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The map label for this gene is engA

Identifier: 28210831

GI number: 28210831

Start: 1202609

End: 1203925

Strand: Direct

Name: engA

Synonym: CTC01137

Alternate gene names: 28210831

Gene position: 1202609-1203925 (Clockwise)

Preceding gene: 28210830

Following gene: 161486845

Centisome position: 42.96

GC content: 30.75

Gene sequence:

>1317_bases
ATGGGAAAACCAATAGTTGCAATAGTAGGAAGACCAAATGTAGGAAAATCTACACTATTTAATAAACTAGCAGGAAAAAG
AATTGCTATAGTAGAGGATACACCAGGAGTTACAAGAGATAGAATATATGCTCAAGCGGAGTGGTTAAATCACAATTTTA
CAATAATAGATACAGGTGGTATAGAGCCAGAAAGCGAAGATATAATAGTAGCTCAAATGAGAAGACAGGCAGAAATGGCA
ATAGAAATGGCAGATGTAATAATGTTTATAGTAGACGGTAAAGAAGGATTAACACCGGCTGATAATGAAGTAGCCCTAAT
GCTTAGAAAAAGTAAAAAACCAATAGTATTAGTAGTAAATAAAATAGACAGAATAGAAGAAGAAGATAATATGTATGAAT
TCTATAATTTAGGTATAGGAGAACCTACAACTATTTCAGCTTCTCAAGCTTTAGGACTAGGAGATATGCTAGATAAAATA
GTAGAAAATTTTCCAAAAGGTTATCAAGATGAAGAAGAGGATGAGTATATTAGAATAGCCTTTGTTGGAAAACCAAATGT
AGGAAAGTCTTCTCTTATAAATAAGATATTAGGAGAGGAAAGAAATATAGTAAGTAATATACCAGGAACTACAAGAGATG
CTATAGATAGTTTTCTAGAAAGAGATGAAGATAAATTTATATTAATAGATACAGCAGGGCTTAGAAGAAGAAGTAAGGTA
AAGGATCAAATAGAAAGATATAGTACAGTAAGAACCTATGCTGCTATAGATAGAGCAGATGTATGTATACTTTTAATAGA
TGCAGAAGAGGGAATAAGTGAACAAGATAAAAAAATAATAGGATATGCACATGAATTGAATAAAGCATTAATGGTAGTTG
TAAATAAGTGGGATTTAATAGAAAAAGAAACAAATACCATGAATAGATTTAAAAAAGAACTTCAAAGTGAGCTTTCTTTT
ATGAGTTATGCTCCTTATATTTTCATATCAGCTAAAACAGGACAGAGAGTAGGAAAGGTTTTAGATTTAGCTAAAGAATG
TTATACCAATTATAGTAAAAGAATAAGTACGGGCGTTTTAAATGATGTTATAAGTAAGGCAGTAATGATGAAGGAACCAC
CAATAGTTGCCATGAATAGATTAAAAATATATTATGTTACTCAAGTTGCTACAAAAGCACCAACTTTTGTATTCTTCGTA
AATGATCCTAGAACATTACATTTCTCCTATGAAAGGTATTTAGAAAATCAACTAAGACAAAGCTTTGATTTTACAGGAAC
AGGAATTAAAATGGAGTTTAGAGAAAGGAAAGAGTAA

Upstream 100 bases:

>100_bases
AGAATTAGAAGAGTTTTATGGTAAAAGTATAATTATATGTGAGTATACAGGAGAGGATTTTATAGAAATACTAAATGAAT
ACAGCAAGGAGGAAAATTAA

Downstream 100 bases:

>100_bases
TATGACAATTAAAGGTATAACTTTTATTGGAGGAGGAAGTTTTGGTACTGCTTTAGGTATTATGTTAGCCAAAAAGGGTT
ATAACATAAATATATGGGAT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MGKPIVAIVGRPNVGKSTLFNKLAGKRIAIVEDTPGVTRDRIYAQAEWLNHNFTIIDTGGIEPESEDIIVAQMRRQAEMA
IEMADVIMFIVDGKEGLTPADNEVALMLRKSKKPIVLVVNKIDRIEEEDNMYEFYNLGIGEPTTISASQALGLGDMLDKI
VENFPKGYQDEEEDEYIRIAFVGKPNVGKSSLINKILGEERNIVSNIPGTTRDAIDSFLERDEDKFILIDTAGLRRRSKV
KDQIERYSTVRTYAAIDRADVCILLIDAEEGISEQDKKIIGYAHELNKALMVVVNKWDLIEKETNTMNRFKKELQSELSF
MSYAPYIFISAKTGQRVGKVLDLAKECYTNYSKRISTGVLNDVISKAVMMKEPPIVAMNRLKIYYVTQVATKAPTFVFFV
NDPRTLHFSYERYLENQLRQSFDFTGTGIKMEFRERKE

Sequences:

>Translated_438_residues
MGKPIVAIVGRPNVGKSTLFNKLAGKRIAIVEDTPGVTRDRIYAQAEWLNHNFTIIDTGGIEPESEDIIVAQMRRQAEMA
IEMADVIMFIVDGKEGLTPADNEVALMLRKSKKPIVLVVNKIDRIEEEDNMYEFYNLGIGEPTTISASQALGLGDMLDKI
VENFPKGYQDEEEDEYIRIAFVGKPNVGKSSLINKILGEERNIVSNIPGTTRDAIDSFLERDEDKFILIDTAGLRRRSKV
KDQIERYSTVRTYAAIDRADVCILLIDAEEGISEQDKKIIGYAHELNKALMVVVNKWDLIEKETNTMNRFKKELQSELSF
MSYAPYIFISAKTGQRVGKVLDLAKECYTNYSKRISTGVLNDVISKAVMMKEPPIVAMNRLKIYYVTQVATKAPTFVFFV
NDPRTLHFSYERYLENQLRQSFDFTGTGIKMEFRERKE
>Mature_437_residues
GKPIVAIVGRPNVGKSTLFNKLAGKRIAIVEDTPGVTRDRIYAQAEWLNHNFTIIDTGGIEPESEDIIVAQMRRQAEMAI
EMADVIMFIVDGKEGLTPADNEVALMLRKSKKPIVLVVNKIDRIEEEDNMYEFYNLGIGEPTTISASQALGLGDMLDKIV
ENFPKGYQDEEEDEYIRIAFVGKPNVGKSSLINKILGEERNIVSNIPGTTRDAIDSFLERDEDKFILIDTAGLRRRSKVK
DQIERYSTVRTYAAIDRADVCILLIDAEEGISEQDKKIIGYAHELNKALMVVVNKWDLIEKETNTMNRFKKELQSELSFM
SYAPYIFISAKTGQRVGKVLDLAKECYTNYSKRISTGVLNDVISKAVMMKEPPIVAMNRLKIYYVTQVATKAPTFVFFVN
DPRTLHFSYERYLENQLRQSFDFTGTGIKMEFRERKE

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=460, Percent_Identity=40.6521739130435, Blast_Score=348, Evalue=4e-97,
Organism=Escherichia coli, GI1788919, Length=126, Percent_Identity=38.0952380952381, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI2367268, Length=94, Percent_Identity=39.3617021276596, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17507259, Length=124, Percent_Identity=33.0645161290323, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=208, Percent_Identity=31.25, Blast_Score=94, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_CLOTE (Q895X8)

Other databases:

- EMBL:   AE015927
- RefSeq:   NP_781775.1
- ProteinModelPortal:   Q895X8
- SMR:   Q895X8
- GeneID:   1060702
- GenomeReviews:   AE015927_GR
- KEGG:   ctc:CTC01137
- NMPDR:   fig|212717.1.peg.997
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- PhylomeDB:   Q895X8
- ProtClustDB:   PRK00093
- BioCyc:   CTET212717:CTC_01137-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- SMART:   SM00382
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 49807; Mature: 49676

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKPIVAIVGRPNVGKSTLFNKLAGKRIAIVEDTPGVTRDRIYAQAEWLNHNFTIIDTGG
CCCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHEEEEEECCCCEEEEECCC
IEPESEDIIVAQMRRQAEMAIEMADVIMFIVDGKEGLTPADNEVALMLRKSKKPIVLVVN
CCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCEEEEEECCCCCEEEEEE
KIDRIEEEDNMYEFYNLGIGEPTTISASQALGLGDMLDKIVENFPKGYQDEEEDEYIRIA
CHHCCCCCCCEEEEEECCCCCCCEECHHHHCCHHHHHHHHHHHCCCCCCCCCCCCEEEEE
FVGKPNVGKSSLINKILGEERNIVSNIPGTTRDAIDSFLERDEDKFILIDTAGLRRRSKV
EECCCCCCHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHH
KDQIERYSTVRTYAAIDRADVCILLIDAEEGISEQDKKIIGYAHELNKALMVVVNKWDLI
HHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCEEEEEEECCHHH
EKETNTMNRFKKELQSELSFMSYAPYIFISAKTGQRVGKVLDLAKECYTNYSKRISTGVL
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NDVISKAVMMKEPPIVAMNRLKIYYVTQVATKAPTFVFFVNDPRTLHFSYERYLENQLRQ
HHHHHHHHHHCCCCEEEECCEEEEEEEEECCCCCEEEEEECCCEEEEEHHHHHHHHHHHH
SFDFTGTGIKMEFRERKE
HCCCCCCCEEEECCCCCC
>Mature Secondary Structure 
GKPIVAIVGRPNVGKSTLFNKLAGKRIAIVEDTPGVTRDRIYAQAEWLNHNFTIIDTGG
CCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHEEEEEECCCCEEEEECCC
IEPESEDIIVAQMRRQAEMAIEMADVIMFIVDGKEGLTPADNEVALMLRKSKKPIVLVVN
CCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCEEEEEECCCCCEEEEEE
KIDRIEEEDNMYEFYNLGIGEPTTISASQALGLGDMLDKIVENFPKGYQDEEEDEYIRIA
CHHCCCCCCCEEEEEECCCCCCCEECHHHHCCHHHHHHHHHHHCCCCCCCCCCCCEEEEE
FVGKPNVGKSSLINKILGEERNIVSNIPGTTRDAIDSFLERDEDKFILIDTAGLRRRSKV
EECCCCCCHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHH
KDQIERYSTVRTYAAIDRADVCILLIDAEEGISEQDKKIIGYAHELNKALMVVVNKWDLI
HHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCEEEEEEECCHHH
EKETNTMNRFKKELQSELSFMSYAPYIFISAKTGQRVGKVLDLAKECYTNYSKRISTGVL
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NDVISKAVMMKEPPIVAMNRLKIYYVTQVATKAPTFVFFVNDPRTLHFSYERYLENQLRQ
HHHHHHHHHHCCCCEEEECCEEEEEEEEECCCCCEEEEEECCCEEEEEHHHHHHHHHHHH
SFDFTGTGIKMEFRERKE
HCCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12552129