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The map label for this gene is coaD [H]

Identifier: 28210921

GI number: 28210921

Start: 1321775

End: 1322302

Strand: Direct

Name: coaD [H]

Synonym: CTC01234

Alternate gene names: 28210921

Gene position: 1321775-1322302 (Clockwise)

Preceding gene: 28210920

Following gene: 28210922

Centisome position: 47.22

GC content: 29.17

Gene sequence:

>528_bases
ATGGAAATACCACAGTATGCTTTTATAGACATAAGGAGGATTAAAATGAATATTGCAGTGTATCCAGGAAGTTTTGATCC
TATAACTAATGGACATTTAGACATAATTAAAAGAGCTTCCCAAGTTTTTGATAAAGTAGTAGTAGGAATTTTAGTAAATC
CAGATAAAAAAGGATTATTTTCTATAGAGGAAAGAGAAAAATTAATATCAAGAGTAGTAAAGGATATGCCTAATGTTGAA
GTTAGAAGTTTTAGTGGACTTTTAGTGGATTTTATGAAGGAAGAAAATATTAAGGTCATTATAAAGGGGTTAAGGGCTAT
GTCAGATTTTGAATATGAATTTCAAATGGCTCTTATGAATAAAAAGTTAAATCCAGATATAGAAACCTTATTTATGATGA
CTTGTGCTCAATACTCTTATTTAAGTTCTTCATCAATAAAGCAAGTTGCTATGTTTGGAGGATGCATAAAAGGGCTTGTA
CCTGATGAAATAATAGAGGATATATGTAAGAAGTCAAATAATAAATAG

Upstream 100 bases:

>100_bases
AACCTTTTAAAAGAGGATGGTATTATATCTATAAAAATTGATTCAAAAGAGGAAATATTTGAGGGTAGTGAGCATATTAA
ACTAGTAAGAATTAAAAGAT

Downstream 100 bases:

>100_bases
GAGGTGCTTTAATGGATGTAATAAAGCTCTTAGAATATCTACAAGATATCATAGAAACTTCTTCTAAGGTTCCTATGACA
GGAAGGGTAGTTGTAGATAG

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MEIPQYAFIDIRRIKMNIAVYPGSFDPITNGHLDIIKRASQVFDKVVVGILVNPDKKGLFSIEEREKLISRVVKDMPNVE
VRSFSGLLVDFMKEENIKVIIKGLRAMSDFEYEFQMALMNKKLNPDIETLFMMTCAQYSYLSSSSIKQVAMFGGCIKGLV
PDEIIEDICKKSNNK

Sequences:

>Translated_175_residues
MEIPQYAFIDIRRIKMNIAVYPGSFDPITNGHLDIIKRASQVFDKVVVGILVNPDKKGLFSIEEREKLISRVVKDMPNVE
VRSFSGLLVDFMKEENIKVIIKGLRAMSDFEYEFQMALMNKKLNPDIETLFMMTCAQYSYLSSSSIKQVAMFGGCIKGLV
PDEIIEDICKKSNNK
>Mature_175_residues
MEIPQYAFIDIRRIKMNIAVYPGSFDPITNGHLDIIKRASQVFDKVVVGILVNPDKKGLFSIEEREKLISRVVKDMPNVE
VRSFSGLLVDFMKEENIKVIIKGLRAMSDFEYEFQMALMNKKLNPDIETLFMMTCAQYSYLSSSSIKQVAMFGGCIKGLV
PDEIIEDICKKSNNK

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=153, Percent_Identity=43.7908496732026, Blast_Score=162, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 19955; Mature: 19955

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIPQYAFIDIRRIKMNIAVYPGSFDPITNGHLDIIKRASQVFDKVVVGILVNPDKKGLF
CCCCCHHHHEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCC
SIEEREKLISRVVKDMPNVEVRSFSGLLVDFMKEENIKVIIKGLRAMSDFEYEFQMALMN
CHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHC
KKLNPDIETLFMMTCAQYSYLSSSSIKQVAMFGGCIKGLVPDEIIEDICKKSNNK
CCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MEIPQYAFIDIRRIKMNIAVYPGSFDPITNGHLDIIKRASQVFDKVVVGILVNPDKKGLF
CCCCCHHHHEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCC
SIEEREKLISRVVKDMPNVEVRSFSGLLVDFMKEENIKVIIKGLRAMSDFEYEFQMALMN
CHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHC
KKLNPDIETLFMMTCAQYSYLSSSSIKQVAMFGGCIKGLVPDEIIEDICKKSNNK
CCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]