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The map label for this gene is pepB [H]

Identifier: 27366071

GI number: 27366071

Start: 2846882

End: 2848681

Strand: Reverse

Name: pepB [H]

Synonym: VV1_2784

Alternate gene names: 27366071

Gene position: 2848681-2846882 (Counterclockwise)

Preceding gene: 27366072

Following gene: 326424074

Centisome position: 86.8

GC content: 49.78

Gene sequence:

>1800_bases
ATGACCGCGCCAAGCTGGGATCTTTCTATTGCCTATGCAGATTTAAACGATGTTCGTATCGAACAAGATATCGAACTGAT
CGAACAGTGCATCAAACTGCTCAATACACAAGCGTCACAGCGTGAAGTGGTGAGCGTGATGCAAAATGCCATCGTCACCC
GAGAAGCCGCAGGGCGTTTACTTTCGACGGTTTACACCTTTGCCAACTGTTATACCTCGGTGGATGTGACTCATCCTCAG
GCCAAAGCTTTGGTTGGACGCATGGCCAAGCTAAGTTCTGAAATGGAACAGGCATTTAGCCCATACCAACTGGCGCTAAT
GCACGCAGATGACGATTTCATCGCCGACGTTTTAGAGAGCAATAATCCCGATGTGGCTGGTCAAGTATTTTCCATTGCTC
AGCTGCGTAAGCTGGCGGATCAAAGCTTGAGTGTGTCTGAGGAACAACTACTTTCTGCGATGCAGGTGGACGGGCGCGAT
GGTTGGGGCCGTCTCTACGACAACCTGACTGGCACCTTAAAAATCACCCTAGATGCTGAAGATGGCACACAAGAAACGCT
TGGCTTTTCTCAAGCCGCCAGTTTGCTTTATGGGGCCGAGTTCTCTCGTCAAGAACCCGCGTGGCGTGGGATTCAAAACG
CAATGGCAACACATCGTGAAACCTTTGCGGCAATTTTGAATGCGCTTTCTGGCTGGCGTTTAACCGAATACCAAAAGCGC
TCGCACCAACGCAATATCCACTTCTTAGAGCCAAGCCTTTATGAGAGCCGTATTGAGGCTCAGACCTTAGAAACCATGAT
CTCTGTGGCAAAGGAAAGTCGCTCGGTTGGCCAGAAGGCGGGGAAGCTAATGGCGCGTGTGCATGGCTTAGAGGCAATGA
AGCCTTGGAATCACTTGGCCGCAATGCCAGCGTTTGATGGCGAGGCCAAAGTGTATGGCTTTGATGAAGCGATTGAACTG
ATCCGCAATGCGTTTGCACAAGTCAACCCAGAGATGGCAAGCTTTGTTGACCTCATGGTGGAAAATGGCTGGATTGATGC
TGCGCCTTCGGAAAATAAACGCCTCGGTGCGTACTGCACTAAACTAGCGGCCACCCGTACACCGCTGGTGTTTATGACTT
GGTCGGGCAGCCGTTCGGATTTGCTGACTTTGGCCCATGAACTCGGGCACGCGTTCCACAACTGGGTGATGAAAGACATG
CCCCTTTGTCAAACGCGTTACCCAATGACGCTGGCAGAAACGGCGTCTATTTTTGCGGAGAACATTGTTCAGGATTACCT
GATTGCACAAGCCGTCACCGCTGAAGAGAAACTGGAAATGTTGTGGGAAGAGCTCTCTTCTGCTTACGCGCTCACCATCA
ATATTCCTGTACGTTACGAATTTGAAAAAGCGTTCTATGAGCGTCGTGCCAGCGGTGAATTGTCGGCGGATGATATTTGC
CTGTTGATGAGTGAAACTTGGCAAGCGTGGTATGGCGATTCAATGTCAGAATCCGATCCCTATTTCTGGGCCAGCAAACT
TCATTTCTCGATTTCAGAAATCAGTTTCTACAACTACCCCTATTTGTTTGGTTACCTTTTCTCGAAAGGCATCTACGCTC
AGCGTGCGGCAAAGGGAGAGTCTTTCTATCGTGATTACGTCGCTTTGCTGCGAGATACAGGGGCGATGATGGCGGAAGAG
GTGGTCGCGCAGCATCTGCAAATGGATCTGACGCAAGCGGATTTCTGGCAACAGAGCATCGAACGTATCCGTGAAAAAGT
GGATGAATTTGAACAACTATTGGTGCAGATCGGAAAATAA

Upstream 100 bases:

>100_bases
GCAGTTTCCGACAGTCAAAATGATCGGGATGCCTCTCTCTATCAGGGAAGAACAGACGAATCATCCAGTCGATTAGTCAC
AGATTCATAAGGAACACAGA

Downstream 100 bases:

>100_bases
AATTCCGTGATCTTGTTATAACGGAAATGGTTAGGGATGTGGTAGAGTTCACTCCCTAACATACTGTTATTGTTTAAGAA
GTGTTCGGTGACGGTGATCT

Product: Oligoendopeptidase F

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 599; Mature: 598

Protein sequence:

>599_residues
MTAPSWDLSIAYADLNDVRIEQDIELIEQCIKLLNTQASQREVVSVMQNAIVTREAAGRLLSTVYTFANCYTSVDVTHPQ
AKALVGRMAKLSSEMEQAFSPYQLALMHADDDFIADVLESNNPDVAGQVFSIAQLRKLADQSLSVSEEQLLSAMQVDGRD
GWGRLYDNLTGTLKITLDAEDGTQETLGFSQAASLLYGAEFSRQEPAWRGIQNAMATHRETFAAILNALSGWRLTEYQKR
SHQRNIHFLEPSLYESRIEAQTLETMISVAKESRSVGQKAGKLMARVHGLEAMKPWNHLAAMPAFDGEAKVYGFDEAIEL
IRNAFAQVNPEMASFVDLMVENGWIDAAPSENKRLGAYCTKLAATRTPLVFMTWSGSRSDLLTLAHELGHAFHNWVMKDM
PLCQTRYPMTLAETASIFAENIVQDYLIAQAVTAEEKLEMLWEELSSAYALTINIPVRYEFEKAFYERRASGELSADDIC
LLMSETWQAWYGDSMSESDPYFWASKLHFSISEISFYNYPYLFGYLFSKGIYAQRAAKGESFYRDYVALLRDTGAMMAEE
VVAQHLQMDLTQADFWQQSIERIREKVDEFEQLLVQIGK

Sequences:

>Translated_599_residues
MTAPSWDLSIAYADLNDVRIEQDIELIEQCIKLLNTQASQREVVSVMQNAIVTREAAGRLLSTVYTFANCYTSVDVTHPQ
AKALVGRMAKLSSEMEQAFSPYQLALMHADDDFIADVLESNNPDVAGQVFSIAQLRKLADQSLSVSEEQLLSAMQVDGRD
GWGRLYDNLTGTLKITLDAEDGTQETLGFSQAASLLYGAEFSRQEPAWRGIQNAMATHRETFAAILNALSGWRLTEYQKR
SHQRNIHFLEPSLYESRIEAQTLETMISVAKESRSVGQKAGKLMARVHGLEAMKPWNHLAAMPAFDGEAKVYGFDEAIEL
IRNAFAQVNPEMASFVDLMVENGWIDAAPSENKRLGAYCTKLAATRTPLVFMTWSGSRSDLLTLAHELGHAFHNWVMKDM
PLCQTRYPMTLAETASIFAENIVQDYLIAQAVTAEEKLEMLWEELSSAYALTINIPVRYEFEKAFYERRASGELSADDIC
LLMSETWQAWYGDSMSESDPYFWASKLHFSISEISFYNYPYLFGYLFSKGIYAQRAAKGESFYRDYVALLRDTGAMMAEE
VVAQHLQMDLTQADFWQQSIERIREKVDEFEQLLVQIGK
>Mature_598_residues
TAPSWDLSIAYADLNDVRIEQDIELIEQCIKLLNTQASQREVVSVMQNAIVTREAAGRLLSTVYTFANCYTSVDVTHPQA
KALVGRMAKLSSEMEQAFSPYQLALMHADDDFIADVLESNNPDVAGQVFSIAQLRKLADQSLSVSEEQLLSAMQVDGRDG
WGRLYDNLTGTLKITLDAEDGTQETLGFSQAASLLYGAEFSRQEPAWRGIQNAMATHRETFAAILNALSGWRLTEYQKRS
HQRNIHFLEPSLYESRIEAQTLETMISVAKESRSVGQKAGKLMARVHGLEAMKPWNHLAAMPAFDGEAKVYGFDEAIELI
RNAFAQVNPEMASFVDLMVENGWIDAAPSENKRLGAYCTKLAATRTPLVFMTWSGSRSDLLTLAHELGHAFHNWVMKDMP
LCQTRYPMTLAETASIFAENIVQDYLIAQAVTAEEKLEMLWEELSSAYALTINIPVRYEFEKAFYERRASGELSADDICL
LMSETWQAWYGDSMSESDPYFWASKLHFSISEISFYNYPYLFGYLFSKGIYAQRAAKGESFYRDYVALLRDTGAMMAEEV
VAQHLQMDLTQADFWQQSIERIREKVDEFEQLLVQIGK

Specific function: Has oligopeptidase activity and degrades a variety of small bioactive peptides, including bradykinin, neurotensin, and peptide fragments of substance P and adrenocorticotropin. Also hydrolyzes the synthetic collagen-like substrate N-(3-[2- furyl]acryloyl)

COG id: COG1164

COG function: function code E; Oligoendopeptidase F

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567
- InterPro:   IPR004438
- InterPro:   IPR013647 [H]

Pfam domain/function: PF01432 Peptidase_M3; PF08439 Peptidase_M3_N [H]

EC number: NA

Molecular weight: Translated: 67677; Mature: 67546

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPSWDLSIAYADLNDVRIEQDIELIEQCIKLLNTQASQREVVSVMQNAIVTREAAGRL
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LSTVYTFANCYTSVDVTHPQAKALVGRMAKLSSEMEQAFSPYQLALMHADDDFIADVLES
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHC
NNPDVAGQVFSIAQLRKLADQSLSVSEEQLLSAMQVDGRDGWGRLYDNLTGTLKITLDAE
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHCCCEEEEEEEECC
DGTQETLGFSQAASLLYGAEFSRQEPAWRGIQNAMATHRETFAAILNALSGWRLTEYQKR
CCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
SHQRNIHFLEPSLYESRIEAQTLETMISVAKESRSVGQKAGKLMARVHGLEAMKPWNHLA
HHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AMPAFDGEAKVYGFDEAIELIRNAFAQVNPEMASFVDLMVENGWIDAAPSENKRLGAYCT
CCCCCCCCCEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
KLAATRTPLVFMTWSGSRSDLLTLAHELGHAFHNWVMKDMPLCQTRYPMTLAETASIFAE
HHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
NIVQDYLIAQAVTAEEKLEMLWEELSSAYALTINIPVRYEFEKAFYERRASGELSADDIC
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECEEEHHHHHHHHHHCCCCCCCCCEE
LLMSETWQAWYGDSMSESDPYFWASKLHFSISEISFYNYPYLFGYLFSKGIYAQRAAKGE
EEHHHHHHHHCCCCCCCCCCCEEHHHHEEEHHHHEECCCHHHHHHHHHCCHHHHHHHCCH
SFYRDYVALLRDTGAMMAEEVVAQHLQMDLTQADFWQQSIERIREKVDEFEQLLVQIGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TAPSWDLSIAYADLNDVRIEQDIELIEQCIKLLNTQASQREVVSVMQNAIVTREAAGRL
CCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LSTVYTFANCYTSVDVTHPQAKALVGRMAKLSSEMEQAFSPYQLALMHADDDFIADVLES
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHC
NNPDVAGQVFSIAQLRKLADQSLSVSEEQLLSAMQVDGRDGWGRLYDNLTGTLKITLDAE
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHCCCEEEEEEEECC
DGTQETLGFSQAASLLYGAEFSRQEPAWRGIQNAMATHRETFAAILNALSGWRLTEYQKR
CCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
SHQRNIHFLEPSLYESRIEAQTLETMISVAKESRSVGQKAGKLMARVHGLEAMKPWNHLA
HHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AMPAFDGEAKVYGFDEAIELIRNAFAQVNPEMASFVDLMVENGWIDAAPSENKRLGAYCT
CCCCCCCCCEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
KLAATRTPLVFMTWSGSRSDLLTLAHELGHAFHNWVMKDMPLCQTRYPMTLAETASIFAE
HHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
NIVQDYLIAQAVTAEEKLEMLWEELSSAYALTINIPVRYEFEKAFYERRASGELSADDIC
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECEEEHHHHHHHHHHCCCCCCCCCEE
LLMSETWQAWYGDSMSESDPYFWASKLHFSISEISFYNYPYLFGYLFSKGIYAQRAAKGE
EEHHHHHHHHCCCCCCCCCCCEEHHHHEEEHHHHEECCCHHHHHHHHHCCHHHHHHHCCH
SFYRDYVALLRDTGAMMAEEVVAQHLQMDLTQADFWQQSIERIREKVDEFEQLLVQIGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8757883; 12354221 [H]