Click here to switch to the map view.

The map label for this gene is ahpC [C]

Identifier: 28210605

GI number: 28210605

Start: 947821

End: 948492

Strand: Direct

Name: ahpC [C]

Synonym: CTC00894

Alternate gene names: 28210605

Gene position: 947821-948492 (Clockwise)

Preceding gene: 28210604

Following gene: 28210606

Centisome position: 33.86

GC content: 31.55

Gene sequence:

>672_bases
ATGAAAGATTGTAAAGAGGAGAAGCATAAGTGCTTAAATATAGGAATGAAAGCACCAGACTTTTGTGCAACAACAACTTT
TGGAAGTATTAGACTTTCTGATTTTAGGGGGAAGTGGGTTATATTATTTTCTCATCCTGGTGACTTTACACCTGTTTGTA
CAACTGAATTTATTGGATTTGCGCAATGTTATCCATATTTTAAAAAAAGAAATGTACAGCTTTTAGGATTGAGTATAGAT
AGTAATCCATCCCATTTAGCTTGGGTATATAACATATATATAAATACAGGAATACAAATTCCATTTCCTATAATAGCTGA
TAGGGATGGCTCTATTTCAAGAATGTATGGAATGGTTTCACCTTATATAAGTTCTACTGAAACAGTAAGAAGCGTTTTTA
TAATAGATGAAGATGGTATAATTAGAACAATATTAACTTATCCCCTTACAAATGGTAGGAATATAGGGGAGATTTTAAGA
ATGGTATGTGCACTTCAAACTACAGATGAAGAAAAAGTAGTAACACCAGCTAATTGGATACCAGGACGTCCTGTTATGGT
ACCACCTCCTAAAACATATAATGAATTAATAAATAGGAGAAAAGATAATCCAGAACTTTGCTGTATAGATTGGTATTGGT
GTTATAAAAAACAAAATAAAAATTTTGCGTAA

Upstream 100 bases:

>100_bases
CTTACATTTTTTTTAGATTAAAATTTTACATGCACCATAAATATATTGATTGTGTATCATAGTAATGTAGTAATAAATAT
CTATATTGGTGGTGTAATTT

Downstream 100 bases:

>100_bases
CAAAATTTTTATTAATGAACAATGATTAATGAACAATTGTGGATATTTTTTCTCCATTAACATTACGAAAAAATTTTAAT
TGTAAATTTATACATTAAGT

Product: peroxiredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MKDCKEEKHKCLNIGMKAPDFCATTTFGSIRLSDFRGKWVILFSHPGDFTPVCTTEFIGFAQCYPYFKKRNVQLLGLSID
SNPSHLAWVYNIYINTGIQIPFPIIADRDGSISRMYGMVSPYISSTETVRSVFIIDEDGIIRTILTYPLTNGRNIGEILR
MVCALQTTDEEKVVTPANWIPGRPVMVPPPKTYNELINRRKDNPELCCIDWYWCYKKQNKNFA

Sequences:

>Translated_223_residues
MKDCKEEKHKCLNIGMKAPDFCATTTFGSIRLSDFRGKWVILFSHPGDFTPVCTTEFIGFAQCYPYFKKRNVQLLGLSID
SNPSHLAWVYNIYINTGIQIPFPIIADRDGSISRMYGMVSPYISSTETVRSVFIIDEDGIIRTILTYPLTNGRNIGEILR
MVCALQTTDEEKVVTPANWIPGRPVMVPPPKTYNELINRRKDNPELCCIDWYWCYKKQNKNFA
>Mature_223_residues
MKDCKEEKHKCLNIGMKAPDFCATTTFGSIRLSDFRGKWVILFSHPGDFTPVCTTEFIGFAQCYPYFKKRNVQLLGLSID
SNPSHLAWVYNIYINTGIQIPFPIIADRDGSISRMYGMVSPYISSTETVRSVFIIDEDGIIRTILTYPLTNGRNIGEILR
MVCALQTTDEEKVVTPANWIPGRPVMVPPPKTYNELINRRKDNPELCCIDWYWCYKKQNKNFA

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=187, Percent_Identity=46.524064171123, Blast_Score=154, Evalue=5e-38,
Organism=Homo sapiens, GI4505591, Length=195, Percent_Identity=38.4615384615385, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI32455266, Length=195, Percent_Identity=38.4615384615385, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI32455264, Length=195, Percent_Identity=38.4615384615385, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI32189392, Length=180, Percent_Identity=40, Blast_Score=126, Evalue=1e-29,
Organism=Homo sapiens, GI5453549, Length=166, Percent_Identity=39.1566265060241, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI32483377, Length=188, Percent_Identity=35.1063829787234, Blast_Score=116, Evalue=1e-26,
Organism=Homo sapiens, GI5802974, Length=191, Percent_Identity=34.5549738219895, Blast_Score=116, Evalue=1e-26,
Organism=Homo sapiens, GI33188454, Length=79, Percent_Identity=48.1012658227848, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1786822, Length=163, Percent_Identity=29.4478527607362, Blast_Score=78, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI25153706, Length=214, Percent_Identity=38.3177570093458, Blast_Score=137, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI193204376, Length=192, Percent_Identity=36.4583333333333, Blast_Score=113, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI32565831, Length=192, Percent_Identity=36.4583333333333, Blast_Score=113, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17554494, Length=174, Percent_Identity=32.7586206896552, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319407, Length=202, Percent_Identity=45.5445544554455, Blast_Score=168, Evalue=8e-43,
Organism=Saccharomyces cerevisiae, GI6323613, Length=195, Percent_Identity=36.4102564102564, Blast_Score=108, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6320661, Length=184, Percent_Identity=36.4130434782609, Blast_Score=108, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24652436, Length=193, Percent_Identity=42.4870466321244, Blast_Score=146, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24652434, Length=193, Percent_Identity=42.4870466321244, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI17975518, Length=193, Percent_Identity=42.4870466321244, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24581278, Length=186, Percent_Identity=40.8602150537634, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI17157991, Length=183, Percent_Identity=38.2513661202186, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24641739, Length=183, Percent_Identity=38.2513661202186, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24656348, Length=184, Percent_Identity=37.5, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17864676, Length=184, Percent_Identity=37.5, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17738015, Length=185, Percent_Identity=34.5945945945946, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI21357347, Length=182, Percent_Identity=35.1648351648352, Blast_Score=115, Evalue=3e-26,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 25582; Mature: 25582

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDCKEEKHKCLNIGMKAPDFCATTTFGSIRLSDFRGKWVILFSHPGDFTPVCTTEFIGF
CCCHHHHHHHHHHCCCCCCCCEEECCCCCEEEECCCCCEEEEECCCCCCCCCHHHHHHHH
AQCYPYFKKRNVQLLGLSIDSNPSHLAWVYNIYINTGIQIPFPIIADRDGSISRMYGMVS
HHHHHHHHCCCEEEEEEEECCCCCEEEEEEEEEEECCCCCCCEEEECCCCCHHHHHHHHC
PYISSTETVRSVFIIDEDGIIRTILTYPLTNGRNIGEILRMVCALQTTDEEKVVTPANWI
CCCCCCCCEEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCEECCCCCC
PGRPVMVPPPKTYNELINRRKDNPELCCIDWYWCYKKQNKNFA
CCCCEEECCCHHHHHHHHCCCCCCCEEEEEEEEEEEECCCCCC
>Mature Secondary Structure
MKDCKEEKHKCLNIGMKAPDFCATTTFGSIRLSDFRGKWVILFSHPGDFTPVCTTEFIGF
CCCHHHHHHHHHHCCCCCCCCEEECCCCCEEEECCCCCEEEEECCCCCCCCCHHHHHHHH
AQCYPYFKKRNVQLLGLSIDSNPSHLAWVYNIYINTGIQIPFPIIADRDGSISRMYGMVS
HHHHHHHHCCCEEEEEEEECCCCCEEEEEEEEEEECCCCCCCEEEECCCCCHHHHHHHHC
PYISSTETVRSVFIIDEDGIIRTILTYPLTNGRNIGEILRMVCALQTTDEEKVVTPANWI
CCCCCCCCEEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCEECCCCCC
PGRPVMVPPPKTYNELINRRKDNPELCCIDWYWCYKKQNKNFA
CCCCEEECCCHHHHHHHHCCCCCCCEEEEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]