Click here to switch to the map view.

The map label for this gene is wecB [C]

Identifier: 28210072

GI number: 28210072

Start: 293135

End: 294298

Strand: Direct

Name: wecB [C]

Synonym: CTC00311

Alternate gene names: 28210072

Gene position: 293135-294298 (Clockwise)

Preceding gene: 28210071

Following gene: 28210073

Centisome position: 10.47

GC content: 29.73

Gene sequence:

>1164_bases
TTGGAGGTAAGGTTTATGAAAAAAACAAAGATAATGACTATATTTGGGACTAGACCTGAGGCTATAAAGATGGCTCCATT
AGTAAAGGAGATAGAAAAAAGAGAGGAACTTTGTAGTAAAGTTTGCGTTACGGCTCAACATAGAGAAATGTTGGATCAAG
TTTTAGATCTATTTCAAATTAAGCCAAATTATGATTTGGATATAATGGCAAAAGGACAAACTTTAACAGATATAACAATG
AAAAGCCTTAAGGGTTTAGAAGTCGTATTTGCTAAGGAGAAGCCAGATTTAGTTTTAGTTCATGGAGATACTACTACAAC
TTTTGCAGGAGCGTTAGCTGCTTTTTATCAACAAATAAAGATAGGTCATGTAGAAGCAGGACTAAGAACCTTTAATAAGT
ACTTTCCTTATCCAGAAGAAATGAATAGAAAATTATCCGGTGCTATGGCGGATTTACATTTTGCTCCAACAAAGGGATCA
AGAGAGAATCTTTTAAAGGAAGGTATAGCTGATAATGACATATATATTACAGGAAATACTGTAATAGATGCTATGGAATT
TACAGTAGAAGATAACTATACTTTTAAAAATGAAGTATTAAATAAAATAGATTATAAGAATAAAAAAGTTATAATGGTTA
CTGCACACAGAAGAGAAAATTGGGGTGAAGGAATAGAAAATATATGTAAAGGATTAAAAGAAATAGTTGAAAATAATGAA
GAAGTAGAAATAGTATACTTAGTTCATTTAAACCCAATTGTTAAAGATGTGGTATATAAATATTTAGGTGAAATGGATAG
AGTTCATTTATTAAATCCTTTAGATACTAAAGAAACCCATAATTTAATGAATAAATGTTATATGGTTATGACTGATTCAG
GAGGACTTCAAGAGGAAGCACCTCATTTAGGAAAGCCTGTTTTAGTTTTAAGAGATGTAACTGAAAGACCTGAAGCGGTT
ACAGCAGGTACAGTAAAACTATTAGGAACAAATAAAAATCTTATAGTGAGTGAAGCTAATAAAATAATAAGAGATAAAGA
AGAATACAATAATATAAGTAGAGCAATAAATCCATATGGAGATGGATATGCTTCAAGAAGAATAGTAGACTCTATACTAT
ATTATTTCAAGTATTTAGATAAAAGACCTAATAATTTTATATAA

Upstream 100 bases:

>100_bases
TCAGAACTCATATTTTTTACTTGCAGTTGTTGTAATGATAATAATGGCAATAGCTTGGAGATATGGCTTTTTTAAGCACA
AGGAATAGTACATAATTAAC

Downstream 100 bases:

>100_bases
AGTTTGTGTTTTTTTTAACAAAAATATATTGAAAAATTTTTAATATGGGGTTATAATATAAATAGTTTAAAAGAAATTTG
TTAATTTTTTAACTAAAGGT

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MEVRFMKKTKIMTIFGTRPEAIKMAPLVKEIEKREELCSKVCVTAQHREMLDQVLDLFQIKPNYDLDIMAKGQTLTDITM
KSLKGLEVVFAKEKPDLVLVHGDTTTTFAGALAAFYQQIKIGHVEAGLRTFNKYFPYPEEMNRKLSGAMADLHFAPTKGS
RENLLKEGIADNDIYITGNTVIDAMEFTVEDNYTFKNEVLNKIDYKNKKVIMVTAHRRENWGEGIENICKGLKEIVENNE
EVEIVYLVHLNPIVKDVVYKYLGEMDRVHLLNPLDTKETHNLMNKCYMVMTDSGGLQEEAPHLGKPVLVLRDVTERPEAV
TAGTVKLLGTNKNLIVSEANKIIRDKEEYNNISRAINPYGDGYASRRIVDSILYYFKYLDKRPNNFI

Sequences:

>Translated_387_residues
MEVRFMKKTKIMTIFGTRPEAIKMAPLVKEIEKREELCSKVCVTAQHREMLDQVLDLFQIKPNYDLDIMAKGQTLTDITM
KSLKGLEVVFAKEKPDLVLVHGDTTTTFAGALAAFYQQIKIGHVEAGLRTFNKYFPYPEEMNRKLSGAMADLHFAPTKGS
RENLLKEGIADNDIYITGNTVIDAMEFTVEDNYTFKNEVLNKIDYKNKKVIMVTAHRRENWGEGIENICKGLKEIVENNE
EVEIVYLVHLNPIVKDVVYKYLGEMDRVHLLNPLDTKETHNLMNKCYMVMTDSGGLQEEAPHLGKPVLVLRDVTERPEAV
TAGTVKLLGTNKNLIVSEANKIIRDKEEYNNISRAINPYGDGYASRRIVDSILYYFKYLDKRPNNFI
>Mature_387_residues
MEVRFMKKTKIMTIFGTRPEAIKMAPLVKEIEKREELCSKVCVTAQHREMLDQVLDLFQIKPNYDLDIMAKGQTLTDITM
KSLKGLEVVFAKEKPDLVLVHGDTTTTFAGALAAFYQQIKIGHVEAGLRTFNKYFPYPEEMNRKLSGAMADLHFAPTKGS
RENLLKEGIADNDIYITGNTVIDAMEFTVEDNYTFKNEVLNKIDYKNKKVIMVTAHRRENWGEGIENICKGLKEIVENNE
EVEIVYLVHLNPIVKDVVYKYLGEMDRVHLLNPLDTKETHNLMNKCYMVMTDSGGLQEEAPHLGKPVLVLRDVTERPEAV
TAGTVKLLGTNKNLIVSEANKIIRDKEEYNNISRAINPYGDGYASRRIVDSILYYFKYLDKRPNNFI

Specific function: Catalyzes The Reversible Epimerization At C-2 Of UDP-N- Acetylglucosamine (UDP-Glcnac) And Thereby Provides Bacteria With UDP-N-Acetylmannosamine (UDP-Mannac), The Activated Donor Of Mannac Residues. Also Involved In Bacteriophage N4 Adsorption. [C]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=368, Percent_Identity=55.1630434782609, Blast_Score=398, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 44254; Mature: 44254

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVRFMKKTKIMTIFGTRPEAIKMAPLVKEIEKREELCSKVCVTAQHREMLDQVLDLFQI
CCCEEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KPNYDLDIMAKGQTLTDITMKSLKGLEVVFAKEKPDLVLVHGDTTTTFAGALAAFYQQIK
CCCCCEEEEECCCCHHHHHHHHCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHH
IGHVEAGLRTFNKYFPYPEEMNRKLSGAMADLHFAPTKGSRENLLKEGIADNDIYITGNT
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEECCCCCCHHHHHHCCCCCCCEEEECCC
VIDAMEFTVEDNYTFKNEVLNKIDYKNKKVIMVTAHRRENWGEGIENICKGLKEIVENNE
EEEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCC
EVEIVYLVHLNPIVKDVVYKYLGEMDRVHLLNPLDTKETHNLMNKCYMVMTDSGGLQEEA
CEEEEEEEECCHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHEEEEEECCCCCCCCC
PHLGKPVLVLRDVTERPEAVTAGTVKLLGTNKNLIVSEANKIIRDKEEYNNISRAINPYG
CCCCCCEEEEECCCCCCCCEECCEEEEEECCCCEEEHHHHHHHHCHHHHHHHHHHCCCCC
DGYASRRIVDSILYYFKYLDKRPNNFI
CCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEVRFMKKTKIMTIFGTRPEAIKMAPLVKEIEKREELCSKVCVTAQHREMLDQVLDLFQI
CCCEEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KPNYDLDIMAKGQTLTDITMKSLKGLEVVFAKEKPDLVLVHGDTTTTFAGALAAFYQQIK
CCCCCEEEEECCCCHHHHHHHHCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHH
IGHVEAGLRTFNKYFPYPEEMNRKLSGAMADLHFAPTKGSRENLLKEGIADNDIYITGNT
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEECCCCCCHHHHHHCCCCCCCEEEECCC
VIDAMEFTVEDNYTFKNEVLNKIDYKNKKVIMVTAHRRENWGEGIENICKGLKEIVENNE
EEEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCC
EVEIVYLVHLNPIVKDVVYKYLGEMDRVHLLNPLDTKETHNLMNKCYMVMTDSGGLQEEA
CEEEEEEEECCHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHEEEEEECCCCCCCCC
PHLGKPVLVLRDVTERPEAVTAGTVKLLGTNKNLIVSEANKIIRDKEEYNNISRAINPYG
CCCCCCEEEEECCCCCCCCEECCEEEEEECCCCEEEHHHHHHHHCHHHHHHHHHHCCCCC
DGYASRRIVDSILYYFKYLDKRPNNFI
CCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286; 7867955 [H]