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The map label for this gene is fabH [H]

Identifier: 27365197

GI number: 27365197

Start: 1843741

End: 1844730

Strand: Reverse

Name: fabH [H]

Synonym: VV1_1846

Alternate gene names: 27365197

Gene position: 1844730-1843741 (Counterclockwise)

Preceding gene: 27365198

Following gene: 27365196

Centisome position: 56.21

GC content: 45.56

Gene sequence:

>990_bases
ATGGGCTTTAATATCCTTTCCAGTGGAAGCTATCTGCCAGTCAATCAGTGGTCAGATCGGGAGATGGATCGCTTCCTAAA
ATTACCCTCAGGAACTTGTCGAAACAAATTCGACGTTGAGTATCGTCATGTAGCCGACACGAAAGAAACCGCTGTATATA
TGGCAATGCAAGCGATAACGCAATGTCTCGCTAACACACATTCGCTAAGTTCTGTTAACCTCCTTATTTATGCCAGTGGC
ACACATCATCAGTCTTTACCTTATGATGCATCGGCAGTCTTAGCGGCATTAGACGCCCCGACATCGCTAGAAAGTTTTGA
TTTAAACAGTACGTGTTTGTCTTTTCTCTCCGCTCTCAATCTTGCTCAGAACCTTTTTTTAGCAAAACGCTACCAACGTA
TTCTTATTGTCACCAGTGAGCTCGCTACGGGCATCACATTGAATCGCAGCTTCACACTCAAACCTGAAGTTGCAACCTTA
TTCGCCGACGGTGCAGCAGCGTTTTTACTAGAGCAAACAGAGAATGAAGGGCTGCTCACGAGCCACTTTGAAACGCATCA
CGCTGGGTATTCATTCTGTCAAATAAAGGGGGGAGGCAGTCATATCAACCCGCATACTTCAGAGCATCAAGCCTATTTGA
AAAACTGCCAATTTGAAATGGAAGGCAAAGCACTGTTTAAACATGTGCGCAAAACTTTGCCTGCGTTTCTTGAAAAAGGC
TTTTGCTCCTCTCCAGTTACCCTTCGCGATATTGACTACTTTCTTCCACACCAAGCGAGTGCTCACGGTTTAAAGAAATT
ACCCTCACTCGTTGGTTTACCGAAAGAGAAAATCGTTAATCACTTTTCCACCTTGGGTAACCAAGTCGCTGCGTCATTGC
CGATAAACTTGCACTGGCTACGCAACCAACCAGGCACACAAGGGAAACATGTTTTATTGGCGGGCACTGCTGCTGGGCTC
TCGTTGGGGATGGGAGTCCTTAAACTATGA

Upstream 100 bases:

>100_bases
ATTCGCATTCTCTCACTTACCTTTTTCACCCTCTTGATATAGATCCAATATGCAACTTGAATTATTTTGAACGGCGTTTT
TAATGACTTTGTAGAAAATA

Downstream 100 bases:

>100_bases
AAATATTAGTCACAGGTGGCAGTGGTATGCTGGGTAGTGCGATTCTACGGATGTTTCACCAGCAACATGAACTGCACTTT
ACTGCGCGAAATACTGTCAT

Product: 3-oxoacyl-synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MGFNILSSGSYLPVNQWSDREMDRFLKLPSGTCRNKFDVEYRHVADTKETAVYMAMQAITQCLANTHSLSSVNLLIYASG
THHQSLPYDASAVLAALDAPTSLESFDLNSTCLSFLSALNLAQNLFLAKRYQRILIVTSELATGITLNRSFTLKPEVATL
FADGAAAFLLEQTENEGLLTSHFETHHAGYSFCQIKGGGSHINPHTSEHQAYLKNCQFEMEGKALFKHVRKTLPAFLEKG
FCSSPVTLRDIDYFLPHQASAHGLKKLPSLVGLPKEKIVNHFSTLGNQVAASLPINLHWLRNQPGTQGKHVLLAGTAAGL
SLGMGVLKL

