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The map label for this gene is aceB [H]

Identifier: 27363918

GI number: 27363918

Start: 446748

End: 448385

Strand: Reverse

Name: aceB [H]

Synonym: VV1_0450

Alternate gene names: 27363918

Gene position: 448385-446748 (Counterclockwise)

Preceding gene: 27363919

Following gene: 27363917

Centisome position: 13.66

GC content: 46.89

Gene sequence:

>1638_bases
ATGATGCTTGCTCAAACGCCCGAAAAAGAAAACACACAGGCTGAACAACAGACCCAAGGCATGCTTGAAGTAACAGGAAC
CCTGTCTCCTGAACATCAAGCTATTTTCCCTGTTGAAGCCCAAACCTTTTTATCTCAGCTGTGTGAGCGATTCTCATTGC
GCGTCGATCAATTGTTAACTGCCCGTGAAGAGAGACAGAACAAGATCGATCAAGGAGAGTTACCTGATTTTCTTACAGAG
ACTCAGGATATTCGAGAAGGGAGCTGGAAAATTTTGGGGATTCCCAACGATCTGCAAGATCGTCGAGTCGAAATTACCGG
GCCAACCGATCGTAAAATGGTGATCAACGCCCTAAACGCCAATGTAAAAGTCTTTATGGCGGATTTCGAAGACTCGATGT
CTCCAGCTTGGGATAAGGTGTTGGATGGCCAGATCAACTTGCGTGATGCGGTCAATGGCACCATCTCCTATTCCAACCCC
GATAATGGCAAGCATTATCAGCTGGGCAACGATCCAGCGGTGTTGATCTGCCGTGTCCGCGGTCTTCATTTAAAAGAAAA
GCATGTGACGTGGCGCGGTCAGATCATTCCAGGTTCCTTATTTGATTTTGCTCTTTATTTCTTTAACAACCACAAAGCGT
TGTTGAAAAAAGGCAGTGGTCCTTATTTCTATCTTCCTAAGTTACAGTCTCATCATGAGGCGAAATGGTGGAGTGAAGTG
TTCCATTTCACCGAAGAGTATTTCGGTTTGGATACTGGCACTATCAAAGCCACGGTATTGATCGAGACGCTGCCTGCCGT
CTTTGAAATGGATGAGATTCTCTTCTCGTTAAAAGAGCATATTGTTGGCCTCAACTGTGGCCGTTGGGATTACATTTTTA
GCTATATCAAAACACTGAAAAAGCACCCAGACCGTGTGCTGCCTGATCGTCAGGTGGTTACCATGGACAAGCCGTTCCTC
AATGCTTACTCGCGTTTACTTGTCCGCACCTGTCATAAACGTGGCGCGTTTGCGATGGGAGGGATGGCTGCCTTTATCCC
AGCCAAAGATCCACAAGAGAATCAAAAGGTATTGGATAAGATCCAGAACGATAAATCACTCGAAGCCAGCAATGGCCATG
ATGGCACTTGGGTTGCGCATCCTGGTTTAGCCGACACCGCCATGGACGTGTTTAATCGTGCTCTAGGTGAGCGTAAAAAC
CAGCTTGATGTCACTCGCCAAGACGATGCGCCGATTACAGCTAAACAGTTACTTGAGCCTTGTGATGGAGCAAGAACAGA
ACAAGGTATGAGACACAATATTCGTGTTGCATTGCAGTACATAGAGGCGTGGATCTCGGGGAATGGCTGTGTACCGATTT
ATGGCTTGATGGAAGATGCAGCGACCGCAGAGATCTCACGCGCTTCTATCTGGCAGTGGATTCAACATAGTAAGTCGTTA
GATAACGGTGAAGTGGTGACCAAAGCGTTGTTTAAGCGTTATCTCGACGAAGAGATTCAAGTCGTAAAACAAGAAGTGGG
GGAGACTCGTTTTGACTCAGGCCGTTTCCATGAAGCCGCCGAATTGATGGCTAGCCTGACCACCAGTGATGAGCTAACCA
ACTTCTTAACCGTACCGGGTTATGACTACCTAGATTAA

Upstream 100 bases:

>100_bases
CTGGATGGATTTTTGAACAAAGTGATGGTTTGGTTTTTGTGGTTTAAAACTTACAAATGTTGTTCTGGAATCGTCGTAAA
GCAAAATGAAAGGAAGAAGA

Downstream 100 bases:

>100_bases
TGAGTAAACCAATCAACAACTAATAACGTGAACCTTCATTGGCGGAGCAGGATGTACCGCTAACGAAATGGAATATATAG
CGCACTCAATTTTAATAATC

Product: malate synthase

Products: NA

Alternate protein names: MSA [H]

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MMLAQTPEKENTQAEQQTQGMLEVTGTLSPEHQAIFPVEAQTFLSQLCERFSLRVDQLLTAREERQNKIDQGELPDFLTE
TQDIREGSWKILGIPNDLQDRRVEITGPTDRKMVINALNANVKVFMADFEDSMSPAWDKVLDGQINLRDAVNGTISYSNP
DNGKHYQLGNDPAVLICRVRGLHLKEKHVTWRGQIIPGSLFDFALYFFNNHKALLKKGSGPYFYLPKLQSHHEAKWWSEV
FHFTEEYFGLDTGTIKATVLIETLPAVFEMDEILFSLKEHIVGLNCGRWDYIFSYIKTLKKHPDRVLPDRQVVTMDKPFL
NAYSRLLVRTCHKRGAFAMGGMAAFIPAKDPQENQKVLDKIQNDKSLEASNGHDGTWVAHPGLADTAMDVFNRALGERKN
QLDVTRQDDAPITAKQLLEPCDGARTEQGMRHNIRVALQYIEAWISGNGCVPIYGLMEDAATAEISRASIWQWIQHSKSL
DNGEVVTKALFKRYLDEEIQVVKQEVGETRFDSGRFHEAAELMASLTTSDELTNFLTVPGYDYLD

Sequences:

>Translated_545_residues
MMLAQTPEKENTQAEQQTQGMLEVTGTLSPEHQAIFPVEAQTFLSQLCERFSLRVDQLLTAREERQNKIDQGELPDFLTE
TQDIREGSWKILGIPNDLQDRRVEITGPTDRKMVINALNANVKVFMADFEDSMSPAWDKVLDGQINLRDAVNGTISYSNP
DNGKHYQLGNDPAVLICRVRGLHLKEKHVTWRGQIIPGSLFDFALYFFNNHKALLKKGSGPYFYLPKLQSHHEAKWWSEV
FHFTEEYFGLDTGTIKATVLIETLPAVFEMDEILFSLKEHIVGLNCGRWDYIFSYIKTLKKHPDRVLPDRQVVTMDKPFL
NAYSRLLVRTCHKRGAFAMGGMAAFIPAKDPQENQKVLDKIQNDKSLEASNGHDGTWVAHPGLADTAMDVFNRALGERKN
QLDVTRQDDAPITAKQLLEPCDGARTEQGMRHNIRVALQYIEAWISGNGCVPIYGLMEDAATAEISRASIWQWIQHSKSL
DNGEVVTKALFKRYLDEEIQVVKQEVGETRFDSGRFHEAAELMASLTTSDELTNFLTVPGYDYLD
>Mature_545_residues
MMLAQTPEKENTQAEQQTQGMLEVTGTLSPEHQAIFPVEAQTFLSQLCERFSLRVDQLLTAREERQNKIDQGELPDFLTE
TQDIREGSWKILGIPNDLQDRRVEITGPTDRKMVINALNANVKVFMADFEDSMSPAWDKVLDGQINLRDAVNGTISYSNP
DNGKHYQLGNDPAVLICRVRGLHLKEKHVTWRGQIIPGSLFDFALYFFNNHKALLKKGSGPYFYLPKLQSHHEAKWWSEV
FHFTEEYFGLDTGTIKATVLIETLPAVFEMDEILFSLKEHIVGLNCGRWDYIFSYIKTLKKHPDRVLPDRQVVTMDKPFL
NAYSRLLVRTCHKRGAFAMGGMAAFIPAKDPQENQKVLDKIQNDKSLEASNGHDGTWVAHPGLADTAMDVFNRALGERKN
QLDVTRQDDAPITAKQLLEPCDGARTEQGMRHNIRVALQYIEAWISGNGCVPIYGLMEDAATAEISRASIWQWIQHSKSL
DNGEVVTKALFKRYLDEEIQVVKQEVGETRFDSGRFHEAAELMASLTTSDELTNFLTVPGYDYLD

Specific function: Glyoxylate bypass; second step. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1790444, Length=523, Percent_Identity=71.8929254302103, Blast_Score=798, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17561814, Length=538, Percent_Identity=49.0706319702602, Blast_Score=493, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI71982926, Length=432, Percent_Identity=51.1574074074074, Blast_Score=404, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6324212, Length=517, Percent_Identity=45.6479690522244, Blast_Score=441, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6322222, Length=517, Percent_Identity=45.4545454545455, Blast_Score=439, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR006252
- InterPro:   IPR001465
- InterPro:   IPR019830 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 61871; Mature: 61871

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00510 MALATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLAQTPEKENTQAEQQTQGMLEVTGTLSPEHQAIFPVEAQTFLSQLCERFSLRVDQLLT
CCCCCCCCCCCCHHHHHHCCCEEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHH
AREERQNKIDQGELPDFLTETQDIREGSWKILGIPNDLQDRRVEITGPTDRKMVINALNA
HHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCCHHHHHEECC
NVKVFMADFEDSMSPAWDKVLDGQINLRDAVNGTISYSNPDNGKHYQLGNDPAVLICRVR
CEEEEEECCCCCCCHHHHHHHCCCEEEHHCCCCEEEECCCCCCCCEECCCCCEEEEEEEC
GLHLKEKHVTWRGQIIPGSLFDFALYFFNNHKALLKKGSGPYFYLPKLQSHHEAKWWSEV
CCEEECCCCEEECEECCCHHHHHHHHHHCCCHHHHCCCCCCEEECCCCCCCCHHHHHHHH
FHFTEEYFGLDTGTIKATVLIETLPAVFEMDEILFSLKEHIVGLNCGRWDYIFSYIKTLK
HHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
KHPDRVLPDRQVVTMDKPFLNAYSRLLVRTCHKRGAFAMGGMAAFIPAKDPQENQKVLDK
HCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCEEECCEEEECCCCCCCHHHHHHHH
IQNDKSLEASNGHDGTWVAHPGLADTAMDVFNRALGERKNQLDVTRQDDAPITAKQLLEP
HCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCC
CDGARTEQGMRHNIRVALQYIEAWISGNGCVPIYGLMEDAATAEISRASIWQWIQHSKSL
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC
DNGEVVTKALFKRYLDEEIQVVKQEVGETRFDSGRFHEAAELMASLTTSDELTNFLTVPG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHEEECCC
YDYLD
CCCCC
>Mature Secondary Structure
MMLAQTPEKENTQAEQQTQGMLEVTGTLSPEHQAIFPVEAQTFLSQLCERFSLRVDQLLT
CCCCCCCCCCCCHHHHHHCCCEEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHH
AREERQNKIDQGELPDFLTETQDIREGSWKILGIPNDLQDRRVEITGPTDRKMVINALNA
HHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCCHHHHHEECC
NVKVFMADFEDSMSPAWDKVLDGQINLRDAVNGTISYSNPDNGKHYQLGNDPAVLICRVR
CEEEEEECCCCCCCHHHHHHHCCCEEEHHCCCCEEEECCCCCCCCEECCCCCEEEEEEEC
GLHLKEKHVTWRGQIIPGSLFDFALYFFNNHKALLKKGSGPYFYLPKLQSHHEAKWWSEV
CCEEECCCCEEECEECCCHHHHHHHHHHCCCHHHHCCCCCCEEECCCCCCCCHHHHHHHH
FHFTEEYFGLDTGTIKATVLIETLPAVFEMDEILFSLKEHIVGLNCGRWDYIFSYIKTLK
HHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
KHPDRVLPDRQVVTMDKPFLNAYSRLLVRTCHKRGAFAMGGMAAFIPAKDPQENQKVLDK
HCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCEEECCEEEECCCCCCCHHHHHHHH
IQNDKSLEASNGHDGTWVAHPGLADTAMDVFNRALGERKNQLDVTRQDDAPITAKQLLEP
HCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCC
CDGARTEQGMRHNIRVALQYIEAWISGNGCVPIYGLMEDAATAEISRASIWQWIQHSKSL
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC
DNGEVVTKALFKRYLDEEIQVVKQEVGETRFDSGRFHEAAELMASLTTSDELTNFLTVPG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHEEECCC
YDYLD
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3050899; 3060852; 8265357; 9278503 [H]