Click here to switch to the map view.

The map label for this gene is citH

Identifier: 255767826

GI number: 255767826

Start: 4010404

End: 4011684

Strand: Direct

Name: citH

Synonym: BSU39060

Alternate gene names: 255767826

Gene position: 4010404-4011684 (Clockwise)

Preceding gene: 255767823

Following gene: 16080961

Centisome position: 95.13

GC content: 51.29

Gene sequence:

>1281_bases
ATGCTTGCCATACTCGGTTTTGTGATGATGATTGTCTTTATGTACCTTATTATGTCTAACCGGCTTTCCGCTCTTATTGC
TTTGATTGTCGTTCCTATTGTGTTTGCCCTGATCAGCGGATTTGGCAAAGATCTCGGCGAGATGATGATTCAGGGCGTTA
CAGACCTCGCCCCTACCGGTATCATGCTGTTATTCGCCATCCTGTATTTCGGCATTATGATTGACTCAGGCCTGTTTGAT
CCTCTCATTGCCAAAATCTTATCGTTTGTCAAAGGAGATCCGTTAAAAATCGCCGTAGGCACAGCGGTTCTGACCATGAC
CATTTCGCTGGACGGAGATGGGACAACAACCTATATGATTACCATTGCAGCGATGCTGCCTCTCTACAAACGGCTCGGCA
TGAACCGTTTGGTGTTAGCGGGAATAGCGATGCTTGGTTCGGGGGTTATGAATATTATCCCGTGGGGCGGGCCGACTGCG
AGGGTTTTGGCTTCCTTAAAATTGGACACGTCAGAGGTCTTTACACCGCTGATTCCCGCTATGATCGCCGGCATTCTCTG
GGTGATCGCCGTTGCTTATATCCTCGGAAAGAAAGAGCGGAAGCGGCTCGGCGTCATTTCGATTGATCACGCACCGTCTT
CCGACCCGGAGGCCGCACCGCTCAAGCGTCCCGCTCTTCAATGGTTTAACCTGCTGCTGACTGTCGCTCTGATGGCCGCA
CTGATCACCAGCCTGCTGCCGCTCCCTGTTCTTTTTATGACTGCGTTCGCCGTTGCCTTGATGGTTAACTATCCAAATGT
CAAAGAGCAGCAGAAACGAATCTCGGCGCATGCGGGTAATGCGTTAAACGTTGTCTCAATGGTGTTTGCTGCGGGCATAT
TCACAGGCATTCTCTCCGGCACAAAAATGGTGGATGCCATGGCGCATTCTCTCGTTTCACTCATCCCTGATGCCATGGGC
CCGCACCTGCCGTTGATCACTGCGATCGTCAGCATGCCCTTCACCTTTTTCATGTCGAATGACGCCTTTTACTTCGGTGT
CCTTCCCATCATCGCCGAAGCCGCTTCCGCTTACGGAATAGACGCCGCTGAAATCGGGAGGGCCTCCTTGCTGGGGCAGC
CTGTGCATCTGCTCAGCCCGCTTGTGCCTTCCACCTATCTATTGGTAGGAATGGCAGGCGTCAGCTTTGGCGACCATCAA
AAATTCACTATTAAATGGGCCGTGGGAACAACGATTGTGATGACCATTGCGGCGCTTTTGATTGGGATTATTTCTTTCTA
A

Upstream 100 bases:

>100_bases
TATAAATATGCGGTCATACACATTTGAAATAAGCCTTCTTCACAGAAAGAAAGGATGGAAGCGCTTACCAAAAAAGCTGT
TGAATAGGGGAGGTCATATC

Downstream 100 bases:

>100_bases
ATGTATGAGCTTGATCGTAGCATTGAGTGAGTACGTGATTTACAGAGGGGAGAAGATCAAATAGGATATTATGAGTGAAT
AGAAGATTCATGCCAACAAC

Product: secondary transporter of divalent metal ions/citrate complexes

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MLAILGFVMMIVFMYLIMSNRLSALIALIVVPIVFALISGFGKDLGEMMIQGVTDLAPTGIMLLFAILYFGIMIDSGLFD
PLIAKILSFVKGDPLKIAVGTAVLTMTISLDGDGTTTYMITIAAMLPLYKRLGMNRLVLAGIAMLGSGVMNIIPWGGPTA
RVLASLKLDTSEVFTPLIPAMIAGILWVIAVAYILGKKERKRLGVISIDHAPSSDPEAAPLKRPALQWFNLLLTVALMAA
LITSLLPLPVLFMTAFAVALMVNYPNVKEQQKRISAHAGNALNVVSMVFAAGIFTGILSGTKMVDAMAHSLVSLIPDAMG
PHLPLITAIVSMPFTFFMSNDAFYFGVLPIIAEAASAYGIDAAEIGRASLLGQPVHLLSPLVPSTYLLVGMAGVSFGDHQ
KFTIKWAVGTTIVMTIAALLIGIISF

Sequences:

