Click here to switch to the map view.

The map label for this gene is prmA

Identifier: 27364635

GI number: 27364635

Start: 1211994

End: 1212881

Strand: Reverse

Name: prmA

Synonym: VV1_1233

Alternate gene names: 27364635

Gene position: 1212881-1211994 (Counterclockwise)

Preceding gene: 27364636

Following gene: 326423811

Centisome position: 36.96

GC content: 50.56

Gene sequence:

>888_bases
ATGCCTTGGATTCAAATCAAACTCAATGCGACCAACGAAAACGCTGAGCTTATCGGCGATATGCTTATGGAAGAGACTGG
CGCGCTATCGGTGACTTTCCTAGATGCGCACGATACCCCTGTCTTCGAGCCACTGCCTGGTGAAACGCGTCTTTGGGGTG
ATACGGATGTCCTGGCACTGTACGACGCAGAGGCGGACACTCAGCTCATCATGTCGCAAATCAAAGCAAGCAACATGCTG
GCTGAAGGCTTTGCTTACAAAATTGAGCAGCTAGAAGATAAAGATTGGGAACGCGAGTGGATGGACAACTTCCACCCAAT
GAAATTTGGTCAGCGTTTGTGGATCTGCCCAAGCTGGCGTGACATTCCCGATCCCACCGCAGTGAACGTGATGCTGGATC
CTGGCCTTGCGTTTGGTACGGGTACTCACCCAACCACAGCACTGTGTCTTGAATGGCTAGAGAGCCTTGATCTTTCGGGT
AAAACCGTTATCGATTTTGGTTGTGGCTCTGGCATCTTGGCGATCGCAGCGATCAAACTGGGTGCAGAAAAAGTCATCGG
GATCGACATTGATCCTCAAGCACTTCTCGCTTCGAAAGACAACGCCCAACGTAATGGCGTTGCCGATCAACTGGATGTTT
ATCTGCCTCAAGATCAACCGGAAGGTCTGCTTGCTGACGTTGTTGTCGCAAACATTTTGGCGGCACCACTGCGTGAGCTT
TCTTCGATCATCAAGGGGCTTGTCAAACCAAATGGCCAATTAGCGATGTCGGGCGTATTGGATACCCAAGCAGAAGATGT
GGCCAACTATTACCGTGATGAGCTTCACATTGATCCAATCGTTGAGCAAAGTGAATGGTGTCGCATCTCTGGTCGCAAGC
AAGGCTAG

Upstream 100 bases:

>100_bases
TGCCCACTTCGGTGGGCATTTTTCATTGAGCGGATTTTTTCGTTTGCAGGGAAAGTCTGCTAAACTCTGCGCCAAATTTA
AACATTAAGAGTATGCACTC

Downstream 100 bases:

>100_bases
ACAAGACTTTCAGGGGTAATTGTTTGAAATTCATACAAATTGCAAAAACAATTTGTCAATGCTCAAATATTAGTCTTTTC
ACGCAGAAAAAAAATGCGTA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MPWIQIKLNATNENAELIGDMLMEETGALSVTFLDAHDTPVFEPLPGETRLWGDTDVLALYDAEADTQLIMSQIKASNML
AEGFAYKIEQLEDKDWEREWMDNFHPMKFGQRLWICPSWRDIPDPTAVNVMLDPGLAFGTGTHPTTALCLEWLESLDLSG
KTVIDFGCGSGILAIAAIKLGAEKVIGIDIDPQALLASKDNAQRNGVADQLDVYLPQDQPEGLLADVVVANILAAPLREL
SSIIKGLVKPNGQLAMSGVLDTQAEDVANYYRDELHIDPIVEQSEWCRISGRKQG

Sequences:

>Translated_295_residues
MPWIQIKLNATNENAELIGDMLMEETGALSVTFLDAHDTPVFEPLPGETRLWGDTDVLALYDAEADTQLIMSQIKASNML
AEGFAYKIEQLEDKDWEREWMDNFHPMKFGQRLWICPSWRDIPDPTAVNVMLDPGLAFGTGTHPTTALCLEWLESLDLSG
KTVIDFGCGSGILAIAAIKLGAEKVIGIDIDPQALLASKDNAQRNGVADQLDVYLPQDQPEGLLADVVVANILAAPLREL
SSIIKGLVKPNGQLAMSGVLDTQAEDVANYYRDELHIDPIVEQSEWCRISGRKQG
>Mature_294_residues
PWIQIKLNATNENAELIGDMLMEETGALSVTFLDAHDTPVFEPLPGETRLWGDTDVLALYDAEADTQLIMSQIKASNMLA
EGFAYKIEQLEDKDWEREWMDNFHPMKFGQRLWICPSWRDIPDPTAVNVMLDPGLAFGTGTHPTTALCLEWLESLDLSGK
TVIDFGCGSGILAIAAIKLGAEKVIGIDIDPQALLASKDNAQRNGVADQLDVYLPQDQPEGLLADVVVANILAAPLRELS
SIIKGLVKPNGQLAMSGVLDTQAEDVANYYRDELHIDPIVEQSEWCRISGRKQG

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=294, Percent_Identity=70.0680272108844, Blast_Score=408, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_VIBVU (Q8DD03)

Other databases:

- EMBL:   AE016795
- RefSeq:   NP_760163.1
- ProteinModelPortal:   Q8DD03
- SMR:   Q8DD03
- GeneID:   1178153
- GenomeReviews:   AE016795_GR
- KEGG:   vvu:VV1_1233
- HOGENOM:   HBG584653
- OMA:   EDQDWER
- ProtClustDB:   PRK00517
- BioCyc:   VVUL216895:VV1_1233-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32462; Mature: 32331

Theoretical pI: Translated: 4.05; Mature: 4.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWIQIKLNATNENAELIGDMLMEETGALSVTFLDAHDTPVFEPLPGETRLWGDTDVLAL
CCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEECCCCCEEEE
YDAEADTQLIMSQIKASNMLAEGFAYKIEQLEDKDWEREWMDNFHPMKFGQRLWICPSWR
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCEEEECCCCC
DIPDPTAVNVMLDPGLAFGTGTHPTTALCLEWLESLDLSGKTVIDFGCGSGILAIAAIKL
CCCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHH
GAEKVIGIDIDPQALLASKDNAQRNGVADQLDVYLPQDQPEGLLADVVVANILAAPLREL
CCCEEEEECCCCHHHHCCCCCCCCCCCCHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
SSIIKGLVKPNGQLAMSGVLDTQAEDVANYYRDELHIDPIVEQSEWCRISGRKQG
HHHHHHHHCCCCCEEEECHHCCHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCC
>Mature Secondary Structure 
PWIQIKLNATNENAELIGDMLMEETGALSVTFLDAHDTPVFEPLPGETRLWGDTDVLAL
CEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEECCCCCEEEE
YDAEADTQLIMSQIKASNMLAEGFAYKIEQLEDKDWEREWMDNFHPMKFGQRLWICPSWR
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCEEEECCCCC
DIPDPTAVNVMLDPGLAFGTGTHPTTALCLEWLESLDLSGKTVIDFGCGSGILAIAAIKL
CCCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHH
GAEKVIGIDIDPQALLASKDNAQRNGVADQLDVYLPQDQPEGLLADVVVANILAAPLREL
CCCEEEEECCCCHHHHCCCCCCCCCCCCHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
SSIIKGLVKPNGQLAMSGVLDTQAEDVANYYRDELHIDPIVEQSEWCRISGRKQG
HHHHHHHHCCCCCEEEECHHCCHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA