGVMAKIIYVLMNENIEVLQTADSHATIWCLVKDIHTEKAIKALHNAFNLSNN
K
>Mature_401_residues
MKIIVQKFGGTSVSTKERRQRVVEKIIKAKNAGYSPVVVVSAMGRKGEPYATDTLLSLVSNELKKNNLAIDLLMSCGEII
STVVMADELLSKNIDAVPLTGGQAGILTDDNYSNASILKLECDKILDVVEENKIPIVAGFQGISENGFITTLGRGGSDVT
AVLLGGALKAEKVEIYTDVDGIMTADPRIVSDATLIKEISYNETFQFSHEGAKVIHPRAVEIAMNENIPIVIKNTLTNCD
GTLINNISDLNLNNIITGITHTNDRTQIKIELEQNKENESYFRILDILAENSISIDLINVFPRESIFTIDGKDFEKFSSI
MNKINLKYSHIDSCSKIAIIGNRMRGIPGVMAKIIYVLMNENIEVLQTADSHATIWCLVKDIHTEKAIKALHNAFNLSNN
K

Specific function: Catalyzes 2 nonconsecutive reactions in the common biosynthetic pathway leading from Asp to diaminopimelate and Lys, to Met, and to Thr and Ile. [C]

COG id: COG0527

COG function: function code E; Aspartokinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartokinase family [H]

Homologues:

Organism=Escherichia coli, GI1786183, Length=465, Percent_Identity=26.8817204301075, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1790455, Length=449, Percent_Identity=25.6124721603563, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790376, Length=115, Percent_Identity=30.4347826086957, Blast_Score=63, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320893, Length=360, Percent_Identity=25.8333333333333, Blast_Score=104, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR005260
- InterPro:   IPR001341
- InterPro:   IPR018042 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.4 [H]

Molecular weight: Translated: 44068; Mature: 44068

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS00324 ASPARTOKINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIVQKFGGTSVSTKERRQRVVEKIIKAKNAGYSPVVVVSAMGRKGEPYATDTLLSLVS
CEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHH
NELKKNNLAIDLLMSCGEIISTVVMADELLSKNIDAVPLTGGQAGILTDDNYSNASILKL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCCCCEEEEE
ECDKILDVVEENKIPIVAGFQGISENGFITTLGRGGSDVTAVLLGGALKAEKVEIYTDVD
EHHHHHHHHHCCCCEEEECCCCCCCCCCEEEECCCCCCEEEEEECCCCCCCEEEEEECCC
GIMTADPRIVSDATLIKEISYNETFQFSHEGAKVIHPRAVEIAMNENIPIVIKNTLTNCD
CEEECCCCEECCHHHHHHCCCCCEEEECCCCCEEECCEEEEEEECCCCCEEEEECCCCCC
GTLINNISDLNLNNIITGITHTNDRTQIKIELEQNKENESYFRILDILAENSISIDLINV
CHHHCCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEE
FPRESIFTIDGKDFEKFSSIMNKINLKYSHIDSCSKIAIIGNRMRGIPGVMAKIIYVLMN
CCCCCEEEECCCCHHHHHHHHHHHCCEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHC
ENIEVLQTADSHATIWCLVKDIHTEKAIKALHNAFNLSNNK
CCEEEEEECCCCEEEEEEEEHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKIIVQKFGGTSVSTKERRQRVVEKIIKAKNAGYSPVVVVSAMGRKGEPYATDTLLSLVS
CEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHH
NELKKNNLAIDLLMSCGEIISTVVMADELLSKNIDAVPLTGGQAGILTDDNYSNASILKL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCCCCEEEEE
ECDKILDVVEENKIPIVAGFQGISENGFITTLGRGGSDVTAVLLGGALKAEKVEIYTDVD
EHHHHHHHHHCCCCEEEECCCCCCCCCCEEEECCCCCCEEEEEECCCCCCCEEEEEECCC
GIMTADPRIVSDATLIKEISYNETFQFSHEGAKVIHPRAVEIAMNENIPIVIKNTLTNCD
CEEECCCCEECCHHHHHHCCCCCEEEECCCCCEEECCEEEEEEECCCCCEEEEECCCCCC
GTLINNISDLNLNNIITGITHTNDRTQIKIELEQNKENESYFRILDILAENSISIDLINV
CHHHCCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEE
FPRESIFTIDGKDFEKFSSIMNKINLKYSHIDSCSKIAIIGNRMRGIPGVMAKIIYVLMN
CCCCCEEEECCCCHHHHHHHHHHHCCEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHC
ENIEVLQTADSHATIWCLVKDIHTEKAIKALHNAFNLSNNK
CCEEEEEECCCCEEEEEEEEHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8098035; 9384377 [H]