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The map label for this gene is mrp [H]

Identifier: 28210018

GI number: 28210018

Start: 220842

End: 221684

Strand: Direct

Name: mrp [H]

Synonym: CTC00253

Alternate gene names: 28210018

Gene position: 220842-221684 (Clockwise)

Preceding gene: 28210017

Following gene: 28210021

Centisome position: 7.89

GC content: 32.98

Gene sequence:

>843_bases
ATGAGTAATTGTGATAGTTGTCCAAGTAAAGGAAAGTGCGGCGAAAATAAAGAAGCCTGTTCAAAAGTAGTACCTAAATA
CGGAAATATAAAACACATAATTGGAGTTATAAGTGGTAAAGGTGGCGTAGGTAAATCTACAGTAACCGGAATACTTGCTA
CAAAGCTTAAAAAAGCTGGATATAAAGTTGGGGTATTAGATGCTGATATAACAGGACCATCAATGCCTAGATTTTTTGGC
ATAAATGAAGAAAGAGCATATGCTATGGAAGGTAGAACTAGAGAAGAGGTTAAATTTTTACCGGTAGAAACATCATCAGG
TATAAAGGTTATGTCTCTTAATTTATTAACTGAACATGAAGAGGAACCAGTTATATGGAGAGGACCAGTTGTTACTGGAG
TGCTTACTCAAATGTACACAGATACAGACTGGGGTGAACTTGATTATCTTCTTATAGATATGCCACCAGGAACAGGAGAT
GTAGCACTTACAATTATGCAAAGTATGCCTGTGGAAGGTATGGTAGTTGTTTCAACAGCACAAGATATGGTTTCTATGAT
AGTTAAAAAAGTAATTATAATGGCGGAAAAATTAAATATAAACGTTTTAGGTGTAGTAGAAAATATGTCTTATGTGAAAT
GCAGTTGCGGGGAGAAAATAAATTTATTTAGTAAAAAAACTGCTAAAGAACAAGCTGAATATTTAGAAGTACCTTTAATA
TCAGAACTTCCTGTAAATCTAGATTTAACAGAAAACATGGAAAAAGGTAATGTAGAAAATTACATTGCAAGTTGTGAAGA
GTATGATGAACTATTAAAAGGTTTCATGAATCAAATAAAATAA

Upstream 100 bases:

>100_bases
AATTATTATCTTAAAGCAGAATATGAAAATAGGTCATGGAATGTAGAATGTTTTAATAAAAAGCCTGACAATTTTTAACG
TAAGCAAAGGAGGATTTTTA

Downstream 100 bases:

>100_bases
AGTATAACAAAGTTGGTGAAAATTATTTACCAACTTTGTTATTTTTTAAATACAGTTATAAATAAACGAAACAAGGTAAA
AATAATAAGGAAAATATTTA

Product: MRP protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MSNCDSCPSKGKCGENKEACSKVVPKYGNIKHIIGVISGKGGVGKSTVTGILATKLKKAGYKVGVLDADITGPSMPRFFG
INEERAYAMEGRTREEVKFLPVETSSGIKVMSLNLLTEHEEEPVIWRGPVVTGVLTQMYTDTDWGELDYLLIDMPPGTGD
VALTIMQSMPVEGMVVVSTAQDMVSMIVKKVIIMAEKLNINVLGVVENMSYVKCSCGEKINLFSKKTAKEQAEYLEVPLI
SELPVNLDLTENMEKGNVENYIASCEEYDELLKGFMNQIK

Sequences:

>Translated_280_residues
MSNCDSCPSKGKCGENKEACSKVVPKYGNIKHIIGVISGKGGVGKSTVTGILATKLKKAGYKVGVLDADITGPSMPRFFG
INEERAYAMEGRTREEVKFLPVETSSGIKVMSLNLLTEHEEEPVIWRGPVVTGVLTQMYTDTDWGELDYLLIDMPPGTGD
VALTIMQSMPVEGMVVVSTAQDMVSMIVKKVIIMAEKLNINVLGVVENMSYVKCSCGEKINLFSKKTAKEQAEYLEVPLI
SELPVNLDLTENMEKGNVENYIASCEEYDELLKGFMNQIK
>Mature_279_residues
SNCDSCPSKGKCGENKEACSKVVPKYGNIKHIIGVISGKGGVGKSTVTGILATKLKKAGYKVGVLDADITGPSMPRFFGI
NEERAYAMEGRTREEVKFLPVETSSGIKVMSLNLLTEHEEEPVIWRGPVVTGVLTQMYTDTDWGELDYLLIDMPPGTGDV
ALTIMQSMPVEGMVVVSTAQDMVSMIVKKVIIMAEKLNINVLGVVENMSYVKCSCGEKINLFSKKTAKEQAEYLEVPLIS
ELPVNLDLTENMEKGNVENYIASCEEYDELLKGFMNQIK

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI6912540, Length=233, Percent_Identity=39.9141630901288, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI157384956, Length=244, Percent_Identity=36.8852459016393, Blast_Score=160, Evalue=9e-40,
Organism=Homo sapiens, GI118572611, Length=268, Percent_Identity=33.955223880597, Blast_Score=156, Evalue=2e-38,
Organism=Escherichia coli, GI87082045, Length=233, Percent_Identity=42.4892703862661, Blast_Score=177, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI25143050, Length=290, Percent_Identity=35.1724137931034, Blast_Score=164, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6322188, Length=263, Percent_Identity=41.06463878327, Blast_Score=178, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6321347, Length=280, Percent_Identity=31.4285714285714, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24667611, Length=225, Percent_Identity=42.2222222222222, Blast_Score=168, Evalue=3e-42,
Organism=Drosophila melanogaster, GI221511043, Length=228, Percent_Identity=38.1578947368421, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI19921440, Length=271, Percent_Identity=34.6863468634686, Blast_Score=140, Evalue=9e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR015223
- InterPro:   IPR000808 [H]

Pfam domain/function: PF09140 MipZ; PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 30679; Mature: 30548

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNCDSCPSKGKCGENKEACSKVVPKYGNIKHIIGVISGKGGVGKSTVTGILATKLKKAG
CCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCC
YKVGVLDADITGPSMPRFFGINEERAYAMEGRTREEVKFLPVETSSGIKVMSLNLLTEHE
CEEEEEECCCCCCCCCCEECCCCCCEEEECCCCCCCEEEEEEECCCCCEEEEEEEEECCC
EEPVIWRGPVVTGVLTQMYTDTDWGELDYLLIDMPPGTGDVALTIMQSMPVEGMVVVSTA
CCCEEEECCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCEEEEECH
QDMVSMIVKKVIIMAEKLNINVLGVVENMSYVKCSCGEKINLFSKKTAKEQAEYLEVPLI
HHHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEECCCCEECHHHHHHHHHHHHHHCCCCH
SELPVNLDLTENMEKGNVENYIASCEEYDELLKGFMNQIK
HCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNCDSCPSKGKCGENKEACSKVVPKYGNIKHIIGVISGKGGVGKSTVTGILATKLKKAG
CCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCC
YKVGVLDADITGPSMPRFFGINEERAYAMEGRTREEVKFLPVETSSGIKVMSLNLLTEHE
CEEEEEECCCCCCCCCCEECCCCCCEEEECCCCCCCEEEEEEECCCCCEEEEEEEEECCC
EEPVIWRGPVVTGVLTQMYTDTDWGELDYLLIDMPPGTGDVALTIMQSMPVEGMVVVSTA
CCCEEEECCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCEEEEECH
QDMVSMIVKKVIIMAEKLNINVLGVVENMSYVKCSCGEKINLFSKKTAKEQAEYLEVPLI
HHHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEECCCCEECHHHHHHHHHHHHHHCCCCH
SELPVNLDLTENMEKGNVENYIASCEEYDELLKGFMNQIK
HCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792842; 7559358 [H]