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The map label for this gene is frr

Identifier: 28210950

GI number: 28210950

Start: 1353778

End: 1354329

Strand: Direct

Name: frr

Synonym: CTC01264

Alternate gene names: 28210950

Gene position: 1353778-1354329 (Clockwise)

Preceding gene: 28210949

Following gene: 28210951

Centisome position: 48.36

GC content: 28.62

Gene sequence:

>552_bases
ATGTTAAAAGAAATAATGAATACAGCTGAAGACAAAATGAGTAAGGCTTTATTAGCTTTAAAGAAAGACTTAGCCTCATT
AAAGGCTGGAAGAGCAAATCCTGCTATGCTAGATAAAATAGAAGCAGAATATTATGGGACTATGACCCCTCTAAGTCAAC
TTGCTAATATATCTGTTCCGGAAGCAAGAATACTTCAAATACAACCTTGGGACAAATCTTCACTTAAAGCAATTGAAAAA
GCTATACTTGTATCAGATTTAGGATTAAATCCTAATAATGATGGAACTATTATTAGATTGATTATACCTGAACTTACAGA
AGAAACAAGAAGAAATATAGTAAAAACCGTAAAAAAATATGGAGAAGATACTAAAATAGCTATAAGATCTGTAAGAAGAG
ATGGTAATGATAAGATAAAGGATTTAAAATCCGATATGTCAGAAGATGATATCAAGAAAGCAGAAGAAGAAATTCAAAAA
ATAACAGATAATTATGTAAAAAAAGTAGATGAAATGATAGATATAAAAGAAAAAGAAATTATGTCTATTTAA

Upstream 100 bases:

>100_bases
TACTAGTTTTTGCCTTAGATGCTCCAGGTAATATAAGAAAAGCTATTTCTGGAGAAAAAATAGGAACTATAGTATGTAAG
GAATAAAGGGAGGAGTTTTT

Downstream 100 bases:

>100_bases
TAAAGAGTAAAGCCTGCGTTACCGCAGGTTTTATTAATAAGTTTTAGGGATGGAGATTTAAATGTGGAATATATTTAAAA
ATAAAAGTGGACAAAGCCAT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MLKEIMNTAEDKMSKALLALKKDLASLKAGRANPAMLDKIEAEYYGTMTPLSQLANISVPEARILQIQPWDKSSLKAIEK
AILVSDLGLNPNNDGTIIRLIIPELTEETRRNIVKTVKKYGEDTKIAIRSVRRDGNDKIKDLKSDMSEDDIKKAEEEIQK
ITDNYVKKVDEMIDIKEKEIMSI

Sequences:

>Translated_183_residues
MLKEIMNTAEDKMSKALLALKKDLASLKAGRANPAMLDKIEAEYYGTMTPLSQLANISVPEARILQIQPWDKSSLKAIEK
AILVSDLGLNPNNDGTIIRLIIPELTEETRRNIVKTVKKYGEDTKIAIRSVRRDGNDKIKDLKSDMSEDDIKKAEEEIQK
ITDNYVKKVDEMIDIKEKEIMSI
>Mature_183_residues
MLKEIMNTAEDKMSKALLALKKDLASLKAGRANPAMLDKIEAEYYGTMTPLSQLANISVPEARILQIQPWDKSSLKAIEK
AILVSDLGLNPNNDGTIIRLIIPELTEETRRNIVKTVKKYGEDTKIAIRSVRRDGNDKIKDLKSDMSEDDIKKAEEEIQK
ITDNYVKKVDEMIDIKEKEIMSI

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=185, Percent_Identity=31.3513513513514, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI291042689, Length=148, Percent_Identity=33.1081081081081, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1786368, Length=185, Percent_Identity=44.8648648648649, Blast_Score=169, Evalue=8e-44,
Organism=Drosophila melanogaster, GI24661488, Length=190, Percent_Identity=29.4736842105263, Blast_Score=74, Evalue=6e-14,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_CLOTE (Q895K9)

Other databases:

- EMBL:   AE015927
- RefSeq:   NP_781894.1
- ProteinModelPortal:   Q895K9
- SMR:   Q895K9
- GeneID:   1059346
- GenomeReviews:   AE015927_GR
- KEGG:   ctc:CTC01264
- NMPDR:   fig|212717.1.peg.1116
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   Q895K9
- ProtClustDB:   PRK00083
- BioCyc:   CTET212717:CTC_01264-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20703; Mature: 20703

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKEIMNTAEDKMSKALLALKKDLASLKAGRANPAMLDKIEAEYYGTMTPLSQLANISVP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCC
EARILQIQPWDKSSLKAIEKAILVSDLGLNPNNDGTIIRLIIPELTEETRRNIVKTVKKY
CCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHH
GEDTKIAIRSVRRDGNDKIKDLKSDMSEDDIKKAEEEIQKITDNYVKKVDEMIDIKEKEI
CCCHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSI
HCC
>Mature Secondary Structure
MLKEIMNTAEDKMSKALLALKKDLASLKAGRANPAMLDKIEAEYYGTMTPLSQLANISVP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCC
EARILQIQPWDKSSLKAIEKAILVSDLGLNPNNDGTIIRLIIPELTEETRRNIVKTVKKY
CCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHH
GEDTKIAIRSVRRDGNDKIKDLKSDMSEDDIKKAEEEIQKITDNYVKKVDEMIDIKEKEI
CCCHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSI
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12552129