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The map label for this gene is sdcS [H]

Identifier: 27364683

GI number: 27364683

Start: 1267379

End: 1268794

Strand: Reverse

Name: sdcS [H]

Synonym: VV1_1283

Alternate gene names: 27364683

Gene position: 1268794-1267379 (Counterclockwise)

Preceding gene: 27364684

Following gene: 27364682

Centisome position: 38.66

GC content: 49.79

Gene sequence:

>1416_bases
ATGCAGAAATTGAACATGACTGTGGTATGGAAGCTGCTGGTTTGTTTTGCGCTCCCTATCGGCATTTTGTTAATGCCCAT
CGATGCGATTCCTATCGATGATTTGACGCTCATTCAACATCGACTACTGGCCATCTTTCTACTTGCAGCCTTACTTTGGG
TTTTAGAGCCCGTGCCCGTTTTTGCCACTTCAATTCTGATCATCGCTCTCGAGCTGATCATGATTTCCGATAAAGGATTA
CACCTGTTCCGTACCCCGCCCGCCGGACACGATCTCGGTGAGTTGATTGGTTATACCGACATTTTTTCTGCGTTTTCCTC
GCCAATCATCATCCTTTTCATGGGCGGATTTGCACTCGCCATTGCCGCATCAAAATACGAGTTAGATAACAACCTCGCTC
GGGTACTGCTCAAGCCTTTTGGCCAGCAACCCAAATTTATTATGTTGGGATTGATGCTGATTACCGCCGTGTTTTCGATG
TTTATGTCCAATACCGCGACTACGGTCATGATGCTGGCGTTATTGGGGCCCATCGTTGCCTCGGCACCGAAAGGCGATTT
GGGCATTAAAGCGCTAGTATTGTGCATCCCAATTGCGGCGAACACGGGTGGTATTGCGACCCCGATTGGTACCCCGCCCA
ACGCCATTGCGTTGCAATATTTAACTGGAGAAAACAGCATCGACTTTCTCAGCTGGATGGCAATGGGTTTACCCTTTGTT
CTTGTTCAGTTGACCATTGCTTGGCTTTTATTGCAGAAACTCTTTCCTTCTAGCGAAGCGAAAATGACGCTGAAATTAGA
CGGCAAGTTCAAGAAAAGCTGGCGTGCCGTGGTGGTGTATATCACCTTTGCCGCCACGATTTTGCTATGGATGACCACGC
AATTGCACGGCATGAATACCTATGTAGTGGCCATCATTCCGCTGGCAGTGTTTACATTGACGGGCATTATGGGCAAAGAA
GAACTCAAGCTGATCAACTGGGACGTACTTTGGCTGGTCGCGGGGGGGATTGCCATTGGTATCGGCTTGGAAAAAACCGG
GCTGGCGAAAGCCTTAGCGCATGCCATCAATTATGAAGCTTTGTCGCCTTTTGCCATCATCGTATCGCTCTCCTTAGTCT
GCTGGCTTATGGCGAACTTTATGTCCAATACCGCGACCGCCAACTTGTTGATGCCAATCGCGGCCGCCATCGGTACCTCA
ATGAGCAGTTTAGAAGCCGTCGGAGGCTTACAAGGCTTGCTGGTGGTGGTGGCATTCTCAGCCTCGCTCGGGATGATTCT
TCCTGTATCAACGCCTCCCAACTCGCTCGCCTACTCTACCGGCCTAATCGAGAGCAAAGACATGGCCAAAGTCGGCTTGC
TGATCGGTGTGATTGGCTTAGCCATCGTCTATGGGGCCGTTTTGATTCTCGCTTAA

Upstream 100 bases:

>100_bases
TAAAAAATCAACGGAATTCAGAAACTTCAACCCGCCTCTAAGATGTTCTTTGCACAATGAATTAACCTAAGTTTTCACGT
GAAATCTTGAGGTGTGATGA

Downstream 100 bases:

>100_bases
TGAGAGAGGATAATGAGAAAGCACGACCACAAGGCGGAGAAAGTCACGTCTGTGCTTTGCCAAGATGATAACTTGAGGCA
TATTGTCGATCTCTTCAATT

Product: transporter

Products: NA

Alternate protein names: Na(+)/dicarboxylate symporter [H]

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MQKLNMTVVWKLLVCFALPIGILLMPIDAIPIDDLTLIQHRLLAIFLLAALLWVLEPVPVFATSILIIALELIMISDKGL
HLFRTPPAGHDLGELIGYTDIFSAFSSPIIILFMGGFALAIAASKYELDNNLARVLLKPFGQQPKFIMLGLMLITAVFSM
FMSNTATTVMMLALLGPIVASAPKGDLGIKALVLCIPIAANTGGIATPIGTPPNAIALQYLTGENSIDFLSWMAMGLPFV
LVQLTIAWLLLQKLFPSSEAKMTLKLDGKFKKSWRAVVVYITFAATILLWMTTQLHGMNTYVVAIIPLAVFTLTGIMGKE
ELKLINWDVLWLVAGGIAIGIGLEKTGLAKALAHAINYEALSPFAIIVSLSLVCWLMANFMSNTATANLLMPIAAAIGTS
MSSLEAVGGLQGLLVVVAFSASLGMILPVSTPPNSLAYSTGLIESKDMAKVGLLIGVIGLAIVYGAVLILA

Sequences:

>Translated_471_residues
MQKLNMTVVWKLLVCFALPIGILLMPIDAIPIDDLTLIQHRLLAIFLLAALLWVLEPVPVFATSILIIALELIMISDKGL
HLFRTPPAGHDLGELIGYTDIFSAFSSPIIILFMGGFALAIAASKYELDNNLARVLLKPFGQQPKFIMLGLMLITAVFSM
FMSNTATTVMMLALLGPIVASAPKGDLGIKALVLCIPIAANTGGIATPIGTPPNAIALQYLTGENSIDFLSWMAMGLPFV
LVQLTIAWLLLQKLFPSSEAKMTLKLDGKFKKSWRAVVVYITFAATILLWMTTQLHGMNTYVVAIIPLAVFTLTGIMGKE
ELKLINWDVLWLVAGGIAIGIGLEKTGLAKALAHAINYEALSPFAIIVSLSLVCWLMANFMSNTATANLLMPIAAAIGTS
MSSLEAVGGLQGLLVVVAFSASLGMILPVSTPPNSLAYSTGLIESKDMAKVGLLIGVIGLAIVYGAVLILA
>Mature_471_residues
MQKLNMTVVWKLLVCFALPIGILLMPIDAIPIDDLTLIQHRLLAIFLLAALLWVLEPVPVFATSILIIALELIMISDKGL
HLFRTPPAGHDLGELIGYTDIFSAFSSPIIILFMGGFALAIAASKYELDNNLARVLLKPFGQQPKFIMLGLMLITAVFSM
FMSNTATTVMMLALLGPIVASAPKGDLGIKALVLCIPIAANTGGIATPIGTPPNAIALQYLTGENSIDFLSWMAMGLPFV
LVQLTIAWLLLQKLFPSSEAKMTLKLDGKFKKSWRAVVVYITFAATILLWMTTQLHGMNTYVVAIIPLAVFTLTGIMGKE
ELKLINWDVLWLVAGGIAIGIGLEKTGLAKALAHAINYEALSPFAIIVSLSLVCWLMANFMSNTATANLLMPIAAAIGTS
MSSLEAVGGLQGLLVVVAFSASLGMILPVSTPPNSLAYSTGLIESKDMAKVGLLIGVIGLAIVYGAVLILA

