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The map label for this gene is mgpA [H]

Identifier: 28210963

GI number: 28210963

Start: 1369713

End: 1370687

Strand: Direct

Name: mgpA [H]

Synonym: CTC01277

Alternate gene names: 28210963

Gene position: 1369713-1370687 (Clockwise)

Preceding gene: 28210962

Following gene: 28210964

Centisome position: 48.93

GC content: 29.13

Gene sequence:

>975_bases
ATGAAGACCATGATAACAAATAAAATATTAGATTTAATAATGGAAAGTAACAAAATAGCATTAACTTTCCATGTGTCTCC
AGATGGTGATTCTATAGGAAGTACTTTAGCTTTATATCAAGGTATATCCTCTTTAAAAAAAGATGTATATATTATATCAA
AAGAAGATATACCAGAAGATTTTAAGTTTTTATCCTGTGCTGGTGCAATAACTAAAAGTCATGGAGAGGTTTTAGATGGA
ACGGAGTTAGTTATAGTATTGGATTGTGGAAATTTTGCAAGGGTAAATGCTAATATAGATATTGAAAATAAAAAATATAT
CTTTATTAATATAGATCATCATATATCCAATGAATTATATGGAGATTATAACTTTGTAGATCCTAATGCAGCTTGTATGG
GGGAGATAGTATATCAAATGTTAAAATCTTTAGATGTTAACATAAATAAGGATATAGCAACTTGTTTATACACATCTATA
TTAACGGATACAGGATCTTTTAGACATTCAAATACTACTTCTGTAACCCATTGTGTTGCTGGGGATTTAATAACTACAGG
TATAGATTTTAGTAGCATACACAGAAAAATATTTGATAATAAAAATTTTATTAGATTTAAGCTTTATGGGGAAGTTTTTA
ATGACATGGAGTTAATAGAAGATGAGATTTGTGTTATGAAAGTTACACAGGAAATGTTTAAAAAGTTTAATATAGACTCT
GGAGAAGATACTTCTGATATAGTTTCCTTTGGAGGAACTATGAAAGAAGTGGATGTAACTCTTCTTTTAAAAGAAAAAGA
TGAGGAAATAAAAATAAGTTTAAGATCTAAGTCTAAAGCGGATGTAAGGAATGTAGCAGAGAAGCTTGGTGGAGGCGGAC
ATATAAGGGCTGCTGGAGCTTCTGTTAAGGGAAAAACCTTAGAAGAAGTAAAAAATATAGCAATAGATTTAATAAAAAAA
GAGCTGATGAAATGA

Upstream 100 bases:

>100_bases
AGAATTAAATTAAGATATACACCAGAGATTATTATACAAAATGATGATTCTATAGAGCATGGTATGCACATAGATTCTAT
TTTGGATAAAATCAAGGAGA

Downstream 100 bases:

>100_bases
ATGGTGTAATAAATGTATATAAGCCTCAAAATATTACCTCTTTTGATGTGGTAAGAATTATTAAAAAAATAAGTAGAATA
AAAAAAGTAGGGCATACAGG

Product: mgpA protein

Products: NA

Alternate protein names: 3'(2'),5'-bisphosphate nucleotidase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; nanoRNAse [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MKTMITNKILDLIMESNKIALTFHVSPDGDSIGSTLALYQGISSLKKDVYIISKEDIPEDFKFLSCAGAITKSHGEVLDG
TELVIVLDCGNFARVNANIDIENKKYIFINIDHHISNELYGDYNFVDPNAACMGEIVYQMLKSLDVNINKDIATCLYTSI
LTDTGSFRHSNTTSVTHCVAGDLITTGIDFSSIHRKIFDNKNFIRFKLYGEVFNDMELIEDEICVMKVTQEMFKKFNIDS
GEDTSDIVSFGGTMKEVDVTLLLKEKDEEIKISLRSKSKADVRNVAEKLGGGGHIRAAGASVKGKTLEEVKNIAIDLIKK
ELMK

Sequences:

