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The map label for this gene is gamP [H]

Identifier: 28210041

GI number: 28210041

Start: 258330

End: 260339

Strand: Direct

Name: gamP [H]

Synonym: CTC00278

Alternate gene names: 28210041

Gene position: 258330-260339 (Clockwise)

Preceding gene: 28210040

Following gene: 28210042

Centisome position: 9.23

GC content: 32.29

Gene sequence:

>2010_bases
ATGAAAAAGCTATTTAGTATATTACAAAAGATAGGTAAATCTCTAATGCTTCCCGTGTCAGTATTGCCTGCAGCGGGAAT
ACTTTTAAGATTAGGGCAGCCGGATCTTTTAAATATGCCATATTTAGCTACAGCAGGAGATGCCATATTTACAAATCTTC
CAATGATTTTTGCAGTTGGTGTAGCTATTGGATTTTCAGGAGGAGAGGGAACGGCAGCTTTGGCAGCGGTAGTAGGTCAA
TTTATTCTACAAGGAATAATTAAAGTTGCTGGAGATAATTTTGCTCAAATTGCAGCAGAGCAAATAGCCAAAGCTCAGGG
AATGGCATTTGACATATTTAAAAATTCAGCGGAGTATACTGAGATAGTAAGATTAAATCAAATAAATATGGGGGTATTCG
GCGGTATTATAATAGGATTGACAGCAGCGATTTTATATAATAAATATCATAATATAAAACTACCACAAGCTTTGGGTTTT
TTTGCAGGTAAGAGGTTTGTCCCTATAGTTACTTCTATTGCATCATTAATTATTGCAATTATAGGGGTTAAGGTTTGGCC
GGAACTACAAAAGGGTATAGATGTGTTTGCACGTTGGGCTAGCACCTCTCCCTATGGTCCAGCTCTTTATGCATCTGGAA
AAAGGCTACTTATACCTGTAGGACTTCATCATATGTACTATCCACCGTTCTTATACCAGTTTGGAGAATATGTAGTAGAT
GGGGTATCTTATTTAGGAGATTTTGCAAGATTTTATCATGGAGATCCTAGCGCAGGTATATTTATGGCATCAGAATATCC
TAATATAATGTTTGGACTTCCAGGAGCAGCTCTGGCAATGGTTCTTACTGCTAAGAAAGAAAATAGAAAAGCAGTGGCAG
GAATGATGGCATCAGCAGCATTAGTTGCTTTTGTTACCGGGATAACAGAACCAATTGAATTTTCGTTTATATTTGTTGCA
CCAATGTTATTTGTGTTTCATGTTTTAGCAGCTTTTATAGGAGGATTAGTAACAAAAATTTTAGATATAAGATTAGGATA
TACATTTTCAGCTTCTGCAATAGATTATATATTAGGTTTTAAATTTACTGGAAATGCTCTATTAATTTGGCCTGTAGGAA
TAGCATTTTTTATTTTATATTTTGTAGTTTTTTATTTTGTAATAAAGAAATTTAATATTAAAACACCTGGTAGAGAAGAC
AATAAAGCATCAAAAGAACAATTTATAATTAAGGATTTAAAAAGGGATGATAGAGCATTTAAAGTTTTAGAGGCTTTAGG
TGGAAAAAATAATATAAAAGAATTAGATGCTTGTATGACAAGGCTTAGATTAAATTTAGTAGATACTTCAAAGGTGGATA
AAAATACACTTAAAGCTTTAGGATCAGCTGGAGTAATGGAGGCCGGAAATAGTGTTCAAGTAATATTTGGAACAGATGCA
GAAAGAATAAAGGATGATATTAAAAATGTTATTAATAATTCATATGAGCCTTTAGAAGAAAAAGAGAATTATAATGAAAA
AGAAGATTTCAAAGATGACCTCAAAAAAAATAATATAAAAGAAGAAATTATTTTAACACCAATAGAAGGTGAAGTAGTAG
AATTAGAAAAAGTTCCAGATGAGGTTTTTTCTAAAAAAATGCTGGGGGATGGTTTTGCTGTAGAAATAAAAGGAGATAAG
GTCTATGCTCCAATAGAGGGAGAGATATCTGTTATATTCCCAACAAAACATGCTATTGCAATAACCACAAATAATGGTCT
AGAAATATTAATTCACGTTGGTATAGATACTGTTGAACTTCAAGGTGAAGGTTTTATTTCTCATGTTAAACAAGGTGATA
CAGTTAAAAAAGGAGATCTTCTATTAACTGTAGATAAAGAGTTTATAAAAAATAAGGGAAAAAGCCTAATGACTCCTGTT
ATAGTAACTAATATGGAGAAAGTAGAATCAATAGAAATATTTAAGGGACAAAACACAAATAAAAAAGCTGCTAATGTAAA
AATAAAATAG

Upstream 100 bases:

>100_bases
TCCAATTAGTAGAAGATATAGTTACTATATTCACTAACTTTGGTATAGAATCAGAGATACTCGTGTTTTGTTTTAAAAAA
ATAATATAGGAGGAATACCA

Downstream 100 bases:

>100_bases
TATATAATATTATAATTTAAGGTTGCTATTCATTAAGCAAAATAGCAATCTTTTTGTATCATCCTATATTTTTATTCATA
TTATAGAATTAAAATAATAT

Product: PTS system, glucose-specific IIABC component

Products: NA

Alternate protein names: Glucosamine permease IIC component; PTS system glucosamine-specific EIIC component; Glucosamine-specific phosphotransferase enzyme IIB component; PTS system glucosamine-specific EIIB component; Glucosamine-specific phosphotransferase enzyme IIA component; PTS system glucosamine-specific EIIA component [H]

Number of amino acids: Translated: 669; Mature: 669

Protein sequence:

>669_residues
MKKLFSILQKIGKSLMLPVSVLPAAGILLRLGQPDLLNMPYLATAGDAIFTNLPMIFAVGVAIGFSGGEGTAALAAVVGQ
FILQGIIKVAGDNFAQIAAEQIAKAQGMAFDIFKNSAEYTEIVRLNQINMGVFGGIIIGLTAAILYNKYHNIKLPQALGF
FAGKRFVPIVTSIASLIIAIIGVKVWPELQKGIDVFARWASTSPYGPALYASGKRLLIPVGLHHMYYPPFLYQFGEYVVD
GVSYLGDFARFYHGDPSAGIFMASEYPNIMFGLPGAALAMVLTAKKENRKAVAGMMASAALVAFVTGITEPIEFSFIFVA
PMLFVFHVLAAFIGGLVTKILDIRLGYTFSASAIDYILGFKFTGNALLIWPVGIAFFILYFVVFYFVIKKFNIKTPGRED
NKASKEQFIIKDLKRDDRAFKVLEALGGKNNIKELDACMTRLRLNLVDTSKVDKNTLKALGSAGVMEAGNSVQVIFGTDA
ERIKDDIKNVINNSYEPLEEKENYNEKEDFKDDLKKNNIKEEIILTPIEGEVVELEKVPDEVFSKKMLGDGFAVEIKGDK
VYAPIEGEISVIFPTKHAIAITTNNGLEILIHVGIDTVELQGEGFISHVKQGDTVKKGDLLLTVDKEFIKNKGKSLMTPV
IVTNMEKVESIEIFKGQNTNKKAANVKIK

Sequences:

>Translated_669_residues
MKKLFSILQKIGKSLMLPVSVLPAAGILLRLGQPDLLNMPYLATAGDAIFTNLPMIFAVGVAIGFSGGEGTAALAAVVGQ
FILQGIIKVAGDNFAQIAAEQIAKAQGMAFDIFKNSAEYTEIVRLNQINMGVFGGIIIGLTAAILYNKYHNIKLPQALGF
FAGKRFVPIVTSIASLIIAIIGVKVWPELQKGIDVFARWASTSPYGPALYASGKRLLIPVGLHHMYYPPFLYQFGEYVVD
GVSYLGDFARFYHGDPSAGIFMASEYPNIMFGLPGAALAMVLTAKKENRKAVAGMMASAALVAFVTGITEPIEFSFIFVA
PMLFVFHVLAAFIGGLVTKILDIRLGYTFSASAIDYILGFKFTGNALLIWPVGIAFFILYFVVFYFVIKKFNIKTPGRED
NKASKEQFIIKDLKRDDRAFKVLEALGGKNNIKELDACMTRLRLNLVDTSKVDKNTLKALGSAGVMEAGNSVQVIFGTDA
ERIKDDIKNVINNSYEPLEEKENYNEKEDFKDDLKKNNIKEEIILTPIEGEVVELEKVPDEVFSKKMLGDGFAVEIKGDK
VYAPIEGEISVIFPTKHAIAITTNNGLEILIHVGIDTVELQGEGFISHVKQGDTVKKGDLLLTVDKEFIKNKGKSLMTPV
IVTNMEKVESIEIFKGQNTNKKAANVKIK
>Mature_669_residues
MKKLFSILQKIGKSLMLPVSVLPAAGILLRLGQPDLLNMPYLATAGDAIFTNLPMIFAVGVAIGFSGGEGTAALAAVVGQ
FILQGIIKVAGDNFAQIAAEQIAKAQGMAFDIFKNSAEYTEIVRLNQINMGVFGGIIIGLTAAILYNKYHNIKLPQALGF
FAGKRFVPIVTSIASLIIAIIGVKVWPELQKGIDVFARWASTSPYGPALYASGKRLLIPVGLHHMYYPPFLYQFGEYVVD
GVSYLGDFARFYHGDPSAGIFMASEYPNIMFGLPGAALAMVLTAKKENRKAVAGMMASAALVAFVTGITEPIEFSFIFVA
PMLFVFHVLAAFIGGLVTKILDIRLGYTFSASAIDYILGFKFTGNALLIWPVGIAFFILYFVVFYFVIKKFNIKTPGRED
NKASKEQFIIKDLKRDDRAFKVLEALGGKNNIKELDACMTRLRLNLVDTSKVDKNTLKALGSAGVMEAGNSVQVIFGTDA
ERIKDDIKNVINNSYEPLEEKENYNEKEDFKDDLKKNNIKEEIILTPIEGEVVELEKVPDEVFSKKMLGDGFAVEIKGDK
VYAPIEGEISVIFPTKHAIAITTNNGLEILIHVGIDTVELQGEGFISHVKQGDTVKKGDLLLTVDKEFIKNKGKSLMTPV
IVTNMEKVESIEIFKGQNTNKKAANVKIK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786894, Length=673, Percent_Identity=38.7815750371471, Blast_Score=431, Evalue=1e-121,
Organism=Escherichia coli, GI1787343, Length=505, Percent_Identity=42.5742574257426, Blast_Score=369, Evalue=1e-103,
Organism=Escherichia coli, GI1787908, Length=531, Percent_Identity=32.015065913371, Blast_Score=245, Evalue=8e-66,
Organism=Escherichia coli, GI1788757, Length=158, Percent_Identity=40.5063291139241, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI1790159, Length=123, Percent_Identity=43.9024390243902, Blast_Score=108, Evalue=9e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 73239; Mature: 73239

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLFSILQKIGKSLMLPVSVLPAAGILLRLGQPDLLNMPYLATAGDAIFTNLPMIFAVG
CHHHHHHHHHHHHHHCCCHHHHHHCCCEEECCCCCCCCCCCHHCCCCHHHHCCHHHHHHH
VAIGFSGGEGTAALAAVVGQFILQGIIKVAGDNFAQIAAEQIAKAQGMAFDIFKNSAEYT
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECCCCCHHH
EIVRLNQINMGVFGGIIIGLTAAILYNKYHNIKLPQALGFFAGKRFVPIVTSIASLIIAI
HHHEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
IGVKVWPELQKGIDVFARWASTSPYGPALYASGKRLLIPVGLHHMYYPPFLYQFGEYVVD
HHHHHCHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEECHHHHCCCHHHHHHHHHHHH
GVSYLGDFARFYHGDPSAGIFMASEYPNIMFGLPGAALAMVLTAKKENRKAVAGMMASAA
HHHHHHHHHHHHCCCCCCCEEEECCCCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHH
LVAFVTGITEPIEFSFIFVAPMLFVFHVLAAFIGGLVTKILDIRLGYTFSASAIDYILGF
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHEE
KFTGNALLIWPVGIAFFILYFVVFYFVIKKFNIKTPGREDNKASKEQFIIKDLKRDDRAF
EEECCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCHHHH
KVLEALGGKNNIKELDACMTRLRLNLVDTSKVDKNTLKALGSAGVMEAGNSVQVIFGTDA
HHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHCCCCEEEEEECCCH
ERIKDDIKNVINNSYEPLEEKENYNEKEDFKDDLKKNNIKEEIILTPIEGEVVELEKVPD
HHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCCEEEHHHCCH
EVFSKKMLGDGFAVEIKGDKVYAPIEGEISVIFPTKHAIAITTNNGLEILIHVGIDTVEL
HHHHHHHCCCCEEEEEECCEEEECCCCCEEEEEECCEEEEEEECCCEEEEEEECCEEEEE
QGEGFISHVKQGDTVKKGDLLLTVDKEFIKNKGKSLMTPVIVTNMEKVESIEIFKGQNTN
CCCHHHHHHCCCCCEECCCEEEEECHHHHHCCCCCCCCHHHHCCHHHHHHEEEEECCCCC
KKAANVKIK
CCCCCCEEC
>Mature Secondary Structure
MKKLFSILQKIGKSLMLPVSVLPAAGILLRLGQPDLLNMPYLATAGDAIFTNLPMIFAVG
CHHHHHHHHHHHHHHCCCHHHHHHCCCEEECCCCCCCCCCCHHCCCCHHHHCCHHHHHHH
VAIGFSGGEGTAALAAVVGQFILQGIIKVAGDNFAQIAAEQIAKAQGMAFDIFKNSAEYT
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECCCCCHHH
EIVRLNQINMGVFGGIIIGLTAAILYNKYHNIKLPQALGFFAGKRFVPIVTSIASLIIAI
HHHEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
IGVKVWPELQKGIDVFARWASTSPYGPALYASGKRLLIPVGLHHMYYPPFLYQFGEYVVD
HHHHHCHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEECHHHHCCCHHHHHHHHHHHH
GVSYLGDFARFYHGDPSAGIFMASEYPNIMFGLPGAALAMVLTAKKENRKAVAGMMASAA
HHHHHHHHHHHHCCCCCCCEEEECCCCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHH
LVAFVTGITEPIEFSFIFVAPMLFVFHVLAAFIGGLVTKILDIRLGYTFSASAIDYILGF
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHEE
KFTGNALLIWPVGIAFFILYFVVFYFVIKKFNIKTPGREDNKASKEQFIIKDLKRDDRAF
EEECCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCHHHH
KVLEALGGKNNIKELDACMTRLRLNLVDTSKVDKNTLKALGSAGVMEAGNSVQVIFGTDA
HHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHCCCCEEEEEECCCH
ERIKDDIKNVINNSYEPLEEKENYNEKEDFKDDLKKNNIKEEIILTPIEGEVVELEKVPD
HHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCCEEEHHHCCH
EVFSKKMLGDGFAVEIKGDKVYAPIEGEISVIFPTKHAIAITTNNGLEILIHVGIDTVEL
HHHHHHHCCCCEEEEEECCEEEECCCCCEEEEEECCEEEEEEECCCEEEEEEECCEEEEE
QGEGFISHVKQGDTVKKGDLLLTVDKEFIKNKGKSLMTPVIVTNMEKVESIEIFKGQNTN
CCCHHHHHHCCCCCEECCCEEEEECHHHHHCCCCCCCCHHHHCCHHHHHHEEEEECCCCC
KKAANVKIK
CCCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 7751298 [H]