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The map label for this gene is yuxL

Identifier: 255767740

GI number: 255767740

Start: 3310763

End: 3312736

Strand: Reverse

Name: yuxL

Synonym: BSU32230

Alternate gene names: 255767740

Gene position: 3312736-3310763 (Counterclockwise)

Preceding gene: 16080277

Following gene: 16080274

Centisome position: 78.58

GC content: 48.43

Gene sequence:

>1974_bases
ATGAAAAAGCTGATAACCGCAGACGACATCACAGCGATTGTCTCTGTGACCGATCCTCAATACGCCCCAGACGGTACCCG
TGCCGCATATGTAAAATCACAAGTAAATCAAGAGAAAGATTCGTATACATCAAATATATGGATCTATGAAACGAAAACGG
GAGGATCTGTTCCTTGGACACATGGAGAAAAGCGAAGCACCGACCCAAGATGGTCTCCGGACGGGCGCACGCTTGCCTTT
ATTTCTGATCGAGAAGGCGATGCGGCACAGCTTTATATCATGAGCACTGAAGGCGGAGAAGCAAGAAAACTGACTGATAT
CCCATATGGCGTGTCAAAGCCGCTATGGTCCCCGGACGGTGAATCGATTCTGGTCACTGTCAGTTTGGGAGAGGGGGAAA
GCATTGATGACCGAGAAAAAACAGAGCAGGACAGCTATGAACCTGTTGAAGTGCAAGGCCTCTCCTACAAACGGGACGGC
AAAGGGCTGACGAGAGGTGCGTATGCCCAGCTTGTGCTTGTCAGCGTAAAGTCGGGTGAGATGAAAGAGCTGACAAGTCA
CAAAGCTGATCATGGTGATCCTGCTTTTTCTCCTGACGGCAAATGGCTTGTTTTCTCAGCTAATTTAACTGAAACAGATG
ATGCCAGCAAGCCGCATGATGTTTACATAATGTCACTGGAGTCTGGAGATCTTAAGCAGGTTACACCTCATCGCGGCTCA
TTCGGATCAAGCTCATTTTCACCAGACGGAAGGTATCTTGCTTTGCTTGGAAATGAAAAGGAATATAAGAATGCTACGCT
CTCAAAGGCGTGGCTCTATGATATCGAACAAGGCCGCCTCACATGTCTTACTGAGATGCTGGACGTTCATTTAGCGGATG
CGCTGATTGGAGATTCATTGATCGGTGGTGCTGAACAGCGCCCGATTTGGACAAAGGACAGCCAAGGGTTTTATGTCATC
GGCACAGATCAAGGCAGTACGGGCATCTATTATATTTCGATTGAAGGCCTTGTGTATCCGATTCGTCTGGAAAAAGAGTA
CATCAATAGCTTTTCTCTTTCACCTGATGAACAGCACTTTATTGCCAGTGTGACAAAGCCGGACAGACCGAGTGAGCTTT
ACAGTATCCCGCTTGGACAGGAAGAGAAACAGCTGACTGGCGCGAATGACAAGTTTGTCAGGGAGCATACGATATCAATA
CCTGAAGAGATTCAATATGCTACAGAAGACGGCGTGATGGTGAACGGCTGGCTGATGAGGCCTGCACAAATGGAAGGTGA
GACAACATATCCACTTATTCTTAACATACACGGCGGTCCGCATATGATGTACGGACATACATATTTTCATGAGTTTCAGG
TGCTGGCGGCGAAAGGATACGCGGTCGTTTATATCAATCCGAGAGGAAGCCACGGCTACGGGCAGGAATTTGTGAATGCG
GTCAGAGGAGATTATGGGGGAAAGGATTATGACGATGTGATGCAGGCTGTGGATGAGGCTATCAAACGAGATCCGCATAT
TGATCCTAAGCGGCTCGGTGTCACGGGCGGAAGCTACGGAGGTTTTATGACCAACTGGATCGTCGGGCAGACGAACCGCT
TTAAAGCTGCCGTTACCCAGCGCTCGATATCAAATTGGATCAGCTTTCACGGCGTCAGTGATATCGGCTATTTCTTTACA
GACTGGCAGCTTGAGCATGACATGTTTGAGGACACAGAAAAGCTCTGGGACCGGTCTCCTTTAAAATACGCAGCAAACGT
GGAGACACCGCTTTTGATACTGCATGGCGAGCGGGATGACCGATGCCCGATCGAGCAGGCGGAGCAGCTGTTTATCGCTC
TGAAAAAAATGGGCAAGGAAACCAAGCTTGTCCGTTTTCCGAATGCATCGCACAATTTATCACGCACCGGACACCCAAGA
CAGCGGATCAAGCGCCTGAATTATATCAGCTCATGGTTTGATCAACATCTCTAA

Upstream 100 bases:

>100_bases
CAAGCGTTCCTCAGCGTCAGCGGAGGGCGCTTTTTTTTGCTGGAGATAAAGGAGTTTTTATTTAGAAAAACGAAATACAT
GTAAAAAGGAGGAGATGAAT

Downstream 100 bases:

>100_bases
TAAAAAAGCCAGGCTGATCAAATATCAGCCTGGCTGCTTTATTAAAAGACTTGTTCTACTTCAACGACACCCGGCACTTC
TTCAAGAAGAGCGCGCTCAA

Product: acylaminoacyl-peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 657; Mature: 657

Protein sequence:

>657_residues
MKKLITADDITAIVSVTDPQYAPDGTRAAYVKSQVNQEKDSYTSNIWIYETKTGGSVPWTHGEKRSTDPRWSPDGRTLAF
ISDREGDAAQLYIMSTEGGEARKLTDIPYGVSKPLWSPDGESILVTVSLGEGESIDDREKTEQDSYEPVEVQGLSYKRDG
KGLTRGAYAQLVLVSVKSGEMKELTSHKADHGDPAFSPDGKWLVFSANLTETDDASKPHDVYIMSLESGDLKQVTPHRGS
FGSSSFSPDGRYLALLGNEKEYKNATLSKAWLYDIEQGRLTCLTEMLDVHLADALIGDSLIGGAEQRPIWTKDSQGFYVI
GTDQGSTGIYYISIEGLVYPIRLEKEYINSFSLSPDEQHFIASVTKPDRPSELYSIPLGQEEKQLTGANDKFVREHTISI
PEEIQYATEDGVMVNGWLMRPAQMEGETTYPLILNIHGGPHMMYGHTYFHEFQVLAAKGYAVVYINPRGSHGYGQEFVNA
VRGDYGGKDYDDVMQAVDEAIKRDPHIDPKRLGVTGGSYGGFMTNWIVGQTNRFKAAVTQRSISNWISFHGVSDIGYFFT
DWQLEHDMFEDTEKLWDRSPLKYAANVETPLLILHGERDDRCPIEQAEQLFIALKKMGKETKLVRFPNASHNLSRTGHPR
QRIKRLNYISSWFDQHL

Sequences:

>Translated_657_residues
MKKLITADDITAIVSVTDPQYAPDGTRAAYVKSQVNQEKDSYTSNIWIYETKTGGSVPWTHGEKRSTDPRWSPDGRTLAF
ISDREGDAAQLYIMSTEGGEARKLTDIPYGVSKPLWSPDGESILVTVSLGEGESIDDREKTEQDSYEPVEVQGLSYKRDG
KGLTRGAYAQLVLVSVKSGEMKELTSHKADHGDPAFSPDGKWLVFSANLTETDDASKPHDVYIMSLESGDLKQVTPHRGS
FGSSSFSPDGRYLALLGNEKEYKNATLSKAWLYDIEQGRLTCLTEMLDVHLADALIGDSLIGGAEQRPIWTKDSQGFYVI
GTDQGSTGIYYISIEGLVYPIRLEKEYINSFSLSPDEQHFIASVTKPDRPSELYSIPLGQEEKQLTGANDKFVREHTISI
PEEIQYATEDGVMVNGWLMRPAQMEGETTYPLILNIHGGPHMMYGHTYFHEFQVLAAKGYAVVYINPRGSHGYGQEFVNA
VRGDYGGKDYDDVMQAVDEAIKRDPHIDPKRLGVTGGSYGGFMTNWIVGQTNRFKAAVTQRSISNWISFHGVSDIGYFFT
DWQLEHDMFEDTEKLWDRSPLKYAANVETPLLILHGERDDRCPIEQAEQLFIALKKMGKETKLVRFPNASHNLSRTGHPR
QRIKRLNYISSWFDQHL
>Mature_657_residues
MKKLITADDITAIVSVTDPQYAPDGTRAAYVKSQVNQEKDSYTSNIWIYETKTGGSVPWTHGEKRSTDPRWSPDGRTLAF
ISDREGDAAQLYIMSTEGGEARKLTDIPYGVSKPLWSPDGESILVTVSLGEGESIDDREKTEQDSYEPVEVQGLSYKRDG
KGLTRGAYAQLVLVSVKSGEMKELTSHKADHGDPAFSPDGKWLVFSANLTETDDASKPHDVYIMSLESGDLKQVTPHRGS
FGSSSFSPDGRYLALLGNEKEYKNATLSKAWLYDIEQGRLTCLTEMLDVHLADALIGDSLIGGAEQRPIWTKDSQGFYVI
GTDQGSTGIYYISIEGLVYPIRLEKEYINSFSLSPDEQHFIASVTKPDRPSELYSIPLGQEEKQLTGANDKFVREHTISI
PEEIQYATEDGVMVNGWLMRPAQMEGETTYPLILNIHGGPHMMYGHTYFHEFQVLAAKGYAVVYINPRGSHGYGQEFVNA
VRGDYGGKDYDDVMQAVDEAIKRDPHIDPKRLGVTGGSYGGFMTNWIVGQTNRFKAAVTQRSISNWISFHGVSDIGYFFT
DWQLEHDMFEDTEKLWDRSPLKYAANVETPLLILHGERDDRCPIEQAEQLFIALKKMGKETKLVRFPNASHNLSRTGHPR
QRIKRLNYISSWFDQHL

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3 And K). Necessary For The Colicins To Reach Their Respective Targets After Initial Binding To The Bacteria. [C]

COG id: COG1506

COG function: function code E; Dipeptidyl aminopeptidases/acylaminoacyl-peptidases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9B family

Homologues:

Organism=Homo sapiens, GI23510451, Length=246, Percent_Identity=30.4878048780488, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI194394146, Length=243, Percent_Identity=25.9259259259259, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI18450280, Length=242, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI37577089, Length=242, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI16933540, Length=267, Percent_Identity=25.4681647940075, Blast_Score=71, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI25149159, Length=296, Percent_Identity=30.7432432432432, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI25144537, Length=363, Percent_Identity=23.1404958677686, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI25144540, Length=363, Percent_Identity=23.1404958677686, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17552908, Length=302, Percent_Identity=26.4900662251656, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17564632, Length=215, Percent_Identity=29.7674418604651, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17564634, Length=215, Percent_Identity=29.7674418604651, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17508019, Length=246, Percent_Identity=26.8292682926829, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17508017, Length=246, Percent_Identity=26.8292682926829, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17550672, Length=310, Percent_Identity=24.5161290322581, Blast_Score=70, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25144543, Length=214, Percent_Identity=24.2990654205607, Blast_Score=66, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6324793, Length=320, Percent_Identity=25.3125, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI45551969, Length=244, Percent_Identity=27.8688524590164, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI45550825, Length=244, Percent_Identity=27.8688524590164, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI45553511, Length=244, Percent_Identity=27.8688524590164, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24582257, Length=224, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YUXL_BACSU (P39839)

Other databases:

- EMBL:   AL009126
- EMBL:   X04603
- PIR:   E70025
- RefSeq:   NP_391103.2
- ProteinModelPortal:   P39839
- MEROPS:   S09.071
- EnsemblBacteria:   EBBACT00000000099
- GeneID:   936648
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU32230
- NMPDR:   fig|224308.1.peg.3229
- GenoList:   BSU32230
- GeneTree:   EBGT00070000032203
- HOGENOM:   HBG531533
- ProtClustDB:   CLSK887827
- BioCyc:   BSUB:BSU32230-MONOMER
- InterPro:   IPR011042
- InterPro:   IPR011659
- InterPro:   IPR001375
- Gene3D:   G3DSA:2.120.10.30

Pfam domain/function: PF07676 PD40; PF00326 Peptidase_S9

EC number: NA

Molecular weight: Translated: 73700; Mature: 73700

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: ACT_SITE 518-518 ACT_SITE 631-631

