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The map label for this gene is recQ [H]

Identifier: 27364385

GI number: 27364385

Start: 949776

End: 951611

Strand: Reverse

Name: recQ [H]

Synonym: VV1_0943

Alternate gene names: 27364385

Gene position: 951611-949776 (Counterclockwise)

Preceding gene: 27364389

Following gene: 27364384

Centisome position: 29.0

GC content: 51.09

Gene sequence:

>1836_bases
ATGACTTCCACGCTGCTTGCCGACCCTTCCGATGGCTCGATGACGCCCCAAAGCGTTTTATCACAGGTGTTCGGCTATCA
GACCTTCCGTGAGGGGCAGCAGTCGGTGATCGAGGCGGCTGTTGAGGGGAAAGATAGTTTGGTGATCATGCCCACCGGTG
GCGGCAAATCGCTGTGCTATCAAATTCCTGCTCTGGTACGCCCGGGTATTACCTTAGTGATCTCCCCTTTGATTTCGCTG
ATGAAAGATCAGGTTGACCAACTTAAAGCCAATGGTGTCGCGGCAGAATGTGTCAACTCGACCTTATCACGTGACGCTTT
GCTCAGCGTCTACAACCGCATGCACGCGGGACAGCTCAAATTGGTGTACGTTTCGCCAGAGCGGGTGTTGATGCGCGACT
TTATTGAGCGGCTGGAAAATTTGCCCTTGGCGATGATTGCTGTCGATGAAGCGCACTGTATCTCTCAGTGGGGACACGAT
TTCCGCCCCGAGTACGCCGCGTTAGGGCAATTGAAGCATCATTTTCCTCACGTGCCGTTTATGGCGCTAACGGCCACGGC
AGACGATGCGACGCGCAAAGACATTTTAAGTCGCTTACATCTTAATGAGCCTCACGTTTATCTCGGCAGTTTTGATCGCC
CCAACATTCGTTATGACCTAGTGGAGAAGCACAAGCCGGTCTCTCAAGTGATTCGCTATTTGGAAAGCCAGAAAGGCAAT
TGCGGCATTATTTATTGTGGTAGCCGTAAGAAAGTCGAAATGCTGACCGAGAAGCTGTGCAACAACCATATTCGAGCGGC
GGGTTATCACGCTGGTATGGACGCCGATGAGCGCGCTTATGTGCAAGAAGCGTTTCAACGAGACGACATCCAGATTGTGG
TGGCGACAGTGGCCTTTGGTATGGGGATCAACAAACCCAATGTGCGCTTTGTGGTGCATTTTGATATTCCACGCAATATC
GAATCGTACTATCAAGAGACGGGTCGAGCAGGGCGTGATGGCCTGCCCGCCGAAGCAATGATGCTCTACGATCCGGCAGA
CATCACTTGGTTGCGCCGCATGTTGGATGAGAAAGACGACGGCCCGCAAAAACAAGTGGAAAGTCATAAGCTCAATGCCA
TGAGTGCCTTTGCTGAGGCGCAAACCTGTCGCCGCCAAGTGCTGCTGAACTATTTCGGTGAATACCGCGAGAAGCCTTGC
GGCAATTGCGATATTTGCTTAGACCCGCCGAAGCATTTTGATGCGACGGAAGAAGCACGCAAAGCGTTGTCGTGTGTTTA
TCGCGTTAATCAGAGTTTTGGTATGGGCTACGTAGTGGAAGTGTTGCGTGGGATGCAAAACATTCGTATCCGGGAACATG
GCCACGATAAGATTTCGACCTACGGTTTAGGGCGTGATCACAGCCATGACTATTGGGTGAGCATTTTCCGCCAACTGATC
CACAAAGGGCTGCTGTTTCAAAACATCACCCGCAATTCGACTTTGCAGTTAACTGAAGAAGCAAGGCCATTGCTGCGTGG
TGATATGACGTTGGAGCTGGCGGTGCCACGTTTAGATACTGCCGCGCGCAGTGCCAAAGCAGATAAGCTATCGAACAAAC
ATTACGACAAAAAGCTGTTCGCCAAATTACGTAAGCTACGCAAATCGATTGCCGATGAGGAAGAGATCCCACCCTATGTG
GTGTTCAGTGATGCCACGCTGATCGACATGGCTGAAATATTGCCGACTTCATATGGTGAAATGCTCGCGGTGAGCGGCGT
CGGGCAGCGCAAACTAGAAAAATACGCGGATCCGTTTTTAGATTTGATTCAGGAGCACATCACTCATTATGGATGA

Upstream 100 bases:

>100_bases
TCACCATCAAACGCCATTACAATGTGCCCTCATTATCTTGGGCATTTCGCAATATTGAGTGCTTTCGAGACCACCATCAA
GACCAATACTGAGACTGTTC

Downstream 100 bases:

>100_bases
GAACAACAAGGAATTTGGTTTAACGGAATACATGGCGCAAGAAGGTCGATTGTTGATTCGCACGCCACGCTTTAATCTTG
ATACCTTTCCCGCGCTGGCT

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 611; Mature: 610

Protein sequence:

>611_residues
MTSTLLADPSDGSMTPQSVLSQVFGYQTFREGQQSVIEAAVEGKDSLVIMPTGGGKSLCYQIPALVRPGITLVISPLISL
MKDQVDQLKANGVAAECVNSTLSRDALLSVYNRMHAGQLKLVYVSPERVLMRDFIERLENLPLAMIAVDEAHCISQWGHD
FRPEYAALGQLKHHFPHVPFMALTATADDATRKDILSRLHLNEPHVYLGSFDRPNIRYDLVEKHKPVSQVIRYLESQKGN
CGIIYCGSRKKVEMLTEKLCNNHIRAAGYHAGMDADERAYVQEAFQRDDIQIVVATVAFGMGINKPNVRFVVHFDIPRNI
ESYYQETGRAGRDGLPAEAMMLYDPADITWLRRMLDEKDDGPQKQVESHKLNAMSAFAEAQTCRRQVLLNYFGEYREKPC
GNCDICLDPPKHFDATEEARKALSCVYRVNQSFGMGYVVEVLRGMQNIRIREHGHDKISTYGLGRDHSHDYWVSIFRQLI
HKGLLFQNITRNSTLQLTEEARPLLRGDMTLELAVPRLDTAARSAKADKLSNKHYDKKLFAKLRKLRKSIADEEEIPPYV
VFSDATLIDMAEILPTSYGEMLAVSGVGQRKLEKYADPFLDLIQEHITHYG

Sequences:

>Translated_611_residues
MTSTLLADPSDGSMTPQSVLSQVFGYQTFREGQQSVIEAAVEGKDSLVIMPTGGGKSLCYQIPALVRPGITLVISPLISL
MKDQVDQLKANGVAAECVNSTLSRDALLSVYNRMHAGQLKLVYVSPERVLMRDFIERLENLPLAMIAVDEAHCISQWGHD
FRPEYAALGQLKHHFPHVPFMALTATADDATRKDILSRLHLNEPHVYLGSFDRPNIRYDLVEKHKPVSQVIRYLESQKGN
CGIIYCGSRKKVEMLTEKLCNNHIRAAGYHAGMDADERAYVQEAFQRDDIQIVVATVAFGMGINKPNVRFVVHFDIPRNI
ESYYQETGRAGRDGLPAEAMMLYDPADITWLRRMLDEKDDGPQKQVESHKLNAMSAFAEAQTCRRQVLLNYFGEYREKPC
GNCDICLDPPKHFDATEEARKALSCVYRVNQSFGMGYVVEVLRGMQNIRIREHGHDKISTYGLGRDHSHDYWVSIFRQLI
HKGLLFQNITRNSTLQLTEEARPLLRGDMTLELAVPRLDTAARSAKADKLSNKHYDKKLFAKLRKLRKSIADEEEIPPYV
VFSDATLIDMAEILPTSYGEMLAVSGVGQRKLEKYADPFLDLIQEHITHYG
>Mature_610_residues
TSTLLADPSDGSMTPQSVLSQVFGYQTFREGQQSVIEAAVEGKDSLVIMPTGGGKSLCYQIPALVRPGITLVISPLISLM
KDQVDQLKANGVAAECVNSTLSRDALLSVYNRMHAGQLKLVYVSPERVLMRDFIERLENLPLAMIAVDEAHCISQWGHDF
RPEYAALGQLKHHFPHVPFMALTATADDATRKDILSRLHLNEPHVYLGSFDRPNIRYDLVEKHKPVSQVIRYLESQKGNC
GIIYCGSRKKVEMLTEKLCNNHIRAAGYHAGMDADERAYVQEAFQRDDIQIVVATVAFGMGINKPNVRFVVHFDIPRNIE
SYYQETGRAGRDGLPAEAMMLYDPADITWLRRMLDEKDDGPQKQVESHKLNAMSAFAEAQTCRRQVLLNYFGEYREKPCG
NCDICLDPPKHFDATEEARKALSCVYRVNQSFGMGYVVEVLRGMQNIRIREHGHDKISTYGLGRDHSHDYWVSIFRQLIH
KGLLFQNITRNSTLQLTEEARPLLRGDMTLELAVPRLDTAARSAKADKLSNKHYDKKLFAKLRKLRKSIADEEEIPPYVV
FSDATLIDMAEILPTSYGEMLAVSGVGQRKLEKYADPFLDLIQEHITHYG

