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The map label for this gene is sodA [H]

Identifier: 27364653

GI number: 27364653

Start: 1237272

End: 1237880

Strand: Reverse

Name: sodA [H]

Synonym: VV1_1252

Alternate gene names: 27364653

Gene position: 1237880-1237272 (Counterclockwise)

Preceding gene: 27364654

Following gene: 27364652

Centisome position: 37.72

GC content: 49.75

Gene sequence:

>609_bases
ATGTCACACACTTTCCCTGAGCTTCCCTATTCCTACGATGCATTAGAGCCATACATCGATGCAAAAACCATGGAAGTGCA
CTACAGCAAACACCATAAAACCTATTACGATAAGTTTCTCGCGGCGATTCAAGGCAGTGAGCTTGAGCATCAAACGCTCA
CTGAGATCTTCTCAAGCATCTCTCAACACAGCCCTGCAGTGCGCAATAATGGCGGTGGCTACTACAACCATATTCTCTAC
TGGCAGTGCATGTCTCCCAATGGTGGAGGGCAACCTCAAGGCGCGCTCGCCCACGCGATTCAAGAAAAGTTTGGCACTTT
TGCGGCGTTCAAAGAGGCCTTTTCCCAAGCCGCCGTCAACACCTTTGGCTCTGGCTTTGCATGGTTAGTGGTCAAAGAGG
GTGATATTCATATCACCTCCACCAGCAATCAGGATAACCCACTGATGGATATTGCCAGCGTACGTGGCGAACCGATCCTC
GCCCTCGATGTTTGGGAGCATGCGTACTACATCCGCTATCAAAATCGCCGCCCAGAATACATTGATGCTTGGTGGAATGT
GGTCGACTGGCAAGTGGTGGAGCAAAATTATGCTCAAGCAATAGGCTAA

Upstream 100 bases:

>100_bases
CTTCCACTGGTGAAAAGGCGTTAATACCCTTACAAAGATCGCAGTTGATAATGGTTATCATTAAGATTATGGTAAATCCT
TCATCACCGGAGGATTTACC

Downstream 100 bases:

>100_bases
ACATCACCGCTCACCGGAGCACCGTCGCTTATCGGGCACTTTTATACCCAAGCCTTCAAACTTGGGTATATACTGGCCCC
CTCTTTTGACCATATTCGCT

Product: Manganese superoxide dismutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MSHTFPELPYSYDALEPYIDAKTMEVHYSKHHKTYYDKFLAAIQGSELEHQTLTEIFSSISQHSPAVRNNGGGYYNHILY
WQCMSPNGGGQPQGALAHAIQEKFGTFAAFKEAFSQAAVNTFGSGFAWLVVKEGDIHITSTSNQDNPLMDIASVRGEPIL
ALDVWEHAYYIRYQNRRPEYIDAWWNVVDWQVVEQNYAQAIG

Sequences:

>Translated_202_residues
MSHTFPELPYSYDALEPYIDAKTMEVHYSKHHKTYYDKFLAAIQGSELEHQTLTEIFSSISQHSPAVRNNGGGYYNHILY
WQCMSPNGGGQPQGALAHAIQEKFGTFAAFKEAFSQAAVNTFGSGFAWLVVKEGDIHITSTSNQDNPLMDIASVRGEPIL
ALDVWEHAYYIRYQNRRPEYIDAWWNVVDWQVVEQNYAQAIG
>Mature_201_residues
SHTFPELPYSYDALEPYIDAKTMEVHYSKHHKTYYDKFLAAIQGSELEHQTLTEIFSSISQHSPAVRNNGGGYYNHILYW
QCMSPNGGGQPQGALAHAIQEKFGTFAAFKEAFSQAAVNTFGSGFAWLVVKEGDIHITSTSNQDNPLMDIASVRGEPILA
LDVWEHAYYIRYQNRRPEYIDAWWNVVDWQVVEQNYAQAIG

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems [H]

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family [H]

Homologues:

Organism=Homo sapiens, GI67782307, Length=198, Percent_Identity=42.4242424242424, Blast_Score=171, Evalue=4e-43,
Organism=Homo sapiens, GI67782305, Length=198, Percent_Identity=42.4242424242424, Blast_Score=171, Evalue=4e-43,
Organism=Homo sapiens, GI67782309, Length=198, Percent_Identity=34.3434343434343, Blast_Score=119, Evalue=3e-27,
Organism=Escherichia coli, GI1790342, Length=205, Percent_Identity=45.3658536585366, Blast_Score=191, Evalue=2e-50,
Organism=Escherichia coli, GI1787946, Length=199, Percent_Identity=46.2311557788945, Blast_Score=186, Evalue=7e-49,
Organism=Caenorhabditis elegans, GI17506561, Length=200, Percent_Identity=35.5, Blast_Score=136, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17569479, Length=201, Percent_Identity=34.3283582089552, Blast_Score=134, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6321796, Length=208, Percent_Identity=37.0192307692308, Blast_Score=137, Evalue=2e-33,
Organism=Drosophila melanogaster, GI17136812, Length=201, Percent_Identity=39.3034825870647, Blast_Score=151, Evalue=3e-37,

Paralogues:

None

Copy number: 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831 [H]

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N [H]

EC number: =1.15.1.1 [H]

Molecular weight: Translated: 22973; Mature: 22841

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHTFPELPYSYDALEPYIDAKTMEVHYSKHHKTYYDKFLAAIQGSELEHQTLTEIFSSI
CCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
SQHSPAVRNNGGGYYNHILYWQCMSPNGGGQPQGALAHAIQEKFGTFAAFKEAFSQAAVN
HHCCCCCCCCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFGSGFAWLVVKEGDIHITSTSNQDNPLMDIASVRGEPILALDVWEHAYYIRYQNRRPEY
HCCCCEEEEEEECCCEEEEECCCCCCCHHHHHHCCCCEEEEEEECCCEEEEEECCCCCCH
IDAWWNVVDWQVVEQNYAQAIG
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SHTFPELPYSYDALEPYIDAKTMEVHYSKHHKTYYDKFLAAIQGSELEHQTLTEIFSSI
CCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
SQHSPAVRNNGGGYYNHILYWQCMSPNGGGQPQGALAHAIQEKFGTFAAFKEAFSQAAVN
HHCCCCCCCCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFGSGFAWLVVKEGDIHITSTSNQDNPLMDIASVRGEPILALDVWEHAYYIRYQNRRPEY
HCCCCEEEEEEECCCEEEEECCCCCCCHHHHHHCCCCEEEEEEECCCEEEEEECCCCCCH
IDAWWNVVDWQVVEQNYAQAIG
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1624106 [H]