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The map label for this gene is rsmB [H]

Identifier: 28210910

GI number: 28210910

Start: 1309202

End: 1310566

Strand: Direct

Name: rsmB [H]

Synonym: CTC01222

Alternate gene names: 28210910

Gene position: 1309202-1310566 (Clockwise)

Preceding gene: 28210909

Following gene: 28210911

Centisome position: 46.77

GC content: 26.74

Gene sequence:

>1365_bases
TTGTGTATAAATATAAAAAATAGGAGAAATTTATATATGGTAACAGATAGAAAAGTAGCTATAGAAGTGTTAGATGCAGT
GTTTCTTAAAAATGCCTACTCTAATATAGCCCTAAATAATGCCTTAAATAAATACAAGCTAAATGAGAAGGATAAAGCTT
TTATAACAGAATTGGTATATGGAACTATAAAATATAGGCACACCATAGATACTATATTAAATAGTTACATAAAAAAGGGA
ATAAAAAGTGTAGACAAATATGTTTTAAATATATTGAGAATAGGTATTTACCAACTAAGGTACCTTGATAAAGTTCCTAG
TTTTGCAGCAGTAAATGAGTGTGTAGAACTAGGAAAAGTAAAGTCAAAAGGGACTGGTAAACTGATAAATGGAGTTTTAA
GAAACTACATAAGAAATAAAGATCCTAAATACTATGATGAAAGTAATTTAGTAGAAAAATTATCCTTTGAATATTCCTAT
CCAAAGTGGATGATAGACTTATTTTTAAAACAATATGGTAGAGAAAAGATAGAAGAAATATTAAAAGGGTTAAATTCTAT
ACCTTCAATTACAGTTAGGGTTAACAATATTAAAAGTGATTATGAAAGTGTATGGAATTCATTAGAAGATAATAATTACA
ATATAGAAGAAGGTTTGGTTTGTCCTGAAGCTATAAGAATAATTAAAGGAAGAGCCATAGAAAAAAATCCTCTTTTTAAA
GAAGGACTTATAACAGTACAGGATGAAAGTGCTATGCTTGTGGCAGGAGCTATGGATTTAGAAGATAATATGAATGTAAT
GGATCTTTGTAGTGCTCCCGGGGGTAAAACTACACATATATCAGAAATAATGAATAATACTGGCAAGGTGTTAGCTTTTG
ATATACATGAAAACAAATTGGATCTAATTAAACAAAATAAAGAACGTTTAGGAGTTAAGAATATAGATCTTATACTAGGA
GATGGAACTTTATATAATAAAAAGTATAGTGAATTTGCAAATAGAATTTTAATAGATGCTCCTTGTTCAGGGTTAGGTAT
TATTAGAAAAAAACCTGAAATAAAATATACTAAAAGTGCTAAGGATTTAAAATCTATAGTTCATATTCAAAGAAAAATAT
TAGAAAATGGGGCTAAGTATCTTAAAAAGAATGGAATACTCTTATATTCAACTTGTACATTAAATAAAAAAGAAAATATA
GAAAATGTTAAATGGTTTTTAAAAGAGTTTCCTAACTTTAAAATTGAAAAAATCTTTTTAGGTAATTTAGACAATTTTAT
ATATGATGAATATGGTACACTTACCATATTACCAAATGAATATATGGATGGATTTTATATAGCCAAATTTAAAAAACAGC
GGTAG

Upstream 100 bases:

>100_bases
CTCTAACGGCTATCTCTCAACTTTTAAGACTTATTGTTTTAAGTAGAAGAAATGATTAGTAAAAAAGCTGTATGGCACAA
ATACATGCCATACAACTTTC

Downstream 100 bases:

>100_bases
GTGTTTAATATGATAAATTTATTAGACTTAAGCTTAGAGGATTTAAAAAAGTGGATGATAGAAAATAAAGAAAAAGAATT
TAGAGCAAAACAAGTATTAG

Product: 16S rRNA M(5)C 967 methyltransferase

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MCINIKNRRNLYMVTDRKVAIEVLDAVFLKNAYSNIALNNALNKYKLNEKDKAFITELVYGTIKYRHTIDTILNSYIKKG
IKSVDKYVLNILRIGIYQLRYLDKVPSFAAVNECVELGKVKSKGTGKLINGVLRNYIRNKDPKYYDESNLVEKLSFEYSY
PKWMIDLFLKQYGREKIEEILKGLNSIPSITVRVNNIKSDYESVWNSLEDNNYNIEEGLVCPEAIRIIKGRAIEKNPLFK
EGLITVQDESAMLVAGAMDLEDNMNVMDLCSAPGGKTTHISEIMNNTGKVLAFDIHENKLDLIKQNKERLGVKNIDLILG
DGTLYNKKYSEFANRILIDAPCSGLGIIRKKPEIKYTKSAKDLKSIVHIQRKILENGAKYLKKNGILLYSTCTLNKKENI
ENVKWFLKEFPNFKIEKIFLGNLDNFIYDEYGTLTILPNEYMDGFYIAKFKKQR

Sequences:

>Translated_454_residues
MCINIKNRRNLYMVTDRKVAIEVLDAVFLKNAYSNIALNNALNKYKLNEKDKAFITELVYGTIKYRHTIDTILNSYIKKG
IKSVDKYVLNILRIGIYQLRYLDKVPSFAAVNECVELGKVKSKGTGKLINGVLRNYIRNKDPKYYDESNLVEKLSFEYSY
PKWMIDLFLKQYGREKIEEILKGLNSIPSITVRVNNIKSDYESVWNSLEDNNYNIEEGLVCPEAIRIIKGRAIEKNPLFK
EGLITVQDESAMLVAGAMDLEDNMNVMDLCSAPGGKTTHISEIMNNTGKVLAFDIHENKLDLIKQNKERLGVKNIDLILG
DGTLYNKKYSEFANRILIDAPCSGLGIIRKKPEIKYTKSAKDLKSIVHIQRKILENGAKYLKKNGILLYSTCTLNKKENI
ENVKWFLKEFPNFKIEKIFLGNLDNFIYDEYGTLTILPNEYMDGFYIAKFKKQR
>Mature_454_residues
MCINIKNRRNLYMVTDRKVAIEVLDAVFLKNAYSNIALNNALNKYKLNEKDKAFITELVYGTIKYRHTIDTILNSYIKKG
IKSVDKYVLNILRIGIYQLRYLDKVPSFAAVNECVELGKVKSKGTGKLINGVLRNYIRNKDPKYYDESNLVEKLSFEYSY
PKWMIDLFLKQYGREKIEEILKGLNSIPSITVRVNNIKSDYESVWNSLEDNNYNIEEGLVCPEAIRIIKGRAIEKNPLFK
EGLITVQDESAMLVAGAMDLEDNMNVMDLCSAPGGKTTHISEIMNNTGKVLAFDIHENKLDLIKQNKERLGVKNIDLILG
DGTLYNKKYSEFANRILIDAPCSGLGIIRKKPEIKYTKSAKDLKSIVHIQRKILENGAKYLKKNGILLYSTCTLNKKENI
ENVKWFLKEFPNFKIEKIFLGNLDNFIYDEYGTLTILPNEYMDGFYIAKFKKQR

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=348, Percent_Identity=29.5977011494253, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI76150623, Length=348, Percent_Identity=29.5977011494253, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI32698918, Length=183, Percent_Identity=37.7049180327869, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI8922322, Length=291, Percent_Identity=24.7422680412371, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI270288818, Length=291, Percent_Identity=24.7422680412371, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI23199998, Length=287, Percent_Identity=25.0871080139373, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI270288816, Length=287, Percent_Identity=25.0871080139373, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI39995082, Length=177, Percent_Identity=29.9435028248588, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI301336155, Length=177, Percent_Identity=29.9435028248588, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI11545785, Length=218, Percent_Identity=25.6880733944954, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI2367212, Length=458, Percent_Identity=30.1310043668122, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI87081985, Length=219, Percent_Identity=35.1598173515982, Blast_Score=144, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17536757, Length=343, Percent_Identity=28.8629737609329, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI115534021, Length=168, Percent_Identity=31.547619047619, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71998419, Length=170, Percent_Identity=31.7647058823529, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25143471, Length=271, Percent_Identity=25.0922509225092, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324268, Length=311, Percent_Identity=27.3311897106109, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6319447, Length=199, Percent_Identity=29.1457286432161, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI22024126, Length=316, Percent_Identity=29.4303797468354, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24668781, Length=242, Percent_Identity=28.9256198347107, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21356513, Length=242, Percent_Identity=28.9256198347107, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21356579, Length=229, Percent_Identity=26.2008733624454, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21355201, Length=176, Percent_Identity=30.1136363636364, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 52299; Mature: 52299

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCINIKNRRNLYMVTDRKVAIEVLDAVFLKNAYSNIALNNALNKYKLNEKDKAFITELVY
CEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHHH
GTIKYRHTIDTILNSYIKKGIKSVDKYVLNILRIGIYQLRYLDKVPSFAAVNECVELGKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
KSKGTGKLINGVLRNYIRNKDPKYYDESNLVEKLSFEYSYPKWMIDLFLKQYGREKIEEI
CCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHH
LKGLNSIPSITVRVNNIKSDYESVWNSLEDNNYNIEEGLVCPEAIRIIKGRAIEKNPLFK
HHHHCCCCEEEEEEECCHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHCCCCCCCCCHH
EGLITVQDESAMLVAGAMDLEDNMNVMDLCSAPGGKTTHISEIMNNTGKVLAFDIHENKL
HCCEEEECCCEEEEEECCCCCCCCCHHHHHCCCCCCCHHHHHHHCCCCCEEEEEECCCHH
DLIKQNKERLGVKNIDLILGDGTLYNKKYSEFANRILIDAPCSGLGIIRKKPEIKYTKSA
HHHHCCHHHCCCCCEEEEEECCCCCCCHHHHHHCEEEEECCCCCCCCCCCCCCCCCCCCH
KDLKSIVHIQRKILENGAKYLKKNGILLYSTCTLNKKENIENVKWFLKEFPNFKIEKIFL
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEE
GNLDNFIYDEYGTLTILPNEYMDGFYIAKFKKQR
CCCCHHHCCCCCEEEECCHHHCCCEEEEEEECCC
>Mature Secondary Structure
MCINIKNRRNLYMVTDRKVAIEVLDAVFLKNAYSNIALNNALNKYKLNEKDKAFITELVY
CEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHHH
GTIKYRHTIDTILNSYIKKGIKSVDKYVLNILRIGIYQLRYLDKVPSFAAVNECVELGKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
KSKGTGKLINGVLRNYIRNKDPKYYDESNLVEKLSFEYSYPKWMIDLFLKQYGREKIEEI
CCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHH
LKGLNSIPSITVRVNNIKSDYESVWNSLEDNNYNIEEGLVCPEAIRIIKGRAIEKNPLFK
HHHHCCCCEEEEEEECCHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHCCCCCCCCCHH
EGLITVQDESAMLVAGAMDLEDNMNVMDLCSAPGGKTTHISEIMNNTGKVLAFDIHENKL
HCCEEEECCCEEEEEECCCCCCCCCHHHHHCCCCCCCHHHHHHHCCCCCEEEEEECCCHH
DLIKQNKERLGVKNIDLILGDGTLYNKKYSEFANRILIDAPCSGLGIIRKKPEIKYTKSA
HHHHCCHHHCCCCCEEEEEECCCCCCCHHHHHHCEEEEECCCCCCCCCCCCCCCCCCCCH
KDLKSIVHIQRKILENGAKYLKKNGILLYSTCTLNKKENIENVKWFLKEFPNFKIEKIFL
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEE
GNLDNFIYDEYGTLTILPNEYMDGFYIAKFKKQR
CCCCHHHCCCCCEEEECCHHHCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]