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The map label for this gene is yugS

Identifier: 255767709

GI number: 255767709

Start: 3216163

End: 3217452

Strand: Reverse

Name: yugS

Synonym: BSU31300

Alternate gene names: 255767709

Gene position: 3217452-3216163 (Counterclockwise)

Preceding gene: 16080183

Following gene: 255767708

Centisome position: 76.32

GC content: 42.95

Gene sequence:

>1290_bases
TTGCTTATTTTACAATTGATCGCCATTTTTGTTTTGATTGGCATTACGGCTGTTTTCGTTGCAGCGGAATTTGCGATCGT
CAAAATCAGAGGTTCAAAAATCAATCAGCTCATCGAAAGCGGTGACAGCCGAGCACTAGCCGCACATAAAATCATCTCCA
ATCTTGACGAGTATTTATCAGCCTGCCAGCTCGGGATTACGATTACAGCCCTCGGCCTTGGGTGGCTTGGTGAACCTACA
TTTGAACGTTTTCTTCATCCCTTATTTACAATGACAGGCATACCGGAACCGTTTAACCACATTGTCACATTTGTAGTTGC
ATTTATCATCGTCACTTTTTTGCATGTGGTGATGGGGGAGCTTGCCCCGAAAACGGTTTCTATTCAAAAAGCTGAAGCTG
TAAGCTTATGGATTGCAAAGCCGCTGATCTGGTTTTATAAAATCACGTACCCGTTTATTAAAGCATTAAACGGCTCTGCA
AGTTTTCTTGTGAAATTGTTTGGCTTTCATTCGGTAAAGGAGCATCAGGTTGTCATCAGCGAAGAGGAACTAAGGCTGAT
CCTTTCTGAAAGCTATGAAAAGGGAGAAATCAATCAGTCTGAATTCCGCTATGTAAATAAGATTTTTGAATTTGACAACC
GGGTAGCGAGAGAGATTATGATTCCGCGGACAGAAATTGCGGTTATCTCTCTGGAGCAGTCGCTTGAAGAGGCAATTCAT
CACATCATTAATGAACGGTATACACGCTACCCTGTCATCAAAGATGACAAGGATCATATTTTAGGGATCATCAACAGCAA
AGATATGTTTAAAGCTTATTTTCTCGGCCAGCCGATAAAGCTGAATCAAATCATGAGGCCCGTTATCAGAGTCATTGAAA
GCATTCCTGTTCAGCAGCTTTTAATCCGCATGCAGAAGGAGCGGATTCACATGGCGATTCTTGTCGATGAATACGGGGGA
ACGGCGGGGCTTGTCACTGTAGAGGATATTATCGAGGAAATCGTCGGGGAAATCCGCGATGAGTATGATCAGGATGAAAC
ACCGCACATCCTGAAAAAGGGCGAGCACCATTATGTGATGGATGGAAAAGCGCTAATAGACGAAGTGAATGACCTTCTCG
ACATTGCGATTGAAAATGAAGAAATTGATACGATTGCAGGCTGGCTTCTAACGCAAAAAATGGAGCTGAAAGCAGGGGAT
GTGATACACGCGGAGGGCTGTGAATTTAAAATCCTCGACGCCGAAGATCACCACATCCGTTTTGTAGAAATAAAAAAAAC
TGATTTTTGA

Upstream 100 bases:

>100_bases
CTGTTTGAACTACTTCGTTTTGTGATGATTTTCTTAAACGGTCGTGATGAGAATTAACGTTAAGGAGGTGGCCCCTTACC
ATTTATGGTAAGGGCTTTTT

Downstream 100 bases:

>100_bases
TAAAAAACAGCCGGGGAACAAACGGCTGTTTTTTGTGTCATCAAGTCATTTCTTAAAAAGCAATGCTGTAAAGACCTTTT
TCTACATAGGATATATAAGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MLILQLIAIFVLIGITAVFVAAEFAIVKIRGSKINQLIESGDSRALAAHKIISNLDEYLSACQLGITITALGLGWLGEPT
FERFLHPLFTMTGIPEPFNHIVTFVVAFIIVTFLHVVMGELAPKTVSIQKAEAVSLWIAKPLIWFYKITYPFIKALNGSA
SFLVKLFGFHSVKEHQVVISEEELRLILSESYEKGEINQSEFRYVNKIFEFDNRVAREIMIPRTEIAVISLEQSLEEAIH
HIINERYTRYPVIKDDKDHILGIINSKDMFKAYFLGQPIKLNQIMRPVIRVIESIPVQQLLIRMQKERIHMAILVDEYGG
TAGLVTVEDIIEEIVGEIRDEYDQDETPHILKKGEHHYVMDGKALIDEVNDLLDIAIENEEIDTIAGWLLTQKMELKAGD
VIHAEGCEFKILDAEDHHIRFVEIKKTDF

Sequences:

