Click here to switch to the map view.

The map label for this gene is can [H]

Identifier: 27365000

GI number: 27365000

Start: 1605648

End: 1606316

Strand: Reverse

Name: can [H]

Synonym: VV1_1637

Alternate gene names: 27365000

Gene position: 1606316-1605648 (Counterclockwise)

Preceding gene: 27365004

Following gene: 326423860

Centisome position: 48.95

GC content: 46.34

Gene sequence:

>669_bases
ATGCCGGAAATCAAGCAACTATTTGAAAATAACTCGAAATGGTCCGAAGAGATCAAATCGCATCAACCGGAGTATTTCTC
CAAATTAGAAGAAGGGCAAAATCCCGGCTTTCTTTGGATTGGTTGTTCCGACAGTCGCGTTCCTGCAGAACGCTTGACAG
GACTTTACTCGGGTGAATTATTTGTTCATCGTAATGTAGCCAACCAAGTGATCCATACCGATTTAAATTGCCTCTCGGTT
GTGCAATACGCTGTTGACGTGTTGAAAGTCAAACACATCATCATCTGTGGCCATTACGGTTGTGGGGGGGTAAACGCTGC
GATTGAAAATCCTCGCCTTGGTTTGATCAATAACTGGCTACTGCACATTCGCGATCTCTACCTCAAGCATCGTAACTGGC
TGGGTGAGCTCCCGAAGGAGAAATGGGGCGACAAACTGTGTGAAATCAATGTCGCAGAACAAGTCTACAACTTGGGCAAT
TCTACGATTATGGAAAGCGCTTGGGAGCGTGGACAAGATGTGGAAATTCACGGCGTTGTCTATGGCATTGGTGATGGCCT
TCTGCAAGATATTGGCGTGCGTTGCTACAGCCGAGAGTCACTCGAAGTCAACTATCAGGCTGCGATGGCAAAAATCCTCA
ATAGCGATGTGATGAAGTTTCACGAATAG

Upstream 100 bases:

>100_bases
TAACTAGTCAGATGAGTGCTTTTCTGCCAATTTATTTCGGGTGGTAAATTGTAACATTGTGTATAGTGATGCAAGAATTT
TTAGGGAAGTAAGACGCAAC

Downstream 100 bases:

>100_bases
CGCCATCGTTAGACCGCCGACACAATCCGTGTTCTAGAGATAACATGGCAAATGGCCCGCTGTATCAGCGGGCCATTATT
TATCTCAACCTTTGCCCACT

Product: carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MPEIKQLFENNSKWSEEIKSHQPEYFSKLEEGQNPGFLWIGCSDSRVPAERLTGLYSGELFVHRNVANQVIHTDLNCLSV
VQYAVDVLKVKHIIICGHYGCGGVNAAIENPRLGLINNWLLHIRDLYLKHRNWLGELPKEKWGDKLCEINVAEQVYNLGN
STIMESAWERGQDVEIHGVVYGIGDGLLQDIGVRCYSRESLEVNYQAAMAKILNSDVMKFHE

Sequences:

>Translated_222_residues
MPEIKQLFENNSKWSEEIKSHQPEYFSKLEEGQNPGFLWIGCSDSRVPAERLTGLYSGELFVHRNVANQVIHTDLNCLSV
VQYAVDVLKVKHIIICGHYGCGGVNAAIENPRLGLINNWLLHIRDLYLKHRNWLGELPKEKWGDKLCEINVAEQVYNLGN
STIMESAWERGQDVEIHGVVYGIGDGLLQDIGVRCYSRESLEVNYQAAMAKILNSDVMKFHE
>Mature_221_residues
PEIKQLFENNSKWSEEIKSHQPEYFSKLEEGQNPGFLWIGCSDSRVPAERLTGLYSGELFVHRNVANQVIHTDLNCLSVV
QYAVDVLKVKHIIICGHYGCGGVNAAIENPRLGLINNWLLHIRDLYLKHRNWLGELPKEKWGDKLCEINVAEQVYNLGNS
TIMESAWERGQDVEIHGVVYGIGDGLLQDIGVRCYSRESLEVNYQAAMAKILNSDVMKFHE

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=212, Percent_Identity=66.9811320754717, Blast_Score=300, Evalue=6e-83,
Organism=Escherichia coli, GI1786534, Length=190, Percent_Identity=30, Blast_Score=75, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6324292, Length=199, Percent_Identity=30.6532663316583, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 25269; Mature: 25138

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEIKQLFENNSKWSEEIKSHQPEYFSKLEEGQNPGFLWIGCSDSRVPAERLTGLYSGEL
CCHHHHHHCCCCHHHHHHHCCCCHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHCCCE
FVHRNVANQVIHTDLNCLSVVQYAVDVLKVKHIIICGHYGCGGVNAAIENPRLGLINNWL
EEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCHHHHHH
LHIRDLYLKHRNWLGELPKEKWGDKLCEINVAEQVYNLGNSTIMESAWERGQDVEIHGVV
HHHHHHHHHHHHHHHCCCHHHHCCHHEEEHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEE
YGIGDGLLQDIGVRCYSRESLEVNYQAAMAKILNSDVMKFHE
EECCHHHHHHHCCHHCCCCCCEEHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PEIKQLFENNSKWSEEIKSHQPEYFSKLEEGQNPGFLWIGCSDSRVPAERLTGLYSGEL
CHHHHHHCCCCHHHHHHHCCCCHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHCCCE
FVHRNVANQVIHTDLNCLSVVQYAVDVLKVKHIIICGHYGCGGVNAAIENPRLGLINNWL
EEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCHHHHHH
LHIRDLYLKHRNWLGELPKEKWGDKLCEINVAEQVYNLGNSTIMESAWERGQDVEIHGVV
HHHHHHHHHHHHHHHCCCHHHHCCHHEEEHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEE
YGIGDGLLQDIGVRCYSRESLEVNYQAAMAKILNSDVMKFHE
EECCHHHHHHHCCHHCCCCCCEEHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]