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=635, Percent_Identity=34.0157480314961, Blast_Score=345, Evalue=7e-95,
Organism=Homo sapiens, GI110735439, Length=519, Percent_Identity=36.9942196531792, Blast_Score=323, Evalue=3e-88,
Organism=Homo sapiens, GI169218196, Length=519, Percent_Identity=36.9942196531792, Blast_Score=322, Evalue=4e-88,
Organism=Homo sapiens, GI14591902, Length=529, Percent_Identity=35.1606805293006, Blast_Score=306, Evalue=4e-83,
Organism=Homo sapiens, GI14591904, Length=529, Percent_Identity=35.1606805293006, Blast_Score=306, Evalue=4e-83,
Organism=Homo sapiens, GI148612816, Length=519, Percent_Identity=35.4527938342967, Blast_Score=286, Evalue=4e-77,
Organism=Homo sapiens, GI51242947, Length=368, Percent_Identity=41.5760869565217, Blast_Score=273, Evalue=2e-73,
Organism=Homo sapiens, GI51242943, Length=368, Percent_Identity=41.5760869565217, Blast_Score=273, Evalue=3e-73,
Organism=Homo sapiens, GI284005309, Length=367, Percent_Identity=36.7847411444142, Blast_Score=213, Evalue=6e-55,
Organism=Homo sapiens, GI222352149, Length=336, Percent_Identity=24.702380952381, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI7661920, Length=350, Percent_Identity=22.2857142857143, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI4758138, Length=365, Percent_Identity=23.8356164383562, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI13514831, Length=357, Percent_Identity=23.8095238095238, Blast_Score=73, Evalue=9e-13,
Organism=Homo sapiens, GI148613856, Length=345, Percent_Identity=23.4782608695652, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI38201710, Length=345, Percent_Identity=23.4782608695652, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI164664518, Length=339, Percent_Identity=25.3687315634218, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI48994977, Length=591, Percent_Identity=64.8054145516074, Blast_Score=825, Evalue=0.0,
Organism=Escherichia coli, GI87082221, Length=346, Percent_Identity=23.4104046242775, Blast_Score=69, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25145561, Length=646, Percent_Identity=34.2105263157895, Blast_Score=346, Evalue=2e-95,
Organism=Caenorhabditis elegans, GI32564293, Length=688, Percent_Identity=30.3779069767442, Blast_Score=294, Evalue=1e-79,
Organism=Caenorhabditis elegans, GI71987997, Length=403, Percent_Identity=38.2133995037221, Blast_Score=289, Evalue=4e-78,
Organism=Caenorhabditis elegans, GI71987993, Length=405, Percent_Identity=38.2716049382716, Blast_Score=288, Evalue=4e-78,
Organism=Caenorhabditis elegans, GI17552866, Length=442, Percent_Identity=34.841628959276, Blast_Score=255, Evalue=6e-68,
Organism=Caenorhabditis elegans, GI71995724, Length=350, Percent_Identity=22.5714285714286, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17507121, Length=350, Percent_Identity=22.2857142857143, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71987143, Length=364, Percent_Identity=25.5494505494505, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32565321, Length=170, Percent_Identity=30, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17537549, Length=377, Percent_Identity=23.6074270557029, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17552114, Length=350, Percent_Identity=25.1428571428571, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115533224, Length=351, Percent_Identity=23.3618233618234, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17555296, Length=351, Percent_Identity=23.0769230769231, Blast_Score=65, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6323844, Length=521, Percent_Identity=39.9232245681382, Blast_Score=355, Evalue=2e-98,
Organism=Saccharomyces cerevisiae, GI6320224, Length=380, Percent_Identity=23.6842105263158, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320041, Length=328, Percent_Identity=24.390243902439, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324217, Length=324, Percent_Identity=24.0740740740741, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321856, Length=343, Percent_Identity=23.9067055393586, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646066, Length=633, Percent_Identity=34.7551342812006, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24664226, Length=449, Percent_Identity=36.9710467706013, Blast_Score=284, Evalue=2e-76,
Organism=Drosophila melanogaster, GI62472181, Length=449, Percent_Identity=36.9710467706013, Blast_Score=280, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24664230, Length=451, Percent_Identity=36.5853658536585, Blast_Score=280, Evalue=2e-75,
Organism=Drosophila melanogaster, GI21358123, Length=386, Percent_Identity=37.3056994818653, Blast_Score=219, Evalue=3e-57,
Organism=Drosophila melanogaster, GI28574962, Length=334, Percent_Identity=25.748502994012, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583281, Length=360, Percent_Identity=25.2777777777778, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24645031, Length=354, Percent_Identity=23.1638418079096, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24583279, Length=352, Percent_Identity=26.1363636363636, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21355075, Length=341, Percent_Identity=20.8211143695015, Blast_Score=66, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 69021; Mature: 68890

