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The map label for this gene is nhaC [H]

Identifier: 28210612

GI number: 28210612

Start: 954324

End: 955751

Strand: Direct

Name: nhaC [H]

Synonym: CTC00901

Alternate gene names: 28210612

Gene position: 954324-955751 (Clockwise)

Preceding gene: 28210611

Following gene: 28210613

Centisome position: 34.09

GC content: 29.41

Gene sequence:

>1428_bases
ATGAATAATCAAAAAAAATCAAATCTATTTTTAGCTTTATTACCTATAATATCTCTTATTCTTATGGCTTTAGCCTCAGC
AGTTAAATGGAAGTTTGGAATGAATGTTCCACTTATTTGTTCTATAATAGTAAGTTGCTTTGTAGGAAAGTACATTGGAA
TTTCTTGGAATGATATGGAAAAAGGACTTATGAGAGGTGCTTCTAGGGCAATGCCAGCAGTATTTATTTTAATAATAGTG
GGAACAATTATTGGATTATTTATAGCAAGTGGGATCATACCAACTTTGACTTATTATGGATTAACTATGATAACTCCAAG
ATTATTTATACCTTCAGCGGCATTAGTTACAGCTATAATAGCTACCGCTACAGGTACTTCCTTTAATTCCATCGCAACCA
TTGGTCTTGCTTTAATGGTAGTAGGAACTACTATGGGTTTTCCACCTCATATAGTTGCTGGTGCAGTTCTTTCAGGAGCT
TATTTTGGAGACAAGATATCTCCACTTTCAGATACTACAACTGTAGCATCATCAATGTCTGGATGCAATATATTTGAACA
TGTATTTCATATGATGATAAGTGCATTAATAGCATTATTTATTTCTATAGTAATTTACTATTTTATAGGTATAAATTTTA
TTTCAGGTGTTAATACAAATTGGAGTACAATAGAACAATTATCCAATGGACTAAGTGCTAATTTTAATATAAATCCAATT
TTAATATTAGTGCCTTTACTAAGTATAATTTTTGCACTTAAAAAAATTCCAACTATTCCATCTCTTTTAGCAACATCTAT
TATTAGTGGTATATTTGCAATGATATTTCAAGGTGTTCATATTACTAAATTATTTAAAATTGCAACTTTTGGATATGAAA
GTAATACGGGAATAAAGATGTTGGATAGTCTTTTATCAAGGGGAGGAATTAATTCTATGGGAGGAACTATAATATTAATA
ATTATGGCTTCTGCTTTAGGGGGAATATTAGAGGAAATAGGTTCTTTAAAAACAATTTTAAATACTATAAAAAAAGTAGT
ACATTCTGACAGAGGTATAATAATATCTTCCATGTTTAGTGGATTATTTATAAGTTTTGCAACAGGTGCACAAATTTTAG
CTATAATGATACCTGCAAGAATGTTTTCAAAAGTATTTGAAGAAAGAGGACTTGAAGTTAAGAATTTATCTAGAGTAGCT
GAAACAGTAGGAACCGTAGGTATAATACTAGTGCCATGGAGTGTTCATGCTATATTCGCTTCTAATATTCTAGGAGTAGA
ACCTTTTAAATTTATACCTTTTGTATTTTTTGCTTTTATAGATATTTTTATAAATATAGTTATGGCTTACACTGGAATTG
GAATAGCTAAAATAGATACAACGAATAAATTTTATGAACAAGAAAAAATATCAACAGAAGCTATGTAA

Upstream 100 bases:

>100_bases
TTAATTAGTTTTAATAAATTCATTTTAACACTCAAGTCTATCATTCATAAAACTCATTCTACAAAAACCTACTAATTGAA
AAATATAGGGGGATGATTTT

Downstream 100 bases:

>100_bases
ATTTAATAAAAAGATAATTTGATATAATTGGAGGAATGGATATGAATAATGAAACTAAATTAATATTACTTGGAACAGGT
ACACCTAATGCAGATCCAGA

Product: Na+/H+ antiporter nhaC

Products: NA

Alternate protein names: Sodium/hydrogen antiporter; Sodium/proton antiporter [H]

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MNNQKKSNLFLALLPIISLILMALASAVKWKFGMNVPLICSIIVSCFVGKYIGISWNDMEKGLMRGASRAMPAVFILIIV
GTIIGLFIASGIIPTLTYYGLTMITPRLFIPSAALVTAIIATATGTSFNSIATIGLALMVVGTTMGFPPHIVAGAVLSGA
YFGDKISPLSDTTTVASSMSGCNIFEHVFHMMISALIALFISIVIYYFIGINFISGVNTNWSTIEQLSNGLSANFNINPI
LILVPLLSIIFALKKIPTIPSLLATSIISGIFAMIFQGVHITKLFKIATFGYESNTGIKMLDSLLSRGGINSMGGTIILI
IMASALGGILEEIGSLKTILNTIKKVVHSDRGIIISSMFSGLFISFATGAQILAIMIPARMFSKVFEERGLEVKNLSRVA
ETVGTVGIILVPWSVHAIFASNILGVEPFKFIPFVFFAFIDIFINIVMAYTGIGIAKIDTTNKFYEQEKISTEAM

Sequences:

>Translated_475_residues
MNNQKKSNLFLALLPIISLILMALASAVKWKFGMNVPLICSIIVSCFVGKYIGISWNDMEKGLMRGASRAMPAVFILIIV
GTIIGLFIASGIIPTLTYYGLTMITPRLFIPSAALVTAIIATATGTSFNSIATIGLALMVVGTTMGFPPHIVAGAVLSGA
YFGDKISPLSDTTTVASSMSGCNIFEHVFHMMISALIALFISIVIYYFIGINFISGVNTNWSTIEQLSNGLSANFNINPI
LILVPLLSIIFALKKIPTIPSLLATSIISGIFAMIFQGVHITKLFKIATFGYESNTGIKMLDSLLSRGGINSMGGTIILI
IMASALGGILEEIGSLKTILNTIKKVVHSDRGIIISSMFSGLFISFATGAQILAIMIPARMFSKVFEERGLEVKNLSRVA
ETVGTVGIILVPWSVHAIFASNILGVEPFKFIPFVFFAFIDIFINIVMAYTGIGIAKIDTTNKFYEQEKISTEAM
>Mature_475_residues
MNNQKKSNLFLALLPIISLILMALASAVKWKFGMNVPLICSIIVSCFVGKYIGISWNDMEKGLMRGASRAMPAVFILIIV
GTIIGLFIASGIIPTLTYYGLTMITPRLFIPSAALVTAIIATATGTSFNSIATIGLALMVVGTTMGFPPHIVAGAVLSGA
YFGDKISPLSDTTTVASSMSGCNIFEHVFHMMISALIALFISIVIYYFIGINFISGVNTNWSTIEQLSNGLSANFNINPI
LILVPLLSIIFALKKIPTIPSLLATSIISGIFAMIFQGVHITKLFKIATFGYESNTGIKMLDSLLSRGGINSMGGTIILI
IMASALGGILEEIGSLKTILNTIKKVVHSDRGIIISSMFSGLFISFATGAQILAIMIPARMFSKVFEERGLEVKNLSRVA
ETVGTVGIILVPWSVHAIFASNILGVEPFKFIPFVFFAFIDIFINIVMAYTGIGIAKIDTTNKFYEQEKISTEAM

Specific function: Na(+)/H(+) antiporter. Involved in pH homeostasis and sodium extrusion [H]

COG id: COG1757

COG function: function code C; Na+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nhaC Na(+)/H(+) antiporter family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004770
- InterPro:   IPR018461 [H]

Pfam domain/function: PF03553 Na_H_antiporter [H]

EC number: NA

Molecular weight: Translated: 51080; Mature: 51080

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNQKKSNLFLALLPIISLILMALASAVKWKFGMNVPLICSIIVSCFVGKYIGISWNDME
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
KGLMRGASRAMPAVFILIIVGTIIGLFIASGIIPTLTYYGLTMITPRLFIPSAALVTAII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHH
ATATGTSFNSIATIGLALMVVGTTMGFPPHIVAGAVLSGAYFGDKISPLSDTTTVASSMS
HHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
GCNIFEHVFHMMISALIALFISIVIYYFIGINFISGVNTNWSTIEQLSNGLSANFNINPI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCHH
LILVPLLSIIFALKKIPTIPSLLATSIISGIFAMIFQGVHITKLFKIATFGYESNTGIKM
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHH
LDSLLSRGGINSMGGTIILIIMASALGGILEEIGSLKTILNTIKKVVHSDRGIIISSMFS
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
GLFISFATGAQILAIMIPARMFSKVFEERGLEVKNLSRVAETVGTVGIILVPWSVHAIFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECHHHHHHHH
SNILGVEPFKFIPFVFFAFIDIFINIVMAYTGIGIAKIDTTNKFYEQEKISTEAM
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MNNQKKSNLFLALLPIISLILMALASAVKWKFGMNVPLICSIIVSCFVGKYIGISWNDME
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
KGLMRGASRAMPAVFILIIVGTIIGLFIASGIIPTLTYYGLTMITPRLFIPSAALVTAII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHH
ATATGTSFNSIATIGLALMVVGTTMGFPPHIVAGAVLSGAYFGDKISPLSDTTTVASSMS
HHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
GCNIFEHVFHMMISALIALFISIVIYYFIGINFISGVNTNWSTIEQLSNGLSANFNINPI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCHH
LILVPLLSIIFALKKIPTIPSLLATSIISGIFAMIFQGVHITKLFKIATFGYESNTGIKM
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHH
LDSLLSRGGINSMGGTIILIIMASALGGILEEIGSLKTILNTIKKVVHSDRGIIISSMFS
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
GLFISFATGAQILAIMIPARMFSKVFEERGLEVKNLSRVAETVGTVGIILVPWSVHAIFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECHHHHHHHH
SNILGVEPFKFIPFVFFAFIDIFINIVMAYTGIGIAKIDTTNKFYEQEKISTEAM
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1660475; 9190799 [H]