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The map label for this gene is secA [H]

Identifier: 28210087

GI number: 28210087

Start: 310719

End: 313244

Strand: Direct

Name: secA [H]

Synonym: CTC00327

Alternate gene names: 28210087

Gene position: 310719-313244 (Clockwise)

Preceding gene: 28210085

Following gene: 28210088

Centisome position: 11.1

GC content: 31.55

Gene sequence:

>2526_bases
GTGAGGATGAATAAAATGAGGATTTGGGAAAAAATATTTGGCACATATAGTCAAAGAGAACTTAAAAGAGTAATTCCAAT
AGTAGATAAAATAGATAAATTAGACCAAACCATGCAGAAGTTAACAGATGAAGAGTTAAAAAATAAAACAAATGAATTTA
AAGAAAGATTATCAAAAGGAGAAACCTTAGATGATATATTAGTAGAAGCTTTTGCAGTAGCAAGAGAAGCTGCGTGGAGA
GTTGTTAAATTAAAACCTTACAGAGAACAACTAATAGGTGGTATAATTTTGCACCAAGGTAGAATTGCAGAAATGAAAAC
AGGAGAAGGAAAAACATTAGTTGCAACATTACCAGCATATCTCAATGCTCTAAAAGGAGAAGGCGTACATATAGTTACAG
TAAATGATTATCTTGCAAAAAGAGATAAAGAAACTATGGGAGCTATATATGAATTCTTAGGGTTAACTGTAGGGGTTATC
CTCCACGATTTAGAGCATAACGAAAGACAAGAAGCATATAATTGTGATATTACTTATGGAACCAATAGTGAACTTGGATT
TGATTATTTAAGAGATAATATGGTTGTTTATAAAGAAGAGAGAGTTCAAAGGAAATTAAACTTTTCCATAGTAGACGAAG
TGGATTCCATACTAATAGACGAAGCGAGAACTCCTCTTATAATATCAGGACAAGGAGAAAAGTCTACAGAGTTTTATAAA
GTAGCAGACTACTTTGCCAAATCCTTAATAAAAGAAGAAGACTTTACTGTAGATGAAAAAGCTAGTGCAGTTATGCTAAC
AGATAAAGGTATAGAAAAAGCAGAAGCATATTTTAAGTTGGAAAACTATGCTGATCCAGAAAATATGGAAATACAGCATC
ATGTGGTTCAAGCATTAAAGGCAAACTATTCCATGAAAAAAGATACAGATTACATGGTAAGAGATGGGGAAGTATTAATA
GTAGATGAGTTCACAGGAAGAGTTATGGACGGTAGAAGATATAGTGATGGTCTTCACCAAGCTATTGAAGCTAAAGAAGG
CGTAAATGTAGAAAGAGAATCAAAAACTCTAGCAACTATAACTTATCAAAATTTCTTTAGAATGTATGATAAATTATCTG
GTATGACAGGTACAGCACAAACAGAAGAAGTAGAATTTAGAGAAATATACGGACTAGACGTTGTAGTTATACCTACTCAT
AAACCAGTTTTAAGAATAGATAATTCTGATGTAGTTTATAAATCAGAAAAAGGAAAATATATGGCCATAGTTGATGAGAT
TGTAGAAACTCATAAAAAAGGTCAGCCAGTGCTTGTGGGTACTGTTAGCATAGAAAAATCTGAGCTTATATCAGAAATGC
TTAAAAGAAAAGGAGTACCACATCAAGTATTAAATGCTAAATATCATGAAAAAGAAGCAGAAATAGTATCCCATGCTGGG
GAATATGGTATGGTTACTATTGCAACAAATATGGCAGGACGTGGTACTGACATTAAGCTTGAAGAAGAGGTAATTAAGGC
TGGTGGATTAAAGATAATAGGAACAGAAAGACATGAATCCAGAAGAATCGATAATCAATTAAGAGGACGTTCAGGACGTC
AAGGGGATCCTGGAGCATCTAGATTCTATGTTTCATTGGAAGATGATTTAATGAGAATATTTGGTTCTGATAAACTAAAA
GGTATAGTTGAAAAACTAGGACTTGGTGATGATGAAGCTATAGAAAGTAAAATGGTAAGCAATGCTATAGAAAATGCACA
AAAGAAAGTTGAAGGAAATAACTTTGACATAAGAAAGACATTAATTCAATATGATGATGTTATAAATAAACAAAGAGAAA
TAATTTATAAACAAAGATCTGAAGTATTAGAAGGTGCAGACTTGAAAGATCAGATACAAGAGATGATAAGAGATGTTATA
AACTCAGTTGTAGATTCTCATATATCTGATATAGAAGAAGAGTTTAAAGAAGAACTTGATAAACTTATTAAGTTTTTAGA
AGATATATTCTTGCCTAAAGACTATATAAAAGTAGAACACTTAGAAAATTTATCTAATGATGAAATAAAAGAAAAATTAT
ATGATATAGCTAAAAATATATACACAGATAAAGAAGAAGAATTTGAATCAGAACAAATGAGAGATATAGAAAGAGTTATT
CTTTTAAGGGTAGTAGACACTAAGTGGATGGATCATATTGATAATATGGATCACTTAAAGCAAGGTATAGGCTTAAGAGC
ATATAAACAACAAGATCCAGTTCAAGCGTATCAATTTGAAGGAAGTCAAATGTTTGACGAAATGATATATAATATAAAAG
TTGATACAGTTAGATATTTATTTAGAGTGCAAATAGAGAAAGCTCCAGAAAGGGAACAAGTTGCAAAGGAAACTTCAACT
AACCAAGGTGGAGATGATACATTAAAAAAACAGCCTATAAAAAAAGAGCCTAAGATAGGTAGAAATGATCTATGTCCTTG
TGGTAGTGGGAAGAAATATAAAAATTGTTGCGGAAGAGAAGTTTAA

Upstream 100 bases:

>100_bases
TAGAGAATAATAAAATAGCTTACATTATATAATTAGTTGAAGAGGGTTTAATTAGATGTTATAATCTATTAGGTATATAA
TAATAAGAAATTTTATAATA

Downstream 100 bases:

>100_bases
ACATACAAAATGGAGGAGTAGAATTACTTCTCCATGCTTATTTTATTATATAAAGGGAGATGATTAAAGTGTTATTGCAG
TTAGAAGAAGCTGTAAAAGA

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 841; Mature: 841

Protein sequence:

>841_residues
MRMNKMRIWEKIFGTYSQRELKRVIPIVDKIDKLDQTMQKLTDEELKNKTNEFKERLSKGETLDDILVEAFAVAREAAWR
VVKLKPYREQLIGGIILHQGRIAEMKTGEGKTLVATLPAYLNALKGEGVHIVTVNDYLAKRDKETMGAIYEFLGLTVGVI
LHDLEHNERQEAYNCDITYGTNSELGFDYLRDNMVVYKEERVQRKLNFSIVDEVDSILIDEARTPLIISGQGEKSTEFYK
VADYFAKSLIKEEDFTVDEKASAVMLTDKGIEKAEAYFKLENYADPENMEIQHHVVQALKANYSMKKDTDYMVRDGEVLI
VDEFTGRVMDGRRYSDGLHQAIEAKEGVNVERESKTLATITYQNFFRMYDKLSGMTGTAQTEEVEFREIYGLDVVVIPTH
KPVLRIDNSDVVYKSEKGKYMAIVDEIVETHKKGQPVLVGTVSIEKSELISEMLKRKGVPHQVLNAKYHEKEAEIVSHAG
EYGMVTIATNMAGRGTDIKLEEEVIKAGGLKIIGTERHESRRIDNQLRGRSGRQGDPGASRFYVSLEDDLMRIFGSDKLK
GIVEKLGLGDDEAIESKMVSNAIENAQKKVEGNNFDIRKTLIQYDDVINKQREIIYKQRSEVLEGADLKDQIQEMIRDVI
NSVVDSHISDIEEEFKEELDKLIKFLEDIFLPKDYIKVEHLENLSNDEIKEKLYDIAKNIYTDKEEEFESEQMRDIERVI
LLRVVDTKWMDHIDNMDHLKQGIGLRAYKQQDPVQAYQFEGSQMFDEMIYNIKVDTVRYLFRVQIEKAPEREQVAKETST
NQGGDDTLKKQPIKKEPKIGRNDLCPCGSGKKYKNCCGREV

Sequences:

>Translated_841_residues
MRMNKMRIWEKIFGTYSQRELKRVIPIVDKIDKLDQTMQKLTDEELKNKTNEFKERLSKGETLDDILVEAFAVAREAAWR
VVKLKPYREQLIGGIILHQGRIAEMKTGEGKTLVATLPAYLNALKGEGVHIVTVNDYLAKRDKETMGAIYEFLGLTVGVI
LHDLEHNERQEAYNCDITYGTNSELGFDYLRDNMVVYKEERVQRKLNFSIVDEVDSILIDEARTPLIISGQGEKSTEFYK
VADYFAKSLIKEEDFTVDEKASAVMLTDKGIEKAEAYFKLENYADPENMEIQHHVVQALKANYSMKKDTDYMVRDGEVLI
VDEFTGRVMDGRRYSDGLHQAIEAKEGVNVERESKTLATITYQNFFRMYDKLSGMTGTAQTEEVEFREIYGLDVVVIPTH
KPVLRIDNSDVVYKSEKGKYMAIVDEIVETHKKGQPVLVGTVSIEKSELISEMLKRKGVPHQVLNAKYHEKEAEIVSHAG
EYGMVTIATNMAGRGTDIKLEEEVIKAGGLKIIGTERHESRRIDNQLRGRSGRQGDPGASRFYVSLEDDLMRIFGSDKLK
GIVEKLGLGDDEAIESKMVSNAIENAQKKVEGNNFDIRKTLIQYDDVINKQREIIYKQRSEVLEGADLKDQIQEMIRDVI
NSVVDSHISDIEEEFKEELDKLIKFLEDIFLPKDYIKVEHLENLSNDEIKEKLYDIAKNIYTDKEEEFESEQMRDIERVI
LLRVVDTKWMDHIDNMDHLKQGIGLRAYKQQDPVQAYQFEGSQMFDEMIYNIKVDTVRYLFRVQIEKAPEREQVAKETST
NQGGDDTLKKQPIKKEPKIGRNDLCPCGSGKKYKNCCGREV
>Mature_841_residues
MRMNKMRIWEKIFGTYSQRELKRVIPIVDKIDKLDQTMQKLTDEELKNKTNEFKERLSKGETLDDILVEAFAVAREAAWR
VVKLKPYREQLIGGIILHQGRIAEMKTGEGKTLVATLPAYLNALKGEGVHIVTVNDYLAKRDKETMGAIYEFLGLTVGVI
LHDLEHNERQEAYNCDITYGTNSELGFDYLRDNMVVYKEERVQRKLNFSIVDEVDSILIDEARTPLIISGQGEKSTEFYK
VADYFAKSLIKEEDFTVDEKASAVMLTDKGIEKAEAYFKLENYADPENMEIQHHVVQALKANYSMKKDTDYMVRDGEVLI
VDEFTGRVMDGRRYSDGLHQAIEAKEGVNVERESKTLATITYQNFFRMYDKLSGMTGTAQTEEVEFREIYGLDVVVIPTH
KPVLRIDNSDVVYKSEKGKYMAIVDEIVETHKKGQPVLVGTVSIEKSELISEMLKRKGVPHQVLNAKYHEKEAEIVSHAG
EYGMVTIATNMAGRGTDIKLEEEVIKAGGLKIIGTERHESRRIDNQLRGRSGRQGDPGASRFYVSLEDDLMRIFGSDKLK
GIVEKLGLGDDEAIESKMVSNAIENAQKKVEGNNFDIRKTLIQYDDVINKQREIIYKQRSEVLEGADLKDQIQEMIRDVI
NSVVDSHISDIEEEFKEELDKLIKFLEDIFLPKDYIKVEHLENLSNDEIKEKLYDIAKNIYTDKEEEFESEQMRDIERVI
LLRVVDTKWMDHIDNMDHLKQGIGLRAYKQQDPVQAYQFEGSQMFDEMIYNIKVDTVRYLFRVQIEKAPEREQVAKETST
NQGGDDTLKKQPIKKEPKIGRNDLCPCGSGKKYKNCCGREV

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family [H]

Homologues:

Organism=Escherichia coli, GI1786287, Length=899, Percent_Identity=48.8320355951057, Blast_Score=837, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004027
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116 [H]

Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW [H]

EC number: NA

Molecular weight: Translated: 96628; Mature: 96628

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS01312 SECA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMNKMRIWEKIFGTYSQRELKRVIPIVDKIDKLDQTMQKLTDEELKNKTNEFKERLSKG
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ETLDDILVEAFAVAREAAWRVVKLKPYREQLIGGIILHQGRIAEMKTGEGKTLVATLPAY
CCHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEHHHH
LNALKGEGVHIVTVNDYLAKRDKETMGAIYEFLGLTVGVILHDLEHNERQEAYNCDITYG
HHHHCCCCEEEEEECHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEECEEEEC
TNSELGFDYLRDNMVVYKEERVQRKLNFSIVDEVDSILIDEARTPLIISGQGEKSTEFYK
CCCCCCHHHHHCCEEEEHHHHHHHHHCHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHH
VADYFAKSLIKEEDFTVDEKASAVMLTDKGIEKAEAYFKLENYADPENMEIQHHVVQALK
HHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
ANYSMKKDTDYMVRDGEVLIVDEFTGRVMDGRRYSDGLHQAIEAKEGVNVERESKTLATI
HCCCCCCCCCCEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEH
TYQNFFRMYDKLSGMTGTAQTEEVEFREIYGLDVVVIPTHKPVLRIDNSDVVYKSEKGKY
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCEEEEECCCCCEEEECCCCEEEECCCCCC
MAIVDEIVETHKKGQPVLVGTVSIEKSELISEMLKRKGVPHQVLNAKYHEKEAEIVSHAG
HHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHCCC
EYGMVTIATNMAGRGTDIKLEEEVIKAGGLKIIGTERHESRRIDNQLRGRSGRQGDPGAS
CCCEEEEEECCCCCCCCCCHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCC
RFYVSLEDDLMRIFGSDKLKGIVEKLGLGDDEAIESKMVSNAIENAQKKVEGNNFDIRKT
EEEEEEHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LIQYDDVINKQREIIYKQRSEVLEGADLKDQIQEMIRDVINSVVDSHISDIEEEFKEELD
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLIKFLEDIFLPKDYIKVEHLENLSNDEIKEKLYDIAKNIYTDKEEEFESEQMRDIERVI
HHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LLRVVDTKWMDHIDNMDHLKQGIGLRAYKQQDPVQAYQFEGSQMFDEMIYNIKVDTVRYL
HHHHHHHHHHHHHCCHHHHHHCCCCEECCCCCCCHHHHCCCHHHHHHHHHHCHHHHHHHH
FRVQIEKAPEREQVAKETSTNQGGDDTLKKQPIKKEPKIGRNDLCPCGSGKKYKNCCGRE
HHHHHHCCCCHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCC
V
C
>Mature Secondary Structure
MRMNKMRIWEKIFGTYSQRELKRVIPIVDKIDKLDQTMQKLTDEELKNKTNEFKERLSKG
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ETLDDILVEAFAVAREAAWRVVKLKPYREQLIGGIILHQGRIAEMKTGEGKTLVATLPAY
CCHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEHHHH
LNALKGEGVHIVTVNDYLAKRDKETMGAIYEFLGLTVGVILHDLEHNERQEAYNCDITYG
HHHHCCCCEEEEEECHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEECEEEEC
TNSELGFDYLRDNMVVYKEERVQRKLNFSIVDEVDSILIDEARTPLIISGQGEKSTEFYK
CCCCCCHHHHHCCEEEEHHHHHHHHHCHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHH
VADYFAKSLIKEEDFTVDEKASAVMLTDKGIEKAEAYFKLENYADPENMEIQHHVVQALK
HHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
ANYSMKKDTDYMVRDGEVLIVDEFTGRVMDGRRYSDGLHQAIEAKEGVNVERESKTLATI
HCCCCCCCCCCEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEH
TYQNFFRMYDKLSGMTGTAQTEEVEFREIYGLDVVVIPTHKPVLRIDNSDVVYKSEKGKY
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCEEEEECCCCCEEEECCCCEEEECCCCCC
MAIVDEIVETHKKGQPVLVGTVSIEKSELISEMLKRKGVPHQVLNAKYHEKEAEIVSHAG
HHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHCCC
EYGMVTIATNMAGRGTDIKLEEEVIKAGGLKIIGTERHESRRIDNQLRGRSGRQGDPGAS
CCCEEEEEECCCCCCCCCCHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCC
RFYVSLEDDLMRIFGSDKLKGIVEKLGLGDDEAIESKMVSNAIENAQKKVEGNNFDIRKT
EEEEEEHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LIQYDDVINKQREIIYKQRSEVLEGADLKDQIQEMIRDVINSVVDSHISDIEEEFKEELD
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLIKFLEDIFLPKDYIKVEHLENLSNDEIKEKLYDIAKNIYTDKEEEFESEQMRDIERVI
HHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LLRVVDTKWMDHIDNMDHLKQGIGLRAYKQQDPVQAYQFEGSQMFDEMIYNIKVDTVRYL
HHHHHHHHHHHHHCCHHHHHHCCCCEECCCCCCCHHHHCCCHHHHHHHHHHCHHHHHHHH
FRVQIEKAPEREQVAKETSTNQGGDDTLKKQPIKKEPKIGRNDLCPCGSGKKYKNCCGRE
HHHHHHCCCCHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]