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The map label for this gene is sbcD [H]

Identifier: 28210314

GI number: 28210314

Start: 599240

End: 600415

Strand: Direct

Name: sbcD [H]

Synonym: CTC00578

Alternate gene names: 28210314

Gene position: 599240-600415 (Clockwise)

Preceding gene: 28210313

Following gene: 28210315

Centisome position: 21.41

GC content: 28.32

Gene sequence:

>1176_bases
ATGAAAATAATTCATACTGGAGATTGGCATATAGGAAAAATAGTAAATGAATTTAGTATGATAGAGGATCAAAAAATCGT
ATTAGAACAATTAATAAATATAATTAAAGAAGAAAAGCCTAATGCATTAATTATAGCTGGAGACTTATATGATAGAAGTA
TACCACCTGTGGAAGCTGTAGAATTATTAGATAGGACTTTTAATAAAATTCTGTTAGATTTAAAAGTTCCCATATTAGCT
ATAGCTGGAAATCATGATAGTCCAGAAAGACTAGCTTTTGGCAGTAGAATTCTTACGGAAAATGGTCTTCATATAGCGGG
AAGTTTTAATAAAGAAAAAAGAGAGATAAAAAAAGTAATATTAAAAAGTAATAATGAAAATTTTAATTTTTATTTGCTAC
CTTACTGTGATCCAAAAGAAATAAAACATATTTTTCAAGATGATAAAATTTCTACTCATGATGACGCAATGAGGGTTTTA
GTAGACATCATAGAAAAGGATTTAAATAAAAATGAAAAAAATGTATTAATAACTCACGCATATACAAGCTTTATAAAAGA
CAACCAAAGTCTTGAAGTTTGCCAATCGGAAAGACCTCTAAGTATAGGGGGGACAGATATTGTAAATGCAGAGTATTTTT
CCGAATTTACATATACAGCTCTTGGACATTTACACAAGCCTCAAAAGGTTAAAGATAATAAAATAAGATATTCAGGATCT
CTTTTAAAATATTCTTTTTCAGAAGTAAACCATAAAAAAGGAGCAACTATAGTTAATATAAATAAATATGGAGAAATCCA
AATAGATTTTAAAGAATTTAAACCTAAAAGAGATATGAGAATCATAAAAGGACCATTAGAAAAACTGATAAGTCCAGAGA
TTTATAAGGGTACTAATATAGAAGATTACGTATATGCATTATTAACAGATGAAGGGGAACTAGTAGATCCCATAGCAAAA
TTAAGAGCTGTTTACCCTAATATAATGGGACTTAGCAGAGAAGGGGAAATAAAAAAAGAAGATAGTAAAACATCAGCAGG
GCAGGGATACAAAAACAAAACTAAATTACAGCTTTTTAAAGAGTTTTATAATTCGATAACAGGAAAAGACTTGGAAAAAG
AAAGTCTACAAATAATAACCAATGTAATAGAGAAAATAGAAAAAGAGGTGAACTAG

Upstream 100 bases:

>100_bases
GTTAAATATTTAAACTCTGTCCCTATATATTATTGTTTTTACCTTTTGATAATAGTATATTAAAATATAGTTATATTAAA
CATCTTTTGGAGGTGTAAAT

Downstream 100 bases:

>100_bases
ATGAAGCCTTTAAAGTTAACTATGTGTGCATTTGGACCCTATGCAGATGTGCAAATTATAGATTTTACGGAGCTAGATAA
TAGAAATATATTTCTTATAA

Product: exonuclease sbcD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MKIIHTGDWHIGKIVNEFSMIEDQKIVLEQLINIIKEEKPNALIIAGDLYDRSIPPVEAVELLDRTFNKILLDLKVPILA
IAGNHDSPERLAFGSRILTENGLHIAGSFNKEKREIKKVILKSNNENFNFYLLPYCDPKEIKHIFQDDKISTHDDAMRVL
VDIIEKDLNKNEKNVLITHAYTSFIKDNQSLEVCQSERPLSIGGTDIVNAEYFSEFTYTALGHLHKPQKVKDNKIRYSGS
LLKYSFSEVNHKKGATIVNINKYGEIQIDFKEFKPKRDMRIIKGPLEKLISPEIYKGTNIEDYVYALLTDEGELVDPIAK
LRAVYPNIMGLSREGEIKKEDSKTSAGQGYKNKTKLQLFKEFYNSITGKDLEKESLQIITNVIEKIEKEVN

Sequences:

>Translated_391_residues
MKIIHTGDWHIGKIVNEFSMIEDQKIVLEQLINIIKEEKPNALIIAGDLYDRSIPPVEAVELLDRTFNKILLDLKVPILA
IAGNHDSPERLAFGSRILTENGLHIAGSFNKEKREIKKVILKSNNENFNFYLLPYCDPKEIKHIFQDDKISTHDDAMRVL
VDIIEKDLNKNEKNVLITHAYTSFIKDNQSLEVCQSERPLSIGGTDIVNAEYFSEFTYTALGHLHKPQKVKDNKIRYSGS
LLKYSFSEVNHKKGATIVNINKYGEIQIDFKEFKPKRDMRIIKGPLEKLISPEIYKGTNIEDYVYALLTDEGELVDPIAK
LRAVYPNIMGLSREGEIKKEDSKTSAGQGYKNKTKLQLFKEFYNSITGKDLEKESLQIITNVIEKIEKEVN
>Mature_391_residues
MKIIHTGDWHIGKIVNEFSMIEDQKIVLEQLINIIKEEKPNALIIAGDLYDRSIPPVEAVELLDRTFNKILLDLKVPILA
IAGNHDSPERLAFGSRILTENGLHIAGSFNKEKREIKKVILKSNNENFNFYLLPYCDPKEIKHIFQDDKISTHDDAMRVL
VDIIEKDLNKNEKNVLITHAYTSFIKDNQSLEVCQSERPLSIGGTDIVNAEYFSEFTYTALGHLHKPQKVKDNKIRYSGS
LLKYSFSEVNHKKGATIVNINKYGEIQIDFKEFKPKRDMRIIKGPLEKLISPEIYKGTNIEDYVYALLTDEGELVDPIAK
LRAVYPNIMGLSREGEIKKEDSKTSAGQGYKNKTKLQLFKEFYNSITGKDLEKESLQIITNVIEKIEKEVN

Specific function: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand

COG id: COG0420

COG function: function code L; DNA repair exonuclease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sbcD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR004593 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: 3.1.11.-

Molecular weight: Translated: 44785; Mature: 44785

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIHTGDWHIGKIVNEFSMIEDQKIVLEQLINIIKEEKPNALIIAGDLYDRSIPPVEAV
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHH
ELLDRTFNKILLDLKVPILAIAGNHDSPERLAFGSRILTENGLHIAGSFNKEKREIKKVI
HHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCHHEECCCEEEEECCCHHHHHHHHHH
LKSNNENFNFYLLPYCDPKEIKHIFQDDKISTHDDAMRVLVDIIEKDLNKNEKNVLITHA
HHCCCCCEEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEH
YTSFIKDNQSLEVCQSERPLSIGGTDIVNAEYFSEFTYTALGHLHKPQKVKDNKIRYSGS
HHHHHCCCCCHHHHHCCCCCCCCCCCEECHHHHHHHHHHHHHHCCCCCCCCCCEEEECCC
LLKYSFSEVNHKKGATIVNINKYGEIQIDFKEFKPKRDMRIIKGPLEKLISPEIYKGTNI
HHEEHHHHHCCCCCCEEEEECCCCEEEEEHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCH
EDYVYALLTDEGELVDPIAKLRAVYPNIMGLSREGEIKKEDSKTSAGQGYKNKTKLQLFK
HHEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
EFYNSITGKDLEKESLQIITNVIEKIEKEVN
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKIIHTGDWHIGKIVNEFSMIEDQKIVLEQLINIIKEEKPNALIIAGDLYDRSIPPVEAV
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHH
ELLDRTFNKILLDLKVPILAIAGNHDSPERLAFGSRILTENGLHIAGSFNKEKREIKKVI
HHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCHHEECCCEEEEECCCHHHHHHHHHH
LKSNNENFNFYLLPYCDPKEIKHIFQDDKISTHDDAMRVLVDIIEKDLNKNEKNVLITHA
HHCCCCCEEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEH
YTSFIKDNQSLEVCQSERPLSIGGTDIVNAEYFSEFTYTALGHLHKPQKVKDNKIRYSGS
HHHHHCCCCCHHHHHCCCCCCCCCCCEECHHHHHHHHHHHHHHCCCCCCCCCCEEEECCC
LLKYSFSEVNHKKGATIVNINKYGEIQIDFKEFKPKRDMRIIKGPLEKLISPEIYKGTNI
HHEEHHHHHCCCCCCEEEEECCCCEEEEEHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCH
EDYVYALLTDEGELVDPIAKLRAVYPNIMGLSREGEIKKEDSKTSAGQGYKNKTKLQLFK
HHEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
EFYNSITGKDLEKESLQIITNVIEKIEKEVN
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA