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The map label for this gene is trpD [H]

Identifier: 28198779

GI number: 28198779

Start: 1087303

End: 1087923

Strand: Reverse

Name: trpD [H]

Synonym: PD0876

Alternate gene names: 28198779

Gene position: 1087923-1087303 (Counterclockwise)

Preceding gene: 28198781

Following gene: 28198778

Centisome position: 43.17

GC content: 38.16

Gene sequence:

>621_bases
ATGCCATATCGAGTCATCGTCGTAGATGCTTATGACAGTTTTGTTCATATCTTGGTCTCATATTTTGAGCAGCTCGGTTG
CAAAGTCACTGTATTGAGAAAAGATGATCCAGGATTGTTAGCACTTATTGACCCACTTTATAGCGACATAATCGTACTAG
GACCAGGACCAGGACATCCATCACAATCAGGTTACGATATCATCCTAAATAAAAATTCAGGACGATTACCTGTGCTTGGA
GTATGTTTGGGCCATCAAGCGATTGGCCTATATTATGGGTGCATTATAGAATATGCTAAAAATCTGATGCACGGCAAAAC
AAGTCTGATCAAACACGATGGTCAAGGTTGTTATGTCTCCTTAAATAGTAGAACGTTGAAAGTCATGCGTTATCACTCAA
TCATTGTCGCAAACAAAGATATTCCAAGTCATATGGCCGTGACGTCTTACTCAATAGACGATAATTACATTATGGGGTTA
CGACATCAGAGTTTGCCAATCGAATCAGTACAATTTCATCCGGAAAGCATTGCTACCGAATGTGGCTTGGATTTGATAAA
GAACTTTATTACTACTTATACTTTTAATAAGAAAGGATGCAAATATGAAGAACTACACTAA

Upstream 100 bases:

>100_bases
CTGCAGGGATTGTTTCCGACTCTCAAGAACAGTCTGAGTACTTAGAAACACTTCACAAAATGGGATCTATGTTTAAAGCA
ATTACTGGGGAAGAAATTTC

Downstream 100 bases:

>100_bases
TCGTGAAAAATTGAACGCATTTCAAAAGCGTTATGACCCTATTACTACAGCTTATCGTGACCTAACGCTGACAGAAAAAA
CTCTTCAAAAGTGGAAAGAA

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MPYRVIVVDAYDSFVHILVSYFEQLGCKVTVLRKDDPGLLALIDPLYSDIIVLGPGPGHPSQSGYDIILNKNSGRLPVLG
VCLGHQAIGLYYGCIIEYAKNLMHGKTSLIKHDGQGCYVSLNSRTLKVMRYHSIIVANKDIPSHMAVTSYSIDDNYIMGL
RHQSLPIESVQFHPESIATECGLDLIKNFITTYTFNKKGCKYEELH

Sequences:

>Translated_206_residues
MPYRVIVVDAYDSFVHILVSYFEQLGCKVTVLRKDDPGLLALIDPLYSDIIVLGPGPGHPSQSGYDIILNKNSGRLPVLG
VCLGHQAIGLYYGCIIEYAKNLMHGKTSLIKHDGQGCYVSLNSRTLKVMRYHSIIVANKDIPSHMAVTSYSIDDNYIMGL
RHQSLPIESVQFHPESIATECGLDLIKNFITTYTFNKKGCKYEELH
>Mature_205_residues
PYRVIVVDAYDSFVHILVSYFEQLGCKVTVLRKDDPGLLALIDPLYSDIIVLGPGPGHPSQSGYDIILNKNSGRLPVLGV
CLGHQAIGLYYGCIIEYAKNLMHGKTSLIKHDGQGCYVSLNSRTLKVMRYHSIIVANKDIPSHMAVTSYSIDDNYIMGLR
HQSLPIESVQFHPESIATECGLDLIKNFITTYTFNKKGCKYEELH

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=187, Percent_Identity=43.3155080213904, Blast_Score=150, Evalue=4e-38,
Organism=Escherichia coli, GI1787517, Length=190, Percent_Identity=34.2105263157895, Blast_Score=115, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6322638, Length=202, Percent_Identity=38.1188118811881, Blast_Score=128, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6324361, Length=226, Percent_Identity=30.9734513274336, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 23007; Mature: 22876

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYRVIVVDAYDSFVHILVSYFEQLGCKVTVLRKDDPGLLALIDPLYSDIIVLGPGPGHP
CCEEEEEEECHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEECHHHCCEEEECCCCCCC
SQSGYDIILNKNSGRLPVLGVCLGHQAIGLYYGCIIEYAKNLMHGKTSLIKHDGQGCYVS
CCCCCEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHEEECCCEEEEE
LNSRTLKVMRYHSIIVANKDIPSHMAVTSYSIDDNYIMGLRHQSLPIESVQFHPESIATE
ECCCEEEEEEEEEEEEECCCCCCCEEEEEEECCCCEEEEEECCCCCCCCEEECCHHHHHH
CGLDLIKNFITTYTFNKKGCKYEELH
CCHHHHHHHHHHEEECCCCCCCCCCC
>Mature Secondary Structure 
PYRVIVVDAYDSFVHILVSYFEQLGCKVTVLRKDDPGLLALIDPLYSDIIVLGPGPGHP
CEEEEEEECHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEECHHHCCEEEECCCCCCC
SQSGYDIILNKNSGRLPVLGVCLGHQAIGLYYGCIIEYAKNLMHGKTSLIKHDGQGCYVS
CCCCCEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHEEECCCEEEEE
LNSRTLKVMRYHSIIVANKDIPSHMAVTSYSIDDNYIMGLRHQSLPIESVQFHPESIATE
ECCCEEEEEEEEEEEEECCCCCCCEEEEEEECCCCEEEEEECCCCCCCCEEECCHHHHHH
CGLDLIKNFITTYTFNKKGCKYEELH
CCHHHHHHHHHHEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2404959; 659439 [H]