>Translated_426_residues
MLAILGFVMMIVFMYLIMSNRLSALIALIVVPIVFALISGFGKDLGEMMIQGVTDLAPTGIMLLFAILYFGIMIDSGLFD
PLIAKILSFVKGDPLKIAVGTAVLTMTISLDGDGTTTYMITIAAMLPLYKRLGMNRLVLAGIAMLGSGVMNIIPWGGPTA
RVLASLKLDTSEVFTPLIPAMIAGILWVIAVAYILGKKERKRLGVISIDHAPSSDPEAAPLKRPALQWFNLLLTVALMAA
LITSLLPLPVLFMTAFAVALMVNYPNVKEQQKRISAHAGNALNVVSMVFAAGIFTGILSGTKMVDAMAHSLVSLIPDAMG
PHLPLITAIVSMPFTFFMSNDAFYFGVLPIIAEAASAYGIDAAEIGRASLLGQPVHLLSPLVPSTYLLVGMAGVSFGDHQ
KFTIKWAVGTTIVMTIAALLIGIISF
>Mature_426_residues
MLAILGFVMMIVFMYLIMSNRLSALIALIVVPIVFALISGFGKDLGEMMIQGVTDLAPTGIMLLFAILYFGIMIDSGLFD
PLIAKILSFVKGDPLKIAVGTAVLTMTISLDGDGTTTYMITIAAMLPLYKRLGMNRLVLAGIAMLGSGVMNIIPWGGPTA
RVLASLKLDTSEVFTPLIPAMIAGILWVIAVAYILGKKERKRLGVISIDHAPSSDPEAAPLKRPALQWFNLLLTVALMAA
LITSLLPLPVLFMTAFAVALMVNYPNVKEQQKRISAHAGNALNVVSMVFAAGIFTGILSGTKMVDAMAHSLVSLIPDAMG
PHLPLITAIVSMPFTFFMSNDAFYFGVLPIIAEAASAYGIDAAEIGRASLLGQPVHLLSPLVPSTYLLVGMAGVSFGDHQ
KFTIKWAVGTTIVMTIAALLIGIISF

Specific function: Transports the free citrate anion. Probably cotransports citrate and at least three or four protons. The citrate uptake is inhibited by the presence of magnesium ions

COG id: COG2851

COG function: function code C; H+/citrate symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitM (TC 2.A.11) transporter family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CITN_BACSU (P42308)

Other databases:

- EMBL:   D83026
- EMBL:   AL009126
- EMBL:   Z46862
- PIR:   D70078
- RefSeq:   NP_391785.2
- EnsemblBacteria:   EBBACT00000001979
- GeneID:   937469
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU39060
- NMPDR:   fig|224308.1.peg.3911
- GenoList:   BSU39060
- GeneTree:   EBGT00050000001369
- HOGENOM:   HBG297065
- ProtClustDB:   CLSK2793898
- BioCyc:   BSUB:BSU39060-MONOMER
- InterPro:   IPR014738
- InterPro:   IPR004680
- PANTHER:   PTHR10283:SF44
- TIGRFAMs:   TIGR00784

Pfam domain/function: PF03600 CitMHS

EC number: NA

Molecular weight: Translated: 45301; Mature: 45301

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x134970d4)-; HASH(0x135b5e18)-; HASH(0x13528cc4)-; HASH(0x1351c248)-; HASH(0x12c11440)-; HASH(0x13088478)-; HASH(0x12c7b050)-; HASH(0x129591b4)-; HASH(0x127f6178)-; HASH(0x1326a74c)-; HASH(0x135ac59c)-; HASH(0x1311acf4)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.3 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.3 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAILGFVMMIVFMYLIMSNRLSALIALIVVPIVFALISGFGKDLGEMMIQGVTDLAPTG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
IMLLFAILYFGIMIDSGLFDPLIAKILSFVKGDPLKIAVGTAVLTMTISLDGDGTTTYMI
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCEEEEEEEEECCCCCHHHHH
TIAAMLPLYKRLGMNRLVLAGIAMLGSGVMNIIPWGGPTARVLASLKLDTSEVFTPLIPA
HHHHHHHHHHHHCCCHHHHHHHHHHCCCHHEEECCCCHHHHHHHHHCCCHHHHHHHHHHH
MIAGILWVIAVAYILGKKERKRLGVISIDHAPSSDPEAAPLKRPALQWFNLLLTVALMAA
HHHHHHHHHHHHHHHCCHHHHHCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LITSLLPLPVLFMTAFAVALMVNYPNVKEQQKRISAHAGNALNVVSMVFAAGIFTGILSG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
TKMVDAMAHSLVSLIPDAMGPHLPLITAIVSMPFTFFMSNDAFYFGVLPIIAEAASAYGI
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHEEECCCCHHHHHHHHHHHHHHHCCC
DAAEIGRASLLGQPVHLLSPLVPSTYLLVGMAGVSFGDHQKFTIKWAVGTTIVMTIAALL
CHHHHCHHHHCCCCHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEEEHHHHHHHHHHHHH
IGIISF
HHHHCH
>Mature Secondary Structure
MLAILGFVMMIVFMYLIMSNRLSALIALIVVPIVFALISGFGKDLGEMMIQGVTDLAPTG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
IMLLFAILYFGIMIDSGLFDPLIAKILSFVKGDPLKIAVGTAVLTMTISLDGDGTTTYMI
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCEEEEEEEEECCCCCHHHHH
TIAAMLPLYKRLGMNRLVLAGIAMLGSGVMNIIPWGGPTARVLASLKLDTSEVFTPLIPA
HHHHHHHHHHHHCCCHHHHHHHHHHCCCHHEEECCCCHHHHHHHHHCCCHHHHHHHHHHH
MIAGILWVIAVAYILGKKERKRLGVISIDHAPSSDPEAAPLKRPALQWFNLLLTVALMAA
HHHHHHHHHHHHHHHCCHHHHHCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LITSLLPLPVLFMTAFAVALMVNYPNVKEQQKRISAHAGNALNVVSMVFAAGIFTGILSG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
TKMVDAMAHSLVSLIPDAMGPHLPLITAIVSMPFTFFMSNDAFYFGVLPIIAEAASAYGI
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHEEECCCCHHHHHHHHHHHHHHHCCC
DAAEIGRASLLGQPVHLLSPLVPSTYLLVGMAGVSFGDHQKFTIKWAVGTTIVMTIAALL
CHHHHCHHHHCCCCHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEEEHHHHHHHHHHHHH
IGIISF
HHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377; 7704256; 8892821