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The map label for this gene is dltE

Identifier: 255767816

GI number: 255767816

Start: 3956492

End: 3957250

Strand: Direct

Name: dltE

Synonym: BSU38540

Alternate gene names: 255767816

Gene position: 3956492-3957250 (Clockwise)

Preceding gene: 16080904

Following gene: 255767817

Centisome position: 93.85

GC content: 48.09

Gene sequence:

>759_bases
ATGAAGATGACAAATAATACGGTTTTAATCACAGGGGGTTCTGCTGGCATCGGGCTTGAACTGGCCAAGCGCCTGCTGGA
ACTTGGCAATGAAGTTATCATTTGCGGACGCAGCGAAGCACGTCTTGCAGAAGCGAAGCAGCAGCTCCCAAACATCCATA
CAAAGCAATGTGATGTTGCAGACCGTTCGCAGCGGGAAGCATTGTATGAATGGGCTTTAAAGGAATATCCGAACTTGAAT
GTTCTCGTCAACAACGCCGGCATTCAAAAGGAAATTGACTTTAAAAAAGGGACAGAGGAGCTTTTTGTGGACGGTGATGA
AATTGAACTTAATTTCCAAGCGCCTGTCCATTTATCCGCCCTTTTCACACCTCATTTGATGAAGCAGCCCGAGGCGGCAA
TCGTTCAGGTCACATCCGGGCTTGCGTTTAACCCGTTAGCTGTTTATCCGGTGTACTGCGCAACAAAAGCGGCACTTCAC
TCGTTCTCGCTTACGCTCAGACACCAGCTCCGCGACACGAGCGTGGAAGTGATTGAAATGGCACCGCCTATGGTGGACAC
GGGCTTAAACCAAAAATCACGCGATAAACAAGGCCTGACGTACCGGGGCATTTCATCTGAAGAATATGTTCAATATTTCT
TGGACGGCTTGAAGGAAGGCAAACAGGAGATTACAAATGAACGTGTTGAAGGTCTTCGGGATGCCACTCGCGCCGATTAT
GACAGGTTATTCGAGCAAATGAACACGCAGGAGAATTAA

Upstream 100 bases:

>100_bases
TTCATCCTGAGCATCTCATAGGACGCGGCTGCATATTTCCTGCTAAGATTTGTAATAGTAAAGGAATCACAGCCAACTTA
ATTAAGAGGTGTTACATCCA

Downstream 100 bases:

>100_bases
TTTCTCCTGCTTTTTTCATATGAATTTCTTACAAATTTGAGCAAACCTATTGCGATTATTTGTTGAAGGTATACAATAGA
ATATAATTATTTTCAAATAA

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MKMTNNTVLITGGSAGIGLELAKRLLELGNEVIICGRSEARLAEAKQQLPNIHTKQCDVADRSQREALYEWALKEYPNLN
VLVNNAGIQKEIDFKKGTEELFVDGDEIELNFQAPVHLSALFTPHLMKQPEAAIVQVTSGLAFNPLAVYPVYCATKAALH
SFSLTLRHQLRDTSVEVIEMAPPMVDTGLNQKSRDKQGLTYRGISSEEYVQYFLDGLKEGKQEITNERVEGLRDATRADY
DRLFEQMNTQEN

Sequences:

>Translated_252_residues
MKMTNNTVLITGGSAGIGLELAKRLLELGNEVIICGRSEARLAEAKQQLPNIHTKQCDVADRSQREALYEWALKEYPNLN
VLVNNAGIQKEIDFKKGTEELFVDGDEIELNFQAPVHLSALFTPHLMKQPEAAIVQVTSGLAFNPLAVYPVYCATKAALH
SFSLTLRHQLRDTSVEVIEMAPPMVDTGLNQKSRDKQGLTYRGISSEEYVQYFLDGLKEGKQEITNERVEGLRDATRADY
DRLFEQMNTQEN
>Mature_252_residues
MKMTNNTVLITGGSAGIGLELAKRLLELGNEVIICGRSEARLAEAKQQLPNIHTKQCDVADRSQREALYEWALKEYPNLN
VLVNNAGIQKEIDFKKGTEELFVDGDEIELNFQAPVHLSALFTPHLMKQPEAAIVQVTSGLAFNPLAVYPVYCATKAALH
SFSLTLRHQLRDTSVEVIEMAPPMVDTGLNQKSRDKQGLTYRGISSEEYVQYFLDGLKEGKQEITNERVEGLRDATRADY
DRLFEQMNTQEN

Specific function: Unknown

COG id: COG3967

COG function: function code M; Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family

Homologues:

Organism=Homo sapiens, GI20149619, Length=240, Percent_Identity=25.8333333333333, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI7706318, Length=178, Percent_Identity=32.0224719101124, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI33667109, Length=225, Percent_Identity=26.2222222222222, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI5031737, Length=193, Percent_Identity=26.9430051813472, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI32483357, Length=194, Percent_Identity=25.7731958762887, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI31542939, Length=201, Percent_Identity=27.8606965174129, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI126723191, Length=180, Percent_Identity=26.1111111111111, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787820, Length=181, Percent_Identity=33.1491712707182, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1787335, Length=198, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=223, Percent_Identity=30.0448430493274, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=195, Percent_Identity=27.6923076923077, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=227, Percent_Identity=29.0748898678414, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=199, Percent_Identity=30.6532663316583, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=197, Percent_Identity=30.9644670050761, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=233, Percent_Identity=29.1845493562232, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=225, Percent_Identity=30.2222222222222, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=201, Percent_Identity=29.3532338308458, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=227, Percent_Identity=27.3127753303965, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=188, Percent_Identity=26.5957446808511, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=200, Percent_Identity=28, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=194, Percent_Identity=28.8659793814433, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=197, Percent_Identity=28.4263959390863, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6322227, Length=227, Percent_Identity=31.2775330396476, Blast_Score=86, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6323882, Length=197, Percent_Identity=30.4568527918782, Blast_Score=82, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6322226, Length=221, Percent_Identity=28.5067873303167, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24580925, Length=196, Percent_Identity=30.6122448979592, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI23397609, Length=212, Percent_Identity=29.7169811320755, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI116007236, Length=207, Percent_Identity=28.0193236714976, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24584752, Length=199, Percent_Identity=31.6582914572864, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21355319, Length=194, Percent_Identity=25.2577319587629, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI281364494, Length=204, Percent_Identity=26.4705882352941, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24647946, Length=208, Percent_Identity=29.8076923076923, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI221331218, Length=193, Percent_Identity=26.4248704663212, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24640492, Length=229, Percent_Identity=26.2008733624454, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24665243, Length=178, Percent_Identity=28.0898876404494, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45553409, Length=207, Percent_Identity=29.4685990338164, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24647948, Length=207, Percent_Identity=29.4685990338164, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28571526, Length=215, Percent_Identity=25.1162790697674, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24640442, Length=197, Percent_Identity=25.8883248730964, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): DLTE_BACSU (P39577)

Other databases:

- EMBL:   X73124
- EMBL:   AL009126
- PIR:   S39656
- RefSeq:   NP_391733.2
- ProteinModelPortal:   P39577
- SMR:   P39577
- EnsemblBacteria:   EBBACT00000003597
- GeneID:   937369
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU38540
- NMPDR:   fig|224308.1.peg.3859
- GenoList:   BSU38540
- GeneTree:   EBGT00050000000462
- HOGENOM:   HBG750976
- PhylomeDB:   P39577
- ProtClustDB:   CLSK536674
- BioCyc:   BSUB:BSU38540-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR19410
- PRINTS:   PR00081
- PRINTS:   PR00080

Pfam domain/function: PF00106 adh_short

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28273; Mature: 28273

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00061 ADH_SHORT

Important sites: ACT_SITE 152-152 BINDING 139-139

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMTNNTVLITGGSAGIGLELAKRLLELGNEVIICGRSEARLAEAKQQLPNIHTKQCDVA
CCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCC
DRSQREALYEWALKEYPNLNVLVNNAGIQKEIDFKKGTEELFVDGDEIELNFQAPVHLSA
CHHHHHHHHHHHHHHCCCCEEEEECCCCCEECCCCCCCHHEEECCCEEEEEEECCEEEHH
LFTPHLMKQPEAAIVQVTSGLAFNPLAVYPVYCATKAALHSFSLTLRHQLRDTSVEVIEM
HHCHHHHCCCCHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
APPMVDTGLNQKSRDKQGLTYRGISSEEYVQYFLDGLKEGKQEITNERVEGLRDATRADY
CCCHHHCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRLFEQMNTQEN
HHHHHHHCCCCC
>Mature Secondary Structure
MKMTNNTVLITGGSAGIGLELAKRLLELGNEVIICGRSEARLAEAKQQLPNIHTKQCDVA
CCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCC
DRSQREALYEWALKEYPNLNVLVNNAGIQKEIDFKKGTEELFVDGDEIELNFQAPVHLSA
CHHHHHHHHHHHHHHCCCCEEEEECCCCCEECCCCCCCHHEEECCCEEEEEEECCEEEHH
LFTPHLMKQPEAAIVQVTSGLAFNPLAVYPVYCATKAALHSFSLTLRHQLRDTSVEVIEM
HHCHHHHCCCCHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
APPMVDTGLNQKSRDKQGLTYRGISSEEYVQYFLDGLKEGKQEITNERVEGLRDATRADY
CCCHHHCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRLFEQMNTQEN
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377; 7797557