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The map label for this gene is iolF

Identifier: 255767851

GI number: 255767851

Start: 4076842

End: 4078158

Strand: Reverse

Name: iolF

Synonym: BSU39710

Alternate gene names: 255767851

Gene position: 4078158-4076842 (Counterclockwise)

Preceding gene: 16081023

Following gene: 255767850

Centisome position: 96.74

GC content: 49.13

Gene sequence:

>1317_bases
ATGGGCAATACCAATGGAGATTCAGCCTTCAATAAACGGACAATCGCGGCAGCATTGGCCAACTATATTGATGCCGGTTC
AATTGTGGCAGGCTCCGCCGGTTTATCATTATGGGTCAGTTACCTTAAGCTATCCGATACGCAAATCGGGCTGCTCGGCG
CGTTGAGCGCAAATGCGATTTCTGCCGCTGTCGGCGCGCTGCTTGGCGGGTTTCTGGCTGATAAAGTCGGACGGAAGGCT
GTTTATACCAATAGTATGCTGGTTTATGCACTAGGGATTTGTTTGGTTTTGTTCGGGGTTAATTTCCCCATGTTGTTAAG
CGGTTACATCATTATCGGTTTATCAGTAGGGGCTGACATAACCGCGTCATGGACCATTATTGCGGAAAATGCGCCAAAGA
AGAATCGGGCCAGGCATTGCGGCGTAGCACAAGTCGCTTGGGCCGCGGGCGCTGTCGTTGTACTGCTCCTCTCCGTACTG
GCCGGTGACTTGGGACTCTTGGGGAATAAAATCGTATTTGCCCATCTGCTTGTGATTGCGCTGATTACGTACATCCTGAG
AATCAGGCTTCCGGAATCAGACGCCTGGCAGACAAAAAATCAGCCGGAGGAAGCTCAGGCAGAGAAGCCGGCTGTATTGA
ATAAGACATCGTATTTTGATTTGCTCAAGCCTATGTATCTAAAAAGCATCCTGTTTTTGATGGGTGTGTACTTGGTTTGG
AACCTAGCCGCCGGGGTCATGGGCTTCTTTATGCCATACATTTATCAGCAGGTCGGCGGTGTATCTGCCAACATGGCCAA
CCTTTTGCAAATGGGGCTGTTTATCTTCACAGGATTGGGGGTCGCCTTGATCTTCATGCCCTTTGCCGACAAATATAGAA
AAACCGTATTTGGAATCGCCGCTTTCATGGCGGTGATCGGGTGGACACTGTTTCTGCTGCCAGTTGAAGGCCTGCCGATT
CTGCTCCTGTTTATTGTCGTGATCGGCATCAATAACGGAGCCGGGCAGCAAGCGAACTATCAGTTATGGGCCAGCGAAAT
CTTTCCTACGCAATATCGTGCTTCCGCACAAGGACTGATGTTTTTCCTTGTCCGTATTTCAATAGGGATTTGGAGTCTGT
TTGTCCCAATGATTATCACCAATTTCGGCATTGGAACGATGGCTGCAATTCTTCTCGGATGTGTGACGGCCAGTATGATC
ATCGGGCTGCTCTTTGCGCCGAATACGTCTGGCAAGTCGCTTGAACAAATTCAAGAGGAACTCTACGGGTCTCCTCAGAG
CCAAGTAAAGAAAGGAACAGAAAGCAAAATCATGTAA

Upstream 100 bases:

>100_bases
AACAAGACCCCGATGTTGCAAACCCGCTGGAGTATGCATTGATTGCGAGAAACTATATTGATCAGCAGTTGTTGGATCTG
GCTTAATGGGGAATGAACAT

Downstream 100 bases:

>100_bases
CCAACAGAAGGAGTGGCTGTCAATGAGTTTACGTATTGGCGTAATTGGAACTGGAGCAATCGGAAAAGAACATATTAACC
GTATCACGAACAAGCTGTCA

Product: inositol transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MGNTNGDSAFNKRTIAAALANYIDAGSIVAGSAGLSLWVSYLKLSDTQIGLLGALSANAISAAVGALLGGFLADKVGRKA
VYTNSMLVYALGICLVLFGVNFPMLLSGYIIIGLSVGADITASWTIIAENAPKKNRARHCGVAQVAWAAGAVVVLLLSVL
AGDLGLLGNKIVFAHLLVIALITYILRIRLPESDAWQTKNQPEEAQAEKPAVLNKTSYFDLLKPMYLKSILFLMGVYLVW
NLAAGVMGFFMPYIYQQVGGVSANMANLLQMGLFIFTGLGVALIFMPFADKYRKTVFGIAAFMAVIGWTLFLLPVEGLPI
LLLFIVVIGINNGAGQQANYQLWASEIFPTQYRASAQGLMFFLVRISIGIWSLFVPMIITNFGIGTMAAILLGCVTASMI
IGLLFAPNTSGKSLEQIQEELYGSPQSQVKKGTESKIM

Sequences:

>Translated_438_residues
MGNTNGDSAFNKRTIAAALANYIDAGSIVAGSAGLSLWVSYLKLSDTQIGLLGALSANAISAAVGALLGGFLADKVGRKA
VYTNSMLVYALGICLVLFGVNFPMLLSGYIIIGLSVGADITASWTIIAENAPKKNRARHCGVAQVAWAAGAVVVLLLSVL
AGDLGLLGNKIVFAHLLVIALITYILRIRLPESDAWQTKNQPEEAQAEKPAVLNKTSYFDLLKPMYLKSILFLMGVYLVW
NLAAGVMGFFMPYIYQQVGGVSANMANLLQMGLFIFTGLGVALIFMPFADKYRKTVFGIAAFMAVIGWTLFLLPVEGLPI
LLLFIVVIGINNGAGQQANYQLWASEIFPTQYRASAQGLMFFLVRISIGIWSLFVPMIITNFGIGTMAAILLGCVTASMI
IGLLFAPNTSGKSLEQIQEELYGSPQSQVKKGTESKIM
>Mature_437_residues
GNTNGDSAFNKRTIAAALANYIDAGSIVAGSAGLSLWVSYLKLSDTQIGLLGALSANAISAAVGALLGGFLADKVGRKAV
YTNSMLVYALGICLVLFGVNFPMLLSGYIIIGLSVGADITASWTIIAENAPKKNRARHCGVAQVAWAAGAVVVLLLSVLA
GDLGLLGNKIVFAHLLVIALITYILRIRLPESDAWQTKNQPEEAQAEKPAVLNKTSYFDLLKPMYLKSILFLMGVYLVWN
LAAGVMGFFMPYIYQQVGGVSANMANLLQMGLFIFTGLGVALIFMPFADKYRKTVFGIAAFMAVIGWTLFLLPVEGLPIL
LLFIVVIGINNGAGQQANYQLWASEIFPTQYRASAQGLMFFLVRISIGIWSLFVPMIITNFGIGTMAAILLGCVTASMII
GLLFAPNTSGKSLEQIQEELYGSPQSQVKKGTESKIM

Specific function: Minor myo-inositol uptake transporter

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family

Homologues:

Organism=Escherichia coli, GI1786229, Length=393, Percent_Identity=25.6997455470738, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87082159, Length=374, Percent_Identity=23.7967914438503, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IOLF_BACSU (P42417)

Other databases:

- EMBL:   D14399
- EMBL:   AL009126
- EMBL:   M76431
- PIR:   F69645
- RefSeq:   NP_391850.2
- ProteinModelPortal:   P42417
- EnsemblBacteria:   EBBACT00000002113
- GeneID:   937616
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU39710
- NMPDR:   fig|224308.1.peg.3976
- GenoList:   BSU39710
- GeneTree:   EBGT00070000031937
- HOGENOM:   HBG392000
- ProtClustDB:   CLSK888174
- BioCyc:   BSUB:BSU39710-MONOMER
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 46864; Mature: 46733

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS50850 MFS; PS00216 SUGAR_TRANSPORT_1; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x114eed4c)-; HASH(0x12880f48)-; HASH(0x13a8e9ec)-; HASH(0xdfaca5c)-; HASH(0x1364f5e0)-; HASH(0x12a4a850)-; HASH(0x137dc1dc)-; HASH(0x135e7d1c)-; HASH(0x1312350c)-; HASH(0x125d465c)-; HASH(0x1327815c)-; HASH(0x13306dc8)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNTNGDSAFNKRTIAAALANYIDAGSIVAGSAGLSLWVSYLKLSDTQIGLLGALSANAI
CCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHH
SAAVGALLGGFLADKVGRKAVYTNSMLVYALGICLVLFGVNFPMLLSGYIIIGLSVGADI
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCHHHEEEECCCCC
TASWTIIAENAPKKNRARHCGVAQVAWAAGAVVVLLLSVLAGDLGLLGNKIVFAHLLVIA
EEEEEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LITYILRIRLPESDAWQTKNQPEEAQAEKPAVLNKTSYFDLLKPMYLKSILFLMGVYLVW
HHHHHHHEECCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
NLAAGVMGFFMPYIYQQVGGVSANMANLLQMGLFIFTGLGVALIFMPFADKYRKTVFGIA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFMAVIGWTLFLLPVEGLPILLLFIVVIGINNGAGQQANYQLWASEIFPTQYRASAQGLM
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHH
FFLVRISIGIWSLFVPMIITNFGIGTMAAILLGCVTASMIIGLLFAPNTSGKSLEQIQEE
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LYGSPQSQVKKGTESKIM
HCCCCHHHHHCCCCCCCH
>Mature Secondary Structure 
GNTNGDSAFNKRTIAAALANYIDAGSIVAGSAGLSLWVSYLKLSDTQIGLLGALSANAI
CCCCCCCHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHH
SAAVGALLGGFLADKVGRKAVYTNSMLVYALGICLVLFGVNFPMLLSGYIIIGLSVGADI
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCHHHEEEECCCCC
TASWTIIAENAPKKNRARHCGVAQVAWAAGAVVVLLLSVLAGDLGLLGNKIVFAHLLVIA
EEEEEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LITYILRIRLPESDAWQTKNQPEEAQAEKPAVLNKTSYFDLLKPMYLKSILFLMGVYLVW
HHHHHHHEECCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
NLAAGVMGFFMPYIYQQVGGVSANMANLLQMGLFIFTGLGVALIFMPFADKYRKTVFGIA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFMAVIGWTLFLLPVEGLPILLLFIVVIGINNGAGQQANYQLWASEIFPTQYRASAQGLM
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHH
FFLVRISIGIWSLFVPMIITNFGIGTMAAILLGCVTASMIIGLLFAPNTSGKSLEQIQEE
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LYGSPQSQVKKGTESKIM
HCCCCHHHHHCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7952181; 9384377; 1761221; 11807058