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTLLADPSDGSMTPQSVLSQVFGYQTFREGQQSVIEAAVEGKDSLVIMPTGGGKSLCY
CCCCEECCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHH
QIPALVRPGITLVISPLISLMKDQVDQLKANGVAAECVNSTLSRDALLSVYNRMHAGQLK
HCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LVYVSPERVLMRDFIERLENLPLAMIAVDEAHCISQWGHDFRPEYAALGQLKHHFPHVPF
EEEECHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCC
MALTATADDATRKDILSRLHLNEPHVYLGSFDRPNIRYDLVEKHKPVSQVIRYLESQKGN
EEEEECCCHHHHHHHHHHHCCCCCCEEECCCCCCCCEEHHHHHCCCHHHHHHHHHCCCCC
CGIIYCGSRKKVEMLTEKLCNNHIRAAGYHAGMDADERAYVQEAFQRDDIQIVVATVAFG
EEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEHHHHHHHH
MGINKPNVRFVVHFDIPRNIESYYQETGRAGRDGLPAEAMMLYDPADITWLRRMLDEKDD
CCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCC
GPQKQVESHKLNAMSAFAEAQTCRRQVLLNYFGEYREKPCGNCDICLDPPKHFDATEEAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCHHHHH
KALSCVYRVNQSFGMGYVVEVLRGMQNIRIREHGHDKISTYGLGRDHSHDYWVSIFRQLI
HHHHHHHHHHCCCCHHHHHHHHHHHHHCEEHHCCCCCHHHCCCCCCCCCHHHHHHHHHHH
HKGLLFQNITRNSTLQLTEEARPLLRGDMTLELAVPRLDTAARSAKADKLSNKHYDKKLF
HHHHHHHHCCCCCCEEEHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHH
AKLRKLRKSIADEEEIPPYVVFSDATLIDMAEILPTSYGEMLAVSGVGQRKLEKYADPFL
HHHHHHHHHHCCHHCCCCEEEECCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHH
DLIQEHITHYG
HHHHHHHHCCC
>Mature Secondary Structure 
TSTLLADPSDGSMTPQSVLSQVFGYQTFREGQQSVIEAAVEGKDSLVIMPTGGGKSLCY
CCCEECCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHH
QIPALVRPGITLVISPLISLMKDQVDQLKANGVAAECVNSTLSRDALLSVYNRMHAGQLK
HCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LVYVSPERVLMRDFIERLENLPLAMIAVDEAHCISQWGHDFRPEYAALGQLKHHFPHVPF
EEEECHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCC
MALTATADDATRKDILSRLHLNEPHVYLGSFDRPNIRYDLVEKHKPVSQVIRYLESQKGN
EEEEECCCHHHHHHHHHHHCCCCCCEEECCCCCCCCEEHHHHHCCCHHHHHHHHHCCCCC
CGIIYCGSRKKVEMLTEKLCNNHIRAAGYHAGMDADERAYVQEAFQRDDIQIVVATVAFG
EEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEHHHHHHHH
MGINKPNVRFVVHFDIPRNIESYYQETGRAGRDGLPAEAMMLYDPADITWLRRMLDEKDD
CCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCC
GPQKQVESHKLNAMSAFAEAQTCRRQVLLNYFGEYREKPCGNCDICLDPPKHFDATEEAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCHHHHH
KALSCVYRVNQSFGMGYVVEVLRGMQNIRIREHGHDKISTYGLGRDHSHDYWVSIFRQLI
HHHHHHHHHHCCCCHHHHHHHHHHHHHCEEHHCCCCCHHHCCCCCCCCCHHHHHHHHHHH
HKGLLFQNITRNSTLQLTEEARPLLRGDMTLELAVPRLDTAARSAKADKLSNKHYDKKLF
HHHHHHHHCCCCCCEEEHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHH
AKLRKLRKSIADEEEIPPYVVFSDATLIDMAEILPTSYGEMLAVSGVGQRKLEKYADPFL
HHHHHHHHHHCCHHCCCCEEEECCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHH
DLIQEHITHYG
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]