Sequences:

>Translated_329_residues
MGFNILSSGSYLPVNQWSDREMDRFLKLPSGTCRNKFDVEYRHVADTKETAVYMAMQAITQCLANTHSLSSVNLLIYASG
THHQSLPYDASAVLAALDAPTSLESFDLNSTCLSFLSALNLAQNLFLAKRYQRILIVTSELATGITLNRSFTLKPEVATL
FADGAAAFLLEQTENEGLLTSHFETHHAGYSFCQIKGGGSHINPHTSEHQAYLKNCQFEMEGKALFKHVRKTLPAFLEKG
FCSSPVTLRDIDYFLPHQASAHGLKKLPSLVGLPKEKIVNHFSTLGNQVAASLPINLHWLRNQPGTQGKHVLLAGTAAGL
SLGMGVLKL
>Mature_328_residues
GFNILSSGSYLPVNQWSDREMDRFLKLPSGTCRNKFDVEYRHVADTKETAVYMAMQAITQCLANTHSLSSVNLLIYASGT
HHQSLPYDASAVLAALDAPTSLESFDLNSTCLSFLSALNLAQNLFLAKRYQRILIVTSELATGITLNRSFTLKPEVATLF
ADGAAAFLLEQTENEGLLTSHFETHHAGYSFCQIKGGGSHINPHTSEHQAYLKNCQFEMEGKALFKHVRKTLPAFLEKGF
CSSPVTLRDIDYFLPHQASAHGLKKLPSLVGLPKEKIVNHFSTLGNQVAASLPINLHWLRNQPGTQGKHVLLAGTAAGLS
LGMGVLKL

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=332, Percent_Identity=22.5903614457831, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 36044; Mature: 35912

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFNILSSGSYLPVNQWSDREMDRFLKLPSGTCRNKFDVEYRHVADTKETAVYMAMQAIT
CCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEHHHCCCHHHHHHHHHHHHH
QCLANTHSLSSVNLLIYASGTHHQSLPYDASAVLAALDAPTSLESFDLNSTCLSFLSALN
HHHHCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
LAQNLFLAKRYQRILIVTSELATGITLNRSFTLKPEVATLFADGAAAFLLEQTENEGLLT
HHHHHHHHHHHHEEEEEEEHHHCCEEECCEEEECCHHHEEEECCCEEEEEEECCCCCCEE
SHFETHHAGYSFCQIKGGGSHINPHTSEHQAYLKNCQFEMEGKALFKHVRKTLPAFLEKG
ECCHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHCC
FCSSPVTLRDIDYFLPHQASAHGLKKLPSLVGLPKEKIVNHFSTLGNQVAASLPINLHWL
CCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEE
RNQPGTQGKHVLLAGTAAGLSLGMGVLKL
CCCCCCCCCEEEEEECHHHHHHHHHHHCC
>Mature Secondary Structure 
GFNILSSGSYLPVNQWSDREMDRFLKLPSGTCRNKFDVEYRHVADTKETAVYMAMQAIT
CCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEHHHCCCHHHHHHHHHHHHH
QCLANTHSLSSVNLLIYASGTHHQSLPYDASAVLAALDAPTSLESFDLNSTCLSFLSALN
HHHHCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
LAQNLFLAKRYQRILIVTSELATGITLNRSFTLKPEVATLFADGAAAFLLEQTENEGLLT
HHHHHHHHHHHHEEEEEEEHHHCCEEECCEEEECCHHHEEEECCCEEEEEEECCCCCCEE
SHFETHHAGYSFCQIKGGGSHINPHTSEHQAYLKNCQFEMEGKALFKHVRKTLPAFLEKG
ECCHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHCC
FCSSPVTLRDIDYFLPHQASAHGLKKLPSLVGLPKEKIVNHFSTLGNQVAASLPINLHWL
CCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEE
RNQPGTQGKHVLLAGTAAGLSLGMGVLKL
CCCCCCCCCEEEEEECHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]