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The map label for this gene is focA [H]

Identifier: 28210634

GI number: 28210634

Start: 979678

End: 980580

Strand: Direct

Name: focA [H]

Synonym: CTC00923

Alternate gene names: 28210634

Gene position: 979678-980580 (Clockwise)

Preceding gene: 28210633

Following gene: 28210635

Centisome position: 35.0

GC content: 33.33

Gene sequence:

>903_bases
GTGAATACGAGAAATTACTTAACACCTGCAGAAATCGCTACTACAACGGTGGAAACAGGAGTAAAAAAGGCAAAACTTTC
ATTTTCACACCAGTTGATTTTAGGGATTTTAGCAGGAGCATTCATTGCATTTGCATCTGAAGGATCTAATATGGCAGCAT
TTAATTTATTTGAAAACCATGAAACCTATGGACTTGGAAAAGCTCTAGCTGGTTCAATGTTTGGTATAGGACTTATGCTA
GTTATTTTCGCAGGAGGAGAACTATTTACAGGAAATACATTGATTATTATAAGTGTTTTAGAAAAAAAAGTAACATTAAG
AGAAATGCTGAGAAATTGGTGTACTGTATATATGGGAAATCTAATAGGCTCTTTAATAATAGCCTTTATGATGGTAGAAT
CAGGATTATTTAATAGTGGAGCCCATATACTAGGTGGACAAACCATTAAAATTGCTGCTTACAAGGTTGGCTTATCTTTC
ATGCCTGCTCTGTATTTAGGAATTATGGCAAATTGGCTTATTGGCTTAGCTGTATGGTTAGCCCATGGAGCGAAAAGCAT
GGTAGGCAAGATTTTTGGAATATTCTGTCCAATAGGGCTTTTTGTCACATCTGGTTTTGAACAGAGCATTGCTAATATGT
ATTATATTCCTGCAGGAATATTAGCAAAATCAAATATTAATTGGGTCAATGCATCTAAGCTTTCACCAGAAGAGTTAGCC
AATTTAAATTGGAGTAATTTTATATTCAATAATTTAATACCTGTAACCCTTGGAAATATAATCGGTGGTGCTATATTTGT
AGGTCTTATATATTGGTTTGTCTATCTAAAACCTGATACATCACAAGTAATGGAAAATACAGTGGTAATAAATAATACAT
TGGAAAATGAAATCAATTTATAA

Upstream 100 bases:

>100_bases
TTATATGCATTTTACAGACGATTTATAGACAAGAAAGCATTATAATAGAATTAGATTATAATGCTTATATTAAGCAACTA
TAGTAAAAGGTGGTTATAAA

Downstream 100 bases:

>100_bases
ATATTAAAATATGAAATTAAATGCGTTGTAGATAGAATTAACATTCTTGAACCAACGCATTTTTTACATGCATGTTATTA
AGATGTAAAGGAATTCACAG

Product: putative formate transporter

Products: formate [Periplasm]; formate [Cytoplasm] [C]

Alternate protein names: Formate channel 1 [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MNTRNYLTPAEIATTTVETGVKKAKLSFSHQLILGILAGAFIAFASEGSNMAAFNLFENHETYGLGKALAGSMFGIGLML
VIFAGGELFTGNTLIIISVLEKKVTLREMLRNWCTVYMGNLIGSLIIAFMMVESGLFNSGAHILGGQTIKIAAYKVGLSF
MPALYLGIMANWLIGLAVWLAHGAKSMVGKIFGIFCPIGLFVTSGFEQSIANMYYIPAGILAKSNINWVNASKLSPEELA
NLNWSNFIFNNLIPVTLGNIIGGAIFVGLIYWFVYLKPDTSQVMENTVVINNTLENEINL

Sequences:

>Translated_300_residues
MNTRNYLTPAEIATTTVETGVKKAKLSFSHQLILGILAGAFIAFASEGSNMAAFNLFENHETYGLGKALAGSMFGIGLML
VIFAGGELFTGNTLIIISVLEKKVTLREMLRNWCTVYMGNLIGSLIIAFMMVESGLFNSGAHILGGQTIKIAAYKVGLSF
MPALYLGIMANWLIGLAVWLAHGAKSMVGKIFGIFCPIGLFVTSGFEQSIANMYYIPAGILAKSNINWVNASKLSPEELA
NLNWSNFIFNNLIPVTLGNIIGGAIFVGLIYWFVYLKPDTSQVMENTVVINNTLENEINL
>Mature_300_residues
MNTRNYLTPAEIATTTVETGVKKAKLSFSHQLILGILAGAFIAFASEGSNMAAFNLFENHETYGLGKALAGSMFGIGLML
VIFAGGELFTGNTLIIISVLEKKVTLREMLRNWCTVYMGNLIGSLIIAFMMVESGLFNSGAHILGGQTIKIAAYKVGLSF
MPALYLGIMANWLIGLAVWLAHGAKSMVGKIFGIFCPIGLFVTSGFEQSIANMYYIPAGILAKSNINWVNASKLSPEELA
NLNWSNFIFNNLIPVTLGNIIGGAIFVGLIYWFVYLKPDTSQVMENTVVINNTLENEINL

Specific function: Involved in the bidirectional transport of formate [H]

COG id: COG2116

COG function: function code P; Formate/nitrite family of transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FNT transporter (TC 2.A.44) family [H]

Homologues:

Organism=Escherichia coli, GI1787132, Length=290, Percent_Identity=36.2068965517241, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1788837, Length=272, Percent_Identity=30.1470588235294, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI87082249, Length=213, Percent_Identity=32.3943661971831, Blast_Score=83, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6321779, Length=286, Percent_Identity=30.0699300699301, Blast_Score=106, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000292 [H]

Pfam domain/function: PF01226 Form_Nir_trans [H]

EC number: NA

Molecular weight: Translated: 32546; Mature: 32546

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTRNYLTPAEIATTTVETGVKKAKLSFSHQLILGILAGAFIAFASEGSNMAAFNLFENH
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
ETYGLGKALAGSMFGIGLMLVIFAGGELFTGNTLIIISVLEKKVTLREMLRNWCTVYMGN
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEEEHHHHHHHHHHHHHHHHHHHHHH
LIGSLIIAFMMVESGLFNSGAHILGGQTIKIAAYKVGLSFMPALYLGIMANWLIGLAVWL
HHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
AHGAKSMVGKIFGIFCPIGLFVTSGFEQSIANMYYIPAGILAKSNINWVNASKLSPEELA
HHCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEEECCCCCEEECCCCEECCCCCCHHHHH
NLNWSNFIFNNLIPVTLGNIIGGAIFVGLIYWFVYLKPDTSQVMENTVVINNTLENEINL
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCEEEECCHHCCCCC
>Mature Secondary Structure
MNTRNYLTPAEIATTTVETGVKKAKLSFSHQLILGILAGAFIAFASEGSNMAAFNLFENH
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
ETYGLGKALAGSMFGIGLMLVIFAGGELFTGNTLIIISVLEKKVTLREMLRNWCTVYMGN
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEEEHHHHHHHHHHHHHHHHHHHHHH
LIGSLIIAFMMVESGLFNSGAHILGGQTIKIAAYKVGLSFMPALYLGIMANWLIGLAVWL
HHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
AHGAKSMVGKIFGIFCPIGLFVTSGFEQSIANMYYIPAGILAKSNINWVNASKLSPEELA
HHCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEEECCCCCEEECCCCEECCCCCCHHHHH
NLNWSNFIFNNLIPVTLGNIIGGAIFVGLIYWFVYLKPDTSQVMENTVVINNTLENEINL
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCEEEECCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formate [Cytoplasm]; formate [Periplasm] [C]

Specific reaction: formate [Cytoplasm] = formate [Periplasm] formate [Periplasm] = formate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]