>Translated_429_residues
MLILQLIAIFVLIGITAVFVAAEFAIVKIRGSKINQLIESGDSRALAAHKIISNLDEYLSACQLGITITALGLGWLGEPT
FERFLHPLFTMTGIPEPFNHIVTFVVAFIIVTFLHVVMGELAPKTVSIQKAEAVSLWIAKPLIWFYKITYPFIKALNGSA
SFLVKLFGFHSVKEHQVVISEEELRLILSESYEKGEINQSEFRYVNKIFEFDNRVAREIMIPRTEIAVISLEQSLEEAIH
HIINERYTRYPVIKDDKDHILGIINSKDMFKAYFLGQPIKLNQIMRPVIRVIESIPVQQLLIRMQKERIHMAILVDEYGG
TAGLVTVEDIIEEIVGEIRDEYDQDETPHILKKGEHHYVMDGKALIDEVNDLLDIAIENEEIDTIAGWLLTQKMELKAGD
VIHAEGCEFKILDAEDHHIRFVEIKKTDF
>Mature_429_residues
MLILQLIAIFVLIGITAVFVAAEFAIVKIRGSKINQLIESGDSRALAAHKIISNLDEYLSACQLGITITALGLGWLGEPT
FERFLHPLFTMTGIPEPFNHIVTFVVAFIIVTFLHVVMGELAPKTVSIQKAEAVSLWIAKPLIWFYKITYPFIKALNGSA
SFLVKLFGFHSVKEHQVVISEEELRLILSESYEKGEINQSEFRYVNKIFEFDNRVAREIMIPRTEIAVISLEQSLEEAIH
HIINERYTRYPVIKDDKDHILGIINSKDMFKAYFLGQPIKLNQIMRPVIRVIESIPVQQLLIRMQKERIHMAILVDEYGG
TAGLVTVEDIIEEIVGEIRDEYDQDETPHILKKGEHHYVMDGKALIDEVNDLLDIAIENEEIDTIAGWLLTQKMELKAGD
VIHAEGCEFKILDAEDHHIRFVEIKKTDF

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains

Homologues:

Organism=Homo sapiens, GI310128564, Length=394, Percent_Identity=46.7005076142132, Blast_Score=391, Evalue=1e-109,
Organism=Escherichia coli, GI1790664, Length=429, Percent_Identity=21.9114219114219, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1786879, Length=253, Percent_Identity=32.8063241106719, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI145693175, Length=412, Percent_Identity=21.8446601941748, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1788119, Length=236, Percent_Identity=27.9661016949153, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87082033, Length=231, Percent_Identity=26.4069264069264, Blast_Score=92, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YUGS_BACSU (O05241)

Other databases:

- EMBL:   Z93935
- EMBL:   AL009126
- PIR:   G70011
- RefSeq:   NP_391008.2
- ProteinModelPortal:   O05241
- EnsemblBacteria:   EBBACT00000001204
- GeneID:   937160
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU31300
- NMPDR:   fig|224308.1.peg.3133
- GenoList:   BSU31300
- GeneTree:   EBGT00070000032069
- HOGENOM:   HBG673071
- ProtClustDB:   CLSK887788
- BioCyc:   BSUB:BSU31300-MONOMER
- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170
- Gene3D:   G3DSA:3.30.465.10
- SMART:   SM00116

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21

EC number: NA

Molecular weight: Translated: 48903; Mature: 48903

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS51371 CBS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1146243c)-; HASH(0x12027f8c)-; HASH(0xff6eafc)-; HASH(0x1205b4b0)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLILQLIAIFVLIGITAVFVAAEFAIVKIRGSKINQLIESGDSRALAAHKIISNLDEYLS
CHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ACQLGITITALGLGWLGEPTFERFLHPLFTMTGIPEPFNHIVTFVVAFIIVTFLHVVMGE
HHHHCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LAPKTVSIQKAEAVSLWIAKPLIWFYKITYPFIKALNGSASFLVKLFGFHSVKEHQVVIS
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEC
EEELRLILSESYEKGEINQSEFRYVNKIFEFDNRVAREIMIPRTEIAVISLEQSLEEAIH
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEHHHHHHHHHH
HIINERYTRYPVIKDDKDHILGIINSKDMFKAYFLGQPIKLNQIMRPVIRVIESIPVQQL
HHHHCCHHCCCCCCCCCCCEEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHH
LIRMQKERIHMAILVDEYGGTAGLVTVEDIIEEIVGEIRDEYDQDETPHILKKGEHHYVM
HHHHHHHHEEEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEEE
DGKALIDEVNDLLDIAIENEEIDTIAGWLLTQKMELKAGDVIHAEGCEFKILDAEDHHIR
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCCCCEEE
FVEIKKTDF
EEEEECCCH
>Mature Secondary Structure
MLILQLIAIFVLIGITAVFVAAEFAIVKIRGSKINQLIESGDSRALAAHKIISNLDEYLS
CHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ACQLGITITALGLGWLGEPTFERFLHPLFTMTGIPEPFNHIVTFVVAFIIVTFLHVVMGE
HHHHCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LAPKTVSIQKAEAVSLWIAKPLIWFYKITYPFIKALNGSASFLVKLFGFHSVKEHQVVIS
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEC
EEELRLILSESYEKGEINQSEFRYVNKIFEFDNRVAREIMIPRTEIAVISLEQSLEEAIH
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEHHHHHHHHHH
HIINERYTRYPVIKDDKDHILGIINSKDMFKAYFLGQPIKLNQIMRPVIRVIESIPVQQL
HHHHCCHHCCCCCCCCCCCEEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHH
LIRMQKERIHMAILVDEYGGTAGLVTVEDIIEEIVGEIRDEYDQDETPHILKKGEHHYVM
HHHHHHHHEEEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEEE
DGKALIDEVNDLLDIAIENEEIDTIAGWLLTQKMELKAGDVIHAEGCEFKILDAEDHHIR
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCCCCEEE
FVEIKKTDF
EEEEECCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377