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The map label for this gene is ihfA

Identifier: 28199777

GI number: 28199777

Start: 2240030

End: 2240329

Strand: Reverse

Name: ihfA

Synonym: PD1910

Alternate gene names: 28199777

Gene position: 2240329-2240030 (Counterclockwise)

Preceding gene: 28199778

Following gene: 28199776

Centisome position: 88.91

GC content: 46.0

Gene sequence:

>300_bases
ATGGCATTGACAAAAGCAGAGATGGTAGAACGTTTATTCGATGAAGTCGGCTTGAATAAACGCGAAGCAAAAGAATTTGT
TGATGCCTTCTTCGACTTGTTGCGCGATGCACTGGAACAAGGAAAGGAAATCAAGCTTTCCGGCTTCGGTAACTTTGAAT
TGCGCTGTAAAAATCAGAGACCTGGCCGCAATCCAAAAACCGGAGAAGAAATCCCGATTTCTGCCAGAACAGTGGTTACT
TTCCGATCGGGTCAGAAGCTGAAGGAGAGGGTGGATGCCTATGTTGGATCCAGGCAGTAA

Upstream 100 bases:

>100_bases
CCGTGACGTTGACGACATCATGACGAAGGTTGTCATGGCGATCCAGCAACGACACGACGTGCGGATCCGGTCTTGATGTA
AATAAAGGGGGTACACCAGC

Downstream 100 bases:

>100_bases
CCGAGAACTACCAACGATTCCAGCCAAGCGTTACTTCTCCATTGGTGAAGTTGCTGATTTGTGCGACGTCAAACAGCACG
TATTGCGCTACTGGGAAACC

Product: integration host factor subunit alpha

Products: NA

Alternate protein names: IHF-alpha

Number of amino acids: Translated: 99; Mature: 98

Protein sequence:

>99_residues
MALTKAEMVERLFDEVGLNKREAKEFVDAFFDLLRDALEQGKEIKLSGFGNFELRCKNQRPGRNPKTGEEIPISARTVVT
FRSGQKLKERVDAYVGSRQ

Sequences:

>Translated_99_residues
MALTKAEMVERLFDEVGLNKREAKEFVDAFFDLLRDALEQGKEIKLSGFGNFELRCKNQRPGRNPKTGEEIPISARTVVT
FRSGQKLKERVDAYVGSRQ
>Mature_98_residues
ALTKAEMVERLFDEVGLNKREAKEFVDAFFDLLRDALEQGKEIKLSGFGNFELRCKNQRPGRNPKTGEEIPISARTVVTF
RSGQKLKERVDAYVGSRQ

Specific function: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family

Homologues:

Organism=Escherichia coli, GI1788005, Length=92, Percent_Identity=72.8260869565217, Blast_Score=138, Evalue=7e-35,
Organism=Escherichia coli, GI1786644, Length=90, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=5e-14,
Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=33.7078651685393, Blast_Score=67, Evalue=2e-13,
Organism=Escherichia coli, GI1787141, Length=93, Percent_Identity=32.258064516129, Blast_Score=65, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IHFA_XYLF2 (B2I9P2)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001830687.1
- ProteinModelPortal:   B2I9P2
- SMR:   B2I9P2
- GeneID:   6203371
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_2014
- HOGENOM:   HBG705085
- OMA:   VRGETVK
- ProtClustDB:   PRK00285
- GO:   GO:0006350
- HAMAP:   MF_00380
- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992
- InterPro:   IPR005684
- Gene3D:   G3DSA:4.10.520.10
- PRINTS:   PR01727
- SMART:   SM00411
- TIGRFAMs:   TIGR00987

Pfam domain/function: PF00216 Bac_DNA_binding; SSF47729 IHF_like_DNA_bnd

EC number: NA

Molecular weight: Translated: 11307; Mature: 11176

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTKAEMVERLFDEVGLNKREAKEFVDAFFDLLRDALEQGKEIKLSGFGNFELRCKNQR
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCC
PGRNPKTGEEIPISARTVVTFRSGQKLKERVDAYVGSRQ
CCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ALTKAEMVERLFDEVGLNKREAKEFVDAFFDLLRDALEQGKEIKLSGFGNFELRCKNQR
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCC
PGRNPKTGEEIPISARTVVTFRSGQKLKERVDAYVGSRQ
CCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA