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The map label for this gene is pfpI [H]

Identifier: 28210309

GI number: 28210309

Start: 592346

End: 592876

Strand: Direct

Name: pfpI [H]

Synonym: CTC00573

Alternate gene names: 28210309

Gene position: 592346-592876 (Clockwise)

Preceding gene: 28210308

Following gene: 28210311

Centisome position: 21.16

GC content: 31.26

Gene sequence:

>531_bases
ATGACTAAATTGAAACTTACAGGGAAAAGAATGATAATGTTAGCAGAAGAAGGATTTGACGATTTAGAACTTTGGTATCC
AGTAATAAGACTGAGAGAAGAGGGTTGTGAAGTAGTTATTGTAGGATCTGGTACTAGTAAAATTTATAAAGGAAAACATG
GAATACCTGTAGATGTTGATAAAAATGCTGATGAGGTATCTTCAAAAGAGTTTGATGGAATAATAGTTCCAGGTGGATGG
GCACCAGATAAATTAAGAAGATATAACAGCGTAAAAAAATTAGTAGGAGACTTCGCAAAAGAAAATAAATTATTAGCTAC
AATATGTCATGGAGGATGGGTATTTATATCAGCAGGAGTTATAAAAGATTATAAAATGACTTGTGTAAATGCAATAATAG
ATGATGTGAAAAATGCTGGAGCCAATTATATAGATAGTGAAGTAGCGGTAGACAGAAATTTAATAACATCTAGAAGTCCT
AAGGATTTACCTGCATATATGAGAGCTATTATAGATTATTTAGATAAATAA

Upstream 100 bases:

>100_bases
TATCAAAAGCATATAAAAATGTTTGTAAACTTAGAAGCTATTTGATGGTATAATAAATACAAGATTTCGTGATCTAATAT
ACAATATATATAAAGGGGAG

Downstream 100 bases:

>100_bases
AATTTATGAGATTAAAGTATTATAAATTTATTTTAGTACTTTAATCTCTTTTTATTTTTGCAACTAATTATTAGTTAATA
TATACTTTTATTTCGGCAGT

Product: protease I

Products: NA

Alternate protein names: Intracellular protease I [H]

Number of amino acids: Translated: 176; Mature: 175

Protein sequence:

>176_residues
MTKLKLTGKRMIMLAEEGFDDLELWYPVIRLREEGCEVVIVGSGTSKIYKGKHGIPVDVDKNADEVSSKEFDGIIVPGGW
APDKLRRYNSVKKLVGDFAKENKLLATICHGGWVFISAGVIKDYKMTCVNAIIDDVKNAGANYIDSEVAVDRNLITSRSP
KDLPAYMRAIIDYLDK

Sequences:

>Translated_176_residues
MTKLKLTGKRMIMLAEEGFDDLELWYPVIRLREEGCEVVIVGSGTSKIYKGKHGIPVDVDKNADEVSSKEFDGIIVPGGW
APDKLRRYNSVKKLVGDFAKENKLLATICHGGWVFISAGVIKDYKMTCVNAIIDDVKNAGANYIDSEVAVDRNLITSRSP
KDLPAYMRAIIDYLDK
>Mature_175_residues
TKLKLTGKRMIMLAEEGFDDLELWYPVIRLREEGCEVVIVGSGTSKIYKGKHGIPVDVDKNADEVSSKEFDGIIVPGGWA
PDKLRRYNSVKKLVGDFAKENKLLATICHGGWVFISAGVIKDYKMTCVNAIIDDVKNAGANYIDSEVAVDRNLITSRSPK
DLPAYMRAIIDYLDK

Specific function: Unknown

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PfpI endopeptidase domain [H]

Homologues:

Organism=Escherichia coli, GI87082219, Length=168, Percent_Identity=42.8571428571429, Blast_Score=133, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI17558714, Length=167, Percent_Identity=28.1437125748503, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006286
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: 3.2.-.-

Molecular weight: Translated: 19585; Mature: 19454

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLKLTGKRMIMLAEEGFDDLELWYPVIRLREEGCEVVIVGSGTSKIYKGKHGIPVDVD
CCCEEECCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCEECCCCCCCCCCC
KNADEVSSKEFDGIIVPGGWAPDKLRRYNSVKKLVGDFAKENKLLATICHGGWVFISAGV
CCCHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEECCH
IKDYKMTCVNAIIDDVKNAGANYIDSEVAVDRNLITSRSPKDLPAYMRAIIDYLDK
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKLKLTGKRMIMLAEEGFDDLELWYPVIRLREEGCEVVIVGSGTSKIYKGKHGIPVDVD
CCEEECCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCEECCCCCCCCCCC
KNADEVSSKEFDGIIVPGGWAPDKLRRYNSVKKLVGDFAKENKLLATICHGGWVFISAGV
CCCHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEECCH
IKDYKMTCVNAIIDDVKNAGANYIDSEVAVDRNLITSRSPKDLPAYMRAIIDYLDK
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA