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The map label for this gene is pilE [H]

Identifier: 27364990

GI number: 27364990

Start: 1594174

End: 1594620

Strand: Reverse

Name: pilE [H]

Synonym: VV1_1626

Alternate gene names: 27364990

Gene position: 1594620-1594174 (Counterclockwise)

Preceding gene: 27364991

Following gene: 27364989

Centisome position: 48.59

GC content: 40.27

Gene sequence:

>447_bases
ATGATGAAGAAATTGAACAAAACCAAGAAACAACAAGGTTTTACCTTGATTGAGTTAATGATAGTGGTGGCGATTATTGG
TGTATTGGCTGCTGTTGCTATTCCAGCGTATCAGAATTACGTTCAAAAAACTGAAGTTGCATCGGCATCAGCAACAGTAA
GAGGATTACTAACAAACATTGATATGTATCAGCAAGAAAATGGCGGAACTTTTCCAAACAATGCCAATTTAGTTGGCGGC
ACTTCAACAATGAATGCTCTTGGTACCATAACACTGTTGCCAGTTGGTACTAGTGGTGGAACAGCAACTTTTGCCTTTAC
CGAAGGTACACTCAAAGGCAAAACTGCCTCAGTCCAGTACTCGAAAAACAACACTACTGGTTGGAGCTGTGCGACAAAAA
ATGTACCTGCAGATTCTCGTCCAAATAGTTGTACTGCCACTTATTAA

Upstream 100 bases:

>100_bases
AATCACTCGAGTGATGCTCTTGGTGTGATTTCCACTCGTCTACTCCTTGCATAATCTAGCCGCAAGCTCGCGGAGCGAAT
TTGATAGATTAAAGGAAATC

Downstream 100 bases:

>100_bases
TGATGTCGAATCTCTCCACTATTCTGCGTCAGGCCAATCAGCTTAGCCTAACGCAAGAACAAGCGTGTCGAGAGACAATA
CAAGCTTCTGGTGTGACAGC

Product: type IV pilin PilA

Products: NA

Alternate protein names: Pilin [H]

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MMKKLNKTKKQQGFTLIELMIVVAIIGVLAAVAIPAYQNYVQKTEVASASATVRGLLTNIDMYQQENGGTFPNNANLVGG
TSTMNALGTITLLPVGTSGGTATFAFTEGTLKGKTASVQYSKNNTTGWSCATKNVPADSRPNSCTATY

Sequences:

>Translated_148_residues
MMKKLNKTKKQQGFTLIELMIVVAIIGVLAAVAIPAYQNYVQKTEVASASATVRGLLTNIDMYQQENGGTFPNNANLVGG
TSTMNALGTITLLPVGTSGGTATFAFTEGTLKGKTASVQYSKNNTTGWSCATKNVPADSRPNSCTATY
>Mature_148_residues
MMKKLNKTKKQQGFTLIELMIVVAIIGVLAAVAIPAYQNYVQKTEVASASATVRGLLTNIDMYQQENGGTFPNNANLVGG
TSTMNALGTITLLPVGTSGGTATFAFTEGTLKGKTASVQYSKNNTTGWSCATKNVPADSRPNSCTATY

Specific function: This protein is the predominant Neisseria surface antigen, which allows adhesion of the bacterium to various host cells [H]

COG id: COG4969

COG function: function code NU; Tfp pilus assembly protein, major pilin PilA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-Me-Phe pilin family [H]

Homologues:

Organism=Escherichia coli, GI1786297, Length=61, Percent_Identity=45.9016393442623, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001082
- InterPro:   IPR012902
- InterPro:   IPR001120 [H]

Pfam domain/function: PF07963 N_methyl; PF00114 Pilin [H]

EC number: NA

Molecular weight: Translated: 15534; Mature: 15534

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS00409 PROKAR_NTER_METHYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKKLNKTKKQQGFTLIELMIVVAIIGVLAAVAIPAYQNYVQKTEVASASATVRGLLTNI
CCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DMYQQENGGTFPNNANLVGGTSTMNALGTITLLPVGTSGGTATFAFTEGTLKGKTASVQY
HHEECCCCCCCCCCCEEECCCCHHHCCEEEEEEEECCCCCEEEEEEECCCCCCCEEEEEE
SKNNTTGWSCATKNVPADSRPNSCTATY
CCCCCCCCEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MMKKLNKTKKQQGFTLIELMIVVAIIGVLAAVAIPAYQNYVQKTEVASASATVRGLLTNI
CCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DMYQQENGGTFPNNANLVGGTSTMNALGTITLLPVGTSGGTATFAFTEGTLKGKTASVQY
HHEECCCCCCCCCCCEEECCCCHHHCCEEEEEEEECCCCCEEEEEEECCCCCCCEEEEEE
SKNNTTGWSCATKNVPADSRPNSCTATY
CCCCCCCCEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919; 9515697 [H]