Specific function: Mediates the transport of dicarboxylates across the cytoplasmic membrane via a Na(+)-electrochemical gradient [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=534, Percent_Identity=26.7790262172285, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI225637549, Length=566, Percent_Identity=24.0282685512367, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI4506979, Length=472, Percent_Identity=24.7881355932203, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI225637552, Length=472, Percent_Identity=24.7881355932203, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI219802232, Length=462, Percent_Identity=25.7575757575758, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI19923838, Length=339, Percent_Identity=25.3687315634218, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI301069349, Length=298, Percent_Identity=26.1744966442953, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI31795546, Length=340, Percent_Identity=24.1176470588235, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI31377715, Length=143, Percent_Identity=30.0699300699301, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI301069346, Length=143, Percent_Identity=30.0699300699301, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI58761541, Length=143, Percent_Identity=30.0699300699301, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI301069353, Length=143, Percent_Identity=30.0699300699301, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32565804, Length=421, Percent_Identity=27.790973871734, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71988385, Length=421, Percent_Identity=28.0285035629454, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71989118, Length=450, Percent_Identity=24.6666666666667, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI32564681, Length=509, Percent_Identity=22.3968565815324, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17551790, Length=532, Percent_Identity=23.1203007518797, Blast_Score=85, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6324340, Length=437, Percent_Identity=30.2059496567506, Blast_Score=150, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6322263, Length=408, Percent_Identity=28.6764705882353, Blast_Score=130, Evalue=7e-31,
Organism=Saccharomyces cerevisiae, GI6319885, Length=419, Percent_Identity=29.1169451073986, Blast_Score=127, Evalue=5e-30,
Organism=Drosophila melanogaster, GI281366409, Length=539, Percent_Identity=23.747680890538, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17737623, Length=539, Percent_Identity=23.747680890538, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24666468, Length=539, Percent_Identity=23.747680890538, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI45551633, Length=539, Percent_Identity=24.30426716141, Blast_Score=90, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 50219; Mature: 50219

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKLNMTVVWKLLVCFALPIGILLMPIDAIPIDDLTLIQHRLLAIFLLAALLWVLEPVPV
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHH
FATSILIIALELIMISDKGLHLFRTPPAGHDLGELIGYTDIFSAFSSPIIILFMGGFALA
HHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHH
IAASKYELDNNLARVLLKPFGQQPKFIMLGLMLITAVFSMFMSNTATTVMMLALLGPIVA
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
SAPKGDLGIKALVLCIPIAANTGGIATPIGTPPNAIALQYLTGENSIDFLSWMAMGLPFV
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHH
LVQLTIAWLLLQKLFPSSEAKMTLKLDGKFKKSWRAVVVYITFAATILLWMTTQLHGMNT
HHHHHHHHHHHHHHCCCCCCEEEEEECCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCH
YVVAIIPLAVFTLTGIMGKEELKLINWDVLWLVAGGIAIGIGLEKTGLAKALAHAINYEA
HHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHCCHHEECCCCHHHHHHHHHHHHCCCC
LSPFAIIVSLSLVCWLMANFMSNTATANLLMPIAAAIGTSMSSLEAVGGLQGLLVVVAFS
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHH
ASLGMILPVSTPPNSLAYSTGLIESKDMAKVGLLIGVIGLAIVYGAVLILA
CCCCEEEECCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQKLNMTVVWKLLVCFALPIGILLMPIDAIPIDDLTLIQHRLLAIFLLAALLWVLEPVPV
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHH
FATSILIIALELIMISDKGLHLFRTPPAGHDLGELIGYTDIFSAFSSPIIILFMGGFALA
HHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHH
IAASKYELDNNLARVLLKPFGQQPKFIMLGLMLITAVFSMFMSNTATTVMMLALLGPIVA
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
SAPKGDLGIKALVLCIPIAANTGGIATPIGTPPNAIALQYLTGENSIDFLSWMAMGLPFV
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHH
LVQLTIAWLLLQKLFPSSEAKMTLKLDGKFKKSWRAVVVYITFAATILLWMTTQLHGMNT
HHHHHHHHHHHHHHCCCCCCEEEEEECCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCH
YVVAIIPLAVFTLTGIMGKEELKLINWDVLWLVAGGIAIGIGLEKTGLAKALAHAINYEA
HHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHCCHHEECCCCHHHHHHHHHHHHCCCC
LSPFAIIVSLSLVCWLMANFMSNTATANLLMPIAAAIGTSMSSLEAVGGLQGLLVVVAFS
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHH
ASLGMILPVSTPPNSLAYSTGLIESKDMAKVGLLIGVIGLAIVYGAVLILA
CCCCEEEECCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA