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The map label for this gene is cymR [H]

Identifier: 28210751

GI number: 28210751

Start: 1118697

End: 1119131

Strand: Direct

Name: cymR [H]

Synonym: CTC01049

Alternate gene names: 28210751

Gene position: 1118697-1119131 (Clockwise)

Preceding gene: 28210750

Following gene: 28210752

Centisome position: 39.96

GC content: 31.03

Gene sequence:

>435_bases
ATGAAATTATCTACAAAGGGGAGATATGGTGTAAGGGCTATGATAGACTTGGCTTTAAACTATGGAGATATCCCTATTTC
TATAAAAAGTATTTCAGAAAGACAAAATATATCAGAATATTATTTAGAACAATTATTTGCTACTTTAAGAAAAGCAGATT
TAATAAAAAGTATTAGAGGAGCTCAAGGTGGATACTTGTTAAGTAGGGAACCCAAGGATATAAGTATTGCAGAAATTATA
GAAACCTTAGAAGGACCTGTAGAACTATCTAACTGTGTATCACAAGGAGAGTGTGAAAATATGGACTCTTGTTCCACAAG
GTTATTGTGGGTAAGAATTAAAGAAAGTATTGATAATGTAACAAAGACTACAACACTTCAAGATATGGTAGATGACTATT
ATAAATTAAACAGTTGTAAAGGAAAGGGGAAATAA

Upstream 100 bases:

>100_bases
TTATAAATTTATAGTTGACAGGAATACTCGGATTTGTTATTATAAATTTGAAAGTTTAGTAAAGCAGTAGACTTTCATCG
GTAACTAGAGAGGTGATTAG

Downstream 100 bases:

>100_bases
AAATGGACAGAAAAGTTGTATATATGGATTACTCAGCTACTACATATACAAAGCCAGAGGTTTTAGAAGAAATGCTTCCT
TATTTTACAGGTAAATTTGG

Product: RRF2 family protein

Products: NA

Alternate protein names: Cysteine metabolism repressor [H]

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MKLSTKGRYGVRAMIDLALNYGDIPISIKSISERQNISEYYLEQLFATLRKADLIKSIRGAQGGYLLSREPKDISIAEII
ETLEGPVELSNCVSQGECENMDSCSTRLLWVRIKESIDNVTKTTTLQDMVDDYYKLNSCKGKGK

Sequences:

>Translated_144_residues
MKLSTKGRYGVRAMIDLALNYGDIPISIKSISERQNISEYYLEQLFATLRKADLIKSIRGAQGGYLLSREPKDISIAEII
ETLEGPVELSNCVSQGECENMDSCSTRLLWVRIKESIDNVTKTTTLQDMVDDYYKLNSCKGKGK
>Mature_144_residues
MKLSTKGRYGVRAMIDLALNYGDIPISIKSISERQNISEYYLEQLFATLRKADLIKSIRGAQGGYLLSREPKDISIAEII
ETLEGPVELSNCVSQGECENMDSCSTRLLWVRIKESIDNVTKTTTLQDMVDDYYKLNSCKGKGK

Specific function: Master repressor of cysteine metabolism in B.subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK), sulfonates (ssu), or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulate

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=132, Percent_Identity=40.9090909090909, Blast_Score=101, Evalue=2e-23,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000944 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 16193; Mature: 16193

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSTKGRYGVRAMIDLALNYGDIPISIKSISERQNISEYYLEQLFATLRKADLIKSIRG
CCCCCCCCCHHHHHHHHHHCCCCCCEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
AQGGYLLSREPKDISIAEIIETLEGPVELSNCVSQGECENMDSCSTRLLWVRIKESIDNV
CCCCEEECCCCCCCCHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
TKTTTLQDMVDDYYKLNSCKGKGK
HHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKLSTKGRYGVRAMIDLALNYGDIPISIKSISERQNISEYYLEQLFATLRKADLIKSIRG
CCCCCCCCCHHHHHHHHHHCCCCCCEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
AQGGYLLSREPKDISIAEIIETLEGPVELSNCVSQGECENMDSCSTRLLWVRIKESIDNV
CCCCEEECCCCCCCCHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
TKTTTLQDMVDDYYKLNSCKGKGK
HHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]