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLITADDITAIVSVTDPQYAPDGTRAAYVKSQVNQEKDSYTSNIWIYETKTGGSVPWT
CCCEEECCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCC
HGEKRSTDPRWSPDGRTLAFISDREGDAAQLYIMSTEGGEARKLTDIPYGVSKPLWSPDG
CCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCCCEEECCCCCCCCCCCCCCC
ESILVTVSLGEGESIDDREKTEQDSYEPVEVQGLSYKRDGKGLTRGAYAQLVLVSVKSGE
CEEEEEEECCCCCCCCCHHHCCCCCCCCEEEECCCEECCCCCCCCCCEEEEEEEEECCCC
MKELTSHKADHGDPAFSPDGKWLVFSANLTETDDASKPHDVYIMSLESGDLKQVTPHRGS
HHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCEECCCCCCC
FGSSSFSPDGRYLALLGNEKEYKNATLSKAWLYDIEQGRLTCLTEMLDVHLADALIGDSL
CCCCCCCCCCCEEEEECCCHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
IGGAEQRPIWTKDSQGFYVIGTDQGSTGIYYISIEGLVYPIRLEKEYINSFSLSPDEQHF
CCCCCCCCEEECCCCCEEEEECCCCCCCEEEEEECCEEEEEEECHHHHHCCCCCCCCCEE
IASVTKPDRPSELYSIPLGQEEKQLTGANDKFVREHTISIPEEIQYATEDGVMVNGWLMR
EEECCCCCCCCCEEECCCCCCHHHHCCCCCCEEHHHCCCCHHHHHHHCCCCEEEEEEEEC
PAQMEGETTYPLILNIHGGPHMMYGHTYFHEFQVLAAKGYAVVYINPRGSHGYGQEFVNA
CCCCCCCCCCEEEEEECCCCEEEECCHHHEEEEEEEECCEEEEEEECCCCCCHHHHHHHH
VRGDYGGKDYDDVMQAVDEAIKRDPHIDPKRLGVTGGSYGGFMTNWIVGQTNRFKAAVTQ
HHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHEECCCCCCCCCHHEEEECCCCCHHHHHHH
RSISNWISFHGVSDIGYFFTDWQLEHDMFEDTEKLWDRSPLKYAANVETPLLILHGERDD
HHHHHHHHHCCCCCCCEEEEEEEECHHHHHHHHHHHCCCCCEEECCCCCCEEEEECCCCC
RCPIEQAEQLFIALKKMGKETKLVRFPNASHNLSRTGHPRQRIKRLNYISSWFDQHL
CCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKLITADDITAIVSVTDPQYAPDGTRAAYVKSQVNQEKDSYTSNIWIYETKTGGSVPWT
CCCEEECCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCC
HGEKRSTDPRWSPDGRTLAFISDREGDAAQLYIMSTEGGEARKLTDIPYGVSKPLWSPDG
CCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCCCEEECCCCCCCCCCCCCCC
ESILVTVSLGEGESIDDREKTEQDSYEPVEVQGLSYKRDGKGLTRGAYAQLVLVSVKSGE
CEEEEEEECCCCCCCCCHHHCCCCCCCCEEEECCCEECCCCCCCCCCEEEEEEEEECCCC
MKELTSHKADHGDPAFSPDGKWLVFSANLTETDDASKPHDVYIMSLESGDLKQVTPHRGS
HHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCEECCCCCCC
FGSSSFSPDGRYLALLGNEKEYKNATLSKAWLYDIEQGRLTCLTEMLDVHLADALIGDSL
CCCCCCCCCCCEEEEECCCHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
IGGAEQRPIWTKDSQGFYVIGTDQGSTGIYYISIEGLVYPIRLEKEYINSFSLSPDEQHF
CCCCCCCCEEECCCCCEEEEECCCCCCCEEEEEECCEEEEEEECHHHHHCCCCCCCCCEE
IASVTKPDRPSELYSIPLGQEEKQLTGANDKFVREHTISIPEEIQYATEDGVMVNGWLMR
EEECCCCCCCCCEEECCCCCCHHHHCCCCCCEEHHHCCCCHHHHHHHCCCCEEEEEEEEC
PAQMEGETTYPLILNIHGGPHMMYGHTYFHEFQVLAAKGYAVVYINPRGSHGYGQEFVNA
CCCCCCCCCCEEEEEECCCCEEEECCHHHEEEEEEEECCEEEEEEECCCCCCHHHHHHHH
VRGDYGGKDYDDVMQAVDEAIKRDPHIDPKRLGVTGGSYGGFMTNWIVGQTNRFKAAVTQ
HHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHEECCCCCCCCCHHEEEECCCCCHHHHHHH
RSISNWISFHGVSDIGYFFTDWQLEHDMFEDTEKLWDRSPLKYAANVETPLLILHGERDD
HHHHHHHHHCCCCCCCEEEEEEEECHHHHHHHHHHHCCCCCEEECCCCCCEEEEECCCCC
RCPIEQAEQLFIALKKMGKETKLVRFPNASHNLSRTGHPRQRIKRLNYISSWFDQHL
CCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 3098560