Click here to switch to the map view.

The map label for this gene is macB [H]

Identifier: 28210234

GI number: 28210234

Start: 491488

End: 492702

Strand: Direct

Name: macB [H]

Synonym: CTC00486

Alternate gene names: 28210234

Gene position: 491488-492702 (Clockwise)

Preceding gene: 28210233

Following gene: 28210235

Centisome position: 17.56

GC content: 30.86

Gene sequence:

>1215_bases
ATGAATATATTAGAAGGTTTTCAATCTGCCCTACAGAGTGTAAAATCTAATAAACTGAGATCTTTTTTAACTATGTTGGG
TATAATCATTGGTATATCTTCTGTAATAACTATAGTATCCATAGGAGATGGGGCCAAACAATTTATAACAGGAGAATTTG
AAAATATAGGGACTAATCTTATAAATATGAAGATGAGTTCTTCTCCAGACATTACCATAGAAAAAAGAGATTATTTTACC
ATGGATGATGTTAAGCTTTTAAAAAATAAAATATCAGAAATTGAATATGCATCACCTGAATTGGGGTTATTTGGTAAAGC
TAAAGTAGAAAATAAAATGAAACAAGCAAGCATAATGGCAACAAATGAGGATTCTAAAAAGTTTTATAATTTAAAGATGA
TGCATGGAAGATATTTAAATGAACATGATTTAGACTCAAGAAGGGCTGTTGCAACAATAGATGATAGAACAGCTAAACAC
CTTTTTAACAGAGTAGATGTAGTGGGAGAAAAAATAAAATTTAATATTGGAGATAAAAATATAGATTTAAGTATAATAGG
TGTTTTTAAAGATCCTAGAGGAAATATGGGAGATGCTTTTGGTGGTAGTAATATGCCAGGATTTTTAACAATGCCATTAA
CTATAGTAGATAGGCTAACAGAAGATACTGATATACGTGGGGTTTCTGTTATGTTGTCTGATATGAAGAATGCAGATCAA
GTATCCAATAAAATGATAAGACTTATTGAAAATAAACATAAAAATAGGAATAAGTATACAGCGGAAAAAGGATTTAAAGA
ATTAGAAAGTATTAATAAGGTGTTAGGGGTAATAACTATGGTCCTAGGGGCTATAGCTGCAATTTCTCTTTTAGTTGGAG
GAATAGGAGTTATGAATATAATGCTTGTCTCTGTTACAGAGAGAACTAGAGAGATAGGTATAAGAAAAGCAATAGGAGCT
AAGACTCGGGATATAAGGATTCAATTTCTAATGGAATCTATAATACTTTGTCTAATCGGAGGAAGCGTAGGAACTATACT
TGGTATATTAGTGGGAAAATTTGCAGGAAGTCTTATAAATATTCAGATTGTAGTATCATTGAAAGTTATATTAACAGCCT
TTGGATTTTCTTCAGCAGTTGGAATATTCTTTGGACTTTATCCAGCAAATCAAGCTGCACAATTAAATCCAATTGATGCA
CTAAGGTACGAATAA

Upstream 100 bases:

>100_bases
CAATGCATACTAAAAGAGCAGTAGTTTTTAAGGATGGAAACATAATTTCAGATAAATTAATAAATGAAAGTGAAAGAATT
ATAGTTGGGGGGCAGAAAGT

Downstream 100 bases:

>100_bases
AAGAGAGGATGAGAATATATGAAAAAAATTAAAAAAGTTATATTATGCCTCTTAGTTATTAATACAATATGTATTTTCCC
TAAATCACAGGGAACTATAG

Product: ABC transporter permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MNILEGFQSALQSVKSNKLRSFLTMLGIIIGISSVITIVSIGDGAKQFITGEFENIGTNLINMKMSSSPDITIEKRDYFT
MDDVKLLKNKISEIEYASPELGLFGKAKVENKMKQASIMATNEDSKKFYNLKMMHGRYLNEHDLDSRRAVATIDDRTAKH
LFNRVDVVGEKIKFNIGDKNIDLSIIGVFKDPRGNMGDAFGGSNMPGFLTMPLTIVDRLTEDTDIRGVSVMLSDMKNADQ
VSNKMIRLIENKHKNRNKYTAEKGFKELESINKVLGVITMVLGAIAAISLLVGGIGVMNIMLVSVTERTREIGIRKAIGA
KTRDIRIQFLMESIILCLIGGSVGTILGILVGKFAGSLINIQIVVSLKVILTAFGFSSAVGIFFGLYPANQAAQLNPIDA
LRYE

Sequences:

>Translated_404_residues
MNILEGFQSALQSVKSNKLRSFLTMLGIIIGISSVITIVSIGDGAKQFITGEFENIGTNLINMKMSSSPDITIEKRDYFT
MDDVKLLKNKISEIEYASPELGLFGKAKVENKMKQASIMATNEDSKKFYNLKMMHGRYLNEHDLDSRRAVATIDDRTAKH
LFNRVDVVGEKIKFNIGDKNIDLSIIGVFKDPRGNMGDAFGGSNMPGFLTMPLTIVDRLTEDTDIRGVSVMLSDMKNADQ
VSNKMIRLIENKHKNRNKYTAEKGFKELESINKVLGVITMVLGAIAAISLLVGGIGVMNIMLVSVTERTREIGIRKAIGA
KTRDIRIQFLMESIILCLIGGSVGTILGILVGKFAGSLINIQIVVSLKVILTAFGFSSAVGIFFGLYPANQAAQLNPIDA
LRYE
>Mature_404_residues
MNILEGFQSALQSVKSNKLRSFLTMLGIIIGISSVITIVSIGDGAKQFITGEFENIGTNLINMKMSSSPDITIEKRDYFT
MDDVKLLKNKISEIEYASPELGLFGKAKVENKMKQASIMATNEDSKKFYNLKMMHGRYLNEHDLDSRRAVATIDDRTAKH
LFNRVDVVGEKIKFNIGDKNIDLSIIGVFKDPRGNMGDAFGGSNMPGFLTMPLTIVDRLTEDTDIRGVSVMLSDMKNADQ
VSNKMIRLIENKHKNRNKYTAEKGFKELESINKVLGVITMVLGAIAAISLLVGGIGVMNIMLVSVTERTREIGIRKAIGA
KTRDIRIQFLMESIILCLIGGSVGTILGILVGKFAGSLINIQIVVSLKVILTAFGFSSAVGIFFGLYPANQAAQLNPIDA
LRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=403, Percent_Identity=33.7468982630273, Blast_Score=194, Evalue=7e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44417; Mature: 44417

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILEGFQSALQSVKSNKLRSFLTMLGIIIGISSVITIVSIGDGAKQFITGEFENIGTNL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHCCCHHHCCCCE
INMKMSSSPDITIEKRDYFTMDDVKLLKNKISEIEYASPELGLFGKAKVENKMKQASIMA
EEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHEEE
TNEDSKKFYNLKMMHGRYLNEHDLDSRRAVATIDDRTAKHLFNRVDVVGEKIKFNIGDKN
ECCCCHHHEEEEEECCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHCCCEEEEEECCCC
IDLSIIGVFKDPRGNMGDAFGGSNMPGFLTMPLTIVDRLTEDTDIRGVSVMLSDMKNADQ
EEEEEEEEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHCCCHHH
VSNKMIRLIENKHKNRNKYTAEKGFKELESINKVLGVITMVLGAIAAISLLVGGIGVMNI
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLVSVTERTREIGIRKAIGAKTRDIRIQFLMESIILCLIGGSVGTILGILVGKFAGSLIN
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEE
IQIVVSLKVILTAFGFSSAVGIFFGLYPANQAAQLNPIDALRYE
EEEEHHHHHHHHHHCHHHHHHHHHEECCCCCCCCCCCCHHCCCC
>Mature Secondary Structure
MNILEGFQSALQSVKSNKLRSFLTMLGIIIGISSVITIVSIGDGAKQFITGEFENIGTNL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHCCCHHHCCCCE
INMKMSSSPDITIEKRDYFTMDDVKLLKNKISEIEYASPELGLFGKAKVENKMKQASIMA
EEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHEEE
TNEDSKKFYNLKMMHGRYLNEHDLDSRRAVATIDDRTAKHLFNRVDVVGEKIKFNIGDKN
ECCCCHHHEEEEEECCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHCCCEEEEEECCCC
IDLSIIGVFKDPRGNMGDAFGGSNMPGFLTMPLTIVDRLTEDTDIRGVSVMLSDMKNADQ
EEEEEEEEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHCCCHHH
VSNKMIRLIENKHKNRNKYTAEKGFKELESINKVLGVITMVLGAIAAISLLVGGIGVMNI
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLVSVTERTREIGIRKAIGAKTRDIRIQFLMESIILCLIGGSVGTILGILVGKFAGSLIN
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEE
IQIVVSLKVILTAFGFSSAVGIFFGLYPANQAAQLNPIDALRYE
EEEEHHHHHHHHHHCHHHHHHHHHEECCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA