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The map label for this gene is rnz [H]

Identifier: 28210613

GI number: 28210613

Start: 955787

End: 956671

Strand: Direct

Name: rnz [H]

Synonym: CTC00902

Alternate gene names: 28210613

Gene position: 955787-956671 (Clockwise)

Preceding gene: 28210612

Following gene: 28210614

Centisome position: 34.14

GC content: 32.77

Gene sequence:

>885_bases
ATGGATATGAATAATGAAACTAAATTAATATTACTTGGAACAGGTACACCTAATGCAGATCCAGATAGATCAGGTGCTTC
TGTTGCCGTAGTTGTAGGGGATAATTCTTATATTGTAGATTTTGGACCAGGAGTCGTAAGACAAGCTGCTAAAGCTTATA
AAAAAGGAGTGCATGCTCTTTTAGCTAAAAACCTAAAAACTGCTTTTTTAACACATTTACATTCAGATCATACAACAGGA
TATCCAGATCTTATATTTACTCCCTGGGTGCTAGAAAGAGAAGAACCATTAAAAGTTTTTGGGCCTAAGGGATTAAAATC
AATGACAGAACACATATTAGCTGCATATAAAATGGATATAGACGAAAGAGTTTATGGTTTAGAACCTGCTAATAAAAATG
GATGGAAAGTTGATGTAACAGAGATAGAATCAGGAGTTATATTTGAAGATGAAAAAGTAACAGTAGAAGCATTCCCTGTA
AAACATGGAGCTTTTGAAGCATATGCTTACAAATTCCATACACCAGATAAAACTATTGTTATATCTGGAGATACTGCACC
TGTAGATATTATGGTTGAAATAGCAAAAGGCTGTGATATACTTGTTCATGAGGTATATCATTTTGAAGGATTTAAATCAA
GAACAGAAGAATGGAGAAAATATCATAGTTCTGTTCACACATCTTCTTATGAATTAGGGGAAATAGCCCAAAAAGCTAAA
CCTAAACTAGTGGTTTTATACCATCAGCTTTACATGATGAATATGCAAAGTGAAGATGAAAATTTATCAAATGAAATAGC
CCTAAGAGATAAAGAGTTGGTAGAAGAAGTTAAGAGTAAGTTTTCAGGAAATGTAGTTTCTGGTAAGGATTTAGATATAT
TTTAA

Upstream 100 bases:

>100_bases
TAGCTAAAATAGATACAACGAATAAATTTTATGAACAAGAAAAAATATCAACAGAAGCTATGTAAATTTAATAAAAAGAT
AATTTGATATAATTGGAGGA

Downstream 100 bases:

>100_bases
CCTAATATAGTGTAAATATTAAGCTATATTTTTTAAAGAAGACTTTGAATTTTGGATTCAAGGTCTTCTTTAATGCTATC
TTTTGCACCAAAGTTCATGC

Product: putative hydrolase

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MDMNNETKLILLGTGTPNADPDRSGASVAVVVGDNSYIVDFGPGVVRQAAKAYKKGVHALLAKNLKTAFLTHLHSDHTTG
YPDLIFTPWVLEREEPLKVFGPKGLKSMTEHILAAYKMDIDERVYGLEPANKNGWKVDVTEIESGVIFEDEKVTVEAFPV
KHGAFEAYAYKFHTPDKTIVISGDTAPVDIMVEIAKGCDILVHEVYHFEGFKSRTEEWRKYHSSVHTSSYELGEIAQKAK
PKLVVLYHQLYMMNMQSEDENLSNEIALRDKELVEEVKSKFSGNVVSGKDLDIF

Sequences:

>Translated_294_residues
MDMNNETKLILLGTGTPNADPDRSGASVAVVVGDNSYIVDFGPGVVRQAAKAYKKGVHALLAKNLKTAFLTHLHSDHTTG
YPDLIFTPWVLEREEPLKVFGPKGLKSMTEHILAAYKMDIDERVYGLEPANKNGWKVDVTEIESGVIFEDEKVTVEAFPV
KHGAFEAYAYKFHTPDKTIVISGDTAPVDIMVEIAKGCDILVHEVYHFEGFKSRTEEWRKYHSSVHTSSYELGEIAQKAK
PKLVVLYHQLYMMNMQSEDENLSNEIALRDKELVEEVKSKFSGNVVSGKDLDIF
>Mature_294_residues
MDMNNETKLILLGTGTPNADPDRSGASVAVVVGDNSYIVDFGPGVVRQAAKAYKKGVHALLAKNLKTAFLTHLHSDHTTG
YPDLIFTPWVLEREEPLKVFGPKGLKSMTEHILAAYKMDIDERVYGLEPANKNGWKVDVTEIESGVIFEDEKVTVEAFPV
KHGAFEAYAYKFHTPDKTIVISGDTAPVDIMVEIAKGCDILVHEVYHFEGFKSRTEEWRKYHSSVHTSSYELGEIAQKAK
PKLVVLYHQLYMMNMQSEDENLSNEIALRDKELVEEVKSKFSGNVVSGKDLDIF

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR013471 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 32909; Mature: 32909

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMNNETKLILLGTGTPNADPDRSGASVAVVVGDNSYIVDFGPGVVRQAAKAYKKGVHAL
CCCCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHH
LAKNLKTAFLTHLHSDHTTGYPDLIFTPWVLEREEPLKVFGPKGLKSMTEHILAAYKMDI
HHHHHHHHHHHHHHCCCCCCCCCCEECCEEECCCCCCEEECCCHHHHHHHHHHHHHHCCH
DERVYGLEPANKNGWKVDVTEIESGVIFEDEKVTVEAFPVKHGAFEAYAYKFHTPDKTIV
HHHEECCCCCCCCCCEEEEEECCCCEEEECCEEEEEEEECCCCCEEEEEEEEECCCCEEE
ISGDTAPVDIMVEIAKGCDILVHEVYHFEGFKSRTEEWRKYHSSVHTSSYELGEIAQKAK
EECCCCCHHHEEEHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
PKLVVLYHQLYMMNMQSEDENLSNEIALRDKELVEEVKSKFSGNVVSGKDLDIF
CCEEEEEEHHHHHCCCCCCCCCCHHHEECCHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MDMNNETKLILLGTGTPNADPDRSGASVAVVVGDNSYIVDFGPGVVRQAAKAYKKGVHAL
CCCCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHH
LAKNLKTAFLTHLHSDHTTGYPDLIFTPWVLEREEPLKVFGPKGLKSMTEHILAAYKMDI
HHHHHHHHHHHHHHCCCCCCCCCCEECCEEECCCCCCEEECCCHHHHHHHHHHHHHHCCH
DERVYGLEPANKNGWKVDVTEIESGVIFEDEKVTVEAFPVKHGAFEAYAYKFHTPDKTIV
HHHEECCCCCCCCCCEEEEEECCCCEEEECCEEEEEEEECCCCCEEEEEEEEECCCCEEE
ISGDTAPVDIMVEIAKGCDILVHEVYHFEGFKSRTEEWRKYHSSVHTSSYELGEIAQKAK
EECCCCCHHHEEEHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
PKLVVLYHQLYMMNMQSEDENLSNEIALRDKELVEEVKSKFSGNVVSGKDLDIF
CCEEEEEEHHHHHCCCCCCCCCCHHHEECCHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]