>Translated_324_residues
MKTMITNKILDLIMESNKIALTFHVSPDGDSIGSTLALYQGISSLKKDVYIISKEDIPEDFKFLSCAGAITKSHGEVLDG
TELVIVLDCGNFARVNANIDIENKKYIFINIDHHISNELYGDYNFVDPNAACMGEIVYQMLKSLDVNINKDIATCLYTSI
LTDTGSFRHSNTTSVTHCVAGDLITTGIDFSSIHRKIFDNKNFIRFKLYGEVFNDMELIEDEICVMKVTQEMFKKFNIDS
GEDTSDIVSFGGTMKEVDVTLLLKEKDEEIKISLRSKSKADVRNVAEKLGGGGHIRAAGASVKGKTLEEVKNIAIDLIKK
ELMK
>Mature_324_residues
MKTMITNKILDLIMESNKIALTFHVSPDGDSIGSTLALYQGISSLKKDVYIISKEDIPEDFKFLSCAGAITKSHGEVLDG
TELVIVLDCGNFARVNANIDIENKKYIFINIDHHISNELYGDYNFVDPNAACMGEIVYQMLKSLDVNINKDIATCLYTSI
LTDTGSFRHSNTTSVTHCVAGDLITTGIDFSSIHRKIFDNKNFIRFKLYGEVFNDMELIEDEICVMKVTQEMFKKFNIDS
GEDTSDIVSFGGTMKEVDVTLLLKEKDEEIKISLRSKSKADVRNVAEKLGGGGHIRAAGASVKGKTLEEVKNIAIDLIKK
ELMK

Specific function: Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA oligonucleotides with a length of 5 nucleotides and shorter. Converts 3'(2')- phosphoadenosine 5'-phosphate (PAP) to AMP [H]

COG id: COG0618

COG function: function code R; Exopolyphosphatase-related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003156
- InterPro:   IPR001667 [H]

Pfam domain/function: PF01368 DHH; PF02272 DHHA1 [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 36020; Mature: 36020

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTMITNKILDLIMESNKIALTFHVSPDGDSIGSTLALYQGISSLKKDVYIISKEDIPED
CCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHH
FKFLSCAGAITKSHGEVLDGTELVIVLDCGNFARVNANIDIENKKYIFINIDHHISNELY
HHHHHHHHHHHCCCCCEECCCEEEEEEECCCEEEEEEEEEECCCEEEEEEECCHHCCCCC
GDYNFVDPNAACMGEIVYQMLKSLDVNINKDIATCLYTSILTDTGSFRHSNTTSVTHCVA
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
GDLITTGIDFSSIHRKIFDNKNFIRFKLYGEVFNDMELIEDEICVMKVTQEMFKKFNIDS
CCHHHCCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GEDTSDIVSFGGTMKEVDVTLLLKEKDEEIKISLRSKSKADVRNVAEKLGGGGHIRAAGA
CCCHHHHHHCCCCEEEEEEEEEEECCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEECCC
SVKGKTLEEVKNIAIDLIKKELMK
CCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTMITNKILDLIMESNKIALTFHVSPDGDSIGSTLALYQGISSLKKDVYIISKEDIPED
CCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHH
FKFLSCAGAITKSHGEVLDGTELVIVLDCGNFARVNANIDIENKKYIFINIDHHISNELY
HHHHHHHHHHHCCCCCEECCCEEEEEEECCCEEEEEEEEEECCCEEEEEEECCHHCCCCC
GDYNFVDPNAACMGEIVYQMLKSLDVNINKDIATCLYTSILTDTGSFRHSNTTSVTHCVA
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
GDLITTGIDFSSIHRKIFDNKNFIRFKLYGEVFNDMELIEDEICVMKVTQEMFKKFNIDS
CCHHHCCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GEDTSDIVSFGGTMKEVDVTLLLKEKDEEIKISLRSKSKADVRNVAEKLGGGGHIRAAGA
CCCHHHHHHCCCCEEEEEEEEEEECCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEECCC
SVKGKTLEEVKNIAIDLIKKELMK
CCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]