Click here to switch to the map view.

The map label for this gene is codY

Identifier: 28210946

GI number: 28210946

Start: 1350208

End: 1350984

Strand: Direct

Name: codY

Synonym: CTC01260

Alternate gene names: 28210946

Gene position: 1350208-1350984 (Clockwise)

Preceding gene: 28210945

Following gene: 28210947

Centisome position: 48.23

GC content: 30.63

Gene sequence:

>777_bases
ATGTCATCATTATTAGAGAAGACAAGACAACTAAACAAAATATTACAAAAATCTGGAGCAGAACCTGTGGTGTTTGACGA
TATATGTAATCTTTTAAGTGAAGTGTTATCTTGTAATGTTTATATAATAAGTAAGAAAGGCAAAATATTGGGATATGATC
TTTCTACAGGATTTGAATGCCAGACAGTAAGAGACAAGGTAGTACCAGAAAAAAGATTCCCAGAACATTACAACAATAAA
TTATTGAATGTTCATGGAACTAAGTCAAATTTAGAAAATCAAGGAGAATGTGTTTTTGAATCAGGAGAAGATTGTGGTGT
AAAAAATAAACTTACCACAATTGTACCTATTAACGGTAATAGGGAAAGATTAGGTACACTTTTATTAGCTAGATTTGATG
TACCTTTTACTGATGATGATCTAATTATTTCTGAATACAGTGCTACTATAATAGGATTAGAAATACTAAGATCTAAGCAA
GATGAAATAGAGGAAGAAGCAAGAAAGAAAGCAGTAGTTCAATTAGCAATAGGAACTCTTTCATACTCTGAATTAGAGGC
AGTAGAACATATTTTTAATGAATTAGATGGGCCAGAAGGTCTATTAGTTGCCTCAAAAATAGCAGATAAAGTAGGAATAA
CTAGATCTGTGATAGTAAATGCATTAAGAAAATTTGAAAGTGCAGGAGTAATAGAATCTAGATCTTTAGGTATGAAGGGA
ACGCATATAAAGATATTAAACGACAGACTTTTAGAGGAATTGAAAAAAATTAAGTAA

Upstream 100 bases:

>100_bases
ATAAAATGTGGTTAGCATATAGTGGTTATACATAGATAGTAATAAAATTAAGAAGAGAAATTGCCCTATTAACAATAGAT
AAATAGAGGAGGAGTTACAA

Downstream 100 bases:

>100_bases
TTTAAGGATACTTTTAAAAGTATCCCTTTTTTAGTATATGCTGTTTATGAATAATATTTTTCCAAAAAAATTATTGAATA
CATGGAAAGCATATGATATA

Product: transcriptional repressor CodY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSSLLEKTRQLNKILQKSGAEPVVFDDICNLLSEVLSCNVYIISKKGKILGYDLSTGFECQTVRDKVVPEKRFPEHYNNK
LLNVHGTKSNLENQGECVFESGEDCGVKNKLTTIVPINGNRERLGTLLLARFDVPFTDDDLIISEYSATIIGLEILRSKQ
DEIEEEARKKAVVQLAIGTLSYSELEAVEHIFNELDGPEGLLVASKIADKVGITRSVIVNALRKFESAGVIESRSLGMKG
THIKILNDRLLEELKKIK

Sequences:

>Translated_258_residues
MSSLLEKTRQLNKILQKSGAEPVVFDDICNLLSEVLSCNVYIISKKGKILGYDLSTGFECQTVRDKVVPEKRFPEHYNNK
LLNVHGTKSNLENQGECVFESGEDCGVKNKLTTIVPINGNRERLGTLLLARFDVPFTDDDLIISEYSATIIGLEILRSKQ
DEIEEEARKKAVVQLAIGTLSYSELEAVEHIFNELDGPEGLLVASKIADKVGITRSVIVNALRKFESAGVIESRSLGMKG
THIKILNDRLLEELKKIK
>Mature_257_residues
SSLLEKTRQLNKILQKSGAEPVVFDDICNLLSEVLSCNVYIISKKGKILGYDLSTGFECQTVRDKVVPEKRFPEHYNNKL
LNVHGTKSNLENQGECVFESGEDCGVKNKLTTIVPINGNRERLGTLLLARFDVPFTDDDLIISEYSATIIGLEILRSKQD
EIEEEARKKAVVQLAIGTLSYSELEAVEHIFNELDGPEGLLVASKIADKVGITRSVIVNALRKFESAGVIESRSLGMKGT
HIKILNDRLLEELKKIK

Specific function: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of

COG id: COG4465

COG function: function code K; Pleiotropic transcriptional repressor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CodY family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CODY_CLOTE (Q895L3)

Other databases:

- EMBL:   AE015927
- RefSeq:   NP_781890.1
- ProteinModelPortal:   Q895L3
- GeneID:   1059350
- GenomeReviews:   AE015927_GR
- KEGG:   ctc:CTC01260
- NMPDR:   fig|212717.1.peg.1112
- HOGENOM:   HBG304760
- OMA:   HIFEELD
- ProtClustDB:   PRK04158
- BioCyc:   CTET212717:CTC_01260-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- HAMAP:   MF_00621
- InterPro:   IPR014154
- InterPro:   IPR010312
- InterPro:   IPR013198
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF011572
- TIGRFAMs:   TIGR02787

Pfam domain/function: PF06018 CodY; PF08222 HTH_CodY

EC number: NA

Molecular weight: Translated: 28732; Mature: 28601

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLLEKTRQLNKILQKSGAEPVVFDDICNLLSEVLSCNVYIISKKGKILGYDLSTGFEC
CCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCCH
QTVRDKVVPEKRFPEHYNNKLLNVHGTKSNLENQGECVFESGEDCGVKNKLTTIVPINGN
HHHHHHCCCCCCCCHHHCCCEEEEECCCCCCCCCCCEEEECCCCCCCCCCCEEEEECCCC
RERLGTLLLARFDVPFTDDDLIISEYSATIIGLEILRSKQDEIEEEARKKAVVQLAIGTL
HHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHC
SYSELEAVEHIFNELDGPEGLLVASKIADKVGITRSVIVNALRKFESAGVIESRSLGMKG
CHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHCCCEECCCCCCCC
THIKILNDRLLEELKKIK
CEEEEHHHHHHHHHHHCC
>Mature Secondary Structure 
SSLLEKTRQLNKILQKSGAEPVVFDDICNLLSEVLSCNVYIISKKGKILGYDLSTGFEC
CHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCCH
QTVRDKVVPEKRFPEHYNNKLLNVHGTKSNLENQGECVFESGEDCGVKNKLTTIVPINGN
HHHHHHCCCCCCCCHHHCCCEEEEECCCCCCCCCCCEEEECCCCCCCCCCCEEEEECCCC
RERLGTLLLARFDVPFTDDDLIISEYSATIIGLEILRSKQDEIEEEARKKAVVQLAIGTL
HHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHC
SYSELEAVEHIFNELDGPEGLLVASKIADKVGITRSVIVNALRKFESAGVIESRSLGMKG
CHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHCCCEECCCCCCCC
THIKILNDRLLEELKKIK
CEEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12552129